HMGN2 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
B cell	40 studies	57% ± 19%	Explore
fibroblast	38 studies	55% ± 23%	Explore
natural killer cell	37 studies	55% ± 19%	Explore
CD8-positive, alpha-beta T cell	35 studies	55% ± 22%	Explore
T cell	33 studies	53% ± 24%	Explore
macrophage	33 studies	57% ± 18%	Explore
endothelial cell	32 studies	39% ± 19%	Explore
pericyte	30 studies	53% ± 20%	Explore
conventional dendritic cell	30 studies	64% ± 16%	Explore
CD4-positive, alpha-beta T cell	30 studies	58% ± 21%	Explore
regulatory T cell	28 studies	61% ± 18%	Explore
plasmacytoid dendritic cell	27 studies	67% ± 17%	Explore
dendritic cell	25 studies	54% ± 25%	Explore
classical monocyte	25 studies	52% ± 16%	Explore
smooth muscle cell	24 studies	60% ± 20%	Explore
non-classical monocyte	24 studies	69% ± 16%	Explore
epithelial cell	21 studies	58% ± 24%	Explore
monocyte	20 studies	59% ± 18%	Explore
mature NK T cell	20 studies	47% ± 18%	Explore
memory B cell	20 studies	59% ± 15%	Explore
basal cell	20 studies	46% ± 16%	Explore
mast cell	19 studies	47% ± 17%	Explore
gamma-delta T cell	19 studies	54% ± 19%	Explore
naive B cell	19 studies	59% ± 14%	Explore
endothelial cell of lymphatic vessel	18 studies	45% ± 16%	Explore
connective tissue cell	18 studies	62% ± 24%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	17 studies	51% ± 14%	Explore
ciliated cell	17 studies	65% ± 20%	Explore
plasma cell	16 studies	51% ± 16%	Explore
CD16-positive, CD56-dim natural killer cell, human	16 studies	53% ± 16%	Explore
CD16-negative, CD56-bright natural killer cell, human	15 studies	50% ± 16%	Explore
mucosal invariant T cell	15 studies	46% ± 16%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	14 studies	55% ± 14%	Explore
myofibroblast cell	14 studies	66% ± 24%	Explore
myeloid cell	13 studies	56% ± 20%	Explore
CD4-positive, alpha-beta memory T cell	12 studies	55% ± 19%	Explore
CD8-positive, alpha-beta memory T cell	12 studies	55% ± 20%	Explore
secretory cell	12 studies	48% ± 21%	Explore
effector memory CD8-positive, alpha-beta T cell	11 studies	43% ± 18%	Explore
innate lymphoid cell	11 studies	50% ± 17%	Explore
plasmablast	11 studies	64% ± 23%	Explore
capillary endothelial cell	11 studies	33% ± 16%	Explore
vein endothelial cell	11 studies	41% ± 21%	Explore
progenitor cell	10 studies	69% ± 27%	Explore
goblet cell	10 studies	51% ± 20%	Explore
mesothelial cell	10 studies	67% ± 31%	Explore
endothelial cell of vascular tree	10 studies	39% ± 12%	Explore
effector CD8-positive, alpha-beta T cell	9 studies	62% ± 22%	Explore
leukocyte	9 studies	53% ± 24%	Explore
neutrophil	9 studies	47% ± 25%	Explore
abnormal cell	9 studies	67% ± 16%	Explore
endothelial cell of artery	9 studies	34% ± 12%	Explore
retinal rod cell	9 studies	48% ± 25%	Explore
type I pneumocyte	8 studies	48% ± 21%	Explore
type II pneumocyte	8 studies	55% ± 21%	Explore
T follicular helper cell	8 studies	63% ± 9%	Explore
transit amplifying cell	8 studies	50% ± 30%	Explore
club cell	7 studies	55% ± 17%	Explore
platelet	7 studies	28% ± 9%	Explore
hematopoietic stem cell	7 studies	72% ± 17%	Explore
precursor B cell	7 studies	72% ± 15%	Explore
neuron	7 studies	49% ± 23%	Explore
alveolar macrophage	6 studies	61% ± 19%	Explore
hematopoietic precursor cell	6 studies	62% ± 23%	Explore
effector CD4-positive, alpha-beta T cell	6 studies	63% ± 20%	Explore
epithelial cell of proximal tubule	6 studies	47% ± 20%	Explore
renal alpha-intercalated cell	6 studies	54% ± 19%	Explore
retinal cone cell	6 studies	57% ± 30%	Explore
immature B cell	6 studies	72% ± 19%	Explore
astrocyte	6 studies	35% ± 16%	Explore
erythrocyte	6 studies	58% ± 27%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	58% ± 18%	Explore
CD4-positive helper T cell	5 studies	34% ± 11%	Explore
CD4-positive, alpha-beta cytotoxic T cell	5 studies	52% ± 25%	Explore
central memory CD8-positive, alpha-beta T cell	5 studies	42% ± 18%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	5 studies	49% ± 14%	Explore
exhausted T cell	5 studies	63% ± 15%	Explore
ionocyte	5 studies	51% ± 9%	Explore
respiratory goblet cell	5 studies	39% ± 26%	Explore
mononuclear phagocyte	5 studies	57% ± 16%	Explore
kidney loop of Henle epithelial cell	5 studies	48% ± 7%	Explore
enterocyte	5 studies	38% ± 15%	Explore
enteroendocrine cell	5 studies	78% ± 15%	Explore
erythroblast	5 studies	61% ± 26%	Explore
intestinal crypt stem cell	5 studies	56% ± 23%	Explore
IgG plasma cell	5 studies	28% ± 12%	Explore
amacrine cell	5 studies	48% ± 22%	Explore
pro-B cell	5 studies	72% ± 17%	Explore
T-helper 17 cell	5 studies	63% ± 22%	Explore
group 3 innate lymphoid cell	5 studies	69% ± 12%	Explore
double negative thymocyte	5 studies	68% ± 15%	Explore
intermediate monocyte	5 studies	70% ± 12%	Explore
granulocyte	5 studies	50% ± 17%	Explore
oligodendrocyte precursor cell	5 studies	45% ± 24%	Explore
interneuron	5 studies	41% ± 22%	Explore
deuterosomal cell	4 studies	67% ± 21%	Explore
precursor cell	4 studies	59% ± 29%	Explore
pancreatic A cell	4 studies	87% ± 5%	Explore
type B pancreatic cell	4 studies	78% ± 5%	Explore
monocyte-derived dendritic cell	4 studies	56% ± 21%	Explore
podocyte	4 studies	78% ± 16%	Explore
kidney distal convoluted tubule epithelial cell	4 studies	72% ± 24%	Explore
IgA plasma cell	4 studies	31% ± 10%	Explore
brush cell	4 studies	43% ± 13%	Explore
retina horizontal cell	4 studies	45% ± 19%	Explore
retinal pigment epithelial cell	4 studies	43% ± 25%	Explore
adventitial cell	4 studies	46% ± 16%	Explore
mucus secreting cell	4 studies	30% ± 8%	Explore
Mueller cell	4 studies	41% ± 15%	Explore
acinar cell	4 studies	42% ± 16%	Explore
muscle cell	4 studies	38% ± 18%	Explore
germinal center B cell	4 studies	81% ± 6%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	69% ± 15%	Explore
luminal cell of prostate epithelium	4 studies	42% ± 17%	Explore
GABAergic neuron	4 studies	23% ± 10%	Explore
glutamatergic neuron	4 studies	25% ± 7%	Explore
glial cell	4 studies	48% ± 25%	Explore
hepatocyte	4 studies	36% ± 28%	Explore
T-helper 1 cell	4 studies	68% ± 11%	Explore
duct epithelial cell	3 studies	39% ± 0%	Explore
pancreatic D cell	3 studies	86% ± 7%	Explore
glomerular endothelial cell	3 studies	24% ± 7%	Explore
neural crest cell	3 studies	90% ± 7%	Explore
retinal bipolar neuron	3 studies	63% ± 24%	Explore
OFF-bipolar cell	3 studies	42% ± 12%	Explore
ON-bipolar cell	3 studies	36% ± 10%	Explore
GABAergic amacrine cell	3 studies	29% ± 11%	Explore
glycinergic amacrine cell	3 studies	41% ± 9%	Explore
renal principal cell	3 studies	52% ± 16%	Explore
extravillous trophoblast	3 studies	40% ± 22%	Explore
placental villous trophoblast	3 studies	88% ± 7%	Explore
lymphocyte	3 studies	62% ± 27%	Explore
megakaryocyte	3 studies	31% ± 12%	Explore
neuroendocrine cell	3 studies	66% ± 22%	Explore
microglial cell	3 studies	37% ± 14%	Explore
serous secreting cell	3 studies	53% ± 11%	Explore
intraepithelial lymphocyte	3 studies	60% ± 21%	Explore
rod bipolar cell	3 studies	41% ± 14%	Explore
myoepithelial cell	3 studies	69% ± 14%	Explore
inflammatory macrophage	3 studies	40% ± 12%	Explore
pancreatic ductal cell	3 studies	79% ± 7%	Explore
neural progenitor cell	3 studies	36% ± 21%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	73% ± 18%	Explore
keratinocyte	3 studies	37% ± 5%	Explore
oligodendrocyte	3 studies	26% ± 7%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	62% ± 13%	Explore
double-positive, alpha-beta thymocyte	3 studies	81% ± 10%	Explore
progenitor cell of mammary luminal epithelium	3 studies	52% ± 10%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	19 studies	58% ± 10%	Explore
lung	17 studies	53% ± 15%	Explore
intestine	13 studies	48% ± 23%	Explore
eye	11 studies	41% ± 22%	Explore
kidney	9 studies	47% ± 21%	Explore
brain	9 studies	30% ± 11%	Explore
lymph node	7 studies	56% ± 22%	Explore
liver	7 studies	45% ± 23%	Explore
bone marrow	5 studies	41% ± 16%	Explore
uterus	5 studies	57% ± 13%	Explore
pancreas	4 studies	76% ± 9%	Explore
prostate	4 studies	31% ± 11%	Explore
breast	4 studies	49% ± 7%	Explore
placenta	3 studies	59% ± 22%	Explore
ovary	3 studies	49% ± 9%	Explore
skin	3 studies	33% ± 9%	Explore
thymus	3 studies	70% ± 34%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	7442.00	1445 / 1445	100%	142.14	183 / 183
lung	100%	9087.18	578 / 578	100%	189.34	1155 / 1155
ovary	100%	12402.69	180 / 180	100%	229.11	430 / 430
stomach	100%	5669.07	359 / 359	100%	154.83	286 / 286
thymus	100%	10833.66	653 / 653	100%	324.44	604 / 605
prostate	100%	9236.96	245 / 245	100%	219.53	501 / 502
uterus	100%	10498.84	170 / 170	100%	376.10	458 / 459
intestine	100%	8559.94	966 / 966	99%	175.61	524 / 527
skin	100%	9510.19	1809 / 1809	99%	195.88	469 / 472
brain	99%	4880.11	2628 / 2642	100%	193.43	704 / 705
breast	100%	8423.90	459 / 459	99%	239.81	1110 / 1118
bladder	100%	7634.71	21 / 21	99%	231.61	500 / 504
pancreas	100%	4635.08	327 / 328	99%	147.00	176 / 178
adrenal gland	100%	7120.67	258 / 258	94%	126.35	216 / 230
kidney	100%	6600.06	89 / 89	94%	120.83	843 / 901
liver	99%	3174.38	223 / 226	93%	101.70	378 / 406
lymph node	0%	0	0 / 0	100%	314.04	29 / 29
spleen	100%	10198.67	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	371.90	45 / 45
ureter	0%	0	0 / 0	100%	72.25	1 / 1
blood vessel	100%	8446.37	1334 / 1335	0%	0	0 / 0
adipose	100%	7355.99	1203 / 1204	0%	0	0 / 0
peripheral blood	100%	10894.48	925 / 929	0%	0	0 / 0
muscle	98%	4580.40	788 / 803	0%	0	0 / 0
heart	95%	3715.13	818 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	91%	78.48	73 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0006325	Biological process	chromatin organization
GO_0061844	Biological process	antimicrobial humoral immune response mediated by antimicrobial peptide
GO_0031640	Biological process	killing of cells of another organism
GO_0005615	Cellular component	extracellular space
GO_0000785	Cellular component	chromatin
GO_0005737	Cellular component	cytoplasm
GO_0005634	Cellular component	nucleus
GO_0031492	Molecular function	nucleosomal DNA binding
GO_0005515	Molecular function	protein binding
GO_0003682	Molecular function	chromatin binding
GO_0003723	Molecular function	RNA binding

Gene name	HMGN2
Protein name	Non-histone chromosomal protein HMG-17 (High mobility group nucleosome-binding domain-containing protein 2)
Synonyms	HMG17
Description	FUNCTION: Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in a unique chromatin conformation (By similarity). .
Accessions	ENST00000361427.6 P05204

HMGN2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review