RPSA report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0000028Biological processribosomal small subunit assembly
GO_0006412Biological processtranslation
GO_0007155Biological processcell adhesion
GO_0046718Biological processsymbiont entry into host cell
GO_0002181Biological processcytoplasmic translation
GO_0140374Biological processantiviral innate immune response
GO_0022626Cellular componentcytosolic ribosome
GO_0005886Cellular componentplasma membrane
GO_0022627Cellular componentcytosolic small ribosomal subunit
GO_0016020Cellular componentmembrane
GO_0070062Cellular componentextracellular exosome
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0003677Molecular functionDNA binding
GO_0043022Molecular functionribosome binding
GO_0001618Molecular functionvirus receptor activity
GO_0003735Molecular functionstructural constituent of ribosome
GO_0005055Molecular functionlaminin receptor activity
GO_0003723Molecular functionRNA binding
GO_0043236Molecular functionlaminin binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameRPSA
Protein nameSmall ribosomal subunit protein uS2 (37 kDa laminin receptor precursor) (37LRP) (37/67 kDa laminin receptor) (LRP/LR) (67 kDa laminin receptor) (67LR) (Laminin receptor 1) (LamR) (Laminin-binding protein precursor p40) (LBP/p40)
Small ribosomal subunit protein uS2 (37 kDa laminin receptor precursor) (37LRP) (37/67 kDa laminin receptor) (LRP/LR) (40S ribosomal protein SA) (67 kDa laminin receptor) (67LR) (Colon carcinoma laminin-binding protein) (Laminin receptor 1) (LamR) (Laminin-binding protein precursor p40) (LBP/p40) (Multidrug resistance-associated protein MGr1-Ag) (NEM/1CHD4)
Ribosomal protein SA
40S ribosomal protein SA
SynonymshCG_1997894
LAMR1
LAMBR
DescriptionFUNCTION: Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Acts as a PPP1R16B-dependent substrate of PPP1CA. .; FUNCTION: (Microbial infection) Acts as a receptor for the Adeno-associated viruses 2,3,8 and 9. .; FUNCTION: (Microbial infection) Acts as a receptor for the Dengue virus. .; FUNCTION: (Microbial infection) Acts as a receptor for the Sindbis virus. .; FUNCTION: (Microbial infection) Acts as a receptor for the Venezuelan equine encephalitis virus. .; FUNCTION: (Microbial infection) Acts as a receptor for the pathogenic prion protein. .; FUNCTION: (Microbial infection) Acts as a receptor for bacteria. .

FUNCTION: Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteria. Acts as a PPP1R16B-dependent substrate of PPP1CA. .

FUNCTION: Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteria. Acts as a PPP1R16B-dependent substrate of PPP1CA. .

FUNCTION: Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteria. Acts as a PPP1R16B-dependent substrate of PPP1CA. .

AccessionsA0A8V8TMX1
Q96RS2
ENST00000697753.1
F8WD59
C9J9K3
A0A8V8TLA4
ENST00000458478.5
ENST00000301821.11
ENST00000697816.1
A0A8V8TMZ8
ENST00000458478.6
ENST00000697729.1
ENST00000443003.2
ENST00000697731.1
A0A8V8TMP3
A0A0C4DG17
ENST00000697728.1
ENST00000697754.1
P08865
ENST00000697730.1
ENST00000444512.2