pyroptotic inflammatory response

I. Literature review

[source]
Namepyroptotic inflammatory response
IDGO_0070269
collection_id

Biological process

Description

A gasdermin-dependent inflammatory response that is associated with the generation of pyrogenic mediators such as IL-1beta and IL-18. Gasdermins are activated by caspase-1 or caspase-4/11, or by certain granzymes. In some, but not all cells, it can lead to pyroptotic programmed cell death.

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Genes