MT-ND4L | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
B cell	42 studies	67% ± 27%	Explore
macrophage	39 studies	63% ± 23%	Explore
endothelial cell	37 studies	55% ± 23%	Explore
natural killer cell	36 studies	69% ± 24%	Explore
T cell	34 studies	59% ± 29%	Explore
fibroblast	34 studies	52% ± 23%	Explore
CD8-positive, alpha-beta T cell	32 studies	68% ± 26%	Explore
pericyte	29 studies	55% ± 23%	Explore
conventional dendritic cell	29 studies	73% ± 21%	Explore
CD4-positive, alpha-beta T cell	29 studies	68% ± 24%	Explore
smooth muscle cell	26 studies	51% ± 26%	Explore
regulatory T cell	24 studies	75% ± 26%	Explore
plasmacytoid dendritic cell	23 studies	72% ± 26%	Explore
dendritic cell	22 studies	60% ± 28%	Explore
mast cell	22 studies	62% ± 22%	Explore
classical monocyte	22 studies	70% ± 22%	Explore
monocyte	21 studies	60% ± 22%	Explore
epithelial cell	21 studies	54% ± 27%	Explore
plasma cell	20 studies	69% ± 26%	Explore
endothelial cell of lymphatic vessel	20 studies	57% ± 19%	Explore
mature NK T cell	20 studies	66% ± 27%	Explore
non-classical monocyte	20 studies	81% ± 16%	Explore
memory B cell	19 studies	86% ± 15%	Explore
gamma-delta T cell	18 studies	78% ± 19%	Explore
naive B cell	18 studies	80% ± 22%	Explore
basal cell	18 studies	54% ± 26%	Explore
ciliated cell	17 studies	69% ± 19%	Explore
mucosal invariant T cell	15 studies	83% ± 23%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	15 studies	78% ± 26%	Explore
connective tissue cell	15 studies	52% ± 21%	Explore
CD16-negative, CD56-bright natural killer cell, human	14 studies	79% ± 24%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	13 studies	92% ± 14%	Explore
CD16-positive, CD56-dim natural killer cell, human	13 studies	84% ± 21%	Explore
capillary endothelial cell	13 studies	48% ± 19%	Explore
effector memory CD8-positive, alpha-beta T cell	12 studies	75% ± 22%	Explore
CD8-positive, alpha-beta memory T cell	12 studies	83% ± 19%	Explore
endothelial cell of vascular tree	12 studies	43% ± 23%	Explore
myeloid cell	12 studies	58% ± 30%	Explore
innate lymphoid cell	11 studies	62% ± 21%	Explore
CD4-positive, alpha-beta memory T cell	11 studies	87% ± 20%	Explore
secretory cell	11 studies	55% ± 27%	Explore
endothelial cell of artery	11 studies	52% ± 21%	Explore
erythrocyte	11 studies	64% ± 26%	Explore
myofibroblast cell	11 studies	52% ± 18%	Explore
plasmablast	10 studies	84% ± 21%	Explore
neutrophil	10 studies	39% ± 21%	Explore
astrocyte	10 studies	37% ± 22%	Explore
goblet cell	10 studies	52% ± 22%	Explore
vein endothelial cell	10 studies	47% ± 18%	Explore
type I pneumocyte	8 studies	63% ± 25%	Explore
type II pneumocyte	8 studies	60% ± 25%	Explore
platelet	8 studies	53% ± 20%	Explore
glutamatergic neuron	8 studies	40% ± 27%	Explore
progenitor cell	8 studies	50% ± 20%	Explore
mesothelial cell	8 studies	60% ± 21%	Explore
hematopoietic stem cell	8 studies	82% ± 27%	Explore
alveolar macrophage	7 studies	66% ± 17%	Explore
T follicular helper cell	7 studies	72% ± 26%	Explore
club cell	7 studies	62% ± 27%	Explore
respiratory goblet cell	7 studies	69% ± 23%	Explore
oligodendrocyte	7 studies	35% ± 16%	Explore
abnormal cell	7 studies	63% ± 29%	Explore
enterocyte	7 studies	52% ± 26%	Explore
leukocyte	7 studies	39% ± 15%	Explore
IgA plasma cell	7 studies	57% ± 28%	Explore
IgG plasma cell	7 studies	54% ± 24%	Explore
microglial cell	7 studies	46% ± 24%	Explore
CD4-positive helper T cell	6 studies	52% ± 21%	Explore
hematopoietic precursor cell	6 studies	65% ± 33%	Explore
mononuclear phagocyte	6 studies	44% ± 10%	Explore
epithelial cell of proximal tubule	6 studies	63% ± 24%	Explore
renal alpha-intercalated cell	6 studies	79% ± 19%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	77% ± 21%	Explore
neuron	6 studies	45% ± 13%	Explore
central memory CD8-positive, alpha-beta T cell	5 studies	84% ± 19%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	5 studies	84% ± 14%	Explore
ionocyte	5 studies	79% ± 9%	Explore
hepatocyte	5 studies	59% ± 29%	Explore
GABAergic neuron	5 studies	51% ± 28%	Explore
oligodendrocyte precursor cell	5 studies	30% ± 10%	Explore
kidney distal convoluted tubule epithelial cell	5 studies	76% ± 27%	Explore
intestinal crypt stem cell	5 studies	45% ± 28%	Explore
erythroblast	5 studies	65% ± 26%	Explore
inflammatory macrophage	5 studies	65% ± 17%	Explore
effector CD8-positive, alpha-beta T cell	5 studies	83% ± 28%	Explore
CD4-positive, alpha-beta cytotoxic T cell	4 studies	69% ± 33%	Explore
deuterosomal cell	4 studies	69% ± 7%	Explore
exhausted T cell	4 studies	86% ± 17%	Explore
cholangiocyte	4 studies	52% ± 26%	Explore
endothelial cell of sinusoid	4 studies	60% ± 21%	Explore
enteroendocrine cell	4 studies	54% ± 15%	Explore
transit amplifying cell	4 studies	57% ± 22%	Explore
retinal cone cell	4 studies	54% ± 34%	Explore
retinal rod cell	4 studies	43% ± 21%	Explore
lymphocyte	4 studies	80% ± 14%	Explore
megakaryocyte	4 studies	49% ± 25%	Explore
precursor B cell	4 studies	87% ± 11%	Explore
brush cell	4 studies	60% ± 30%	Explore
adventitial cell	4 studies	59% ± 23%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	62% ± 23%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	78% ± 34%	Explore
megakaryocyte-erythroid progenitor cell	4 studies	60% ± 40%	Explore
glial cell	4 studies	49% ± 23%	Explore
keratinocyte	4 studies	45% ± 7%	Explore
T-helper 17 cell	4 studies	54% ± 27%	Explore
double negative thymocyte	4 studies	74% ± 26%	Explore
immature B cell	4 studies	97% ± 3%	Explore
duct epithelial cell	3 studies	70% ± 13%	Explore
squamous epithelial cell	3 studies	56% ± 25%	Explore
hepatic stellate cell	3 studies	38% ± 4%	Explore
podocyte	3 studies	59% ± 27%	Explore
glomerular endothelial cell	3 studies	74% ± 17%	Explore
kidney connecting tubule epithelial cell	3 studies	95% ± 5%	Explore
neural crest cell	3 studies	30% ± 12%	Explore
OFF-bipolar cell	3 studies	61% ± 21%	Explore
ON-bipolar cell	3 studies	63% ± 23%	Explore
retinal ganglion cell	3 studies	81% ± 13%	Explore
kidney loop of Henle epithelial cell	3 studies	93% ± 5%	Explore
renal principal cell	3 studies	97% ± 3%	Explore
common myeloid progenitor	3 studies	65% ± 30%	Explore
pro-B cell	3 studies	87% ± 16%	Explore
neuroendocrine cell	3 studies	77% ± 8%	Explore
mucus secreting cell	3 studies	39% ± 13%	Explore
serous secreting cell	3 studies	39% ± 17%	Explore
Mueller cell	3 studies	48% ± 18%	Explore
amacrine cell	3 studies	61% ± 15%	Explore
myoepithelial cell	3 studies	61% ± 25%	Explore
granulocyte	3 studies	49% ± 21%	Explore
luminal cell of prostate epithelium	3 studies	32% ± 1%	Explore
intermediate monocyte	3 studies	83% ± 5%	Explore
group 3 innate lymphoid cell	3 studies	81% ± 4%	Explore
melanocyte	3 studies	74% ± 15%	Explore
T-helper 1 cell	3 studies	82% ± 23%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	76% ± 25%	Explore
double-positive, alpha-beta thymocyte	3 studies	88% ± 14%	Explore
interneuron	3 studies	72% ± 19%	Explore
progenitor cell of mammary luminal epithelium	3 studies	66% ± 25%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	16 studies	57% ± 22%	Explore
peripheral blood	15 studies	82% ± 14%	Explore
intestine	13 studies	42% ± 22%	Explore
brain	11 studies	35% ± 22%	Explore
liver	7 studies	49% ± 23%	Explore
kidney	7 studies	58% ± 25%	Explore
bone marrow	6 studies	54% ± 34%	Explore
eye	5 studies	57% ± 19%	Explore
breast	4 studies	62% ± 19%	Explore
uterus	3 studies	74% ± 15%	Explore
prostate	3 studies	29% ± 3%	Explore
skin	3 studies	48% ± 14%	Explore
lymph node	3 studies	84% ± 15%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
stomach	99%	162790.91	357 / 359	98%	11140.30	281 / 286
adrenal gland	100%	219015.28	258 / 258	97%	11482.95	224 / 230
brain	100%	241258.16	2630 / 2642	97%	8349.03	687 / 705
esophagus	97%	117639.54	1398 / 1445	100%	8316.15	183 / 183
kidney	97%	274592.75	86 / 89	98%	12185.00	884 / 901
intestine	98%	141242.92	942 / 966	97%	8792.73	511 / 527
skin	97%	78384.86	1761 / 1809	97%	6914.58	457 / 472
prostate	98%	132550.14	240 / 245	92%	7674.69	462 / 502
breast	97%	115990.73	447 / 459	93%	5409.58	1035 / 1118
pancreas	96%	68932.28	316 / 328	93%	6483.87	165 / 178
bladder	95%	115393.14	20 / 21	91%	7188.74	457 / 504
liver	100%	284504.56	225 / 226	86%	6507.20	350 / 406
lung	88%	66293.86	509 / 578	93%	5640.73	1075 / 1155
thymus	90%	91666.29	585 / 653	88%	6138.53	533 / 605
ovary	67%	47051.88	120 / 180	100%	8860.15	429 / 430
uterus	88%	57788.44	149 / 170	78%	3825.36	358 / 459
eye	0%	0	0 / 0	100%	11727.05	80 / 80
heart	100%	383411.19	861 / 861	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	18025.53	1 / 1
muscle	100%	192059.47	801 / 803	0%	0	0 / 0
adipose	97%	122764.74	1172 / 1204	0%	0	0 / 0
spleen	84%	54518.20	202 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	73%	2452.96	33 / 45
blood vessel	69%	42234.60	918 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	59%	2505.22	17 / 29
peripheral blood	22%	14772.68	200 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0009060	Biological process	aerobic respiration
GO_0006120	Biological process	mitochondrial electron transport, NADH to ubiquinone
GO_0042776	Biological process	proton motive force-driven mitochondrial ATP synthesis
GO_0055085	Biological process	transmembrane transport
GO_0045271	Cellular component	respiratory chain complex I
GO_0005743	Cellular component	mitochondrial inner membrane
GO_0008137	Molecular function	NADH dehydrogenase (ubiquinone) activity

Gene name	MT-ND4L
Protein name	NADH-ubiquinone oxidoreductase chain 4L (EC 7.1.1.2) (NADH dehydrogenase subunit 4L) (ND4L)
Synonyms	MTND4L NADH4L ND4L
Description	FUNCTION: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor . Part of the enzyme membrane arm which is embedded in the lipid bilayer and involved in proton translocation . .
Accessions	ENST00000361335.1 P03901

MT-ND4L report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review