Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| epithelial cell | 3 studies | 23% ± 7% | |
| astrocyte | 3 studies | 20% ± 2% |
Insufficient scRNA-seq data for expression of ZC3H3 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 1920.68 | 1445 / 1445 | 100% | 61.44 | 183 / 183 |
| ovary | 100% | 1853.63 | 180 / 180 | 100% | 69.48 | 430 / 430 |
| uterus | 100% | 1977.80 | 170 / 170 | 100% | 32.99 | 459 / 459 |
| thymus | 100% | 2425.82 | 653 / 653 | 100% | 29.84 | 603 / 605 |
| intestine | 100% | 2257.59 | 966 / 966 | 99% | 36.74 | 524 / 527 |
| prostate | 100% | 2037.76 | 245 / 245 | 99% | 27.43 | 499 / 502 |
| skin | 100% | 2183.56 | 1809 / 1809 | 99% | 42.96 | 469 / 472 |
| adrenal gland | 100% | 1912.61 | 258 / 258 | 99% | 21.73 | 228 / 230 |
| breast | 100% | 2374.26 | 459 / 459 | 99% | 36.56 | 1108 / 1118 |
| kidney | 100% | 3278.09 | 89 / 89 | 99% | 21.62 | 892 / 901 |
| stomach | 100% | 1478.79 | 359 / 359 | 99% | 41.95 | 283 / 286 |
| lung | 100% | 2346.47 | 578 / 578 | 99% | 33.80 | 1141 / 1155 |
| liver | 100% | 3569.27 | 226 / 226 | 98% | 28.52 | 399 / 406 |
| bladder | 100% | 1950.00 | 21 / 21 | 98% | 34.28 | 495 / 504 |
| brain | 98% | 1203.73 | 2596 / 2642 | 100% | 27.80 | 702 / 705 |
| pancreas | 98% | 940.21 | 321 / 328 | 99% | 27.16 | 176 / 178 |
| adipose | 100% | 2527.78 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 61.19 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 32.46 | 29 / 29 |
| muscle | 100% | 1933.34 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 2944.09 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 31.59 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 52.50 | 1 / 1 |
| blood vessel | 100% | 1700.31 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| peripheral blood | 100% | 3623.07 | 926 / 929 | 0% | 0 | 0 / 0 |
| heart | 98% | 1024.80 | 843 / 861 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0031124 | Biological process | mRNA 3'-end processing |
| GO_0032927 | Biological process | positive regulation of activin receptor signaling pathway |
| GO_0051028 | Biological process | mRNA transport |
| GO_0005847 | Cellular component | mRNA cleavage and polyadenylation specificity factor complex |
| GO_0005634 | Cellular component | nucleus |
| GO_0003677 | Molecular function | DNA binding |
| GO_0070412 | Molecular function | R-SMAD binding |
| GO_0046872 | Molecular function | metal ion binding |
| GO_0003674 | Molecular function | molecular_function |
| Gene name | ZC3H3 |
| Protein name | Zinc finger CCCH domain-containing protein 3 (Smad-interacting CPSF-like factor) Zinc finger CCCH-type containing 3 Zinc finger CCCH domain-containing protein 3 |
| Synonyms | ZC3HDC3 SMICL KIAA0150 |
| Description | FUNCTION: Required for the export of polyadenylated mRNAs from the nucleus . Enhances ACVR1B-induced SMAD-dependent transcription. Binds to single-stranded DNA but not to double-stranded DNA in vitro. Involved in RNA cleavage (By similarity). . |
| Accessions | Q8IXZ2 ENST00000262577.6 [Q8IXZ2-1] ENST00000632165.1 ENST00000528401.1 A0A0J9YYE2 H0YEY2 |