FIP1L1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	13 studies	22% ± 4%	Explore
endothelial cell	12 studies	28% ± 11%	Explore
regulatory T cell	11 studies	20% ± 4%	Explore
oligodendrocyte precursor cell	10 studies	44% ± 16%	Explore
CD8-positive, alpha-beta T cell	10 studies	21% ± 5%	Explore
plasmacytoid dendritic cell	10 studies	25% ± 6%	Explore
fibroblast	10 studies	25% ± 5%	Explore
B cell	9 studies	20% ± 5%	Explore
CD16-negative, CD56-bright natural killer cell, human	9 studies	21% ± 3%	Explore
naive B cell	8 studies	20% ± 3%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	8 studies	18% ± 3%	Explore
CD16-positive, CD56-dim natural killer cell, human	8 studies	22% ± 4%	Explore
CD4-positive, alpha-beta T cell	8 studies	19% ± 5%	Explore
oligodendrocyte	8 studies	27% ± 9%	Explore
gamma-delta T cell	8 studies	23% ± 10%	Explore
microglial cell	7 studies	27% ± 9%	Explore
memory B cell	7 studies	18% ± 2%	Explore
mucosal invariant T cell	7 studies	18% ± 1%	Explore
astrocyte	7 studies	32% ± 14%	Explore
GABAergic neuron	6 studies	42% ± 23%	Explore
glutamatergic neuron	6 studies	49% ± 28%	Explore
effector memory CD8-positive, alpha-beta T cell	5 studies	21% ± 2%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	5 studies	18% ± 1%	Explore
interneuron	5 studies	37% ± 23%	Explore
macrophage	5 studies	25% ± 9%	Explore
epithelial cell	5 studies	33% ± 16%	Explore
retina horizontal cell	5 studies	27% ± 8%	Explore
exhausted T cell	4 studies	21% ± 6%	Explore
mature NK T cell	4 studies	19% ± 2%	Explore
precursor B cell	4 studies	29% ± 8%	Explore
myofibroblast cell	4 studies	23% ± 10%	Explore
immature B cell	4 studies	23% ± 6%	Explore
ciliated cell	4 studies	25% ± 8%	Explore
T follicular helper cell	4 studies	17% ± 1%	Explore
CD8-positive, alpha-beta memory T cell	4 studies	24% ± 3%	Explore
T cell	4 studies	21% ± 3%	Explore
leukocyte	3 studies	18% ± 2%	Explore
conventional dendritic cell	3 studies	31% ± 13%	Explore
non-classical monocyte	3 studies	20% ± 4%	Explore
GABAergic interneuron	3 studies	21% ± 5%	Explore
neuron	3 studies	33% ± 15%	Explore
connective tissue cell	3 studies	25% ± 2%	Explore
pro-B cell	3 studies	31% ± 5%	Explore
amacrine cell	3 studies	30% ± 3%	Explore
GABAergic amacrine cell	3 studies	26% ± 6%	Explore
glycinergic amacrine cell	3 studies	20% ± 2%	Explore
rod bipolar cell	3 studies	21% ± 3%	Explore
dendritic cell	3 studies	34% ± 13%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	20% ± 4%	Explore
group 3 innate lymphoid cell	3 studies	24% ± 7%	Explore
mast cell	3 studies	18% ± 2%	Explore
smooth muscle cell	3 studies	15% ± 0%	Explore
double negative thymocyte	3 studies	30% ± 10%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	10 studies	36% ± 21%	Explore
peripheral blood	5 studies	21% ± 6%	Explore
lung	4 studies	21% ± 4%	Explore
eye	3 studies	18% ± 1%	Explore
intestine	3 studies	21% ± 7%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
lung	100%	1743.56	578 / 578	100%	9.01	1154 / 1155
breast	100%	1974.77	459 / 459	100%	11.20	1117 / 1118
brain	100%	1334.13	2636 / 2642	100%	13.68	705 / 705
prostate	100%	1542.70	245 / 245	100%	7.65	500 / 502
esophagus	100%	1549.32	1445 / 1445	99%	6.56	182 / 183
intestine	100%	1643.08	966 / 966	99%	8.61	524 / 527
bladder	100%	1937.48	21 / 21	99%	9.58	501 / 504
thymus	100%	1729.91	653 / 653	99%	9.82	601 / 605
ovary	100%	2494.21	180 / 180	99%	6.02	426 / 430
stomach	100%	1283.81	359 / 359	99%	7.01	283 / 286
uterus	100%	2026.82	170 / 170	99%	10.97	454 / 459
skin	100%	2480.75	1809 / 1809	99%	11.96	466 / 472
pancreas	99%	767.32	325 / 328	99%	8.21	176 / 178
kidney	100%	1296.55	89 / 89	97%	6.08	875 / 901
adrenal gland	100%	1960.84	258 / 258	97%	5.87	223 / 230
liver	100%	774.93	226 / 226	93%	4.62	377 / 406
adipose	100%	1993.72	1204 / 1204	0%	0	0 / 0
blood vessel	100%	2041.05	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	10.69	29 / 29
muscle	100%	1591.88	803 / 803	0%	0	0 / 0
spleen	100%	1860.99	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	9.96	45 / 45
ureter	0%	0	0 / 0	100%	4.17	1 / 1
peripheral blood	98%	1792.25	912 / 929	0%	0	0 / 0
heart	97%	1113.99	832 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	90%	5.06	72 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0006397	Biological process	mRNA processing
GO_0005847	Cellular component	mRNA cleavage and polyadenylation specificity factor complex
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0005515	Molecular function	protein binding
GO_0003723	Molecular function	RNA binding

IV. Literature review

[source]

Gene name	FIP1L1
Protein name	Pre-mRNA 3'-end-processing factor FIP1 (hFip1) (FIP1-like 1 protein) (Factor interacting with PAP) (Rearranged in hypereosinophilia) Factor interacting with PAPOLA and CPSF1 Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1 protein)
Synonyms	FIP1 hCG_21518 RHE
Description	FUNCTION: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. FIP1L1 contributes to poly(A) site recognition and stimulates poly(A) addition. Binds to U-rich RNA sequence elements surrounding the poly(A) site. May act to tether poly(A) polymerase to the CPSF complex. .
Accessions	ENST00000703467.1 A0A994J6Q2 A0A994J6R9 A0A994J6B8 A0A994J3L5 ENST00000703466.1 A0A994J3J1 ENST00000703488.1 ENST00000703457.1 ENST00000703462.1 A0A994J3Q5 A0A994J3T0 A0A994J6R4 ENST00000504094.2 A0A994J3P6 ENST00000703456.1 A0A994J3R5 A0A994J469 A0A994J6E2 A0A994J448 ENST00000703491.1 ENST00000703479.1 A0A994J474 A0A994J3S0 A0A994J6E0 A0A994J458 ENST00000703463.1 A0A994J3L0 ENST00000703458.1 ENST00000703471.1 ENST00000703474.1 ENST00000703465.1 ENST00000703460.1 A0A994J6B4 ENST00000703499.1 A0A994J3J6 A0A994J3K1 A0A994J464 ENST00000703492.1 ENST00000703473.1 A0A994J6Q5 ENST00000703482.1 ENST00000306932.10 [Q6UN15-3] A0A994J3R0 H0Y8P7 ENST00000703478.1 ENST00000703459.1 A0A994J6D3 ENST00000703455.1 ENST00000703464.1 A0A994J3T5 ENST00000514543.5 ENST00000703451.1 ENST00000703475.1 A0A994J6P8 ENST00000703461.1 ENST00000703472.1 A0A994J3Q0 ENST00000703469.1 A0A994J6C6 ENST00000358575.9 [Q6UN15-5] H0Y8J4 A0A994J6D6 ENST00000703454.1 A0A994J6P0 ENST00000703489.1 [Q6UN15-1] A0A994J6C9 ENST00000703500.1 ENST00000337488.11 [Q6UN15-1] ENST00000703483.1 A0A994J6P3 A0A994J453 ENST00000703487.1 ENST00000703498.1 ENST00000507922.5 [Q6UN15-4] A0A994J3K5 ENST00000703481.1 A0A994J442 ENST00000703476.1 A0A994J6C2 Q6UN15 ENST00000703453.1 A0A994J438 A0A994J6N5 ENST00000703468.1 A0A994J6R0 ENST00000703470.1 A0A994J3S6 ENST00000703484.1 A0A994J3M0 A0A994J3I9 A0A994J3M5 ENST00000703480.1 ENST00000703485.1 ENST00000703497.1 ENST00000703490.1 ENST00000703452.1 ENST00000703486.1

FIP1L1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review