ZC3H3 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ZC3H3 at tissue level.

III. Associated gene sets

GO_0031124Biological processmRNA 3'-end processing
GO_0032927Biological processpositive regulation of activin receptor signaling pathway
GO_0051028Biological processmRNA transport
GO_0005847Cellular componentmRNA cleavage and polyadenylation specificity factor complex
GO_0005634Cellular componentnucleus
GO_0003677Molecular functionDNA binding
GO_0070412Molecular functionR-SMAD binding
GO_0046872Molecular functionmetal ion binding
GO_0003674Molecular functionmolecular_function

IV. Literature review

[source]
Gene nameZC3H3
Protein nameZinc finger CCCH domain-containing protein 3 (Smad-interacting CPSF-like factor)
Zinc finger CCCH-type containing 3
Zinc finger CCCH domain-containing protein 3
SynonymsZC3HDC3
SMICL
KIAA0150
DescriptionFUNCTION: Required for the export of polyadenylated mRNAs from the nucleus . Enhances ACVR1B-induced SMAD-dependent transcription. Binds to single-stranded DNA but not to double-stranded DNA in vitro. Involved in RNA cleavage (By similarity). .

AccessionsQ8IXZ2
ENST00000262577.6 [Q8IXZ2-1]
ENST00000632165.1
ENST00000528401.1
A0A0J9YYE2
H0YEY2