PTMA | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
B cell	53 studies	90% ± 20%	Explore
endothelial cell	53 studies	76% ± 27%	Explore
macrophage	49 studies	82% ± 24%	Explore
natural killer cell	49 studies	91% ± 18%	Explore
fibroblast	46 studies	82% ± 26%	Explore
T cell	44 studies	84% ± 23%	Explore
CD8-positive, alpha-beta T cell	41 studies	91% ± 16%	Explore
pericyte	40 studies	83% ± 27%	Explore
CD4-positive, alpha-beta T cell	36 studies	92% ± 13%	Explore
smooth muscle cell	33 studies	79% ± 29%	Explore
conventional dendritic cell	33 studies	97% ± 6%	Explore
plasmacytoid dendritic cell	32 studies	96% ± 9%	Explore
dendritic cell	31 studies	87% ± 20%	Explore
plasma cell	30 studies	80% ± 24%	Explore
mast cell	29 studies	86% ± 24%	Explore
endothelial cell of lymphatic vessel	29 studies	83% ± 25%	Explore
regulatory T cell	29 studies	97% ± 7%	Explore
classical monocyte	28 studies	91% ± 14%	Explore
monocyte	27 studies	84% ± 20%	Explore
non-classical monocyte	27 studies	94% ± 12%	Explore
epithelial cell	26 studies	85% ± 22%	Explore
mature NK T cell	25 studies	89% ± 18%	Explore
basal cell	24 studies	83% ± 25%	Explore
gamma-delta T cell	22 studies	93% ± 13%	Explore
memory B cell	21 studies	98% ± 4%	Explore
connective tissue cell	20 studies	86% ± 24%	Explore
astrocyte	20 studies	44% ± 25%	Explore
ciliated cell	19 studies	83% ± 22%	Explore
naive B cell	19 studies	97% ± 4%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	19 studies	93% ± 14%	Explore
microglial cell	19 studies	54% ± 31%	Explore
mucosal invariant T cell	17 studies	95% ± 9%	Explore
endothelial cell of artery	17 studies	88% ± 17%	Explore
capillary endothelial cell	17 studies	86% ± 16%	Explore
CD16-negative, CD56-bright natural killer cell, human	16 studies	90% ± 18%	Explore
CD16-positive, CD56-dim natural killer cell, human	16 studies	92% ± 14%	Explore
oligodendrocyte	16 studies	57% ± 19%	Explore
myofibroblast cell	16 studies	87% ± 24%	Explore
vein endothelial cell	16 studies	85% ± 21%	Explore
myeloid cell	16 studies	76% ± 29%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	15 studies	93% ± 16%	Explore
mesothelial cell	15 studies	78% ± 28%	Explore
endothelial cell of vascular tree	15 studies	87% ± 24%	Explore
innate lymphoid cell	14 studies	97% ± 3%	Explore
neutrophil	14 studies	60% ± 29%	Explore
CD4-positive, alpha-beta memory T cell	13 studies	91% ± 15%	Explore
CD8-positive, alpha-beta memory T cell	13 studies	91% ± 18%	Explore
erythrocyte	13 studies	66% ± 23%	Explore
oligodendrocyte precursor cell	13 studies	44% ± 26%	Explore
effector memory CD8-positive, alpha-beta T cell	12 studies	85% ± 20%	Explore
plasmablast	12 studies	96% ± 4%	Explore
secretory cell	12 studies	93% ± 11%	Explore
leukocyte	12 studies	87% ± 19%	Explore
progenitor cell	12 studies	82% ± 27%	Explore
goblet cell	12 studies	82% ± 19%	Explore
type I pneumocyte	11 studies	72% ± 25%	Explore
platelet	11 studies	77% ± 22%	Explore
club cell	11 studies	80% ± 29%	Explore
glutamatergic neuron	11 studies	46% ± 19%	Explore
type II pneumocyte	10 studies	80% ± 27%	Explore
T follicular helper cell	10 studies	98% ± 2%	Explore
GABAergic neuron	10 studies	41% ± 20%	Explore
neuron	10 studies	71% ± 23%	Explore
IgG plasma cell	10 studies	78% ± 20%	Explore
effector CD8-positive, alpha-beta T cell	9 studies	97% ± 6%	Explore
abnormal cell	9 studies	93% ± 9%	Explore
IgA plasma cell	9 studies	75% ± 25%	Explore
hematopoietic stem cell	9 studies	99% ± 2%	Explore
respiratory goblet cell	8 studies	79% ± 24%	Explore
mononuclear phagocyte	8 studies	79% ± 28%	Explore
enterocyte	8 studies	74% ± 23%	Explore
retinal rod cell	8 studies	66% ± 26%	Explore
brush cell	8 studies	79% ± 24%	Explore
alveolar macrophage	7 studies	80% ± 23%	Explore
ionocyte	7 studies	91% ± 14%	Explore
effector CD4-positive, alpha-beta T cell	7 studies	97% ± 4%	Explore
epithelial cell of proximal tubule	7 studies	71% ± 25%	Explore
enteroendocrine cell	7 studies	89% ± 14%	Explore
transit amplifying cell	7 studies	81% ± 23%	Explore
amacrine cell	7 studies	68% ± 22%	Explore
glial cell	7 studies	71% ± 31%	Explore
interneuron	7 studies	57% ± 24%	Explore
retinal cone cell	7 studies	68% ± 31%	Explore
precursor B cell	7 studies	92% ± 20%	Explore
immature B cell	7 studies	88% ± 29%	Explore
CD4-positive helper T cell	6 studies	97% ± 4%	Explore
CD4-positive, alpha-beta cytotoxic T cell	6 studies	88% ± 16%	Explore
kidney loop of Henle epithelial cell	6 studies	85% ± 24%	Explore
renal alpha-intercalated cell	6 studies	94% ± 6%	Explore
erythroblast	6 studies	76% ± 27%	Explore
intestinal crypt stem cell	6 studies	75% ± 34%	Explore
retina horizontal cell	6 studies	79% ± 14%	Explore
retinal ganglion cell	6 studies	57% ± 24%	Explore
lymphocyte	6 studies	76% ± 34%	Explore
mucus secreting cell	6 studies	55% ± 28%	Explore
adipocyte	6 studies	26% ± 3%	Explore
intermediate monocyte	6 studies	94% ± 9%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	99% ± 2%	Explore
melanocyte	6 studies	84% ± 22%	Explore
central memory CD8-positive, alpha-beta T cell	5 studies	96% ± 3%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	5 studies	95% ± 4%	Explore
hematopoietic precursor cell	5 studies	93% ± 5%	Explore
exhausted T cell	5 studies	86% ± 26%	Explore
kidney distal convoluted tubule epithelial cell	5 studies	97% ± 4%	Explore
megakaryocyte	5 studies	98% ± 2%	Explore
OFF-bipolar cell	5 studies	61% ± 17%	Explore
ON-bipolar cell	5 studies	54% ± 19%	Explore
pro-B cell	5 studies	87% ± 25%	Explore
neuroendocrine cell	5 studies	95% ± 8%	Explore
T-helper 17 cell	5 studies	100% ± 1%	Explore
chondrocyte	5 studies	60% ± 31%	Explore
group 3 innate lymphoid cell	5 studies	99% ± 1%	Explore
Mueller cell	5 studies	74% ± 22%	Explore
inflammatory macrophage	5 studies	79% ± 15%	Explore
double negative thymocyte	5 studies	99% ± 1%	Explore
hepatocyte	5 studies	58% ± 22%	Explore
granulocyte	5 studies	95% ± 7%	Explore
deuterosomal cell	4 studies	87% ± 16%	Explore
duct epithelial cell	4 studies	97% ± 1%	Explore
precursor cell	4 studies	91% ± 13%	Explore
pancreatic A cell	4 studies	91% ± 8%	Explore
type B pancreatic cell	4 studies	89% ± 12%	Explore
monocyte-derived dendritic cell	4 studies	97% ± 5%	Explore
cholangiocyte	4 studies	42% ± 32%	Explore
endothelial cell of sinusoid	4 studies	51% ± 27%	Explore
glomerular endothelial cell	4 studies	91% ± 6%	Explore
kidney connecting tubule epithelial cell	4 studies	96% ± 3%	Explore
podocyte	4 studies	97% ± 2%	Explore
retinal bipolar neuron	4 studies	72% ± 23%	Explore
GABAergic amacrine cell	4 studies	70% ± 15%	Explore
glycinergic amacrine cell	4 studies	70% ± 20%	Explore
Schwann cell	4 studies	82% ± 31%	Explore
retinal pigment epithelial cell	4 studies	76% ± 24%	Explore
adventitial cell	4 studies	85% ± 13%	Explore
acinar cell	4 studies	78% ± 28%	Explore
muscle cell	4 studies	57% ± 25%	Explore
germinal center B cell	4 studies	99% ± 0%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	97% ± 5%	Explore
luminal cell of prostate epithelium	4 studies	79% ± 32%	Explore
IgM plasma cell	4 studies	86% ± 15%	Explore
keratinocyte	4 studies	98% ± 3%	Explore
T-helper 1 cell	4 studies	100% ± 0%	Explore
Langerhans cell	3 studies	95% ± 5%	Explore
hillock cell	3 studies	76% ± 31%	Explore
squamous epithelial cell	3 studies	63% ± 27%	Explore
pancreatic D cell	3 studies	94% ± 7%	Explore
renal beta-intercalated cell	3 studies	98% ± 2%	Explore
neural crest cell	3 studies	100% ± 0%	Explore
paneth cell	3 studies	91% ± 9%	Explore
GABAergic interneuron	3 studies	32% ± 14%	Explore
granule cell	3 studies	36% ± 20%	Explore
renal principal cell	3 studies	96% ± 3%	Explore
thymocyte	3 studies	99% ± 1%	Explore
extravillous trophoblast	3 studies	99% ± 1%	Explore
placental villous trophoblast	3 studies	96% ± 4%	Explore
serous secreting cell	3 studies	67% ± 10%	Explore
tissue-resident macrophage	3 studies	79% ± 27%	Explore
follicular B cell	3 studies	97% ± 2%	Explore
intraepithelial lymphocyte	3 studies	99% ± 1%	Explore
rod bipolar cell	3 studies	76% ± 18%	Explore
myoepithelial cell	3 studies	100% ± 0%	Explore
pancreatic ductal cell	3 studies	97% ± 1%	Explore
neural progenitor cell	3 studies	48% ± 21%	Explore
ependymal cell	3 studies	50% ± 23%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	100% ± 0%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	99% ± 1%	Explore
double-positive, alpha-beta thymocyte	3 studies	99% ± 1%	Explore
progenitor cell of mammary luminal epithelium	3 studies	99% ± 1%	Explore
mural cell	3 studies	66% ± 13%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	22 studies	92% ± 14%	Explore
lung	21 studies	82% ± 22%	Explore
brain	20 studies	52% ± 21%	Explore
intestine	15 studies	78% ± 28%	Explore
eye	11 studies	71% ± 22%	Explore
liver	9 studies	65% ± 28%	Explore
kidney	9 studies	81% ± 22%	Explore
lymph node	7 studies	94% ± 10%	Explore
bone marrow	6 studies	82% ± 21%	Explore
heart	6 studies	35% ± 17%	Explore
uterus	6 studies	80% ± 28%	Explore
pancreas	5 studies	83% ± 21%	Explore
prostate	5 studies	70% ± 36%	Explore
placenta	4 studies	86% ± 20%	Explore
adipose	4 studies	50% ± 26%	Explore
esophagus	4 studies	63% ± 29%	Explore
skin	4 studies	81% ± 28%	Explore
breast	4 studies	96% ± 4%	Explore
ovary	3 studies	76% ± 31%	Explore
adrenal gland	3 studies	84% ± 16%	Explore
stomach	3 studies	66% ± 21%	Explore
thymus	3 studies	79% ± 30%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
intestine	100%	40087.91	966 / 966	100%	1048.94	527 / 527
ovary	100%	41507.37	180 / 180	100%	1225.39	430 / 430
stomach	100%	27188.28	359 / 359	100%	983.30	286 / 286
esophagus	100%	33783.56	1444 / 1445	100%	805.30	183 / 183
breast	100%	42062.50	459 / 459	100%	724.05	1116 / 1118
thymus	100%	42123.43	653 / 653	100%	900.89	603 / 605
lung	100%	37337.65	576 / 578	100%	745.40	1155 / 1155
bladder	100%	35209.57	21 / 21	100%	791.19	502 / 504
prostate	100%	28510.75	245 / 245	100%	496.55	500 / 502
uterus	100%	44981.83	170 / 170	100%	954.30	457 / 459
pancreas	100%	24231.76	327 / 328	99%	618.39	176 / 178
skin	100%	47887.42	1809 / 1809	99%	502.72	465 / 472
brain	100%	21277.62	2630 / 2642	99%	343.76	695 / 705
kidney	100%	32235.09	89 / 89	96%	468.77	867 / 901
adrenal gland	100%	19208.89	258 / 258	88%	249.23	202 / 230
liver	92%	12670.58	207 / 226	93%	298.85	377 / 406
adipose	100%	45545.32	1204 / 1204	0%	0	0 / 0
blood vessel	100%	50764.73	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	880.69	29 / 29
spleen	100%	33529.24	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	1049.40	45 / 45
ureter	0%	0	0 / 0	100%	583.08	1 / 1
eye	0%	0	0 / 0	96%	422.15	77 / 80
heart	87%	11957.21	745 / 861	0%	0	0 / 0
peripheral blood	84%	34661.65	777 / 929	0%	0	0 / 0
muscle	53%	5129.23	425 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

IV. Literature review

[source]

Gene name	PTMA
Protein name	Prothymosin alpha Prothymosin alpha [Cleaved into: Prothymosin alpha, N-terminally processed; Thymosin alpha-1]
Synonyms	TMSA PTMAP7
Description	FUNCTION: Prothymosin alpha may mediate immune function by conferring resistance to certain opportunistic infections. FUNCTION: Prothymosin alpha may mediate immune function by conferring resistance to certain opportunistic infections. . FUNCTION: Prothymosin alpha may mediate immune function by conferring resistance to certain opportunistic infections. . FUNCTION: Prothymosin alpha may mediate immune function by conferring resistance to certain opportunistic infections. . FUNCTION: Prothymosin alpha may mediate immune function by conferring resistance to certain opportunistic infections. . FUNCTION: Prothymosin alpha may mediate immune function by conferring resistance to certain opportunistic infections. . FUNCTION: Prothymosin alpha may mediate immune function by conferring resistance to certain opportunistic infections. . FUNCTION: Prothymosin alpha may mediate immune function by conferring resistance to certain opportunistic infections. . FUNCTION: Prothymosin alpha may mediate immune function by conferring resistance to certain opportunistic infections. .
Accessions	ENST00000409683.5 B8ZZA1 P06454 B8ZZQ6 ENST00000409321.5 Q8TBK9 H7C031 F8WCE8 Q7KZ52 Q53S24 Q9NYD3 ENST00000410064.5 ENST00000409115.8 [P06454-2] B8ZZW7 H7C2N1 ENST00000440384.1 Q15254 ENST00000341369.11 [P06454-1] ENST00000448874.5 ENST00000412128.1

GO_0006351	Biological process	DNA-templated transcription
GO_0043066	Biological process	negative regulation of apoptotic process
GO_0045944	Biological process	positive regulation of transcription by RNA polymerase II
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0005634	Cellular component	nucleus
GO_0140297	Molecular function	DNA-binding transcription factor binding
GO_0005515	Molecular function	protein binding
GO_0042393	Molecular function	histone binding

PTMA report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review