Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| peripheral blood | 20 studies | 47% ± 15% | |
| lung | 18 studies | 58% ± 17% | |
| intestine | 12 studies | 50% ± 20% | |
| brain | 11 studies | 33% ± 11% | |
| kidney | 9 studies | 58% ± 14% | |
| eye | 8 studies | 49% ± 17% | |
| liver | 7 studies | 45% ± 21% | |
| bone marrow | 6 studies | 40% ± 15% | |
| lymph node | 6 studies | 51% ± 21% | |
| pancreas | 5 studies | 67% ± 20% | |
| uterus | 5 studies | 63% ± 23% | |
| placenta | 4 studies | 62% ± 22% | |
| prostate | 4 studies | 52% ± 10% | |
| breast | 4 studies | 61% ± 6% | |
| adipose | 3 studies | 25% ± 10% | |
| adrenal gland | 3 studies | 55% ± 8% | |
| esophagus | 3 studies | 61% ± 23% | |
| skin | 3 studies | 47% ± 18% | |
| thymus | 3 studies | 65% ± 20% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| adrenal gland | 100% | 6391.45 | 258 / 258 | 100% | 794.25 | 230 / 230 |
| esophagus | 100% | 6769.21 | 1445 / 1445 | 100% | 548.11 | 183 / 183 |
| ovary | 100% | 5212.31 | 180 / 180 | 100% | 948.03 | 430 / 430 |
| uterus | 100% | 5387.71 | 170 / 170 | 100% | 1125.42 | 459 / 459 |
| skin | 100% | 5364.71 | 1808 / 1809 | 100% | 779.99 | 472 / 472 |
| kidney | 100% | 6266.57 | 89 / 89 | 100% | 708.94 | 900 / 901 |
| brain | 100% | 7854.09 | 2638 / 2642 | 100% | 751.26 | 705 / 705 |
| thymus | 100% | 4816.27 | 651 / 653 | 100% | 991.79 | 605 / 605 |
| intestine | 100% | 6611.67 | 966 / 966 | 100% | 794.77 | 525 / 527 |
| prostate | 100% | 5385.08 | 244 / 245 | 100% | 789.20 | 502 / 502 |
| liver | 100% | 3334.73 | 225 / 226 | 100% | 593.28 | 406 / 406 |
| stomach | 100% | 4851.49 | 359 / 359 | 99% | 676.38 | 284 / 286 |
| breast | 100% | 5332.63 | 459 / 459 | 99% | 778.41 | 1110 / 1118 |
| bladder | 100% | 5958.05 | 21 / 21 | 99% | 981.23 | 499 / 504 |
| lung | 99% | 4324.46 | 575 / 578 | 99% | 673.22 | 1147 / 1155 |
| pancreas | 95% | 2280.80 | 311 / 328 | 99% | 678.08 | 176 / 178 |
| adipose | 100% | 5518.68 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 835.86 | 29 / 29 |
| muscle | 100% | 9760.27 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 3245.22 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 826.96 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 1501.95 | 1 / 1 |
| blood vessel | 100% | 6087.16 | 1333 / 1335 | 0% | 0 | 0 / 0 |
| heart | 99% | 13022.20 | 852 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 99% | 789.49 | 79 / 80 |
| peripheral blood | 45% | 1949.99 | 422 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0009060 | Biological process | aerobic respiration |
| GO_0006120 | Biological process | mitochondrial electron transport, NADH to ubiquinone |
| GO_0042776 | Biological process | proton motive force-driven mitochondrial ATP synthesis |
| GO_0055085 | Biological process | transmembrane transport |
| GO_0032981 | Biological process | mitochondrial respiratory chain complex I assembly |
| GO_0005758 | Cellular component | mitochondrial intermembrane space |
| GO_0045271 | Cellular component | respiratory chain complex I |
| GO_0005743 | Cellular component | mitochondrial inner membrane |
| GO_0005739 | Cellular component | mitochondrion |
| GO_0008137 | Molecular function | NADH dehydrogenase (ubiquinone) activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | NDUFS5 |
| Protein name | NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 (Complex I-15 kDa) (CI-15 kDa) (NADH-ubiquinone oxidoreductase 15 kDa subunit) NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 (Complex I-15 kDa) (NADH-ubiquinone oxidoreductase 15 kDa subunit) |
| Synonyms | hCG_1782706 |
| Description | FUNCTION: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. . FUNCTION: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. . |
| Accessions | Q6IBA0 O43920 ENST00000372969.8 ENST00000372967.3 |