RPS2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0051443Biological processpositive regulation of ubiquitin-protein transferase activity
GO_0006412Biological processtranslation
GO_0002181Biological processcytoplasmic translation
GO_0005730Cellular componentnucleolus
GO_0022626Cellular componentcytosolic ribosome
GO_0022627Cellular componentcytosolic small ribosomal subunit
GO_0016020Cellular componentmembrane
GO_0070062Cellular componentextracellular exosome
GO_0005654Cellular componentnucleoplasm
GO_0005925Cellular componentfocal adhesion
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0019899Molecular functionenzyme binding
GO_0045296Molecular functioncadherin binding
GO_0003729Molecular functionmRNA binding
GO_0003735Molecular functionstructural constituent of ribosome
GO_0003723Molecular functionRNA binding
GO_0017134Molecular functionfibroblast growth factor binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameRPS2
Protein nameRibosomal protein S2
Small ribosomal subunit protein uS5 (40S ribosomal protein S2)
Small ribosomal subunit protein uS5 (40S ribosomal protein S2) (40S ribosomal protein S4) (Protein LLRep3)
RPS2 protein
SynonymshCG_1990006
RPS4
OK/KNS-cl.7
DescriptionFUNCTION: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell . The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules . The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain . The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel . Plays a role in the assembly and function of the 40S ribosomal subunit (By similarity). Mutations in this protein affects the control of translational fidelity (By similarity). Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly (By similarity). .

AccessionsENST00000709238.1
ENST00000530225.5
ENST00000527302.1
Q8N5L9
I3L404
ENST00000343262.9
E9PQD7
E9PM36
ENST00000526586.6
Q8NI61
Q3KQT6
P15880
Q9BSW5
ENST00000529806.5
H0YE27
E9PMM9
H0YEN5
ENST00000563194.1
ENST00000532746.5
E9PPT0
Q6IPX5
ENST00000526522.5
ENST00000533186.5
H3BNG3