MT-ND4 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
B cell	50 studies	90% ± 16%	Explore
macrophage	44 studies	87% ± 18%	Explore
natural killer cell	44 studies	90% ± 14%	Explore
endothelial cell	43 studies	82% ± 23%	Explore
T cell	39 studies	89% ± 15%	Explore
fibroblast	39 studies	86% ± 24%	Explore
CD8-positive, alpha-beta T cell	36 studies	89% ± 12%	Explore
pericyte	35 studies	85% ± 24%	Explore
CD4-positive, alpha-beta T cell	34 studies	87% ± 16%	Explore
smooth muscle cell	31 studies	85% ± 22%	Explore
conventional dendritic cell	30 studies	96% ± 5%	Explore
dendritic cell	29 studies	84% ± 21%	Explore
mast cell	28 studies	83% ± 25%	Explore
plasmacytoid dendritic cell	27 studies	91% ± 8%	Explore
classical monocyte	26 studies	90% ± 18%	Explore
monocyte	25 studies	90% ± 14%	Explore
plasma cell	25 studies	86% ± 18%	Explore
endothelial cell of lymphatic vessel	25 studies	89% ± 15%	Explore
regulatory T cell	25 studies	89% ± 11%	Explore
non-classical monocyte	23 studies	93% ± 12%	Explore
epithelial cell	23 studies	87% ± 19%	Explore
mature NK T cell	22 studies	89% ± 11%	Explore
gamma-delta T cell	21 studies	92% ± 9%	Explore
basal cell	21 studies	87% ± 18%	Explore
memory B cell	20 studies	95% ± 6%	Explore
connective tissue cell	18 studies	87% ± 19%	Explore
ciliated cell	17 studies	90% ± 11%	Explore
mucosal invariant T cell	17 studies	89% ± 10%	Explore
naive B cell	17 studies	93% ± 7%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	16 studies	88% ± 11%	Explore
capillary endothelial cell	16 studies	84% ± 15%	Explore
endothelial cell of artery	15 studies	88% ± 8%	Explore
microglial cell	15 studies	64% ± 28%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	14 studies	94% ± 6%	Explore
erythrocyte	14 studies	67% ± 20%	Explore
astrocyte	14 studies	64% ± 28%	Explore
CD16-negative, CD56-bright natural killer cell, human	13 studies	88% ± 11%	Explore
innate lymphoid cell	13 studies	91% ± 10%	Explore
CD16-positive, CD56-dim natural killer cell, human	13 studies	86% ± 9%	Explore
CD8-positive, alpha-beta memory T cell	13 studies	91% ± 11%	Explore
neutrophil	13 studies	76% ± 18%	Explore
vein endothelial cell	13 studies	85% ± 12%	Explore
endothelial cell of vascular tree	13 studies	86% ± 25%	Explore
myeloid cell	13 studies	79% ± 27%	Explore
effector memory CD8-positive, alpha-beta T cell	12 studies	86% ± 14%	Explore
CD4-positive, alpha-beta memory T cell	12 studies	89% ± 9%	Explore
myofibroblast cell	12 studies	94% ± 10%	Explore
plasmablast	11 studies	95% ± 4%	Explore
secretory cell	11 studies	94% ± 7%	Explore
oligodendrocyte	11 studies	56% ± 23%	Explore
goblet cell	11 studies	93% ± 20%	Explore
mesothelial cell	11 studies	86% ± 17%	Explore
type I pneumocyte	10 studies	75% ± 25%	Explore
oligodendrocyte precursor cell	10 studies	52% ± 26%	Explore
leukocyte	10 studies	88% ± 21%	Explore
IgG plasma cell	10 studies	84% ± 15%	Explore
type II pneumocyte	9 studies	79% ± 23%	Explore
platelet	9 studies	75% ± 16%	Explore
club cell	9 studies	74% ± 24%	Explore
respiratory goblet cell	9 studies	82% ± 21%	Explore
glutamatergic neuron	9 studies	74% ± 17%	Explore
IgA plasma cell	9 studies	80% ± 21%	Explore
hematopoietic stem cell	9 studies	93% ± 10%	Explore
progenitor cell	8 studies	96% ± 3%	Explore
T follicular helper cell	8 studies	94% ± 6%	Explore
alveolar macrophage	7 studies	93% ± 7%	Explore
mononuclear phagocyte	7 studies	92% ± 7%	Explore
GABAergic neuron	7 studies	64% ± 27%	Explore
enterocyte	7 studies	98% ± 2%	Explore
enteroendocrine cell	7 studies	96% ± 3%	Explore
brush cell	7 studies	82% ± 26%	Explore
glial cell	7 studies	83% ± 19%	Explore
neuron	7 studies	88% ± 8%	Explore
CD4-positive helper T cell	6 studies	89% ± 11%	Explore
hematopoietic precursor cell	6 studies	86% ± 25%	Explore
ionocyte	6 studies	96% ± 4%	Explore
hepatocyte	6 studies	71% ± 28%	Explore
interneuron	6 studies	65% ± 35%	Explore
epithelial cell of proximal tubule	6 studies	85% ± 18%	Explore
renal alpha-intercalated cell	6 studies	97% ± 4%	Explore
abnormal cell	6 studies	90% ± 7%	Explore
lymphocyte	6 studies	70% ± 36%	Explore
adipocyte	6 studies	47% ± 21%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	92% ± 10%	Explore
effector CD8-positive, alpha-beta T cell	6 studies	94% ± 3%	Explore
central memory CD8-positive, alpha-beta T cell	5 studies	89% ± 10%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	5 studies	83% ± 9%	Explore
kidney loop of Henle epithelial cell	5 studies	74% ± 32%	Explore
kidney distal convoluted tubule epithelial cell	5 studies	98% ± 2%	Explore
megakaryocyte	5 studies	91% ± 7%	Explore
erythroblast	5 studies	79% ± 22%	Explore
intestinal crypt stem cell	5 studies	82% ± 32%	Explore
transit amplifying cell	5 studies	93% ± 7%	Explore
retinal cone cell	5 studies	74% ± 30%	Explore
retinal rod cell	5 studies	70% ± 29%	Explore
inflammatory macrophage	5 studies	91% ± 7%	Explore
effector CD4-positive, alpha-beta T cell	5 studies	91% ± 9%	Explore
melanocyte	5 studies	96% ± 4%	Explore
immature B cell	5 studies	95% ± 5%	Explore
CD4-positive, alpha-beta cytotoxic T cell	4 studies	77% ± 17%	Explore
deuterosomal cell	4 studies	92% ± 4%	Explore
duct epithelial cell	4 studies	92% ± 5%	Explore
exhausted T cell	4 studies	87% ± 12%	Explore
cholangiocyte	4 studies	73% ± 27%	Explore
kidney connecting tubule epithelial cell	4 studies	91% ± 15%	Explore
podocyte	4 studies	93% ± 10%	Explore
paneth cell	4 studies	97% ± 3%	Explore
OFF-bipolar cell	4 studies	88% ± 19%	Explore
ON-bipolar cell	4 studies	93% ± 10%	Explore
retinal ganglion cell	4 studies	87% ± 21%	Explore
precursor B cell	4 studies	93% ± 6%	Explore
adventitial cell	4 studies	90% ± 14%	Explore
mucus secreting cell	4 studies	47% ± 20%	Explore
Mueller cell	4 studies	71% ± 29%	Explore
amacrine cell	4 studies	84% ± 22%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	97% ± 4%	Explore
granulocyte	4 studies	82% ± 11%	Explore
IgM plasma cell	4 studies	86% ± 9%	Explore
intermediate monocyte	4 studies	93% ± 9%	Explore
keratinocyte	4 studies	94% ± 5%	Explore
T-helper 17 cell	4 studies	99% ± 1%	Explore
T-helper 1 cell	4 studies	96% ± 3%	Explore
double negative thymocyte	4 studies	94% ± 7%	Explore
Langerhans cell	3 studies	90% ± 12%	Explore
precursor cell	3 studies	72% ± 21%	Explore
squamous epithelial cell	3 studies	78% ± 24%	Explore
endothelial cell of sinusoid	3 studies	89% ± 8%	Explore
hepatic stellate cell	3 studies	81% ± 4%	Explore
glomerular endothelial cell	3 studies	98% ± 1%	Explore
neural crest cell	3 studies	99% ± 1%	Explore
GABAergic amacrine cell	3 studies	78% ± 22%	Explore
glycinergic amacrine cell	3 studies	83% ± 19%	Explore
renal principal cell	3 studies	99% ± 1%	Explore
thymocyte	3 studies	99% ± 1%	Explore
pro-B cell	3 studies	95% ± 4%	Explore
neuroendocrine cell	3 studies	98% ± 1%	Explore
serous secreting cell	3 studies	57% ± 7%	Explore
follicular B cell	3 studies	98% ± 2%	Explore
intraepithelial lymphocyte	3 studies	98% ± 0%	Explore
myoepithelial cell	3 studies	99% ± 1%	Explore
luminal cell of prostate epithelium	3 studies	100% ± 0%	Explore
retina horizontal cell	3 studies	83% ± 14%	Explore
muscle cell	3 studies	61% ± 23%	Explore
ependymal cell	3 studies	60% ± 21%	Explore
granulocyte monocyte progenitor cell	3 studies	70% ± 39%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	96% ± 6%	Explore
germinal center B cell	3 studies	82% ± 9%	Explore
group 3 innate lymphoid cell	3 studies	97% ± 2%	Explore
Schwann cell	3 studies	71% ± 35%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	88% ± 8%	Explore
double-positive, alpha-beta thymocyte	3 studies	95% ± 4%	Explore
progenitor cell of mammary luminal epithelium	3 studies	95% ± 2%	Explore
mural cell	3 studies	77% ± 10%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	18 studies	83% ± 18%	Explore
peripheral blood	17 studies	90% ± 7%	Explore
brain	14 studies	62% ± 27%	Explore
intestine	12 studies	95% ± 5%	Explore
kidney	7 studies	81% ± 22%	Explore
eye	7 studies	72% ± 30%	Explore
liver	6 studies	86% ± 9%	Explore
bone marrow	5 studies	95% ± 4%	Explore
lymph node	4 studies	95% ± 3%	Explore
heart	4 studies	41% ± 19%	Explore
breast	4 studies	96% ± 2%	Explore
uterus	3 studies	99% ± 1%	Explore
prostate	3 studies	100% ± 0%	Explore
esophagus	3 studies	90% ± 4%	Explore
skin	3 studies	95% ± 2%	Explore
adipose	3 studies	88% ± 6%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
adrenal gland	100%	2317143.73	258 / 258	100%	36595.80	230 / 230
brain	100%	2538740.95	2635 / 2642	99%	28907.88	697 / 705
liver	100%	2889937.04	225 / 226	99%	24162.85	402 / 406
esophagus	98%	1237799.66	1416 / 1445	100%	28239.39	183 / 183
stomach	99%	1701693.45	357 / 359	98%	28429.11	281 / 286
kidney	98%	3244728.85	87 / 89	99%	37818.17	893 / 901
prostate	98%	1402258.62	241 / 245	98%	25778.84	493 / 502
pancreas	97%	705430.01	317 / 328	99%	20853.96	177 / 178
skin	98%	822653.82	1779 / 1809	97%	24258.59	460 / 472
breast	98%	1187077.24	450 / 459	97%	18658.17	1088 / 1118
intestine	98%	1496160.27	942 / 966	98%	24933.42	514 / 527
bladder	95%	1169641.62	20 / 21	97%	23800.83	487 / 504
thymus	90%	936085.43	587 / 653	98%	24525.05	593 / 605
lung	90%	721117.58	520 / 578	95%	18603.07	1101 / 1155
uterus	88%	599201.19	149 / 170	96%	16450.16	440 / 459
ovary	69%	490644.39	124 / 180	100%	24249.06	430 / 430
eye	0%	0	0 / 0	100%	32512.31	80 / 80
heart	100%	3573893.82	861 / 861	0%	0	0 / 0
muscle	100%	1930517.10	803 / 803	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	50937.35	1 / 1
adipose	97%	1226270.79	1173 / 1204	0%	0	0 / 0
tonsil	0%	0	0 / 0	93%	10376.95	42 / 45
spleen	92%	756408.09	222 / 241	0%	0	0 / 0
blood vessel	75%	470799.67	1005 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	66%	8222.42	19 / 29
peripheral blood	29%	174630.82	267 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0021549	Biological process	cerebellum development
GO_0009060	Biological process	aerobic respiration
GO_0015990	Biological process	electron transport coupled proton transport
GO_0001666	Biological process	response to hypoxia
GO_0001701	Biological process	in utero embryonic development
GO_0006120	Biological process	mitochondrial electron transport, NADH to ubiquinone
GO_0045471	Biological process	response to ethanol
GO_0035094	Biological process	response to nicotine
GO_0042776	Biological process	proton motive force-driven mitochondrial ATP synthesis
GO_0032981	Biological process	mitochondrial respiratory chain complex I assembly
GO_0045271	Cellular component	respiratory chain complex I
GO_0005743	Cellular component	mitochondrial inner membrane
GO_0048039	Molecular function	ubiquinone binding
GO_0003954	Molecular function	NADH dehydrogenase activity
GO_0008137	Molecular function	NADH dehydrogenase (ubiquinone) activity

Gene name	MT-ND4
Protein name	NADH-ubiquinone oxidoreductase chain 4 (EC 7.1.1.2) (NADH dehydrogenase subunit 4)
Synonyms	ND4 MTND4 NADH4
Description	FUNCTION: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor . Essential for the catalytic activity and assembly of complex I . .
Accessions	P03905 ENST00000361381.2

MT-ND4 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review