Name | Number of supported studies | Average coverage | |
---|---|---|---|
lung | 18 studies | 78% ± 20% | |
peripheral blood | 17 studies | 87% ± 11% | |
intestine | 12 studies | 92% ± 6% | |
brain | 12 studies | 61% ± 22% | |
kidney | 7 studies | 80% ± 22% | |
liver | 6 studies | 79% ± 13% | |
eye | 6 studies | 73% ± 25% | |
bone marrow | 5 studies | 92% ± 5% | |
lymph node | 4 studies | 88% ± 11% | |
breast | 4 studies | 93% ± 2% | |
placenta | 3 studies | 71% ± 37% | |
heart | 3 studies | 42% ± 15% | |
uterus | 3 studies | 98% ± 1% | |
prostate | 3 studies | 100% ± 0% | |
esophagus | 3 studies | 79% ± 18% | |
skin | 3 studies | 92% ± 4% | |
adipose | 3 studies | 76% ± 11% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
adrenal gland | 100% | 953982.92 | 258 / 258 | 100% | 18983.49 | 230 / 230 |
kidney | 100% | 1385929.07 | 89 / 89 | 99% | 18880.24 | 893 / 901 |
liver | 100% | 860386.99 | 225 / 226 | 100% | 13145.79 | 404 / 406 |
brain | 100% | 1394704.96 | 2640 / 2642 | 98% | 13231.03 | 692 / 705 |
prostate | 100% | 599208.51 | 244 / 245 | 98% | 11647.32 | 493 / 502 |
pancreas | 99% | 369286.50 | 325 / 328 | 98% | 10531.26 | 175 / 178 |
stomach | 100% | 741082.35 | 359 / 359 | 97% | 14749.28 | 278 / 286 |
breast | 100% | 719614.20 | 457 / 459 | 98% | 10834.06 | 1091 / 1118 |
intestine | 100% | 685806.68 | 962 / 966 | 98% | 13156.87 | 514 / 527 |
esophagus | 97% | 521000.15 | 1399 / 1445 | 100% | 13383.44 | 183 / 183 |
bladder | 100% | 476872.52 | 21 / 21 | 97% | 13301.00 | 487 / 504 |
thymus | 96% | 376031.79 | 630 / 653 | 98% | 11320.31 | 592 / 605 |
lung | 94% | 323199.98 | 544 / 578 | 95% | 9869.95 | 1092 / 1155 |
uterus | 90% | 272139.55 | 153 / 170 | 96% | 9098.32 | 441 / 459 |
skin | 85% | 366794.44 | 1540 / 1809 | 97% | 11674.67 | 459 / 472 |
ovary | 81% | 233487.88 | 146 / 180 | 100% | 15152.55 | 429 / 430 |
eye | 0% | 0 | 0 / 0 | 100% | 17388.56 | 80 / 80 |
heart | 100% | 1456622.77 | 861 / 861 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 24493.09 | 1 / 1 |
muscle | 100% | 816879.32 | 802 / 803 | 0% | 0 | 0 / 0 |
adipose | 100% | 758720.95 | 1202 / 1204 | 0% | 0 | 0 / 0 |
spleen | 98% | 303471.91 | 235 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 93% | 5566.10 | 42 / 45 |
blood vessel | 79% | 232294.70 | 1061 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 69% | 4213.14 | 20 / 29 |
peripheral blood | 18% | 39605.85 | 169 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0009060 | Biological process | aerobic respiration |
GO_0001666 | Biological process | response to hypoxia |
GO_0006120 | Biological process | mitochondrial electron transport, NADH to ubiquinone |
GO_0042776 | Biological process | proton motive force-driven mitochondrial ATP synthesis |
GO_0055085 | Biological process | transmembrane transport |
GO_0072593 | Biological process | reactive oxygen species metabolic process |
GO_0032981 | Biological process | mitochondrial respiratory chain complex I assembly |
GO_0045271 | Cellular component | respiratory chain complex I |
GO_0005743 | Cellular component | mitochondrial inner membrane |
GO_0035255 | Molecular function | ionotropic glutamate receptor binding |
GO_0019901 | Molecular function | protein kinase binding |
GO_0008137 | Molecular function | NADH dehydrogenase (ubiquinone) activity |
GO_0005515 | Molecular function | protein binding |
Gene name | MT-ND2 |
Protein name | NADH-ubiquinone oxidoreductase chain 2 (EC 7.1.1.2) (NADH dehydrogenase subunit 2) |
Synonyms | MTND2 ND2 NADH2 |
Description | FUNCTION: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor . Essential for the catalytic activity and assembly of complex I . . |
Accessions | P03891 ENST00000361453.3 |