BTF3 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
B cell	48 studies	77% ± 21%	Explore
macrophage	41 studies	67% ± 23%	Explore
natural killer cell	41 studies	75% ± 17%	Explore
endothelial cell	41 studies	67% ± 26%	Explore
fibroblast	39 studies	75% ± 23%	Explore
CD8-positive, alpha-beta T cell	37 studies	76% ± 21%	Explore
T cell	36 studies	74% ± 21%	Explore
CD4-positive, alpha-beta T cell	34 studies	82% ± 19%	Explore
pericyte	31 studies	80% ± 21%	Explore
conventional dendritic cell	31 studies	87% ± 14%	Explore
dendritic cell	27 studies	78% ± 22%	Explore
smooth muscle cell	27 studies	79% ± 24%	Explore
classical monocyte	27 studies	79% ± 15%	Explore
regulatory T cell	27 studies	86% ± 14%	Explore
plasmacytoid dendritic cell	26 studies	86% ± 9%	Explore
monocyte	24 studies	68% ± 23%	Explore
non-classical monocyte	24 studies	83% ± 12%	Explore
epithelial cell	24 studies	79% ± 21%	Explore
plasma cell	23 studies	66% ± 20%	Explore
mature NK T cell	22 studies	69% ± 23%	Explore
basal cell	22 studies	82% ± 23%	Explore
mast cell	21 studies	67% ± 22%	Explore
endothelial cell of lymphatic vessel	21 studies	81% ± 16%	Explore
memory B cell	20 studies	90% ± 7%	Explore
gamma-delta T cell	19 studies	81% ± 14%	Explore
naive B cell	19 studies	84% ± 9%	Explore
connective tissue cell	19 studies	81% ± 18%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	18 studies	85% ± 16%	Explore
ciliated cell	17 studies	72% ± 17%	Explore
mucosal invariant T cell	16 studies	81% ± 17%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	15 studies	88% ± 19%	Explore
CD16-positive, CD56-dim natural killer cell, human	15 studies	75% ± 16%	Explore
endothelial cell of artery	15 studies	62% ± 26%	Explore
CD16-negative, CD56-bright natural killer cell, human	14 studies	76% ± 21%	Explore
capillary endothelial cell	14 studies	63% ± 22%	Explore
myofibroblast cell	14 studies	86% ± 13%	Explore
vein endothelial cell	14 studies	67% ± 26%	Explore
CD4-positive, alpha-beta memory T cell	13 studies	78% ± 23%	Explore
myeloid cell	13 studies	77% ± 18%	Explore
effector memory CD8-positive, alpha-beta T cell	12 studies	73% ± 22%	Explore
innate lymphoid cell	12 studies	80% ± 13%	Explore
plasmablast	12 studies	78% ± 14%	Explore
CD8-positive, alpha-beta memory T cell	12 studies	82% ± 15%	Explore
secretory cell	12 studies	85% ± 17%	Explore
endothelial cell of vascular tree	12 studies	83% ± 23%	Explore
goblet cell	11 studies	63% ± 23%	Explore
erythrocyte	10 studies	74% ± 17%	Explore
T follicular helper cell	10 studies	85% ± 9%	Explore
progenitor cell	10 studies	85% ± 18%	Explore
abnormal cell	10 studies	75% ± 23%	Explore
mesothelial cell	10 studies	84% ± 21%	Explore
type I pneumocyte	9 studies	55% ± 22%	Explore
type II pneumocyte	9 studies	71% ± 27%	Explore
club cell	9 studies	80% ± 20%	Explore
leukocyte	9 studies	78% ± 22%	Explore
neutrophil	9 studies	55% ± 19%	Explore
hematopoietic stem cell	9 studies	89% ± 25%	Explore
platelet	8 studies	45% ± 22%	Explore
effector CD8-positive, alpha-beta T cell	8 studies	79% ± 24%	Explore
neuron	8 studies	59% ± 28%	Explore
IgG plasma cell	8 studies	50% ± 16%	Explore
microglial cell	8 studies	56% ± 29%	Explore
respiratory goblet cell	7 studies	69% ± 21%	Explore
mononuclear phagocyte	7 studies	69% ± 27%	Explore
epithelial cell of proximal tubule	7 studies	67% ± 18%	Explore
enterocyte	7 studies	66% ± 19%	Explore
IgA plasma cell	7 studies	54% ± 21%	Explore
transit amplifying cell	7 studies	60% ± 25%	Explore
astrocyte	7 studies	39% ± 20%	Explore
brush cell	7 studies	59% ± 32%	Explore
alveolar macrophage	6 studies	70% ± 25%	Explore
ionocyte	6 studies	77% ± 7%	Explore
effector CD4-positive, alpha-beta T cell	6 studies	89% ± 10%	Explore
kidney loop of Henle epithelial cell	6 studies	65% ± 9%	Explore
renal alpha-intercalated cell	6 studies	85% ± 7%	Explore
enteroendocrine cell	6 studies	70% ± 27%	Explore
intestinal crypt stem cell	6 studies	73% ± 27%	Explore
precursor B cell	6 studies	91% ± 7%	Explore
immature B cell	6 studies	89% ± 9%	Explore
intermediate monocyte	6 studies	74% ± 30%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	90% ± 8%	Explore
interneuron	6 studies	39% ± 26%	Explore
CD4-positive helper T cell	5 studies	77% ± 14%	Explore
central memory CD8-positive, alpha-beta T cell	5 studies	84% ± 10%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	5 studies	78% ± 10%	Explore
hematopoietic precursor cell	5 studies	86% ± 22%	Explore
exhausted T cell	5 studies	86% ± 7%	Explore
kidney distal convoluted tubule epithelial cell	5 studies	75% ± 18%	Explore
oligodendrocyte	5 studies	31% ± 9%	Explore
erythroblast	5 studies	82% ± 11%	Explore
retinal ganglion cell	5 studies	67% ± 33%	Explore
retinal rod cell	5 studies	45% ± 21%	Explore
pro-B cell	5 studies	79% ± 30%	Explore
neuroendocrine cell	5 studies	80% ± 17%	Explore
glial cell	5 studies	57% ± 24%	Explore
T-helper 17 cell	5 studies	88% ± 11%	Explore
group 3 innate lymphoid cell	5 studies	89% ± 5%	Explore
mucus secreting cell	5 studies	61% ± 26%	Explore
double negative thymocyte	5 studies	92% ± 4%	Explore
granulocyte	5 studies	81% ± 10%	Explore
glutamatergic neuron	5 studies	35% ± 10%	Explore
CD4-positive, alpha-beta cytotoxic T cell	4 studies	70% ± 30%	Explore
deuterosomal cell	4 studies	65% ± 21%	Explore
duct epithelial cell	4 studies	89% ± 1%	Explore
pancreatic A cell	4 studies	82% ± 11%	Explore
type B pancreatic cell	4 studies	81% ± 12%	Explore
glomerular endothelial cell	4 studies	59% ± 16%	Explore
podocyte	4 studies	80% ± 14%	Explore
OFF-bipolar cell	4 studies	47% ± 32%	Explore
ON-bipolar cell	4 studies	47% ± 32%	Explore
retinal cone cell	4 studies	58% ± 26%	Explore
lymphocyte	4 studies	90% ± 3%	Explore
amacrine cell	4 studies	56% ± 21%	Explore
retina horizontal cell	4 studies	46% ± 22%	Explore
retinal pigment epithelial cell	4 studies	45% ± 27%	Explore
adventitial cell	4 studies	77% ± 13%	Explore
acinar cell	4 studies	82% ± 10%	Explore
germinal center B cell	4 studies	89% ± 7%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	94% ± 8%	Explore
GABAergic neuron	4 studies	26% ± 7%	Explore
oligodendrocyte precursor cell	4 studies	60% ± 22%	Explore
megakaryocyte-erythroid progenitor cell	4 studies	78% ± 36%	Explore
hepatocyte	4 studies	53% ± 26%	Explore
melanocyte	4 studies	76% ± 11%	Explore
T-helper 1 cell	4 studies	93% ± 6%	Explore
precursor cell	3 studies	95% ± 2%	Explore
squamous epithelial cell	3 studies	59% ± 21%	Explore
pancreatic D cell	3 studies	81% ± 11%	Explore
monocyte-derived dendritic cell	3 studies	95% ± 6%	Explore
renal beta-intercalated cell	3 studies	93% ± 6%	Explore
neural crest cell	3 studies	96% ± 3%	Explore
paneth cell	3 studies	67% ± 21%	Explore
retinal bipolar neuron	3 studies	60% ± 25%	Explore
GABAergic amacrine cell	3 studies	25% ± 11%	Explore
glycinergic amacrine cell	3 studies	28% ± 11%	Explore
renal principal cell	3 studies	70% ± 10%	Explore
thymocyte	3 studies	88% ± 8%	Explore
extravillous trophoblast	3 studies	97% ± 2%	Explore
placental villous trophoblast	3 studies	98% ± 1%	Explore
megakaryocyte	3 studies	60% ± 15%	Explore
serous secreting cell	3 studies	74% ± 3%	Explore
tissue-resident macrophage	3 studies	55% ± 27%	Explore
follicular B cell	3 studies	78% ± 11%	Explore
intraepithelial lymphocyte	3 studies	79% ± 11%	Explore
Mueller cell	3 studies	56% ± 7%	Explore
rod bipolar cell	3 studies	50% ± 20%	Explore
muscle cell	3 studies	72% ± 9%	Explore
myoepithelial cell	3 studies	95% ± 1%	Explore
inflammatory macrophage	3 studies	62% ± 18%	Explore
luminal cell of prostate epithelium	3 studies	81% ± 8%	Explore
IgM plasma cell	3 studies	67% ± 13%	Explore
pancreatic ductal cell	3 studies	88% ± 2%	Explore
granulocyte monocyte progenitor cell	3 studies	64% ± 35%	Explore
keratinocyte	3 studies	90% ± 8%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	94% ± 1%	Explore
double-positive, alpha-beta thymocyte	3 studies	95% ± 1%	Explore
progenitor cell of mammary luminal epithelium	3 studies	97% ± 4%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	20 studies	84% ± 9%	Explore
lung	18 studies	75% ± 15%	Explore
intestine	13 studies	67% ± 23%	Explore
brain	11 studies	39% ± 18%	Explore
kidney	9 studies	70% ± 20%	Explore
eye	9 studies	50% ± 22%	Explore
bone marrow	6 studies	70% ± 20%	Explore
lymph node	6 studies	88% ± 5%	Explore
liver	6 studies	68% ± 15%	Explore
pancreas	5 studies	79% ± 13%	Explore
uterus	5 studies	84% ± 13%	Explore
placenta	4 studies	82% ± 19%	Explore
prostate	4 studies	81% ± 24%	Explore
breast	4 studies	88% ± 6%	Explore
heart	3 studies	38% ± 16%	Explore
adipose	3 studies	44% ± 28%	Explore
adrenal gland	3 studies	76% ± 12%	Explore
esophagus	3 studies	77% ± 18%	Explore
skin	3 studies	71% ± 23%	Explore
thymus	3 studies	82% ± 22%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	21125.99	1445 / 1445	100%	155.26	183 / 183
ovary	100%	35461.54	180 / 180	100%	230.10	430 / 430
prostate	100%	17192.49	245 / 245	100%	265.40	502 / 502
stomach	100%	15764.28	359 / 359	100%	221.25	286 / 286
thymus	100%	16192.31	653 / 653	100%	268.63	604 / 605
lung	100%	15986.75	577 / 578	100%	207.07	1155 / 1155
intestine	100%	19521.15	966 / 966	100%	268.51	526 / 527
skin	100%	27318.78	1809 / 1809	100%	247.05	471 / 472
uterus	100%	22561.25	170 / 170	100%	268.61	458 / 459
bladder	100%	22758.19	21 / 21	100%	244.16	502 / 504
breast	100%	24596.42	459 / 459	100%	319.31	1113 / 1118
pancreas	99%	12656.64	326 / 328	100%	208.98	178 / 178
kidney	100%	14552.58	89 / 89	99%	189.94	890 / 901
brain	98%	8053.42	2600 / 2642	100%	184.33	705 / 705
adrenal gland	100%	15706.87	258 / 258	98%	173.07	226 / 230
liver	98%	7390.94	221 / 226	100%	145.43	404 / 406
adipose	100%	23095.42	1204 / 1204	0%	0	0 / 0
blood vessel	100%	21627.12	1335 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	100%	380.02	80 / 80
lymph node	0%	0	0 / 0	100%	389.20	29 / 29
muscle	100%	18967.39	803 / 803	0%	0	0 / 0
spleen	100%	14527.99	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	290.74	45 / 45
ureter	0%	0	0 / 0	100%	79.51	1 / 1
peripheral blood	98%	14189.09	915 / 929	0%	0	0 / 0
heart	97%	11456.20	833 / 861	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

IV. Literature review

[source]

Gene name	BTF3
Protein name	Transcription factor BTF3 Transcription factor BTF3 (Nascent polypeptide-associated complex subunit beta) (NAC-beta) (RNA polymerase B transcription factor 3)
Synonyms	hCG_37844 OK/SW-cl.8 NACB
Description	FUNCTION: When associated with NACA, prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. BTF3 is also a general transcription factor that can form a stable complex with RNA polymerase II. Required for the initiation of transcription. .
Accessions	ENST00000678135.1 H0Y9Y1 ENST00000677654.1 ENST00000335895.12 [P20290-2] A0A7I2YQL2 P20290 A0A7I2V5Y3 ENST00000507081.6 ENST00000509708.2 A0A7I2V3T6 ENST00000676862.1 ENST00000380591.8 [P20290-1] D6RDG3

GO_0015031	Biological process	protein transport
GO_0001701	Biological process	in utero embryonic development
GO_1905551	Biological process	negative regulation of protein localization to endoplasmic reticulum
GO_0005854	Cellular component	nascent polypeptide-associated complex
GO_0005829	Cellular component	cytosol
GO_0005737	Cellular component	cytoplasm
GO_0005634	Cellular component	nucleus
GO_0005515	Molecular function	protein binding
GO_0003723	Molecular function	RNA binding

BTF3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review