PRRC2C | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	49 studies	48% ± 16%	Explore
B cell	43 studies	49% ± 14%	Explore
fibroblast	42 studies	43% ± 15%	Explore
natural killer cell	41 studies	50% ± 15%	Explore
T cell	37 studies	44% ± 17%	Explore
macrophage	37 studies	43% ± 15%	Explore
CD8-positive, alpha-beta T cell	37 studies	49% ± 15%	Explore
pericyte	36 studies	41% ± 15%	Explore
CD4-positive, alpha-beta T cell	35 studies	49% ± 15%	Explore
smooth muscle cell	29 studies	37% ± 11%	Explore
conventional dendritic cell	28 studies	46% ± 16%	Explore
regulatory T cell	27 studies	55% ± 13%	Explore
dendritic cell	26 studies	47% ± 22%	Explore
classical monocyte	26 studies	42% ± 16%	Explore
mast cell	24 studies	42% ± 17%	Explore
non-classical monocyte	24 studies	44% ± 16%	Explore
epithelial cell	23 studies	42% ± 19%	Explore
basal cell	22 studies	42% ± 17%	Explore
monocyte	21 studies	42% ± 13%	Explore
mature NK T cell	21 studies	47% ± 12%	Explore
plasmacytoid dendritic cell	21 studies	51% ± 15%	Explore
memory B cell	20 studies	54% ± 13%	Explore
naive B cell	20 studies	50% ± 15%	Explore
plasma cell	19 studies	36% ± 12%	Explore
endothelial cell of lymphatic vessel	19 studies	42% ± 14%	Explore
gamma-delta T cell	19 studies	54% ± 17%	Explore
astrocyte	19 studies	38% ± 15%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	18 studies	52% ± 16%	Explore
ciliated cell	18 studies	42% ± 16%	Explore
CD16-negative, CD56-bright natural killer cell, human	16 studies	54% ± 18%	Explore
mucosal invariant T cell	16 studies	53% ± 15%	Explore
CD16-positive, CD56-dim natural killer cell, human	16 studies	55% ± 15%	Explore
connective tissue cell	16 studies	40% ± 13%	Explore
myeloid cell	16 studies	46% ± 15%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	15 studies	56% ± 13%	Explore
oligodendrocyte	15 studies	40% ± 17%	Explore
capillary endothelial cell	15 studies	40% ± 11%	Explore
microglial cell	15 studies	47% ± 14%	Explore
myofibroblast cell	14 studies	39% ± 9%	Explore
effector memory CD8-positive, alpha-beta T cell	13 studies	55% ± 18%	Explore
CD4-positive, alpha-beta memory T cell	13 studies	57% ± 13%	Explore
CD8-positive, alpha-beta memory T cell	13 studies	60% ± 12%	Explore
oligodendrocyte precursor cell	13 studies	39% ± 15%	Explore
endothelial cell of artery	13 studies	44% ± 11%	Explore
vein endothelial cell	13 studies	47% ± 14%	Explore
endothelial cell of vascular tree	13 studies	45% ± 15%	Explore
plasmablast	12 studies	51% ± 24%	Explore
type I pneumocyte	11 studies	38% ± 14%	Explore
type II pneumocyte	11 studies	34% ± 12%	Explore
club cell	11 studies	37% ± 14%	Explore
secretory cell	11 studies	45% ± 16%	Explore
leukocyte	11 studies	47% ± 14%	Explore
GABAergic neuron	11 studies	45% ± 23%	Explore
glutamatergic neuron	11 studies	49% ± 24%	Explore
mesothelial cell	11 studies	40% ± 10%	Explore
abnormal cell	10 studies	49% ± 19%	Explore
neuron	10 studies	48% ± 15%	Explore
innate lymphoid cell	9 studies	50% ± 16%	Explore
progenitor cell	9 studies	42% ± 11%	Explore
alveolar macrophage	8 studies	38% ± 13%	Explore
respiratory goblet cell	8 studies	45% ± 13%	Explore
effector CD8-positive, alpha-beta T cell	8 studies	55% ± 13%	Explore
goblet cell	8 studies	36% ± 22%	Explore
T follicular helper cell	8 studies	51% ± 11%	Explore
amacrine cell	8 studies	39% ± 12%	Explore
retinal rod cell	8 studies	29% ± 6%	Explore
adipocyte	8 studies	33% ± 12%	Explore
neutrophil	7 studies	23% ± 8%	Explore
platelet	7 studies	33% ± 15%	Explore
hematopoietic stem cell	7 studies	53% ± 14%	Explore
precursor B cell	7 studies	51% ± 13%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	6 studies	41% ± 8%	Explore
hematopoietic precursor cell	6 studies	55% ± 22%	Explore
ionocyte	6 studies	37% ± 13%	Explore
effector CD4-positive, alpha-beta T cell	6 studies	57% ± 10%	Explore
mononuclear phagocyte	6 studies	45% ± 13%	Explore
interneuron	6 studies	57% ± 20%	Explore
retinal ganglion cell	6 studies	41% ± 17%	Explore
lymphocyte	6 studies	57% ± 13%	Explore
immature B cell	6 studies	51% ± 6%	Explore
retina horizontal cell	6 studies	41% ± 12%	Explore
retinal cone cell	6 studies	34% ± 14%	Explore
Mueller cell	6 studies	31% ± 8%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	66% ± 13%	Explore
CD4-positive helper T cell	5 studies	48% ± 20%	Explore
central memory CD8-positive, alpha-beta T cell	5 studies	53% ± 13%	Explore
exhausted T cell	5 studies	61% ± 13%	Explore
kidney distal convoluted tubule epithelial cell	5 studies	29% ± 9%	Explore
enteroendocrine cell	5 studies	37% ± 10%	Explore
transit amplifying cell	5 studies	33% ± 23%	Explore
retinal bipolar neuron	5 studies	38% ± 10%	Explore
kidney loop of Henle epithelial cell	5 studies	25% ± 5%	Explore
pro-B cell	5 studies	52% ± 10%	Explore
brush cell	5 studies	40% ± 18%	Explore
T-helper 17 cell	5 studies	56% ± 11%	Explore
adventitial cell	5 studies	34% ± 11%	Explore
double negative thymocyte	5 studies	68% ± 10%	Explore
hepatocyte	5 studies	48% ± 25%	Explore
deuterosomal cell	4 studies	36% ± 14%	Explore
duct epithelial cell	4 studies	32% ± 10%	Explore
precursor cell	4 studies	49% ± 7%	Explore
squamous epithelial cell	4 studies	44% ± 23%	Explore
pancreatic A cell	4 studies	62% ± 19%	Explore
epithelial cell of proximal tubule	4 studies	30% ± 10%	Explore
renal alpha-intercalated cell	4 studies	28% ± 10%	Explore
glial cell	4 studies	41% ± 13%	Explore
granule cell	4 studies	38% ± 2%	Explore
erythroblast	4 studies	46% ± 18%	Explore
cardiac muscle cell	4 studies	21% ± 3%	Explore
intermediate monocyte	4 studies	52% ± 24%	Explore
IgA plasma cell	4 studies	28% ± 8%	Explore
IgG plasma cell	4 studies	25% ± 8%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	47% ± 14%	Explore
myoepithelial cell	4 studies	44% ± 10%	Explore
granulocyte	4 studies	44% ± 7%	Explore
luminal cell of prostate epithelium	4 studies	29% ± 8%	Explore
erythrocyte	4 studies	44% ± 7%	Explore
keratinocyte	4 studies	26% ± 6%	Explore
renal principal cell	4 studies	27% ± 6%	Explore
CD4-positive, alpha-beta cytotoxic T cell	3 studies	45% ± 15%	Explore
hillock cell	3 studies	37% ± 10%	Explore
pancreatic D cell	3 studies	53% ± 29%	Explore
type B pancreatic cell	3 studies	62% ± 21%	Explore
monocyte-derived dendritic cell	3 studies	48% ± 19%	Explore
glomerular endothelial cell	3 studies	39% ± 4%	Explore
podocyte	3 studies	44% ± 9%	Explore
differentiation-committed oligodendrocyte precursor	3 studies	50% ± 3%	Explore
enterocyte	3 studies	26% ± 2%	Explore
intestinal crypt stem cell	3 studies	27% ± 3%	Explore
neural crest cell	3 studies	43% ± 8%	Explore
GABAergic interneuron	3 studies	47% ± 10%	Explore
extravillous trophoblast	3 studies	63% ± 22%	Explore
placental villous trophoblast	3 studies	78% ± 19%	Explore
retinal pigment epithelial cell	3 studies	48% ± 22%	Explore
tissue-resident macrophage	3 studies	46% ± 16%	Explore
GABAergic amacrine cell	3 studies	37% ± 7%	Explore
OFF-bipolar cell	3 studies	40% ± 7%	Explore
ON-bipolar cell	3 studies	41% ± 5%	Explore
glycinergic amacrine cell	3 studies	34% ± 1%	Explore
rod bipolar cell	3 studies	43% ± 7%	Explore
inflammatory macrophage	3 studies	31% ± 14%	Explore
germinal center B cell	3 studies	44% ± 6%	Explore
muscle cell	3 studies	51% ± 18%	Explore
pancreatic ductal cell	3 studies	70% ± 21%	Explore
ependymal cell	3 studies	40% ± 15%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	76% ± 5%	Explore
chondrocyte	3 studies	36% ± 5%	Explore
mucus secreting cell	3 studies	33% ± 10%	Explore
group 3 innate lymphoid cell	3 studies	68% ± 14%	Explore
melanocyte	3 studies	40% ± 16%	Explore
T-helper 1 cell	3 studies	63% ± 4%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	60% ± 7%	Explore
double-positive, alpha-beta thymocyte	3 studies	72% ± 12%	Explore
progenitor cell of mammary luminal epithelium	3 studies	31% ± 10%	Explore
mural cell	3 studies	57% ± 16%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	20 studies	41% ± 14%	Explore
brain	20 studies	42% ± 20%	Explore
peripheral blood	19 studies	52% ± 15%	Explore
intestine	10 studies	34% ± 13%	Explore
eye	10 studies	39% ± 13%	Explore
kidney	9 studies	35% ± 11%	Explore
liver	6 studies	44% ± 17%	Explore
lymph node	5 studies	49% ± 8%	Explore
breast	5 studies	37% ± 14%	Explore
pancreas	4 studies	56% ± 25%	Explore
bone marrow	4 studies	48% ± 19%	Explore
heart	4 studies	31% ± 7%	Explore
uterus	4 studies	54% ± 17%	Explore
prostate	4 studies	35% ± 9%	Explore
adipose	4 studies	40% ± 8%	Explore
placenta	3 studies	69% ± 18%	Explore
skin	3 studies	21% ± 3%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	10699.83	1445 / 1445	100%	104.09	183 / 183
breast	100%	13106.68	459 / 459	100%	78.69	1115 / 1118
bladder	100%	11514.19	21 / 21	100%	51.46	502 / 504
skin	100%	15054.77	1809 / 1809	100%	67.22	470 / 472
uterus	100%	13371.39	170 / 170	100%	52.02	457 / 459
lung	100%	14309.62	578 / 578	99%	65.78	1149 / 1155
ovary	100%	12931.23	180 / 180	99%	45.45	427 / 430
intestine	100%	11015.56	966 / 966	99%	51.59	522 / 527
brain	100%	7528.72	2639 / 2642	99%	39.98	698 / 705
thymus	100%	12018.78	653 / 653	99%	36.61	596 / 605
stomach	100%	8351.32	359 / 359	98%	64.33	281 / 286
prostate	100%	11951.51	245 / 245	98%	38.36	493 / 502
pancreas	100%	6034.61	328 / 328	98%	45.39	174 / 178
kidney	100%	8694.73	89 / 89	94%	38.29	851 / 901
adrenal gland	100%	7631.17	258 / 258	87%	21.43	199 / 230
liver	100%	4507.05	226 / 226	85%	25.13	345 / 406
adipose	100%	12310.24	1204 / 1204	0%	0	0 / 0
blood vessel	100%	11306.13	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	50.19	29 / 29
muscle	100%	5942.21	803 / 803	0%	0	0 / 0
spleen	100%	12622.63	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	18.64	1 / 1
heart	99%	5589.60	849 / 861	0%	0	0 / 0
tonsil	0%	0	0 / 0	98%	59.36	44 / 45
peripheral blood	94%	10015.08	876 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	94%	27.21	75 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0002244	Biological process	hematopoietic progenitor cell differentiation
GO_0034063	Biological process	stress granule assembly
GO_0005829	Cellular component	cytosol
GO_0010494	Cellular component	cytoplasmic stress granule
GO_0016020	Cellular component	membrane
GO_0005515	Molecular function	protein binding
GO_0003723	Molecular function	RNA binding

Gene name	PRRC2C
Protein name	Protein PRRC2C Protein PRRC2C (BAT2 domain-containing protein 1) (HBV X-transactivated gene 2 protein) (HBV XAg-transactivated protein 2) (HLA-B-associated transcript 2-like 2) (Proline-rich and coiled-coil-containing protein 2C) Proline rich coiled-coil 2C
Synonyms	XTP2 KIAA1096 BAT2D1 BAT2L2
Description	FUNCTION: Required for efficient formation of stress granules. .
Accessions	ENST00000338920.8 [Q9Y520-4] H7C5N8 ENST00000498596.5 ENST00000647382.2 [Q9Y520-7] A0A2R8Y424 ENST00000426496.6 [Q9Y520-4] ENST00000644916.1 E7EPN9 ENST00000367742.7 A0A2R8Y7F4 A0A2R8YET2 ENST00000495585.1 ENST00000647382 Q9Y520

PRRC2C report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review