PRELID1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	38 studies	46% ± 14%	Explore
B cell	33 studies	34% ± 12%	Explore
CD8-positive, alpha-beta T cell	33 studies	41% ± 19%	Explore
macrophage	31 studies	45% ± 16%	Explore
fibroblast	30 studies	35% ± 12%	Explore
endothelial cell	29 studies	38% ± 14%	Explore
CD4-positive, alpha-beta T cell	28 studies	37% ± 18%	Explore
T cell	27 studies	38% ± 13%	Explore
conventional dendritic cell	27 studies	62% ± 18%	Explore
classical monocyte	25 studies	63% ± 14%	Explore
smooth muscle cell	24 studies	31% ± 10%	Explore
non-classical monocyte	23 studies	80% ± 14%	Explore
pericyte	23 studies	33% ± 10%	Explore
regulatory T cell	23 studies	39% ± 16%	Explore
plasma cell	21 studies	49% ± 19%	Explore
monocyte	20 studies	60% ± 18%	Explore
plasmacytoid dendritic cell	20 studies	43% ± 13%	Explore
epithelial cell	20 studies	52% ± 21%	Explore
memory B cell	19 studies	35% ± 9%	Explore
mature NK T cell	18 studies	40% ± 12%	Explore
basal cell	18 studies	45% ± 18%	Explore
endothelial cell of lymphatic vessel	17 studies	51% ± 14%	Explore
gamma-delta T cell	17 studies	40% ± 12%	Explore
dendritic cell	16 studies	59% ± 24%	Explore
naive B cell	16 studies	29% ± 7%	Explore
connective tissue cell	16 studies	36% ± 10%	Explore
CD16-positive, CD56-dim natural killer cell, human	15 studies	46% ± 13%	Explore
CD16-negative, CD56-bright natural killer cell, human	14 studies	44% ± 13%	Explore
mast cell	13 studies	27% ± 6%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	13 studies	30% ± 6%	Explore
plasmablast	12 studies	61% ± 19%	Explore
capillary endothelial cell	12 studies	29% ± 11%	Explore
myofibroblast cell	12 studies	34% ± 9%	Explore
mucosal invariant T cell	12 studies	31% ± 6%	Explore
myeloid cell	12 studies	48% ± 16%	Explore
CD8-positive, alpha-beta memory T cell	11 studies	38% ± 17%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	11 studies	39% ± 13%	Explore
endothelial cell of artery	11 studies	35% ± 13%	Explore
vein endothelial cell	11 studies	35% ± 12%	Explore
endothelial cell of vascular tree	11 studies	35% ± 9%	Explore
CD4-positive, alpha-beta memory T cell	10 studies	39% ± 19%	Explore
ciliated cell	10 studies	39% ± 17%	Explore
secretory cell	10 studies	42% ± 16%	Explore
effector memory CD8-positive, alpha-beta T cell	9 studies	37% ± 11%	Explore
progenitor cell	9 studies	55% ± 16%	Explore
abnormal cell	9 studies	47% ± 17%	Explore
innate lymphoid cell	8 studies	37% ± 11%	Explore
leukocyte	8 studies	39% ± 14%	Explore
T follicular helper cell	8 studies	36% ± 9%	Explore
type I pneumocyte	7 studies	28% ± 12%	Explore
effector CD8-positive, alpha-beta T cell	7 studies	49% ± 23%	Explore
enterocyte	7 studies	60% ± 19%	Explore
goblet cell	7 studies	42% ± 16%	Explore
erythrocyte	7 studies	36% ± 25%	Explore
club cell	6 studies	39% ± 6%	Explore
neutrophil	6 studies	34% ± 9%	Explore
epithelial cell of proximal tubule	6 studies	50% ± 7%	Explore
IgA plasma cell	6 studies	38% ± 12%	Explore
IgG plasma cell	6 studies	37% ± 14%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	42% ± 21%	Explore
alveolar macrophage	5 studies	41% ± 8%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	5 studies	32% ± 8%	Explore
hematopoietic precursor cell	5 studies	52% ± 25%	Explore
exhausted T cell	5 studies	56% ± 17%	Explore
ionocyte	5 studies	31% ± 10%	Explore
respiratory goblet cell	5 studies	37% ± 21%	Explore
mononuclear phagocyte	5 studies	61% ± 18%	Explore
kidney loop of Henle epithelial cell	5 studies	25% ± 5%	Explore
mesothelial cell	5 studies	43% ± 15%	Explore
transit amplifying cell	5 studies	52% ± 22%	Explore
erythroblast	5 studies	44% ± 18%	Explore
neuron	5 studies	39% ± 18%	Explore
type II pneumocyte	5 studies	37% ± 13%	Explore
effector CD4-positive, alpha-beta T cell	5 studies	50% ± 26%	Explore
intermediate monocyte	5 studies	79% ± 17%	Explore
enteroendocrine cell	4 studies	57% ± 13%	Explore
intestinal crypt stem cell	4 studies	50% ± 19%	Explore
retinal ganglion cell	4 studies	58% ± 27%	Explore
adventitial cell	4 studies	26% ± 6%	Explore
CD4-positive helper T cell	4 studies	26% ± 5%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	55% ± 3%	Explore
granulocyte	4 studies	29% ± 10%	Explore
T-helper 17 cell	4 studies	50% ± 25%	Explore
CD4-positive, alpha-beta cytotoxic T cell	3 studies	47% ± 28%	Explore
deuterosomal cell	3 studies	28% ± 9%	Explore
duct epithelial cell	3 studies	43% ± 1%	Explore
precursor cell	3 studies	60% ± 7%	Explore
pancreatic A cell	3 studies	66% ± 20%	Explore
type B pancreatic cell	3 studies	54% ± 21%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	43% ± 8%	Explore
renal alpha-intercalated cell	3 studies	33% ± 5%	Explore
neural crest cell	3 studies	48% ± 3%	Explore
extravillous trophoblast	3 studies	64% ± 13%	Explore
placental villous trophoblast	3 studies	86% ± 6%	Explore
hematopoietic stem cell	3 studies	42% ± 10%	Explore
lymphocyte	3 studies	56% ± 7%	Explore
megakaryocyte	3 studies	33% ± 13%	Explore
precursor B cell	3 studies	44% ± 18%	Explore
pro-B cell	3 studies	22% ± 1%	Explore
brush cell	3 studies	27% ± 14%	Explore
neuroendocrine cell	3 studies	40% ± 11%	Explore
immature B cell	3 studies	36% ± 6%	Explore
amacrine cell	3 studies	38% ± 16%	Explore
retina horizontal cell	3 studies	32% ± 15%	Explore
retinal cone cell	3 studies	51% ± 17%	Explore
retinal rod cell	3 studies	27% ± 9%	Explore
microglial cell	3 studies	36% ± 16%	Explore
mucus secreting cell	3 studies	44% ± 7%	Explore
serous secreting cell	3 studies	54% ± 13%	Explore
intraepithelial lymphocyte	3 studies	45% ± 5%	Explore
germinal center B cell	3 studies	52% ± 1%	Explore
myoepithelial cell	3 studies	38% ± 3%	Explore
inflammatory macrophage	3 studies	40% ± 15%	Explore
luminal cell of prostate epithelium	3 studies	49% ± 10%	Explore
IgM plasma cell	3 studies	40% ± 9%	Explore
oligodendrocyte precursor cell	3 studies	29% ± 11%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	51% ± 21%	Explore
glial cell	3 studies	40% ± 21%	Explore
hepatocyte	3 studies	45% ± 30%	Explore
group 3 innate lymphoid cell	3 studies	40% ± 15%	Explore
keratinocyte	3 studies	46% ± 10%	Explore
T-helper 1 cell	3 studies	53% ± 23%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	26% ± 8%	Explore
central memory CD8-positive, alpha-beta T cell	3 studies	28% ± 8%	Explore
double negative thymocyte	3 studies	44% ± 13%	Explore
progenitor cell of mammary luminal epithelium	3 studies	61% ± 9%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	19 studies	43% ± 12%	Explore
lung	17 studies	39% ± 12%	Explore
intestine	11 studies	41% ± 16%	Explore
kidney	7 studies	42% ± 7%	Explore
liver	7 studies	36% ± 19%	Explore
lymph node	6 studies	38% ± 16%	Explore
eye	5 studies	28% ± 13%	Explore
brain	5 studies	25% ± 5%	Explore
bone marrow	4 studies	32% ± 15%	Explore
uterus	4 studies	42% ± 17%	Explore
breast	4 studies	46% ± 5%	Explore
pancreas	3 studies	63% ± 18%	Explore
placenta	3 studies	67% ± 15%	Explore
prostate	3 studies	43% ± 12%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	1892.21	1445 / 1445	100%	75.11	183 / 183
ovary	100%	1209.18	180 / 180	100%	116.68	430 / 430
stomach	100%	1594.61	359 / 359	100%	98.47	286 / 286
intestine	100%	2112.40	966 / 966	100%	103.61	526 / 527
skin	100%	2496.10	1809 / 1809	100%	54.96	470 / 472
uterus	100%	1367.57	170 / 170	100%	42.01	457 / 459
pancreas	100%	2864.25	328 / 328	99%	39.33	177 / 178
lung	100%	1684.31	576 / 578	100%	40.21	1151 / 1155
liver	100%	1948.82	226 / 226	99%	37.93	403 / 406
breast	100%	1722.90	459 / 459	99%	39.82	1106 / 1118
thymus	100%	1379.80	652 / 653	99%	27.77	599 / 605
bladder	100%	1622.10	21 / 21	99%	60.22	498 / 504
prostate	100%	1436.51	245 / 245	99%	34.74	496 / 502
kidney	100%	2426.22	89 / 89	99%	43.18	890 / 901
brain	99%	988.77	2610 / 2642	100%	34.19	702 / 705
adrenal gland	100%	2002.76	258 / 258	95%	27.73	219 / 230
adipose	100%	1697.36	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	40.24	80 / 80
lymph node	0%	0	0 / 0	100%	77.36	29 / 29
spleen	100%	2551.59	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	43.59	45 / 45
ureter	0%	0	0 / 0	100%	15.50	1 / 1
blood vessel	100%	1447.32	1330 / 1335	0%	0	0 / 0
peripheral blood	99%	3887.39	924 / 929	0%	0	0 / 0
heart	95%	799.58	816 / 861	0%	0	0 / 0
muscle	56%	320.22	447 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0097035	Biological process	regulation of membrane lipid distribution
GO_0045580	Biological process	regulation of T cell differentiation
GO_0015914	Biological process	phospholipid transport
GO_0090201	Biological process	negative regulation of release of cytochrome c from mitochondria
GO_0120009	Biological process	intermembrane lipid transfer
GO_0051881	Biological process	regulation of mitochondrial membrane potential
GO_2001140	Biological process	positive regulation of phospholipid transport
GO_0043066	Biological process	negative regulation of apoptotic process
GO_0070234	Biological process	positive regulation of T cell apoptotic process
GO_0010917	Biological process	negative regulation of mitochondrial membrane potential
GO_0006915	Biological process	apoptotic process
GO_0010950	Biological process	positive regulation of endopeptidase activity
GO_1901857	Biological process	positive regulation of cellular respiration
GO_0005739	Cellular component	mitochondrion
GO_0005758	Cellular component	mitochondrial intermembrane space
GO_0032991	Cellular component	protein-containing complex
GO_0005654	Cellular component	nucleoplasm
GO_1990050	Molecular function	phosphatidic acid transfer activity
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	PRELID1
Protein name	PRELI domain containing 1 (Px19-like protein, isoform CRA_a) PRELI domain-containing protein 1, mitochondrial (25 kDa protein of relevant evolutionary and lymphoid interest) (Px19-like protein) PRELI domain containing 1
Synonyms	CGI-106 SBBI12 PRELI PX19 hCG_1771748
Description	FUNCTION: Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin (CL) in mitochondrial membranes. In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid (PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane. Regulates the mitochondrial apoptotic pathway in primary Th cells. Regulates Th cell differentiation by down-regulating STAT6 thereby reducing IL-4-induced Th2 cell number. May be important for the development of vital and immunocompetent organs. .
Accessions	ENST00000303204.9 [Q9Y255-1] ENST00000503853.1 ENST00000504594.5 ENST00000503216.5 [Q9Y255-2] D6REW1 Q9Y255 D6RC47 H0YA79 ENST00000510797.1

PRELID1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review