Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 11 studies | 26% ± 9% | |
| epithelial cell | 7 studies | 28% ± 11% | |
| astrocyte | 7 studies | 27% ± 9% | |
| fibroblast | 6 studies | 19% ± 5% | |
| oligodendrocyte | 6 studies | 22% ± 5% | |
| neuron | 5 studies | 30% ± 14% | |
| glutamatergic neuron | 5 studies | 38% ± 20% | |
| microglial cell | 5 studies | 21% ± 5% | |
| B cell | 5 studies | 19% ± 2% | |
| oligodendrocyte precursor cell | 5 studies | 26% ± 9% | |
| macrophage | 5 studies | 23% ± 4% | |
| pericyte | 4 studies | 21% ± 4% | |
| dendritic cell | 4 studies | 31% ± 14% | |
| goblet cell | 4 studies | 28% ± 9% | |
| myeloid cell | 3 studies | 18% ± 3% | |
| ciliated cell | 3 studies | 27% ± 5% | |
| lymphocyte | 3 studies | 22% ± 4% | |
| GABAergic neuron | 3 studies | 43% ± 13% | |
| endothelial cell of lymphatic vessel | 3 studies | 21% ± 4% | |
| transit amplifying cell | 3 studies | 26% ± 10% | |
| interneuron | 3 studies | 35% ± 19% | |
| plasmacytoid dendritic cell | 3 studies | 21% ± 4% | |
| enteroendocrine cell | 3 studies | 27% ± 9% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 5692.44 | 1445 / 1445 | 100% | 36.23 | 183 / 183 |
| intestine | 100% | 6634.67 | 966 / 966 | 100% | 36.26 | 527 / 527 |
| liver | 100% | 4283.65 | 226 / 226 | 100% | 27.89 | 406 / 406 |
| lung | 100% | 6744.13 | 578 / 578 | 100% | 32.80 | 1155 / 1155 |
| prostate | 100% | 8562.21 | 245 / 245 | 100% | 38.83 | 502 / 502 |
| thymus | 100% | 8262.31 | 653 / 653 | 100% | 38.48 | 605 / 605 |
| bladder | 100% | 6188.33 | 21 / 21 | 100% | 37.78 | 503 / 504 |
| skin | 100% | 6540.18 | 1809 / 1809 | 100% | 41.04 | 471 / 472 |
| uterus | 100% | 7489.35 | 170 / 170 | 100% | 43.86 | 458 / 459 |
| ovary | 100% | 6675.31 | 180 / 180 | 100% | 28.48 | 429 / 430 |
| pancreas | 100% | 3470.09 | 327 / 328 | 100% | 35.40 | 178 / 178 |
| stomach | 100% | 5129.54 | 359 / 359 | 100% | 34.89 | 285 / 286 |
| brain | 100% | 5540.96 | 2636 / 2642 | 100% | 32.41 | 704 / 705 |
| kidney | 100% | 6104.67 | 89 / 89 | 100% | 25.69 | 897 / 901 |
| breast | 100% | 5969.97 | 459 / 459 | 100% | 35.25 | 1113 / 1118 |
| adrenal gland | 100% | 5237.49 | 258 / 258 | 99% | 27.34 | 227 / 230 |
| adipose | 100% | 5011.10 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 31.39 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 66.97 | 29 / 29 |
| muscle | 100% | 5141.72 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 9543.20 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 41.87 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 22.71 | 1 / 1 |
| blood vessel | 100% | 5529.87 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| heart | 99% | 3533.18 | 850 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 97% | 5095.76 | 902 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0032091 | Biological process | negative regulation of protein binding |
| GO_0006397 | Biological process | mRNA processing |
| GO_0007155 | Biological process | cell adhesion |
| GO_0097165 | Cellular component | nuclear stress granule |
| GO_0005847 | Cellular component | mRNA cleavage and polyadenylation specificity factor complex |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005829 | Cellular component | cytosol |
| GO_0005856 | Cellular component | cytoskeleton |
| GO_0016604 | Cellular component | nuclear body |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005923 | Cellular component | bicellular tight junction |
| GO_0005515 | Molecular function | protein binding |
| Gene name | SYMPK |
| Protein name | Symplekin SYMPK variant protein Symplekin scaffold protein SYMPK protein |
| Synonyms | protein SPK variant |
| Description | FUNCTION: Scaffold protein that functions as a component of a multimolecular complex involved in histone mRNA 3'-end processing. Specific component of the tight junction (TJ) plaque, but might not be an exclusively junctional component. May have a house-keeping rule. Is involved in pre-mRNA polyadenylation. Enhances SSU72 phosphatase activity. . |
| Accessions | ENST00000594293.5 ENST00000599814.5 M0R180 A0A087WUE9 ENST00000599460.5 Q4LE61 Q92797 Q96B47 M0R3C7 M0R039 ENST00000598059.5 ENST00000245934.12 [Q92797-1] M0R1C2 M0QXP5 ENST00000600237.5 ENST00000602061.5 ENST00000601600.1 M0R033 ENST00000596824.1 |