SAT1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
macrophage	54 studies	86% ± 16%	Explore
endothelial cell	48 studies	55% ± 22%	Explore
B cell	47 studies	56% ± 21%	Explore
fibroblast	46 studies	57% ± 24%	Explore
T cell	39 studies	49% ± 19%	Explore
natural killer cell	39 studies	47% ± 16%	Explore
CD8-positive, alpha-beta T cell	36 studies	44% ± 13%	Explore
dendritic cell	34 studies	79% ± 22%	Explore
pericyte	32 studies	46% ± 22%	Explore
smooth muscle cell	31 studies	45% ± 22%	Explore
conventional dendritic cell	31 studies	90% ± 9%	Explore
CD4-positive, alpha-beta T cell	30 studies	47% ± 15%	Explore
mast cell	29 studies	61% ± 21%	Explore
monocyte	29 studies	85% ± 19%	Explore
classical monocyte	29 studies	92% ± 12%	Explore
regulatory T cell	29 studies	62% ± 17%	Explore
non-classical monocyte	28 studies	96% ± 8%	Explore
plasma cell	26 studies	54% ± 18%	Explore
endothelial cell of lymphatic vessel	26 studies	50% ± 20%	Explore
plasmacytoid dendritic cell	24 studies	62% ± 15%	Explore
basal cell	24 studies	77% ± 19%	Explore
epithelial cell	24 studies	78% ± 22%	Explore
mature NK T cell	22 studies	47% ± 15%	Explore
ciliated cell	21 studies	79% ± 20%	Explore
memory B cell	20 studies	60% ± 18%	Explore
microglial cell	20 studies	68% ± 18%	Explore
gamma-delta T cell	20 studies	45% ± 17%	Explore
neutrophil	19 studies	87% ± 18%	Explore
myeloid cell	19 studies	76% ± 24%	Explore
naive B cell	18 studies	54% ± 15%	Explore
astrocyte	18 studies	44% ± 26%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	17 studies	36% ± 14%	Explore
connective tissue cell	16 studies	55% ± 24%	Explore
CD16-positive, CD56-dim natural killer cell, human	15 studies	45% ± 13%	Explore
CD16-negative, CD56-bright natural killer cell, human	15 studies	41% ± 12%	Explore
capillary endothelial cell	15 studies	44% ± 16%	Explore
myofibroblast cell	15 studies	42% ± 16%	Explore
endothelial cell of artery	14 studies	53% ± 19%	Explore
mesothelial cell	14 studies	63% ± 26%	Explore
mucosal invariant T cell	14 studies	39% ± 13%	Explore
endothelial cell of vascular tree	14 studies	70% ± 24%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	13 studies	38% ± 12%	Explore
vein endothelial cell	13 studies	56% ± 18%	Explore
type I pneumocyte	12 studies	68% ± 20%	Explore
type II pneumocyte	12 studies	81% ± 19%	Explore
CD4-positive, alpha-beta memory T cell	12 studies	49% ± 15%	Explore
CD8-positive, alpha-beta memory T cell	12 studies	50% ± 19%	Explore
club cell	12 studies	80% ± 21%	Explore
secretory cell	12 studies	90% ± 14%	Explore
plasmablast	11 studies	57% ± 15%	Explore
platelet	11 studies	65% ± 22%	Explore
leukocyte	11 studies	72% ± 20%	Explore
effector memory CD8-positive, alpha-beta T cell	11 studies	44% ± 16%	Explore
abnormal cell	11 studies	49% ± 21%	Explore
goblet cell	11 studies	58% ± 24%	Explore
progenitor cell	10 studies	64% ± 18%	Explore
adipocyte	10 studies	71% ± 18%	Explore
respiratory goblet cell	9 studies	88% ± 14%	Explore
oligodendrocyte precursor cell	9 studies	35% ± 13%	Explore
epithelial cell of proximal tubule	9 studies	56% ± 20%	Explore
IgG plasma cell	9 studies	46% ± 14%	Explore
T follicular helper cell	9 studies	55% ± 16%	Explore
innate lymphoid cell	9 studies	48% ± 20%	Explore
alveolar macrophage	8 studies	89% ± 8%	Explore
effector CD8-positive, alpha-beta T cell	8 studies	52% ± 19%	Explore
mononuclear phagocyte	8 studies	89% ± 10%	Explore
kidney loop of Henle epithelial cell	8 studies	53% ± 22%	Explore
enterocyte	8 studies	69% ± 27%	Explore
ionocyte	7 studies	85% ± 10%	Explore
renal alpha-intercalated cell	7 studies	70% ± 23%	Explore
kidney distal convoluted tubule epithelial cell	7 studies	70% ± 20%	Explore
IgA plasma cell	7 studies	41% ± 13%	Explore
hematopoietic stem cell	7 studies	48% ± 15%	Explore
brush cell	7 studies	55% ± 22%	Explore
immature B cell	7 studies	47% ± 13%	Explore
mucus secreting cell	7 studies	55% ± 23%	Explore
erythrocyte	7 studies	42% ± 15%	Explore
melanocyte	7 studies	77% ± 22%	Explore
hematopoietic precursor cell	6 studies	53% ± 24%	Explore
effector CD4-positive, alpha-beta T cell	6 studies	68% ± 18%	Explore
GABAergic neuron	6 studies	38% ± 13%	Explore
transit amplifying cell	6 studies	58% ± 27%	Explore
precursor B cell	6 studies	46% ± 7%	Explore
Mueller cell	6 studies	61% ± 21%	Explore
intermediate monocyte	6 studies	95% ± 4%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	43% ± 16%	Explore
hepatocyte	6 studies	65% ± 16%	Explore
duct epithelial cell	5 studies	80% ± 21%	Explore
monocyte-derived dendritic cell	5 studies	95% ± 8%	Explore
endothelial cell of sinusoid	5 studies	35% ± 13%	Explore
kidney connecting tubule epithelial cell	5 studies	78% ± 25%	Explore
neuron	5 studies	33% ± 15%	Explore
intestinal crypt stem cell	5 studies	56% ± 27%	Explore
glutamatergic neuron	5 studies	40% ± 17%	Explore
renal principal cell	5 studies	64% ± 29%	Explore
lymphocyte	5 studies	44% ± 22%	Explore
glial cell	5 studies	55% ± 11%	Explore
retinal pigment epithelial cell	5 studies	50% ± 26%	Explore
adventitial cell	5 studies	60% ± 24%	Explore
cardiac muscle cell	5 studies	48% ± 8%	Explore
erythroblast	5 studies	38% ± 23%	Explore
inflammatory macrophage	5 studies	93% ± 4%	Explore
double negative thymocyte	5 studies	53% ± 12%	Explore
CD4-positive helper T cell	5 studies	52% ± 17%	Explore
granulocyte	5 studies	73% ± 19%	Explore
keratinocyte	5 studies	61% ± 21%	Explore
CD4-positive, alpha-beta cytotoxic T cell	5 studies	39% ± 15%	Explore
deuterosomal cell	4 studies	78% ± 6%	Explore
squamous epithelial cell	4 studies	80% ± 23%	Explore
pancreatic A cell	4 studies	46% ± 19%	Explore
exhausted T cell	4 studies	59% ± 17%	Explore
glomerular endothelial cell	4 studies	53% ± 22%	Explore
renal beta-intercalated cell	4 studies	62% ± 25%	Explore
enteroendocrine cell	4 studies	45% ± 16%	Explore
retinal ganglion cell	4 studies	43% ± 22%	Explore
pro-B cell	4 studies	35% ± 3%	Explore
retina horizontal cell	4 studies	35% ± 13%	Explore
acinar cell	4 studies	53% ± 28%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	93% ± 5%	Explore
luminal cell of prostate epithelium	4 studies	86% ± 22%	Explore
IgM plasma cell	4 studies	48% ± 23%	Explore
group 3 innate lymphoid cell	4 studies	55% ± 7%	Explore
Schwann cell	4 studies	53% ± 30%	Explore
T-helper 17 cell	4 studies	49% ± 20%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	40% ± 7%	Explore
central memory CD8-positive, alpha-beta T cell	4 studies	31% ± 6%	Explore
Langerhans cell	3 studies	86% ± 5%	Explore
type B pancreatic cell	3 studies	35% ± 7%	Explore
extravillous trophoblast	3 studies	95% ± 3%	Explore
placental villous trophoblast	3 studies	93% ± 7%	Explore
megakaryocyte	3 studies	79% ± 8%	Explore
amacrine cell	3 studies	33% ± 11%	Explore
retinal cone cell	3 studies	51% ± 12%	Explore
retinal rod cell	3 studies	27% ± 5%	Explore
serous secreting cell	3 studies	67% ± 14%	Explore
tissue-resident macrophage	3 studies	92% ± 10%	Explore
intraepithelial lymphocyte	3 studies	40% ± 14%	Explore
chondrocyte	3 studies	38% ± 3%	Explore
germinal center B cell	3 studies	52% ± 3%	Explore
myoepithelial cell	3 studies	62% ± 5%	Explore
pancreatic ductal cell	3 studies	94% ± 1%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	62% ± 16%	Explore
oligodendrocyte	3 studies	16% ± 1%	Explore
T-helper 1 cell	3 studies	57% ± 17%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	39% ± 6%	Explore
double-positive, alpha-beta thymocyte	3 studies	55% ± 10%	Explore
interneuron	3 studies	33% ± 15%	Explore
progenitor cell of mammary luminal epithelium	3 studies	64% ± 10%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	22 studies	51% ± 16%	Explore
lung	20 studies	66% ± 20%	Explore
intestine	14 studies	48% ± 18%	Explore
brain	14 studies	36% ± 21%	Explore
kidney	11 studies	55% ± 18%	Explore
liver	10 studies	41% ± 19%	Explore
eye	9 studies	39% ± 20%	Explore
heart	7 studies	31% ± 9%	Explore
uterus	6 studies	68% ± 19%	Explore
lymph node	6 studies	60% ± 16%	Explore
pancreas	5 studies	46% ± 11%	Explore
adipose	5 studies	51% ± 21%	Explore
prostate	5 studies	77% ± 25%	Explore
skin	5 studies	50% ± 23%	Explore
breast	5 studies	63% ± 20%	Explore
placenta	4 studies	72% ± 28%	Explore
bone marrow	4 studies	42% ± 15%	Explore
esophagus	4 studies	46% ± 17%	Explore
ovary	3 studies	51% ± 9%	Explore
adrenal gland	3 studies	48% ± 10%	Explore
thymus	3 studies	47% ± 13%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
thymus	100%	37880.83	653 / 653	100%	1114.66	603 / 605
lung	100%	76471.92	578 / 578	99%	673.39	1147 / 1155
prostate	100%	28989.00	244 / 245	100%	797.93	500 / 502
kidney	100%	34803.11	89 / 89	98%	406.53	879 / 901
stomach	99%	26134.84	356 / 359	98%	417.94	281 / 286
intestine	98%	18764.73	947 / 966	99%	455.37	520 / 527
breast	100%	29155.73	459 / 459	97%	343.90	1081 / 1118
liver	100%	24110.48	226 / 226	96%	328.21	391 / 406
esophagus	96%	16300.77	1384 / 1445	98%	444.72	180 / 183
uterus	91%	13444.71	154 / 170	96%	681.95	439 / 459
ovary	91%	13360.50	163 / 180	87%	292.97	375 / 430
skin	82%	9390.39	1489 / 1809	95%	460.74	450 / 472
brain	82%	9424.20	2164 / 2642	94%	312.40	664 / 705
bladder	81%	9752.33	17 / 21	94%	425.62	474 / 504
pancreas	66%	8538.23	215 / 328	97%	566.25	172 / 178
adrenal gland	100%	18788.91	258 / 258	55%	131.20	126 / 230
lymph node	0%	0	0 / 0	100%	636.76	29 / 29
spleen	100%	54227.45	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	719.96	45 / 45
adipose	100%	37348.68	1203 / 1204	0%	0	0 / 0
peripheral blood	97%	57550.70	905 / 929	0%	0	0 / 0
blood vessel	89%	16698.33	1192 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	89%	338.12	71 / 80
heart	87%	18049.18	749 / 861	0%	0	0 / 0
muscle	7%	564.92	56 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

IV. Literature review

[source]

Gene name	SAT1
Protein name	Diamine acetyltransferase 1 (EC 2.3.1.57) (Polyamine N-acetyltransferase 1) (Putrescine acetyltransferase) (Spermidine/spermine N(1)-acetyltransferase 1) (SSAT) (SSAT-1) Spermidine/spermine N1-acetyltransferase 1 (Spermidine/spermine N1-acetyltransferase alpha variant) Diamine acetyltransferase 1 (EC 2.3.1.57) (Polyamine N-acetyltransferase 1) (Putrescine acetyltransferase) (Spermidine/spermine N(1)-acetyltransferase 1)
Synonyms	SAT
Description	FUNCTION: Enzyme which catalyzes the acetylation of polyamines . Substrate specificity: norspermidine = spermidine >> spermine > N(1)-acetylspermine . This highly regulated enzyme allows a fine attenuation of the intracellular concentration of polyamines . Also involved in the regulation of polyamine transport out of cells . Also acts on 1,3-diaminopropane and 1,5-diaminopentane . .
Accessions	E9PD37 P21673 ENST00000489394.5 Q2TM25 ENST00000379254.5 ENST00000379270.5

GO_0032918	Biological process	spermidine acetylation
GO_0001525	Biological process	angiogenesis
GO_0009447	Biological process	putrescine catabolic process
GO_0006596	Biological process	polyamine biosynthetic process
GO_0005829	Cellular component	cytosol
GO_0004145	Molecular function	diamine N-acetyltransferase activity
GO_0008080	Molecular function	N-acetyltransferase activity
GO_0019809	Molecular function	spermidine binding
GO_0042802	Molecular function	identical protein binding
GO_0005515	Molecular function	protein binding

SAT1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review