GO_0000956 | nuclear-transcribed mRNA catabolic process | OmnibusX

nuclear-transcribed mRNA catabolic process

I. Involved cell types

	Genes	Cell types	No. of supported studies
Group 1	DHX34 UPF1 LSM7 XRN2 NBDY SKIC3 EXOSC7 XRN1 NBAS DIS3L2 AGO1 EXOSC10 RC3H1 THRAP3	dopaminergic neuron	5 studies
Group 2	EXOSC5 LSM4 DDX5 POLR2G	myeloid cell B cell epithelial cell hematopoietic stem cell	8 studies
Group 3	EXOSC6 EXOSC8 EXOSC3 EXOSC4 MRTO4	epithelial cell	6 studies
Group 4	EXOSC2	B cell epithelial cell hematopoietic stem cell	3 studies
Group 5	EXOSC9	hematopoietic stem cell B cell lymphocyte	8 studies

II. Literature review

Name	nuclear-transcribed mRNA catabolic process
ID	GO_0000956
collection_id	Biological process
Exact synonym	nuclear mRNA breakdown, nuclear mRNA catabolism, nuclear mRNA degradation
Description	The chemical reactions and pathways resulting in the breakdown of nuclear-transcribed mRNAs in eukaryotic cells.
External URL
Genes	DDX5 POLR2G DIS3L2 LSM7 EXOSC9 XRN2 MRTO4 AGO1 SKIC3 LSM4 DHX34 EXOSC5 EXOSC10 EXOSC6 RC3H1 EXOSC4 EXOSC7 EXOSC3 NBAS EXOSC2 XRN1 DXO NBDY UPF1 EXOSC8 THRAP3