mRNA cleavage and polyadenylation specificity factor complex

I. Literature review

[source]
NamemRNA cleavage and polyadenylation specificity factor complex
IDGO_0005847
collection_id

Cellular component

Related synonym

CFII complex, cleavage and polyadenylylation specificity factor activity

Description

A multisubunit complex that binds to the canonical AAUAAA hexamer and to U-rich upstream sequence elements on the pre-mRNA, thereby stimulating the otherwise weakly active and nonspecific polymerase to elongate efficiently RNAs containing a poly(A) signal.

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Genes