TRIR | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
B cell	36 studies	54% ± 16%	Explore
natural killer cell	36 studies	55% ± 14%	Explore
endothelial cell	36 studies	49% ± 20%	Explore
fibroblast	33 studies	48% ± 17%	Explore
CD8-positive, alpha-beta T cell	33 studies	54% ± 18%	Explore
pericyte	30 studies	51% ± 18%	Explore
CD4-positive, alpha-beta T cell	30 studies	53% ± 16%	Explore
T cell	29 studies	51% ± 15%	Explore
macrophage	29 studies	44% ± 15%	Explore
conventional dendritic cell	24 studies	58% ± 14%	Explore
smooth muscle cell	23 studies	52% ± 16%	Explore
classical monocyte	23 studies	52% ± 18%	Explore
regulatory T cell	23 studies	56% ± 16%	Explore
plasmacytoid dendritic cell	22 studies	57% ± 14%	Explore
non-classical monocyte	20 studies	59% ± 18%	Explore
dendritic cell	19 studies	58% ± 21%	Explore
epithelial cell	19 studies	55% ± 20%	Explore
monocyte	18 studies	51% ± 11%	Explore
mature NK T cell	18 studies	51% ± 17%	Explore
naive B cell	18 studies	48% ± 13%	Explore
basal cell	18 studies	50% ± 20%	Explore
endothelial cell of lymphatic vessel	17 studies	58% ± 17%	Explore
gamma-delta T cell	17 studies	52% ± 19%	Explore
memory B cell	17 studies	55% ± 13%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	16 studies	49% ± 16%	Explore
connective tissue cell	16 studies	53% ± 17%	Explore
mast cell	15 studies	51% ± 14%	Explore
mucosal invariant T cell	14 studies	46% ± 17%	Explore
ciliated cell	14 studies	52% ± 21%	Explore
CD16-negative, CD56-bright natural killer cell, human	13 studies	47% ± 19%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	13 studies	54% ± 16%	Explore
plasma cell	13 studies	48% ± 14%	Explore
CD16-positive, CD56-dim natural killer cell, human	13 studies	54% ± 18%	Explore
myofibroblast cell	13 studies	55% ± 18%	Explore
secretory cell	12 studies	45% ± 14%	Explore
capillary endothelial cell	12 studies	44% ± 17%	Explore
myeloid cell	12 studies	50% ± 18%	Explore
endothelial cell of vascular tree	11 studies	55% ± 12%	Explore
plasmablast	10 studies	52% ± 23%	Explore
CD8-positive, alpha-beta memory T cell	10 studies	62% ± 11%	Explore
endothelial cell of artery	10 studies	55% ± 16%	Explore
goblet cell	10 studies	42% ± 17%	Explore
vein endothelial cell	10 studies	55% ± 18%	Explore
effector memory CD8-positive, alpha-beta T cell	9 studies	55% ± 22%	Explore
CD4-positive, alpha-beta memory T cell	9 studies	55% ± 15%	Explore
leukocyte	9 studies	47% ± 16%	Explore
progenitor cell	9 studies	59% ± 16%	Explore
abnormal cell	9 studies	52% ± 18%	Explore
mesothelial cell	9 studies	58% ± 20%	Explore
T follicular helper cell	8 studies	52% ± 15%	Explore
type I pneumocyte	7 studies	43% ± 20%	Explore
type II pneumocyte	7 studies	47% ± 16%	Explore
club cell	7 studies	46% ± 14%	Explore
platelet	7 studies	31% ± 7%	Explore
neuron	7 studies	54% ± 28%	Explore
precursor B cell	7 studies	53% ± 16%	Explore
hematopoietic precursor cell	6 studies	57% ± 27%	Explore
innate lymphoid cell	6 studies	51% ± 13%	Explore
effector CD8-positive, alpha-beta T cell	6 studies	60% ± 13%	Explore
mononuclear phagocyte	6 studies	48% ± 22%	Explore
epithelial cell of proximal tubule	6 studies	45% ± 16%	Explore
renal alpha-intercalated cell	6 studies	51% ± 13%	Explore
enterocyte	6 studies	42% ± 15%	Explore
transit amplifying cell	6 studies	39% ± 21%	Explore
hematopoietic stem cell	6 studies	50% ± 17%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	65% ± 13%	Explore
alveolar macrophage	5 studies	49% ± 14%	Explore
CD4-positive helper T cell	5 studies	44% ± 13%	Explore
exhausted T cell	5 studies	69% ± 9%	Explore
respiratory goblet cell	5 studies	41% ± 24%	Explore
effector CD4-positive, alpha-beta T cell	5 studies	54% ± 12%	Explore
kidney loop of Henle epithelial cell	5 studies	39% ± 3%	Explore
neutrophil	5 studies	29% ± 8%	Explore
enteroendocrine cell	5 studies	58% ± 22%	Explore
IgG plasma cell	5 studies	25% ± 8%	Explore
pro-B cell	5 studies	58% ± 14%	Explore
brush cell	5 studies	46% ± 17%	Explore
immature B cell	5 studies	56% ± 22%	Explore
astrocyte	5 studies	27% ± 14%	Explore
granulocyte	5 studies	51% ± 13%	Explore
interneuron	5 studies	33% ± 21%	Explore
central memory CD8-positive, alpha-beta T cell	4 studies	27% ± 12%	Explore
deuterosomal cell	4 studies	39% ± 12%	Explore
ionocyte	4 studies	43% ± 13%	Explore
squamous epithelial cell	4 studies	40% ± 24%	Explore
glomerular endothelial cell	4 studies	39% ± 10%	Explore
kidney distal convoluted tubule epithelial cell	4 studies	60% ± 20%	Explore
erythroblast	4 studies	52% ± 25%	Explore
intestinal crypt stem cell	4 studies	42% ± 16%	Explore
IgA plasma cell	4 studies	27% ± 9%	Explore
retinal ganglion cell	4 studies	74% ± 25%	Explore
megakaryocyte	4 studies	37% ± 12%	Explore
T-helper 17 cell	4 studies	61% ± 13%	Explore
amacrine cell	4 studies	45% ± 21%	Explore
microglial cell	4 studies	33% ± 12%	Explore
germinal center B cell	4 studies	45% ± 18%	Explore
intermediate monocyte	4 studies	73% ± 15%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	62% ± 4%	Explore
luminal cell of prostate epithelium	4 studies	26% ± 9%	Explore
oligodendrocyte precursor cell	4 studies	40% ± 15%	Explore
erythrocyte	4 studies	58% ± 17%	Explore
group 3 innate lymphoid cell	4 studies	58% ± 12%	Explore
glutamatergic neuron	4 studies	30% ± 10%	Explore
double negative thymocyte	4 studies	54% ± 25%	Explore
CD4-positive, alpha-beta cytotoxic T cell	3 studies	57% ± 19%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	35% ± 18%	Explore
duct epithelial cell	3 studies	41% ± 8%	Explore
pancreatic A cell	3 studies	63% ± 23%	Explore
type B pancreatic cell	3 studies	53% ± 26%	Explore
monocyte-derived dendritic cell	3 studies	56% ± 26%	Explore
podocyte	3 studies	56% ± 15%	Explore
neural crest cell	3 studies	68% ± 10%	Explore
retinal bipolar neuron	3 studies	50% ± 21%	Explore
OFF-bipolar cell	3 studies	49% ± 30%	Explore
ON-bipolar cell	3 studies	48% ± 30%	Explore
renal principal cell	3 studies	41% ± 2%	Explore
thymocyte	3 studies	51% ± 25%	Explore
extravillous trophoblast	3 studies	66% ± 16%	Explore
placental villous trophoblast	3 studies	74% ± 7%	Explore
lymphocyte	3 studies	65% ± 6%	Explore
retina horizontal cell	3 studies	53% ± 16%	Explore
retinal cone cell	3 studies	52% ± 17%	Explore
retinal rod cell	3 studies	34% ± 11%	Explore
adventitial cell	3 studies	32% ± 12%	Explore
mucus secreting cell	3 studies	41% ± 0%	Explore
intraepithelial lymphocyte	3 studies	55% ± 8%	Explore
Mueller cell	3 studies	40% ± 7%	Explore
myoepithelial cell	3 studies	62% ± 4%	Explore
IgM plasma cell	3 studies	34% ± 13%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	67% ± 17%	Explore
glial cell	3 studies	48% ± 25%	Explore
keratinocyte	3 studies	47% ± 11%	Explore
GABAergic neuron	3 studies	24% ± 6%	Explore
oligodendrocyte	3 studies	24% ± 3%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	43% ± 20%	Explore
progenitor cell of mammary luminal epithelium	3 studies	61% ± 3%	Explore
hepatocyte	3 studies	63% ± 18%	Explore
T-helper 1 cell	3 studies	68% ± 7%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	18 studies	52% ± 18%	Explore
lung	15 studies	51% ± 17%	Explore
intestine	11 studies	43% ± 20%	Explore
kidney	8 studies	49% ± 15%	Explore
brain	7 studies	27% ± 8%	Explore
eye	7 studies	38% ± 14%	Explore
bone marrow	5 studies	39% ± 16%	Explore
lymph node	4 studies	50% ± 14%	Explore
uterus	4 studies	59% ± 12%	Explore
breast	4 studies	57% ± 4%	Explore
liver	4 studies	55% ± 21%	Explore
pancreas	3 studies	56% ± 25%	Explore
placenta	3 studies	63% ± 15%	Explore
prostate	3 studies	41% ± 7%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
adrenal gland	100%	5953.16	258 / 258	100%	266.14	230 / 230
esophagus	100%	6842.28	1445 / 1445	100%	228.15	183 / 183
liver	100%	6203.71	226 / 226	100%	236.63	406 / 406
ovary	100%	7235.18	180 / 180	100%	523.11	430 / 430
pancreas	100%	3764.76	328 / 328	100%	253.93	178 / 178
skin	100%	7260.65	1809 / 1809	100%	261.92	472 / 472
thymus	100%	6094.17	653 / 653	100%	306.55	605 / 605
uterus	100%	7209.25	170 / 170	100%	361.39	459 / 459
brain	100%	5514.38	2640 / 2642	100%	278.65	705 / 705
intestine	100%	7518.42	966 / 966	100%	297.68	526 / 527
prostate	100%	6967.86	245 / 245	100%	282.87	501 / 502
kidney	100%	6425.44	89 / 89	100%	202.62	899 / 901
bladder	100%	7259.05	21 / 21	100%	309.98	502 / 504
lung	100%	6409.99	578 / 578	100%	213.87	1150 / 1155
breast	100%	7362.13	459 / 459	99%	245.09	1111 / 1118
stomach	100%	5595.28	359 / 359	99%	274.26	284 / 286
adipose	100%	7287.40	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	353.13	80 / 80
lymph node	0%	0	0 / 0	100%	534.21	29 / 29
spleen	100%	8210.13	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	298.28	45 / 45
ureter	0%	0	0 / 0	100%	512.26	1 / 1
blood vessel	100%	7177.06	1334 / 1335	0%	0	0 / 0
heart	99%	4312.82	856 / 861	0%	0	0 / 0
peripheral blood	99%	6791.58	922 / 929	0%	0	0 / 0
muscle	99%	4078.77	796 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0016075	Biological process	rRNA catabolic process
GO_0008409	Molecular function	5'-3' exonuclease activity
GO_0005515	Molecular function	protein binding
GO_0008408	Molecular function	3'-5' exonuclease activity
GO_0003723	Molecular function	RNA binding

Gene name	TRIR
Protein name	Telomerase RNA component interacting RNase Telomerase RNA component interacting RNase (EC 3.1.13.-) (Exoribonuclease TRIR)
Synonyms	C19orf43
Description	FUNCTION: Exoribonuclease that is part of the telomerase RNA 3' end processing complex and which has the ability to all four unpaired RNA nucleotides from 5' end or 3' end with higher efficiency for purine bases . .
Accessions	ENST00000588213.1 Q9BQ61 K7ELS0 ENST00000242784.5 K7EN60 K7ERU7 ENST00000591254.1 ENST00000592273.5

TRIR report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review