SSU72 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
B cell	31 studies	27% ± 10%	Explore
natural killer cell	31 studies	27% ± 8%	Explore
endothelial cell	30 studies	26% ± 12%	Explore
CD8-positive, alpha-beta T cell	28 studies	26% ± 9%	Explore
fibroblast	26 studies	26% ± 11%	Explore
CD4-positive, alpha-beta T cell	26 studies	28% ± 9%	Explore
T cell	23 studies	26% ± 8%	Explore
pericyte	22 studies	26% ± 7%	Explore
macrophage	22 studies	25% ± 10%	Explore
classical monocyte	22 studies	29% ± 13%	Explore
non-classical monocyte	21 studies	31% ± 16%	Explore
regulatory T cell	21 studies	28% ± 7%	Explore
smooth muscle cell	20 studies	23% ± 7%	Explore
conventional dendritic cell	20 studies	33% ± 16%	Explore
memory B cell	19 studies	27% ± 7%	Explore
basal cell	19 studies	30% ± 16%	Explore
naive B cell	18 studies	25% ± 6%	Explore
gamma-delta T cell	17 studies	29% ± 12%	Explore
ciliated cell	16 studies	41% ± 17%	Explore
epithelial cell	16 studies	35% ± 21%	Explore
monocyte	15 studies	28% ± 10%	Explore
mature NK T cell	14 studies	26% ± 8%	Explore
CD16-positive, CD56-dim natural killer cell, human	13 studies	28% ± 8%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	13 studies	28% ± 8%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	13 studies	32% ± 10%	Explore
mast cell	12 studies	24% ± 4%	Explore
endothelial cell of lymphatic vessel	12 studies	26% ± 8%	Explore
dendritic cell	12 studies	33% ± 25%	Explore
capillary endothelial cell	12 studies	23% ± 3%	Explore
plasmacytoid dendritic cell	11 studies	27% ± 10%	Explore
CD16-negative, CD56-bright natural killer cell, human	11 studies	27% ± 7%	Explore
mucosal invariant T cell	11 studies	25% ± 6%	Explore
CD4-positive, alpha-beta memory T cell	10 studies	28% ± 9%	Explore
secretory cell	10 studies	28% ± 14%	Explore
endothelial cell of artery	10 studies	23% ± 6%	Explore
vein endothelial cell	10 studies	20% ± 4%	Explore
myeloid cell	10 studies	29% ± 14%	Explore
plasma cell	9 studies	34% ± 14%	Explore
CD8-positive, alpha-beta memory T cell	9 studies	34% ± 8%	Explore
effector memory CD8-positive, alpha-beta T cell	9 studies	33% ± 12%	Explore
connective tissue cell	9 studies	25% ± 8%	Explore
plasmablast	8 studies	39% ± 24%	Explore
type I pneumocyte	7 studies	26% ± 13%	Explore
type II pneumocyte	7 studies	32% ± 18%	Explore
goblet cell	7 studies	27% ± 12%	Explore
abnormal cell	7 studies	33% ± 11%	Explore
T follicular helper cell	7 studies	33% ± 6%	Explore
endothelial cell of vascular tree	7 studies	27% ± 7%	Explore
alveolar macrophage	6 studies	25% ± 6%	Explore
hematopoietic precursor cell	6 studies	39% ± 17%	Explore
club cell	6 studies	33% ± 11%	Explore
respiratory goblet cell	6 studies	34% ± 20%	Explore
leukocyte	6 studies	26% ± 8%	Explore
neuron	6 studies	31% ± 16%	Explore
enterocyte	6 studies	21% ± 5%	Explore
myofibroblast cell	6 studies	24% ± 4%	Explore
hematopoietic stem cell	6 studies	22% ± 7%	Explore
innate lymphoid cell	6 studies	26% ± 3%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	31% ± 15%	Explore
exhausted T cell	5 studies	31% ± 14%	Explore
ionocyte	5 studies	27% ± 9%	Explore
effector CD8-positive, alpha-beta T cell	5 studies	20% ± 2%	Explore
mononuclear phagocyte	5 studies	31% ± 17%	Explore
kidney loop of Henle epithelial cell	5 studies	24% ± 4%	Explore
intestinal crypt stem cell	5 studies	21% ± 7%	Explore
mesothelial cell	5 studies	32% ± 17%	Explore
progenitor cell	5 studies	22% ± 5%	Explore
transit amplifying cell	5 studies	22% ± 4%	Explore
pro-B cell	5 studies	23% ± 4%	Explore
microglial cell	5 studies	23% ± 8%	Explore
squamous epithelial cell	4 studies	36% ± 25%	Explore
epithelial cell of proximal tubule	4 studies	25% ± 5%	Explore
glutamatergic neuron	4 studies	36% ± 20%	Explore
retinal ganglion cell	4 studies	70% ± 26%	Explore
precursor B cell	4 studies	23% ± 5%	Explore
immature B cell	4 studies	22% ± 3%	Explore
astrocyte	4 studies	25% ± 14%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	22% ± 2%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	33% ± 4%	Explore
oligodendrocyte precursor cell	4 studies	21% ± 5%	Explore
neutrophil	4 studies	18% ± 1%	Explore
enteroendocrine cell	4 studies	35% ± 19%	Explore
hepatocyte	4 studies	35% ± 25%	Explore
T-helper 17 cell	4 studies	25% ± 6%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	25% ± 7%	Explore
deuterosomal cell	3 studies	25% ± 12%	Explore
duct epithelial cell	3 studies	31% ± 9%	Explore
pancreatic A cell	3 studies	55% ± 20%	Explore
type B pancreatic cell	3 studies	50% ± 19%	Explore
glomerular endothelial cell	3 studies	20% ± 3%	Explore
neural crest cell	3 studies	21% ± 0%	Explore
retinal bipolar neuron	3 studies	44% ± 16%	Explore
extravillous trophoblast	3 studies	30% ± 10%	Explore
placental villous trophoblast	3 studies	39% ± 11%	Explore
common myeloid progenitor	3 studies	33% ± 19%	Explore
lymphocyte	3 studies	29% ± 12%	Explore
megakaryocyte	3 studies	22% ± 5%	Explore
brush cell	3 studies	30% ± 10%	Explore
neuroendocrine cell	3 studies	38% ± 9%	Explore
amacrine cell	3 studies	45% ± 14%	Explore
retina horizontal cell	3 studies	42% ± 16%	Explore
retinal rod cell	3 studies	27% ± 9%	Explore
serous secreting cell	3 studies	42% ± 12%	Explore
intraepithelial lymphocyte	3 studies	26% ± 7%	Explore
Mueller cell	3 studies	27% ± 6%	Explore
germinal center B cell	3 studies	29% ± 3%	Explore
CD4-positive helper T cell	3 studies	26% ± 8%	Explore
muscle cell	3 studies	26% ± 16%	Explore
GABAergic neuron	3 studies	32% ± 12%	Explore
granulocyte	3 studies	27% ± 7%	Explore
granulocyte monocyte progenitor cell	3 studies	30% ± 14%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	42% ± 27%	Explore
erythrocyte	3 studies	31% ± 9%	Explore
group 3 innate lymphoid cell	3 studies	33% ± 10%	Explore
keratinocyte	3 studies	28% ± 7%	Explore
T-helper 1 cell	3 studies	30% ± 10%	Explore
erythroblast	3 studies	36% ± 18%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	27% ± 7%	Explore
central memory CD8-positive, alpha-beta T cell	3 studies	20% ± 4%	Explore
double negative thymocyte	3 studies	36% ± 12%	Explore
progenitor cell of mammary luminal epithelium	3 studies	28% ± 1%	Explore
luminal cell of prostate epithelium	3 studies	24% ± 7%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	17 studies	31% ± 12%	Explore
peripheral blood	16 studies	32% ± 12%	Explore
intestine	10 studies	25% ± 10%	Explore
eye	8 studies	26% ± 12%	Explore
kidney	6 studies	22% ± 5%	Explore
brain	6 studies	28% ± 10%	Explore
liver	6 studies	28% ± 15%	Explore
bone marrow	4 studies	23% ± 6%	Explore
uterus	4 studies	32% ± 15%	Explore
breast	4 studies	26% ± 2%	Explore
lymph node	4 studies	28% ± 8%	Explore
pancreas	3 studies	49% ± 24%	Explore
placenta	3 studies	31% ± 11%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	6004.24	1445 / 1445	100%	48.48	183 / 183
intestine	100%	6319.39	966 / 966	100%	58.25	527 / 527
kidney	100%	6535.63	89 / 89	100%	37.62	901 / 901
liver	100%	4754.49	226 / 226	100%	40.68	406 / 406
ovary	100%	5528.72	180 / 180	100%	78.07	430 / 430
pancreas	100%	4463.29	328 / 328	100%	57.64	178 / 178
prostate	100%	6604.26	245 / 245	100%	77.68	502 / 502
skin	100%	6577.26	1809 / 1809	100%	79.18	472 / 472
stomach	100%	5300.07	359 / 359	100%	50.85	286 / 286
thymus	100%	8347.07	653 / 653	100%	73.01	605 / 605
uterus	100%	5586.68	170 / 170	100%	69.81	459 / 459
brain	100%	6194.50	2640 / 2642	100%	52.52	705 / 705
lung	100%	6744.68	578 / 578	100%	59.20	1154 / 1155
breast	100%	7000.54	459 / 459	100%	63.84	1114 / 1118
bladder	100%	5663.48	21 / 21	99%	65.11	500 / 504
adrenal gland	100%	6177.82	258 / 258	99%	39.94	228 / 230
adipose	100%	6692.25	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	175.19	80 / 80
lymph node	0%	0	0 / 0	100%	74.15	29 / 29
muscle	100%	8967.79	803 / 803	0%	0	0 / 0
spleen	100%	7740.05	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	57.08	45 / 45
ureter	0%	0	0 / 0	100%	75.76	1 / 1
blood vessel	100%	4911.15	1334 / 1335	0%	0	0 / 0
heart	100%	4875.53	859 / 861	0%	0	0 / 0
peripheral blood	99%	5808.80	918 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0180010	Biological process	co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway
GO_0006369	Biological process	termination of RNA polymerase II transcription
GO_0006357	Biological process	regulation of transcription by RNA polymerase II
GO_0005847	Cellular component	mRNA cleavage and polyadenylation specificity factor complex
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0008420	Molecular function	RNA polymerase II CTD heptapeptide repeat phosphatase activity
GO_0005515	Molecular function	protein binding
GO_0017018	Molecular function	myosin phosphatase activity

Gene name	SSU72
Protein name	RNA polymerase II subunit A C-terminal domain phosphatase SSU72 (CTD phosphatase SSU72) (EC 3.1.3.16)
Synonyms	HSPC182 PNAS-120
Description	FUNCTION: Protein phosphatase that catalyzes the dephosphorylation of the C-terminal domain of RNA polymerase II. Plays a role in RNA processing and termination. Plays a role in pre-mRNA polyadenylation via its interaction with SYMPK. .
Accessions	ENST00000359060.5 [Q9NP77-2] Q9NP77 ENST00000291386.4 [Q9NP77-1]

SSU72 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review