CSDE1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	44 studies	42% ± 15%	Explore
fibroblast	43 studies	37% ± 15%	Explore
macrophage	41 studies	37% ± 12%	Explore
B cell	39 studies	37% ± 12%	Explore
T cell	36 studies	33% ± 13%	Explore
natural killer cell	36 studies	33% ± 11%	Explore
pericyte	35 studies	42% ± 16%	Explore
CD8-positive, alpha-beta T cell	33 studies	37% ± 13%	Explore
CD4-positive, alpha-beta T cell	32 studies	41% ± 14%	Explore
smooth muscle cell	31 studies	42% ± 16%	Explore
conventional dendritic cell	28 studies	46% ± 16%	Explore
classical monocyte	27 studies	45% ± 16%	Explore
regulatory T cell	26 studies	44% ± 12%	Explore
dendritic cell	23 studies	46% ± 21%	Explore
non-classical monocyte	23 studies	44% ± 14%	Explore
epithelial cell	23 studies	43% ± 20%	Explore
mast cell	22 studies	38% ± 15%	Explore
basal cell	22 studies	43% ± 17%	Explore
endothelial cell of lymphatic vessel	21 studies	42% ± 15%	Explore
plasmacytoid dendritic cell	21 studies	46% ± 14%	Explore
monocyte	20 studies	39% ± 13%	Explore
plasma cell	20 studies	38% ± 13%	Explore
memory B cell	20 studies	43% ± 10%	Explore
naive B cell	19 studies	39% ± 11%	Explore
mature NK T cell	18 studies	35% ± 9%	Explore
ciliated cell	18 studies	41% ± 17%	Explore
gamma-delta T cell	18 studies	42% ± 14%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	17 studies	45% ± 14%	Explore
connective tissue cell	17 studies	41% ± 12%	Explore
CD16-negative, CD56-bright natural killer cell, human	15 studies	35% ± 13%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	15 studies	46% ± 14%	Explore
CD16-positive, CD56-dim natural killer cell, human	15 studies	39% ± 10%	Explore
myofibroblast cell	15 studies	40% ± 13%	Explore
mucosal invariant T cell	14 studies	42% ± 16%	Explore
capillary endothelial cell	14 studies	34% ± 12%	Explore
oligodendrocyte	14 studies	28% ± 10%	Explore
myeloid cell	14 studies	42% ± 18%	Explore
CD4-positive, alpha-beta memory T cell	13 studies	44% ± 12%	Explore
CD8-positive, alpha-beta memory T cell	13 studies	43% ± 12%	Explore
endothelial cell of vascular tree	13 studies	38% ± 10%	Explore
astrocyte	13 studies	29% ± 10%	Explore
glutamatergic neuron	12 studies	38% ± 20%	Explore
endothelial cell of artery	12 studies	42% ± 11%	Explore
vein endothelial cell	12 studies	42% ± 10%	Explore
microglial cell	12 studies	28% ± 10%	Explore
type I pneumocyte	11 studies	32% ± 18%	Explore
club cell	11 studies	36% ± 17%	Explore
secretory cell	11 studies	41% ± 8%	Explore
effector memory CD8-positive, alpha-beta T cell	11 studies	42% ± 15%	Explore
abnormal cell	11 studies	41% ± 14%	Explore
oligodendrocyte precursor cell	11 studies	31% ± 13%	Explore
type II pneumocyte	10 studies	38% ± 15%	Explore
plasmablast	10 studies	46% ± 22%	Explore
platelet	10 studies	26% ± 5%	Explore
leukocyte	10 studies	33% ± 8%	Explore
neuron	10 studies	49% ± 21%	Explore
goblet cell	10 studies	37% ± 18%	Explore
mesothelial cell	10 studies	40% ± 19%	Explore
progenitor cell	9 studies	40% ± 15%	Explore
hematopoietic stem cell	9 studies	53% ± 21%	Explore
effector CD8-positive, alpha-beta T cell	8 studies	38% ± 12%	Explore
T follicular helper cell	8 studies	44% ± 8%	Explore
GABAergic neuron	8 studies	40% ± 17%	Explore
alveolar macrophage	7 studies	44% ± 13%	Explore
respiratory goblet cell	7 studies	39% ± 12%	Explore
epithelial cell of proximal tubule	7 studies	29% ± 7%	Explore
IgA plasma cell	7 studies	29% ± 10%	Explore
interneuron	7 studies	40% ± 20%	Explore
precursor B cell	7 studies	46% ± 14%	Explore
innate lymphoid cell	7 studies	36% ± 8%	Explore
erythrocyte	7 studies	38% ± 20%	Explore
ionocyte	6 studies	39% ± 13%	Explore
effector CD4-positive, alpha-beta T cell	6 studies	45% ± 12%	Explore
mononuclear phagocyte	6 studies	44% ± 14%	Explore
kidney loop of Henle epithelial cell	6 studies	30% ± 6%	Explore
renal alpha-intercalated cell	6 studies	38% ± 7%	Explore
enterocyte	6 studies	27% ± 7%	Explore
IgG plasma cell	6 studies	25% ± 5%	Explore
retinal rod cell	6 studies	29% ± 14%	Explore
lymphocyte	6 studies	38% ± 15%	Explore
immature B cell	6 studies	41% ± 11%	Explore
adipocyte	6 studies	22% ± 4%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	48% ± 14%	Explore
hepatocyte	6 studies	37% ± 26%	Explore
CD4-positive helper T cell	5 studies	32% ± 13%	Explore
central memory CD8-positive, alpha-beta T cell	5 studies	40% ± 15%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	5 studies	35% ± 13%	Explore
hematopoietic precursor cell	5 studies	64% ± 17%	Explore
exhausted T cell	5 studies	45% ± 10%	Explore
enteroendocrine cell	5 studies	46% ± 14%	Explore
transit amplifying cell	5 studies	31% ± 15%	Explore
glial cell	5 studies	33% ± 22%	Explore
erythroblast	5 studies	50% ± 30%	Explore
pro-B cell	5 studies	45% ± 17%	Explore
brush cell	5 studies	39% ± 23%	Explore
retinal cone cell	5 studies	43% ± 23%	Explore
adventitial cell	5 studies	26% ± 6%	Explore
cardiac muscle cell	5 studies	23% ± 2%	Explore
granulocyte	5 studies	44% ± 9%	Explore
deuterosomal cell	4 studies	33% ± 8%	Explore
duct epithelial cell	4 studies	40% ± 8%	Explore
squamous epithelial cell	4 studies	45% ± 22%	Explore
pancreatic A cell	4 studies	68% ± 16%	Explore
type B pancreatic cell	4 studies	65% ± 20%	Explore
intestinal crypt stem cell	4 studies	36% ± 2%	Explore
granule cell	4 studies	24% ± 6%	Explore
OFF-bipolar cell	4 studies	40% ± 26%	Explore
retinal ganglion cell	4 studies	81% ± 21%	Explore
amacrine cell	4 studies	42% ± 14%	Explore
retina horizontal cell	4 studies	40% ± 14%	Explore
retinal pigment epithelial cell	4 studies	49% ± 21%	Explore
Mueller cell	4 studies	29% ± 7%	Explore
acinar cell	4 studies	49% ± 28%	Explore
intermediate monocyte	4 studies	54% ± 23%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	51% ± 2%	Explore
luminal cell of prostate epithelium	4 studies	33% ± 8%	Explore
muscle cell	4 studies	42% ± 20%	Explore
neutrophil	4 studies	24% ± 5%	Explore
keratinocyte	4 studies	35% ± 12%	Explore
T-helper 17 cell	4 studies	42% ± 10%	Explore
double negative thymocyte	4 studies	55% ± 11%	Explore
CD4-positive, alpha-beta cytotoxic T cell	3 studies	32% ± 11%	Explore
hillock cell	3 studies	33% ± 9%	Explore
precursor cell	3 studies	54% ± 14%	Explore
pancreatic D cell	3 studies	66% ± 22%	Explore
monocyte-derived dendritic cell	3 studies	42% ± 20%	Explore
glomerular endothelial cell	3 studies	29% ± 9%	Explore
podocyte	3 studies	53% ± 6%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	50% ± 3%	Explore
neural crest cell	3 studies	46% ± 10%	Explore
retinal bipolar neuron	3 studies	45% ± 14%	Explore
GABAergic interneuron	3 studies	24% ± 4%	Explore
extravillous trophoblast	3 studies	49% ± 15%	Explore
placental villous trophoblast	3 studies	51% ± 10%	Explore
megakaryocyte	3 studies	43% ± 2%	Explore
mucus secreting cell	3 studies	39% ± 10%	Explore
serous secreting cell	3 studies	49% ± 8%	Explore
tissue-resident macrophage	3 studies	37% ± 11%	Explore
intraepithelial lymphocyte	3 studies	36% ± 18%	Explore
ON-bipolar cell	3 studies	48% ± 29%	Explore
rod bipolar cell	3 studies	38% ± 10%	Explore
germinal center B cell	3 studies	39% ± 4%	Explore
myoepithelial cell	3 studies	41% ± 4%	Explore
inflammatory macrophage	3 studies	30% ± 6%	Explore
pancreatic ductal cell	3 studies	77% ± 15%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	79% ± 12%	Explore
group 3 innate lymphoid cell	3 studies	50% ± 11%	Explore
melanocyte	3 studies	40% ± 14%	Explore
T-helper 1 cell	3 studies	50% ± 7%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	51% ± 9%	Explore
double-positive, alpha-beta thymocyte	3 studies	64% ± 3%	Explore
progenitor cell of mammary luminal epithelium	3 studies	41% ± 6%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	21 studies	31% ± 16%	Explore
lung	19 studies	40% ± 15%	Explore
peripheral blood	19 studies	46% ± 13%	Explore
intestine	12 studies	34% ± 14%	Explore
kidney	9 studies	34% ± 8%	Explore
eye	9 studies	37% ± 14%	Explore
bone marrow	6 studies	36% ± 18%	Explore
uterus	6 studies	42% ± 17%	Explore
liver	6 studies	39% ± 19%	Explore
pancreas	5 studies	55% ± 26%	Explore
heart	5 studies	20% ± 4%	Explore
adipose	5 studies	25% ± 8%	Explore
lymph node	5 studies	43% ± 6%	Explore
placenta	4 studies	39% ± 10%	Explore
breast	4 studies	42% ± 5%	Explore
prostate	4 studies	30% ± 8%	Explore
ovary	3 studies	34% ± 10%	Explore
adrenal gland	3 studies	34% ± 12%	Explore
esophagus	3 studies	42% ± 28%	Explore
skin	3 studies	32% ± 12%	Explore
thymus	3 studies	45% ± 19%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
breast	100%	33727.26	459 / 459	100%	424.04	1118 / 1118
esophagus	100%	40561.10	1445 / 1445	100%	270.60	183 / 183
ovary	100%	30086.03	180 / 180	100%	240.22	430 / 430
uterus	100%	32104.59	170 / 170	100%	310.40	458 / 459
thymus	100%	27112.74	652 / 653	100%	375.67	604 / 605
lung	100%	29132.96	576 / 578	100%	292.49	1155 / 1155
stomach	100%	26276.26	359 / 359	100%	241.52	285 / 286
intestine	100%	43604.52	966 / 966	100%	250.59	525 / 527
bladder	100%	41124.86	21 / 21	100%	289.38	502 / 504
prostate	100%	29767.50	244 / 245	100%	394.76	502 / 502
skin	100%	32302.52	1808 / 1809	99%	335.08	468 / 472
brain	99%	19140.55	2617 / 2642	100%	247.28	705 / 705
kidney	100%	20199.39	89 / 89	99%	263.82	888 / 901
pancreas	98%	16751.01	321 / 328	100%	277.79	178 / 178
adrenal gland	100%	23107.29	257 / 258	90%	146.97	208 / 230
liver	82%	9368.61	186 / 226	98%	175.58	398 / 406
adipose	100%	37368.28	1204 / 1204	0%	0	0 / 0
blood vessel	100%	46935.73	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	233.73	29 / 29
muscle	100%	137170.97	803 / 803	0%	0	0 / 0
spleen	100%	17676.91	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	309.99	45 / 45
ureter	0%	0	0 / 0	100%	122.81	1 / 1
eye	0%	0	0 / 0	99%	216.04	79 / 80
heart	95%	32077.70	814 / 861	0%	0	0 / 0
peripheral blood	90%	19227.96	838 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_2000767	Biological process	positive regulation of cytoplasmic translation
GO_0034063	Biological process	stress granule assembly
GO_0006446	Biological process	regulation of translational initiation
GO_0070934	Biological process	CRD-mediated mRNA stabilization
GO_0008584	Biological process	male gonad development
GO_1900152	Biological process	negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO_0070966	Biological process	nuclear-transcribed mRNA catabolic process, no-go decay
GO_0075522	Biological process	IRES-dependent viral translational initiation
GO_0005886	Cellular component	plasma membrane
GO_0106002	Cellular component	mCRD-mediated mRNA stability complex
GO_0005794	Cellular component	Golgi apparatus
GO_0000932	Cellular component	P-body
GO_0005829	Cellular component	cytosol
GO_0070937	Cellular component	CRD-mediated mRNA stability complex
GO_0010494	Cellular component	cytoplasmic stress granule
GO_1905172	Molecular function	RISC complex binding
GO_0003723	Molecular function	RNA binding
GO_0035613	Molecular function	RNA stem-loop binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	CSDE1
Protein name	CSDE1 protein Cold shock domain containing E1 Cold shock domain-containing protein E1 (N-ras upstream gene protein) (Protein UNR)
Synonyms	KIAA0885 UNR D1S155E NRU
Description	FUNCTION: RNA-binding protein involved in translationally coupled mRNA turnover . Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain . Required for efficient formation of stress granules . .; FUNCTION: (Microbial infection) Required for internal initiation of translation of human rhinovirus RNA. .
Accessions	ENST00000689217.1 [O75534-1] ENST00000685676.1 ENST00000610726.5 [O75534-4] A0A8I5KV85 ENST00000686781.1 A0A8I5KPJ6 A0A8I5KNL1 ENST00000693311.1 ENST00000686667.1 A0A8I5QJA6 ENST00000529046.6 A0A8I5KXH5 A0A8I5KW72 ENST00000690013.1 ENST00000689510.1 ENST00000690420.1 E9PLD4 ENST00000692629.1 ENST00000689885.1 ENST00000687759.1 ENST00000534389.2 ENST00000684913.1 [O75534-2] ENST00000692044.1 ENST00000530886.5 ENST00000438362.7 [O75534-1] ENST00000534699.5 [O75534-1] A0A8I5KPC0 A0A8I5KW29 ENST00000689989.1 [O75534-1] A0A8I5KYL4 A0A8I5KYL8 ENST00000691403.1 A0A8I5KWW0 ENST00000692719.1 [O75534-1] O75534 E9PKN4 ENST00000686235.1 [O75534-2] ENST00000686025.1 [O75534-2] E9PLT0 A0A8I5KXL1 ENST00000688611.1 A0A1Y8EMC9 ENST00000525878.5 A0A8I5KS07 A0A8I5KYY8 A0A8I5QKX0 E9PNG3 ENST00000690207.1 ENST00000691032.1 E9PJK7 ENST00000525970.5 ENST00000369530.5 [O75534-3] ENST00000339438.10 [O75534-2] A0A8I5KPQ8 ENST00000688211.1 [O75534-4] ENST00000691377.1 ENST00000693467.1 [O75534-2] ENST00000358528.9 [O75534-1] ENST00000525132.1 ENST00000689727.1 ENST00000689732.1 [O75534-2] Q8WU01 ENST00000261443.9 [O75534-2] ENST00000692672.1 A0A8I5KTQ3

CSDE1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review