PGK1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	40 studies	40% ± 15%	Explore
B cell	38 studies	38% ± 11%	Explore
macrophage	37 studies	49% ± 17%	Explore
CD8-positive, alpha-beta T cell	36 studies	49% ± 20%	Explore
natural killer cell	35 studies	46% ± 14%	Explore
fibroblast	35 studies	34% ± 15%	Explore
CD4-positive, alpha-beta T cell	32 studies	51% ± 19%	Explore
T cell	31 studies	47% ± 16%	Explore
pericyte	29 studies	35% ± 13%	Explore
classical monocyte	29 studies	54% ± 17%	Explore
conventional dendritic cell	27 studies	60% ± 17%	Explore
regulatory T cell	26 studies	51% ± 16%	Explore
dendritic cell	24 studies	53% ± 22%	Explore
smooth muscle cell	24 studies	31% ± 11%	Explore
non-classical monocyte	24 studies	71% ± 15%	Explore
monocyte	23 studies	52% ± 19%	Explore
basal cell	21 studies	44% ± 19%	Explore
epithelial cell	21 studies	45% ± 22%	Explore
memory B cell	20 studies	40% ± 14%	Explore
plasmacytoid dendritic cell	20 studies	51% ± 15%	Explore
mature NK T cell	19 studies	42% ± 15%	Explore
naive B cell	19 studies	32% ± 12%	Explore
mast cell	18 studies	37% ± 15%	Explore
gamma-delta T cell	18 studies	51% ± 19%	Explore
endothelial cell of lymphatic vessel	17 studies	36% ± 12%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	17 studies	41% ± 12%	Explore
CD16-negative, CD56-bright natural killer cell, human	16 studies	46% ± 16%	Explore
CD16-positive, CD56-dim natural killer cell, human	16 studies	45% ± 11%	Explore
connective tissue cell	16 studies	38% ± 14%	Explore
mucosal invariant T cell	15 studies	46% ± 17%	Explore
plasma cell	15 studies	45% ± 19%	Explore
myeloid cell	15 studies	52% ± 16%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	14 studies	50% ± 15%	Explore
ciliated cell	14 studies	42% ± 15%	Explore
capillary endothelial cell	13 studies	34% ± 12%	Explore
myofibroblast cell	13 studies	39% ± 11%	Explore
CD8-positive, alpha-beta memory T cell	12 studies	54% ± 17%	Explore
vein endothelial cell	12 studies	38% ± 8%	Explore
endothelial cell of vascular tree	12 studies	38% ± 13%	Explore
effector memory CD8-positive, alpha-beta T cell	11 studies	43% ± 18%	Explore
innate lymphoid cell	11 studies	48% ± 11%	Explore
CD4-positive, alpha-beta memory T cell	11 studies	51% ± 21%	Explore
neutrophil	11 studies	43% ± 16%	Explore
endothelial cell of artery	11 studies	36% ± 8%	Explore
astrocyte	11 studies	37% ± 15%	Explore
type I pneumocyte	10 studies	30% ± 12%	Explore
type II pneumocyte	10 studies	33% ± 18%	Explore
plasmablast	10 studies	60% ± 19%	Explore
secretory cell	10 studies	40% ± 20%	Explore
progenitor cell	10 studies	45% ± 19%	Explore
abnormal cell	10 studies	51% ± 24%	Explore
microglial cell	10 studies	44% ± 17%	Explore
platelet	9 studies	30% ± 9%	Explore
effector CD8-positive, alpha-beta T cell	9 studies	54% ± 23%	Explore
leukocyte	9 studies	42% ± 13%	Explore
neuron	8 studies	36% ± 18%	Explore
goblet cell	8 studies	32% ± 14%	Explore
mesothelial cell	8 studies	44% ± 14%	Explore
retinal rod cell	8 studies	40% ± 17%	Explore
alveolar macrophage	7 studies	47% ± 15%	Explore
club cell	7 studies	38% ± 14%	Explore
respiratory goblet cell	7 studies	33% ± 20%	Explore
epithelial cell of proximal tubule	7 studies	48% ± 15%	Explore
enterocyte	7 studies	30% ± 11%	Explore
hematopoietic stem cell	7 studies	61% ± 19%	Explore
T follicular helper cell	7 studies	46% ± 14%	Explore
hematopoietic precursor cell	6 studies	62% ± 21%	Explore
ionocyte	6 studies	42% ± 11%	Explore
effector CD4-positive, alpha-beta T cell	6 studies	66% ± 22%	Explore
mononuclear phagocyte	6 studies	49% ± 20%	Explore
kidney loop of Henle epithelial cell	6 studies	47% ± 9%	Explore
renal alpha-intercalated cell	6 studies	54% ± 8%	Explore
transit amplifying cell	6 studies	26% ± 7%	Explore
amacrine cell	6 studies	57% ± 20%	Explore
retinal ganglion cell	6 studies	78% ± 25%	Explore
retinal cone cell	6 studies	64% ± 18%	Explore
precursor B cell	6 studies	57% ± 12%	Explore
erythrocyte	6 studies	42% ± 18%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	56% ± 22%	Explore
CD4-positive helper T cell	5 studies	42% ± 18%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	5 studies	42% ± 15%	Explore
exhausted T cell	5 studies	58% ± 16%	Explore
glutamatergic neuron	5 studies	35% ± 21%	Explore
pro-B cell	5 studies	51% ± 16%	Explore
brush cell	5 studies	35% ± 18%	Explore
T-helper 17 cell	5 studies	63% ± 26%	Explore
retina horizontal cell	5 studies	70% ± 19%	Explore
mucus secreting cell	5 studies	20% ± 3%	Explore
Mueller cell	5 studies	46% ± 14%	Explore
intermediate monocyte	5 studies	68% ± 18%	Explore
granulocyte	5 studies	44% ± 13%	Explore
CD4-positive, alpha-beta cytotoxic T cell	4 studies	53% ± 25%	Explore
central memory CD8-positive, alpha-beta T cell	4 studies	42% ± 20%	Explore
deuterosomal cell	4 studies	21% ± 6%	Explore
squamous epithelial cell	4 studies	36% ± 21%	Explore
pancreatic A cell	4 studies	56% ± 20%	Explore
kidney distal convoluted tubule epithelial cell	4 studies	58% ± 2%	Explore
enteroendocrine cell	4 studies	42% ± 11%	Explore
retinal bipolar neuron	4 studies	48% ± 23%	Explore
OFF-bipolar cell	4 studies	70% ± 19%	Explore
ON-bipolar cell	4 studies	64% ± 20%	Explore
erythroblast	4 studies	54% ± 11%	Explore
lymphocyte	4 studies	49% ± 15%	Explore
megakaryocyte	4 studies	44% ± 12%	Explore
immature B cell	4 studies	60% ± 13%	Explore
adventitial cell	4 studies	32% ± 9%	Explore
muscle cell	4 studies	45% ± 24%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	31% ± 8%	Explore
GABAergic neuron	4 studies	38% ± 16%	Explore
megakaryocyte-erythroid progenitor cell	4 studies	63% ± 30%	Explore
hepatocyte	4 studies	45% ± 23%	Explore
group 3 innate lymphoid cell	4 studies	66% ± 10%	Explore
interneuron	4 studies	35% ± 19%	Explore
duct epithelial cell	3 studies	34% ± 9%	Explore
precursor cell	3 studies	61% ± 4%	Explore
type B pancreatic cell	3 studies	64% ± 15%	Explore
monocyte-derived dendritic cell	3 studies	56% ± 22%	Explore
glomerular endothelial cell	3 studies	30% ± 9%	Explore
podocyte	3 studies	51% ± 12%	Explore
intestinal crypt stem cell	3 studies	32% ± 9%	Explore
neural crest cell	3 studies	39% ± 8%	Explore
GABAergic amacrine cell	3 studies	65% ± 7%	Explore
glycinergic amacrine cell	3 studies	59% ± 13%	Explore
thymocyte	3 studies	46% ± 28%	Explore
extravillous trophoblast	3 studies	79% ± 6%	Explore
placental villous trophoblast	3 studies	62% ± 6%	Explore
neuroendocrine cell	3 studies	48% ± 18%	Explore
retinal pigment epithelial cell	3 studies	42% ± 20%	Explore
serous secreting cell	3 studies	30% ± 10%	Explore
tissue-resident macrophage	3 studies	42% ± 16%	Explore
intraepithelial lymphocyte	3 studies	55% ± 16%	Explore
rod bipolar cell	3 studies	63% ± 6%	Explore
cardiac muscle cell	3 studies	30% ± 10%	Explore
germinal center B cell	3 studies	47% ± 14%	Explore
myoepithelial cell	3 studies	36% ± 5%	Explore
inflammatory macrophage	3 studies	38% ± 8%	Explore
pancreatic ductal cell	3 studies	71% ± 18%	Explore
oligodendrocyte precursor cell	3 studies	31% ± 7%	Explore
keratinocyte	3 studies	30% ± 8%	Explore
T-helper 1 cell	3 studies	74% ± 14%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	49% ± 21%	Explore
double negative thymocyte	3 studies	67% ± 11%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	20 studies	49% ± 12%	Explore
lung	19 studies	43% ± 14%	Explore
intestine	13 studies	30% ± 11%	Explore
eye	11 studies	44% ± 17%	Explore
kidney	9 studies	47% ± 12%	Explore
brain	9 studies	33% ± 15%	Explore
bone marrow	6 studies	38% ± 14%	Explore
liver	6 studies	42% ± 15%	Explore
lymph node	6 studies	53% ± 13%	Explore
pancreas	5 studies	47% ± 23%	Explore
uterus	5 studies	44% ± 21%	Explore
placenta	4 studies	57% ± 17%	Explore
prostate	4 studies	27% ± 6%	Explore
breast	4 studies	34% ± 5%	Explore
ovary	3 studies	20% ± 5%	Explore
heart	3 studies	25% ± 7%	Explore
adipose	3 studies	29% ± 9%	Explore
adrenal gland	3 studies	47% ± 12%	Explore
esophagus	3 studies	44% ± 20%	Explore
skin	3 studies	24% ± 7%	Explore
thymus	3 studies	62% ± 27%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	21454.96	1445 / 1445	100%	257.25	183 / 183
lung	100%	17842.81	576 / 578	100%	459.25	1151 / 1155
ovary	100%	10136.95	180 / 180	99%	287.59	427 / 430
stomach	100%	11013.95	358 / 359	99%	301.37	283 / 286
intestine	100%	13841.34	966 / 966	99%	374.51	520 / 527
breast	100%	14618.12	459 / 459	99%	309.22	1103 / 1118
uterus	100%	10386.85	170 / 170	98%	372.30	450 / 459
kidney	100%	21152.22	89 / 89	98%	500.46	883 / 901
skin	100%	25408.22	1808 / 1809	98%	410.13	462 / 472
bladder	100%	14871.43	21 / 21	96%	360.48	486 / 504
brain	97%	13640.58	2568 / 2642	99%	258.64	699 / 705
thymus	100%	13093.08	651 / 653	94%	162.31	571 / 605
prostate	100%	11145.08	244 / 245	94%	161.01	473 / 502
adrenal gland	100%	21499.13	258 / 258	89%	276.91	205 / 230
pancreas	84%	4990.14	274 / 328	97%	260.06	173 / 178
liver	92%	10240.22	207 / 226	88%	158.16	356 / 406
adipose	100%	17369.73	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	323.92	29 / 29
muscle	100%	26139.54	803 / 803	0%	0	0 / 0
spleen	100%	17817.57	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	417.49	45 / 45
blood vessel	100%	16596.16	1333 / 1335	0%	0	0 / 0
peripheral blood	100%	54825.49	926 / 929	0%	0	0 / 0
heart	96%	21110.65	824 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	88%	167.03	70 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

III. Associated gene sets

GO_0016310	Biological process	phosphorylation
GO_0061621	Biological process	canonical glycolysis
GO_0006094	Biological process	gluconeogenesis
GO_0006096	Biological process	glycolytic process
GO_0031639	Biological process	plasminogen activation
GO_0030855	Biological process	epithelial cell differentiation
GO_0071456	Biological process	cellular response to hypoxia
GO_0016525	Biological process	negative regulation of angiogenesis
GO_0045121	Cellular component	membrane raft
GO_0005615	Cellular component	extracellular space
GO_0070062	Cellular component	extracellular exosome
GO_0005829	Cellular component	cytosol
GO_0016020	Cellular component	membrane
GO_0043531	Molecular function	ADP binding
GO_0004618	Molecular function	phosphoglycerate kinase activity
GO_0047134	Molecular function	protein-disulfide reductase (NAD(P)H) activity
GO_0005515	Molecular function	protein binding
GO_0005524	Molecular function	ATP binding

Gene name	PGK1
Protein name	Phosphoglycerate kinase 1 (EC 2.7.2.3) (Cell migration-inducing gene 10 protein) (Primer recognition protein 2) (PRP 2)
Synonyms	PGKA MIG10 OK/SW-cl.110
Description	FUNCTION: Catalyzes one of the two ATP producing reactions in the glycolytic pathway via the reversible conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate . In addition to its role as a glycolytic enzyme, it seems that PGK-1 acts as a polymerase alpha cofactor protein (primer recognition protein) . May play a role in sperm motility . .
Accessions	P00558 ENST00000644362.1 [P00558-2] ENST00000373316.5 [P00558-1]

PGK1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review