PCBP1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	39 studies	47% ± 16%	Explore
macrophage	38 studies	54% ± 18%	Explore
endothelial cell	38 studies	40% ± 15%	Explore
B cell	35 studies	42% ± 14%	Explore
fibroblast	35 studies	40% ± 14%	Explore
CD8-positive, alpha-beta T cell	34 studies	41% ± 17%	Explore
T cell	32 studies	45% ± 18%	Explore
pericyte	29 studies	49% ± 14%	Explore
conventional dendritic cell	29 studies	63% ± 16%	Explore
CD4-positive, alpha-beta T cell	29 studies	46% ± 16%	Explore
classical monocyte	28 studies	61% ± 18%	Explore
regulatory T cell	26 studies	45% ± 19%	Explore
smooth muscle cell	25 studies	45% ± 13%	Explore
non-classical monocyte	24 studies	63% ± 16%	Explore
dendritic cell	23 studies	60% ± 21%	Explore
epithelial cell	21 studies	52% ± 21%	Explore
monocyte	20 studies	57% ± 17%	Explore
basal cell	20 studies	45% ± 19%	Explore
mature NK T cell	19 studies	41% ± 16%	Explore
memory B cell	19 studies	51% ± 12%	Explore
plasmacytoid dendritic cell	19 studies	48% ± 16%	Explore
mast cell	18 studies	42% ± 13%	Explore
gamma-delta T cell	18 studies	48% ± 19%	Explore
naive B cell	18 studies	45% ± 15%	Explore
endothelial cell of lymphatic vessel	17 studies	56% ± 11%	Explore
ciliated cell	16 studies	49% ± 18%	Explore
CD16-negative, CD56-bright natural killer cell, human	15 studies	45% ± 19%	Explore
mucosal invariant T cell	15 studies	39% ± 18%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	15 studies	41% ± 17%	Explore
CD16-positive, CD56-dim natural killer cell, human	15 studies	51% ± 16%	Explore
connective tissue cell	15 studies	49% ± 17%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	14 studies	44% ± 17%	Explore
myeloid cell	14 studies	55% ± 23%	Explore
plasma cell	13 studies	45% ± 13%	Explore
neutrophil	13 studies	43% ± 17%	Explore
capillary endothelial cell	13 studies	42% ± 15%	Explore
myofibroblast cell	13 studies	45% ± 13%	Explore
CD8-positive, alpha-beta memory T cell	12 studies	50% ± 17%	Explore
secretory cell	12 studies	45% ± 12%	Explore
endothelial cell of artery	12 studies	46% ± 14%	Explore
CD4-positive, alpha-beta memory T cell	11 studies	44% ± 20%	Explore
vein endothelial cell	11 studies	48% ± 15%	Explore
endothelial cell of vascular tree	11 studies	48% ± 15%	Explore
plasmablast	10 studies	59% ± 21%	Explore
effector memory CD8-positive, alpha-beta T cell	10 studies	42% ± 14%	Explore
mesothelial cell	10 studies	55% ± 21%	Explore
type I pneumocyte	9 studies	45% ± 15%	Explore
T follicular helper cell	9 studies	52% ± 20%	Explore
leukocyte	9 studies	51% ± 16%	Explore
progenitor cell	9 studies	48% ± 21%	Explore
goblet cell	9 studies	40% ± 17%	Explore
erythrocyte	9 studies	50% ± 27%	Explore
type II pneumocyte	8 studies	45% ± 17%	Explore
innate lymphoid cell	8 studies	49% ± 9%	Explore
platelet	8 studies	33% ± 12%	Explore
abnormal cell	8 studies	51% ± 15%	Explore
alveolar macrophage	7 studies	48% ± 22%	Explore
club cell	7 studies	47% ± 16%	Explore
effector CD8-positive, alpha-beta T cell	7 studies	27% ± 8%	Explore
epithelial cell of proximal tubule	7 studies	41% ± 12%	Explore
enterocyte	7 studies	40% ± 16%	Explore
glutamatergic neuron	7 studies	24% ± 11%	Explore
precursor B cell	7 studies	55% ± 21%	Explore
hematopoietic precursor cell	6 studies	58% ± 21%	Explore
ionocyte	6 studies	46% ± 15%	Explore
respiratory goblet cell	6 studies	42% ± 17%	Explore
mononuclear phagocyte	6 studies	58% ± 20%	Explore
kidney loop of Henle epithelial cell	6 studies	35% ± 6%	Explore
neuron	6 studies	56% ± 26%	Explore
oligodendrocyte	6 studies	24% ± 6%	Explore
erythroblast	6 studies	49% ± 31%	Explore
IgG plasma cell	6 studies	23% ± 5%	Explore
hematopoietic stem cell	6 studies	42% ± 21%	Explore
immature B cell	6 studies	53% ± 17%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	48% ± 14%	Explore
CD4-positive helper T cell	5 studies	40% ± 15%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	5 studies	32% ± 12%	Explore
exhausted T cell	5 studies	40% ± 21%	Explore
effector CD4-positive, alpha-beta T cell	5 studies	26% ± 6%	Explore
IgA plasma cell	5 studies	27% ± 5%	Explore
pro-B cell	5 studies	51% ± 24%	Explore
double negative thymocyte	5 studies	58% ± 22%	Explore
intermediate monocyte	5 studies	64% ± 19%	Explore
granulocyte	5 studies	46% ± 11%	Explore
central memory CD8-positive, alpha-beta T cell	4 studies	27% ± 8%	Explore
deuterosomal cell	4 studies	44% ± 12%	Explore
squamous epithelial cell	4 studies	55% ± 27%	Explore
pancreatic A cell	4 studies	69% ± 23%	Explore
type B pancreatic cell	4 studies	64% ± 26%	Explore
kidney distal convoluted tubule epithelial cell	4 studies	40% ± 4%	Explore
enteroendocrine cell	4 studies	58% ± 10%	Explore
transit amplifying cell	4 studies	39% ± 17%	Explore
retinal ganglion cell	4 studies	54% ± 31%	Explore
brush cell	4 studies	42% ± 22%	Explore
T-helper 17 cell	4 studies	56% ± 14%	Explore
microglial cell	4 studies	38% ± 15%	Explore
adventitial cell	4 studies	36% ± 7%	Explore
acinar cell	4 studies	53% ± 29%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	63% ± 8%	Explore
GABAergic neuron	4 studies	24% ± 4%	Explore
oligodendrocyte precursor cell	4 studies	39% ± 18%	Explore
hepatocyte	4 studies	42% ± 27%	Explore
group 3 innate lymphoid cell	4 studies	67% ± 8%	Explore
T-helper 1 cell	4 studies	53% ± 21%	Explore
CD4-positive, alpha-beta cytotoxic T cell	3 studies	25% ± 5%	Explore
duct epithelial cell	3 studies	34% ± 16%	Explore
precursor cell	3 studies	71% ± 23%	Explore
pancreatic D cell	3 studies	65% ± 28%	Explore
monocyte-derived dendritic cell	3 studies	70% ± 19%	Explore
glomerular endothelial cell	3 studies	26% ± 4%	Explore
podocyte	3 studies	51% ± 5%	Explore
renal alpha-intercalated cell	3 studies	37% ± 5%	Explore
intestinal crypt stem cell	3 studies	36% ± 13%	Explore
neural crest cell	3 studies	58% ± 15%	Explore
renal principal cell	3 studies	38% ± 3%	Explore
thymocyte	3 studies	40% ± 21%	Explore
extravillous trophoblast	3 studies	74% ± 11%	Explore
placental villous trophoblast	3 studies	75% ± 5%	Explore
lymphocyte	3 studies	53% ± 13%	Explore
megakaryocyte	3 studies	57% ± 15%	Explore
neuroendocrine cell	3 studies	57% ± 22%	Explore
amacrine cell	3 studies	36% ± 13%	Explore
astrocyte	3 studies	36% ± 14%	Explore
retina horizontal cell	3 studies	31% ± 15%	Explore
retinal cone cell	3 studies	40% ± 17%	Explore
mucus secreting cell	3 studies	30% ± 2%	Explore
serous secreting cell	3 studies	37% ± 9%	Explore
tissue-resident macrophage	3 studies	48% ± 21%	Explore
intraepithelial lymphocyte	3 studies	50% ± 13%	Explore
Mueller cell	3 studies	32% ± 3%	Explore
muscle cell	3 studies	40% ± 21%	Explore
germinal center B cell	3 studies	61% ± 16%	Explore
myoepithelial cell	3 studies	39% ± 6%	Explore
inflammatory macrophage	3 studies	48% ± 10%	Explore
luminal cell of prostate epithelium	3 studies	28% ± 7%	Explore
IgM plasma cell	3 studies	27% ± 10%	Explore
pancreatic ductal cell	3 studies	75% ± 17%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	78% ± 11%	Explore
glial cell	3 studies	51% ± 21%	Explore
keratinocyte	3 studies	50% ± 18%	Explore
double-positive, alpha-beta thymocyte	3 studies	60% ± 29%	Explore
progenitor cell of mammary luminal epithelium	3 studies	41% ± 2%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	20 studies	47% ± 18%	Explore
lung	18 studies	47% ± 14%	Explore
brain	12 studies	26% ± 11%	Explore
intestine	10 studies	41% ± 14%	Explore
kidney	9 studies	36% ± 12%	Explore
bone marrow	7 studies	32% ± 15%	Explore
liver	7 studies	41% ± 22%	Explore
eye	6 studies	32% ± 14%	Explore
lymph node	6 studies	43% ± 21%	Explore
pancreas	5 studies	58% ± 29%	Explore
uterus	5 studies	51% ± 16%	Explore
placenta	4 studies	55% ± 22%	Explore
prostate	4 studies	35% ± 10%	Explore
breast	4 studies	47% ± 5%	Explore
adrenal gland	3 studies	42% ± 16%	Explore
esophagus	3 studies	48% ± 23%	Explore
thymus	3 studies	54% ± 26%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	5482.17	1444 / 1445	100%	21.51	183 / 183
ovary	100%	4376.61	180 / 180	100%	35.82	429 / 430
stomach	100%	4197.98	359 / 359	99%	30.52	283 / 286
intestine	100%	5551.01	966 / 966	95%	32.20	503 / 527
skin	100%	5657.52	1808 / 1809	90%	9.05	427 / 472
lung	100%	5793.30	577 / 578	88%	9.76	1014 / 1155
bladder	100%	5462.24	21 / 21	86%	17.89	434 / 504
breast	100%	6019.98	459 / 459	86%	8.30	958 / 1118
uterus	100%	5713.12	170 / 170	86%	10.14	393 / 459
pancreas	99%	3329.16	325 / 328	85%	8.05	151 / 178
prostate	100%	3263.10	244 / 245	83%	7.12	416 / 502
kidney	100%	4229.54	89 / 89	81%	8.54	727 / 901
thymus	100%	4311.52	652 / 653	76%	7.43	459 / 605
adrenal gland	100%	6406.19	258 / 258	71%	6.35	163 / 230
brain	96%	2610.68	2533 / 2642	71%	6.56	503 / 705
liver	97%	3171.65	219 / 226	70%	6.28	283 / 406
adipose	100%	6875.36	1204 / 1204	0%	0	0 / 0
blood vessel	100%	7038.01	1335 / 1335	0%	0	0 / 0
muscle	100%	11717.75	803 / 803	0%	0	0 / 0
spleen	100%	5247.01	241 / 241	0%	0	0 / 0
peripheral blood	100%	10121.15	928 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	98%	12.04	78 / 80
heart	94%	3458.28	811 / 861	0%	0	0 / 0
tonsil	0%	0	0 / 0	89%	8.68	40 / 45
lymph node	0%	0	0 / 0	66%	11.77	19 / 29
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

III. Associated gene sets

GO_0039694	Biological process	viral RNA genome replication
GO_0045944	Biological process	positive regulation of transcription by RNA polymerase II
GO_0016020	Cellular component	membrane
GO_0036464	Cellular component	cytoplasmic ribonucleoprotein granule
GO_0016607	Cellular component	nuclear speck
GO_0070062	Cellular component	extracellular exosome
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0014069	Cellular component	postsynaptic density
GO_0005737	Cellular component	cytoplasm
GO_1990904	Cellular component	ribonucleoprotein complex
GO_0005634	Cellular component	nucleus
GO_0000981	Molecular function	DNA-binding transcription factor activity, RNA polymerase II-specific
GO_0003697	Molecular function	single-stranded DNA binding
GO_0045296	Molecular function	cadherin binding
GO_0003729	Molecular function	mRNA binding
GO_0003723	Molecular function	RNA binding
GO_0005515	Molecular function	protein binding
GO_0098847	Molecular function	sequence-specific single stranded DNA binding

Gene name	PCBP1
Protein name	Epididymis secretory protein Li 85 (Poly(RC) binding protein 1) Poly(rC)-binding protein 1 (Alpha-CP1) (Heterogeneous nuclear ribonucleoprotein E1) (hnRNP E1) (Nucleic acid-binding protein SUB2.3)
Synonyms	HEL-S-85 hCG_1776997
Description	FUNCTION: Single-stranded nucleic acid binding protein that binds preferentially to oligo dC . Together with PCBP2, required for erythropoiesis, possibly by regulating mRNA splicing (By similarity). .; FUNCTION: (Microbial infection) In case of infection by poliovirus, plays a role in initiation of viral RNA replication in concert with the viral protein 3CD. .
Accessions	Q53SS8 ENST00000303577.7 Q15365

PCBP1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review