BTG2 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
B cell	41 studies	45% ± 15%	Explore
natural killer cell	35 studies	41% ± 17%	Explore
fibroblast	35 studies	38% ± 19%	Explore
macrophage	32 studies	33% ± 14%	Explore
endothelial cell	32 studies	35% ± 18%	Explore
CD8-positive, alpha-beta T cell	31 studies	39% ± 15%	Explore
pericyte	29 studies	45% ± 23%	Explore
T cell	27 studies	43% ± 21%	Explore
conventional dendritic cell	27 studies	38% ± 12%	Explore
CD4-positive, alpha-beta T cell	27 studies	46% ± 16%	Explore
plasma cell	26 studies	52% ± 19%	Explore
smooth muscle cell	25 studies	46% ± 21%	Explore
regulatory T cell	25 studies	44% ± 18%	Explore
classical monocyte	24 studies	35% ± 15%	Explore
non-classical monocyte	23 studies	38% ± 15%	Explore
plasmacytoid dendritic cell	22 studies	59% ± 17%	Explore
mast cell	21 studies	55% ± 20%	Explore
basal cell	21 studies	37% ± 16%	Explore
memory B cell	20 studies	46% ± 13%	Explore
naive B cell	20 studies	46% ± 12%	Explore
gamma-delta T cell	19 studies	42% ± 18%	Explore
mature NK T cell	18 studies	40% ± 17%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	18 studies	35% ± 12%	Explore
CD16-negative, CD56-bright natural killer cell, human	17 studies	40% ± 21%	Explore
epithelial cell	17 studies	44% ± 22%	Explore
monocyte	16 studies	38% ± 19%	Explore
endothelial cell of lymphatic vessel	14 studies	31% ± 12%	Explore
mucosal invariant T cell	14 studies	44% ± 17%	Explore
connective tissue cell	14 studies	34% ± 17%	Explore
CD16-positive, CD56-dim natural killer cell, human	14 studies	41% ± 17%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	13 studies	34% ± 13%	Explore
myofibroblast cell	13 studies	41% ± 19%	Explore
CD4-positive, alpha-beta memory T cell	12 studies	40% ± 20%	Explore
endothelial cell of vascular tree	12 studies	38% ± 20%	Explore
ciliated cell	12 studies	46% ± 23%	Explore
dendritic cell	11 studies	41% ± 19%	Explore
effector memory CD8-positive, alpha-beta T cell	11 studies	38% ± 15%	Explore
innate lymphoid cell	10 studies	41% ± 17%	Explore
CD8-positive, alpha-beta memory T cell	10 studies	46% ± 20%	Explore
neutrophil	10 studies	44% ± 16%	Explore
endothelial cell of artery	10 studies	38% ± 11%	Explore
goblet cell	10 studies	40% ± 16%	Explore
microglial cell	10 studies	34% ± 20%	Explore
abnormal cell	10 studies	36% ± 15%	Explore
vein endothelial cell	10 studies	29% ± 9%	Explore
leukocyte	9 studies	40% ± 15%	Explore
capillary endothelial cell	9 studies	29% ± 8%	Explore
IgG plasma cell	9 studies	52% ± 15%	Explore
myeloid cell	9 studies	42% ± 18%	Explore
type I pneumocyte	8 studies	36% ± 17%	Explore
plasmablast	8 studies	49% ± 12%	Explore
progenitor cell	8 studies	32% ± 11%	Explore
IgA plasma cell	8 studies	48% ± 14%	Explore
T follicular helper cell	8 studies	52% ± 21%	Explore
secretory cell	8 studies	41% ± 23%	Explore
type II pneumocyte	7 studies	35% ± 15%	Explore
effector CD8-positive, alpha-beta T cell	7 studies	31% ± 9%	Explore
precursor B cell	7 studies	62% ± 18%	Explore
CD4-positive helper T cell	6 studies	42% ± 17%	Explore
enteroendocrine cell	6 studies	37% ± 19%	Explore
immature B cell	6 studies	61% ± 13%	Explore
mesothelial cell	6 studies	40% ± 23%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	40% ± 15%	Explore
erythrocyte	6 studies	31% ± 14%	Explore
central memory CD8-positive, alpha-beta T cell	5 studies	29% ± 4%	Explore
club cell	5 studies	41% ± 13%	Explore
ionocyte	5 studies	40% ± 18%	Explore
effector CD4-positive, alpha-beta T cell	5 studies	36% ± 15%	Explore
mononuclear phagocyte	5 studies	39% ± 12%	Explore
kidney distal convoluted tubule epithelial cell	5 studies	42% ± 11%	Explore
intestinal crypt stem cell	5 studies	33% ± 14%	Explore
renal principal cell	5 studies	53% ± 17%	Explore
hematopoietic stem cell	5 studies	26% ± 11%	Explore
pro-B cell	5 studies	48% ± 8%	Explore
brush cell	5 studies	35% ± 21%	Explore
enterocyte	5 studies	27% ± 9%	Explore
group 3 innate lymphoid cell	5 studies	74% ± 15%	Explore
adipocyte	5 studies	24% ± 11%	Explore
hematopoietic precursor cell	4 studies	38% ± 13%	Explore
pancreatic A cell	4 studies	49% ± 21%	Explore
exhausted T cell	4 studies	27% ± 9%	Explore
kidney loop of Henle epithelial cell	4 studies	28% ± 12%	Explore
T-helper 17 cell	4 studies	59% ± 21%	Explore
retinal pigment epithelial cell	4 studies	33% ± 8%	Explore
adventitial cell	4 studies	42% ± 22%	Explore
acinar cell	4 studies	45% ± 23%	Explore
germinal center B cell	4 studies	32% ± 10%	Explore
intermediate monocyte	4 studies	43% ± 17%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	56% ± 24%	Explore
granulocyte	4 studies	58% ± 20%	Explore
IgM plasma cell	4 studies	42% ± 15%	Explore
glial cell	4 studies	24% ± 6%	Explore
keratinocyte	4 studies	42% ± 24%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	22% ± 4%	Explore
pancreatic D cell	3 studies	53% ± 22%	Explore
kidney connecting tubule epithelial cell	3 studies	68% ± 17%	Explore
podocyte	3 studies	59% ± 16%	Explore
renal alpha-intercalated cell	3 studies	42% ± 9%	Explore
astrocyte	3 studies	34% ± 8%	Explore
neuroendocrine cell	3 studies	49% ± 22%	Explore
cardiac muscle cell	3 studies	18% ± 3%	Explore
Mueller cell	3 studies	52% ± 9%	Explore
oligodendrocyte precursor cell	3 studies	21% ± 5%	Explore
T-helper 1 cell	3 studies	54% ± 17%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	43% ± 8%	Explore
double negative thymocyte	3 studies	55% ± 21%	Explore
double-positive, alpha-beta thymocyte	3 studies	62% ± 24%	Explore
CD4-positive, alpha-beta cytotoxic T cell	3 studies	27% ± 5%	Explore
transit amplifying cell	3 studies	20% ± 4%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	18 studies	36% ± 14%	Explore
lung	16 studies	37% ± 14%	Explore
intestine	13 studies	36% ± 16%	Explore
kidney	7 studies	32% ± 8%	Explore
lymph node	6 studies	47% ± 14%	Explore
bone marrow	5 studies	31% ± 9%	Explore
eye	5 studies	25% ± 13%	Explore
uterus	5 studies	55% ± 18%	Explore
liver	5 studies	36% ± 16%	Explore
pancreas	4 studies	45% ± 15%	Explore
prostate	4 studies	24% ± 2%	Explore
breast	4 studies	41% ± 7%	Explore
adrenal gland	3 studies	42% ± 17%	Explore
esophagus	3 studies	33% ± 9%	Explore
brain	3 studies	27% ± 4%	Explore
skin	3 studies	35% ± 17%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
prostate	100%	17315.97	244 / 245	99%	417.02	495 / 502
stomach	100%	28019.32	359 / 359	97%	170.81	277 / 286
breast	100%	16159.54	457 / 459	96%	371.96	1068 / 1118
bladder	100%	28359.67	21 / 21	94%	272.38	473 / 504
intestine	97%	23481.60	939 / 966	96%	163.59	506 / 527
lung	98%	14117.61	567 / 578	94%	175.66	1083 / 1155
pancreas	100%	33069.71	327 / 328	92%	164.96	164 / 178
thymus	91%	9469.59	597 / 653	100%	425.91	602 / 605
ovary	98%	32382.27	177 / 180	89%	140.51	384 / 430
kidney	91%	10542.48	81 / 89	89%	139.20	800 / 901
uterus	89%	9790.70	151 / 170	90%	163.14	411 / 459
esophagus	91%	17484.12	1311 / 1445	85%	139.37	156 / 183
brain	46%	2976.91	1225 / 2642	99%	223.71	700 / 705
adrenal gland	63%	8057.63	163 / 258	75%	264.06	173 / 230
skin	76%	11121.79	1370 / 1809	42%	39.56	196 / 472
lymph node	0%	0	0 / 0	100%	385.18	29 / 29
spleen	100%	14466.78	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	236.20	1 / 1
adipose	99%	19625.99	1195 / 1204	0%	0	0 / 0
blood vessel	99%	24969.94	1321 / 1335	0%	0	0 / 0
tonsil	0%	0	0 / 0	96%	159.75	43 / 45
muscle	93%	15065.50	743 / 803	0%	0	0 / 0
heart	90%	17549.45	774 / 861	0%	0	0 / 0
peripheral blood	79%	8562.19	734 / 929	0%	0	0 / 0
liver	3%	116.05	6 / 226	29%	28.40	117 / 406
eye	0%	0	0 / 0	11%	6.44	9 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0008285	Biological process	negative regulation of cell population proliferation
GO_0006281	Biological process	DNA repair
GO_0043434	Biological process	response to peptide hormone
GO_0051602	Biological process	response to electrical stimulus
GO_0031175	Biological process	neuron projection development
GO_0060213	Biological process	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
GO_0006974	Biological process	DNA damage response
GO_0021542	Biological process	dentate gyrus development
GO_0014070	Biological process	response to organic cyclic compound
GO_0008306	Biological process	associative learning
GO_0000122	Biological process	negative regulation of transcription by RNA polymerase II
GO_0021954	Biological process	central nervous system neuron development
GO_0009952	Biological process	anterior/posterior pattern specification
GO_0009612	Biological process	response to mechanical stimulus
GO_0035914	Biological process	skeletal muscle cell differentiation
GO_0045930	Biological process	negative regulation of mitotic cell cycle
GO_0043524	Biological process	negative regulation of neuron apoptotic process
GO_0017148	Biological process	negative regulation of translation
GO_0007405	Biological process	neuroblast proliferation
GO_0007406	Biological process	negative regulation of neuroblast proliferation
GO_0070062	Cellular component	extracellular exosome
GO_0005634	Cellular component	nucleus
GO_0005829	Cellular component	cytosol
GO_0005737	Cellular component	cytoplasm
GO_0003714	Molecular function	transcription corepressor activity
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	BTG2
Protein name	Protein BTG2 (BTG family member 2) (NGF-inducible anti-proliferative protein PC3)
Synonyms	PC3
Description	FUNCTION: Anti-proliferative protein; the function is mediated by association with deadenylase subunits of the CCR4-NOT complex. Activates mRNA deadenylation in a CNOT6 and CNOT7-dependent manner. In vitro can inhibit deadenylase activity of CNOT7 and CNOT8. Involved in cell cycle regulation. Could be involved in the growth arrest and differentiation of the neuronal precursors (By similarity). Modulates transcription regulation mediated by ESR1. Involved in mitochondrial depolarization and neurite outgrowth. .
Accessions	ENST00000475157.1 P78543 ENST00000290551.5

BTG2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review