CPSF4 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of CPSF4 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CPSF4 at tissue level.

III. Associated gene sets

GO_0006397Biological processmRNA processing
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0005847Cellular componentmRNA cleavage and polyadenylation specificity factor complex
GO_0005654Cellular componentnucleoplasm
GO_1990837Molecular functionsequence-specific double-stranded DNA binding
GO_0005515Molecular functionprotein binding
GO_0008270Molecular functionzinc ion binding
GO_0003723Molecular functionRNA binding

IV. Literature review

[source]
Gene nameCPSF4
Protein nameCleavage and polyadenylation specific factor 4
Cleavage and polyadenylation specificity factor subunit 4 (CPSF 30 kDa subunit) (Cleavage and polyadenylation specificity factor 30 kDa subunit)
Cleavage and polyadenylation specificity factor subunit 4 (Cleavage and polyadenylation specificity factor 30 kDa subunit) (CPSF 30 kDa subunit) (NS1 effector domain-binding protein 1) (Neb-1) (No arches homolog)
SynonymsNEB1
NAR
CPSF30
DescriptionFUNCTION: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U). .

FUNCTION: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U). .

FUNCTION: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U). .

FUNCTION: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U). .

FUNCTION: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U). .

FUNCTION: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U). .

AccessionsC9K0K2
B7Z7B0
H7C419
ENST00000451876.5
O95639
ENST00000441580.5
ENST00000436336.6 [O95639-2]
ENST00000292476.10 [O95639-1]
C9JEV9
ENST00000430038.5
H7C016
F8WEL7
ENST00000440514.1
ENST00000412686.5
ENST00000452047.1