Name | Number of supported studies | Average coverage | |
---|---|---|---|
lung | 17 studies | 40% ± 14% | |
peripheral blood | 15 studies | 34% ± 10% | |
intestine | 10 studies | 31% ± 13% | |
kidney | 8 studies | 36% ± 9% | |
liver | 7 studies | 34% ± 20% | |
eye | 6 studies | 26% ± 4% | |
brain | 6 studies | 33% ± 9% | |
lymph node | 5 studies | 41% ± 10% | |
pancreas | 4 studies | 56% ± 18% | |
uterus | 4 studies | 41% ± 18% | |
breast | 4 studies | 35% ± 4% | |
placenta | 3 studies | 58% ± 12% | |
bone marrow | 3 studies | 33% ± 13% | |
prostate | 3 studies | 43% ± 10% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 4814.06 | 1445 / 1445 | 69% | 1.78 | 127 / 183 |
lung | 99% | 3552.54 | 575 / 578 | 42% | 1.26 | 480 / 1155 |
breast | 100% | 3777.98 | 459 / 459 | 38% | 0.91 | 421 / 1118 |
stomach | 100% | 3942.72 | 359 / 359 | 37% | 1.04 | 105 / 286 |
bladder | 100% | 3432.43 | 21 / 21 | 37% | 0.96 | 184 / 504 |
uterus | 100% | 2532.18 | 170 / 170 | 32% | 0.67 | 145 / 459 |
intestine | 100% | 4450.15 | 966 / 966 | 31% | 0.77 | 166 / 527 |
kidney | 100% | 5668.00 | 89 / 89 | 31% | 0.66 | 282 / 901 |
pancreas | 100% | 2297.73 | 328 / 328 | 28% | 0.64 | 50 / 178 |
prostate | 100% | 3436.37 | 245 / 245 | 20% | 0.45 | 99 / 502 |
ovary | 100% | 1969.93 | 180 / 180 | 17% | 0.27 | 72 / 430 |
brain | 99% | 3598.72 | 2628 / 2642 | 12% | 0.21 | 88 / 705 |
liver | 100% | 7919.86 | 226 / 226 | 11% | 0.18 | 43 / 406 |
thymus | 100% | 3037.09 | 651 / 653 | 9% | 0.12 | 55 / 605 |
skin | 100% | 3826.79 | 1808 / 1809 | 7% | 0.12 | 35 / 472 |
adrenal gland | 100% | 6276.95 | 258 / 258 | 3% | 0.04 | 6 / 230 |
adipose | 100% | 3696.78 | 1204 / 1204 | 0% | 0 | 0 / 0 |
muscle | 100% | 11423.76 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 3286.32 | 241 / 241 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 3343.55 | 1331 / 1335 | 0% | 0 | 0 / 0 |
heart | 99% | 8218.62 | 849 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 87% | 2948.41 | 806 / 929 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 34% | 0.51 | 10 / 29 |
tonsil | 0% | 0 | 0 / 0 | 22% | 0.27 | 10 / 45 |
eye | 0% | 0 | 0 / 0 | 3% | 0.03 | 2 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0048738 | Biological process | cardiac muscle tissue development |
GO_0009060 | Biological process | aerobic respiration |
GO_0006120 | Biological process | mitochondrial electron transport, NADH to ubiquinone |
GO_0007399 | Biological process | nervous system development |
GO_0042776 | Biological process | proton motive force-driven mitochondrial ATP synthesis |
GO_0055085 | Biological process | transmembrane transport |
GO_0045271 | Cellular component | respiratory chain complex I |
GO_0005743 | Cellular component | mitochondrial inner membrane |
GO_0005739 | Cellular component | mitochondrion |
GO_0051537 | Molecular function | 2 iron, 2 sulfur cluster binding |
GO_0008137 | Molecular function | NADH dehydrogenase (ubiquinone) activity |
GO_0003954 | Molecular function | NADH dehydrogenase activity |
GO_0005515 | Molecular function | protein binding |
GO_0046872 | Molecular function | metal ion binding |
GO_0009055 | Molecular function | electron transfer activity |
Gene name | NDUFV2 |
Protein name | NADH:ubiquinone oxidoreductase core subunit V2 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (NDUFV2) (EC 7.1.1.2) (NADH-ubiquinone oxidoreductase 24 kDa subunit) NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (NADH-ubiquinone oxidoreductase 24 kDa subunit) |
Synonyms | hCG_1994226 |
Description | FUNCTION: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor (Probable). Parts of the peripheral arm of the enzyme, where the electrons from NADH are accepted by flavin mononucleotide (FMN) and then passed along a chain of iron-sulfur clusters by electron tunnelling to the final acceptor ubiquinone (Probable). Contains one iron-sulfur cluster (Probable). . |
Accessions | Q6IB76 Q6IPW4 ENST00000318388.11 J3QS34 ENST00000577703.1 P19404 ENST00000400033.1 E7EPT4 J3KRB4 ENST00000497577.2 Q9UEH5 |