GDI2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_1902018Biological processnegative regulation of cilium assembly
GO_0007165Biological processsignal transduction
GO_0016192Biological processvesicle-mediated transport
GO_0007264Biological processsmall GTPase-mediated signal transduction
GO_1903565Biological processnegative regulation of protein localization to cilium
GO_0015031Biological processprotein transport
GO_0035578Cellular componentazurophil granule lumen
GO_0005576Cellular componentextracellular region
GO_0016020Cellular componentmembrane
GO_0070062Cellular componentextracellular exosome
GO_0005794Cellular componentGolgi apparatus
GO_0034774Cellular componentsecretory granule lumen
GO_0005925Cellular componentfocal adhesion
GO_0005829Cellular componentcytosol
GO_0045202Cellular componentsynapse
GO_0005737Cellular componentcytoplasm
GO_0031982Cellular componentvesicle
GO_0031267Molecular functionsmall GTPase binding
GO_0005096Molecular functionGTPase activator activity
GO_0003723Molecular functionRNA binding
GO_0005515Molecular functionprotein binding
GO_0005093Molecular functionRab GDP-dissociation inhibitor activity

IV. Literature review

[source]
Gene nameGDI2
Protein nameRab GDP dissociation inhibitor beta (Rab GDI beta) (Guanosine diphosphate dissociation inhibitor 2) (GDI-2)
Rab GDP dissociation inhibitor
SynonymsHEL-S-46e
hCG_24071
RABGDIB
DescriptionFUNCTION: GDP-dissociation inhibitor preventing the GDP to GTP exchange of most Rab proteins. By keeping these small GTPases in their inactive GDP-bound form regulates intracellular membrane trafficking . Negatively regulates protein transport to the cilium and ciliogenesis through the inhibition of RAB8A . .

FUNCTION: Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP. .

FUNCTION: Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP. .

FUNCTION: Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP. .

FUNCTION: Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP. .

FUNCTION: Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP. .

FUNCTION: Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP. .

FUNCTION: Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP. .

AccessionsP50395
ENST00000447751.5
Q5SX91
ENST00000608581.5
Q5SX87
Q5SX90
ENST00000380127.5
ENST00000609712.1
Q5SX86
V9GYJ7
ENST00000418688.5
ENST00000456041.5
ENST00000380191.9 [P50395-1]
ENST00000380181.7 [P50395-2]
Q6IAT1
V9GYF8