MDH2 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
natural killer cell	31 studies	33% ± 12%	Explore
B cell	29 studies	29% ± 10%	Explore
CD8-positive, alpha-beta T cell	28 studies	37% ± 17%	Explore
fibroblast	28 studies	29% ± 13%	Explore
CD4-positive, alpha-beta T cell	27 studies	36% ± 18%	Explore
conventional dendritic cell	25 studies	41% ± 17%	Explore
smooth muscle cell	23 studies	32% ± 14%	Explore
macrophage	23 studies	30% ± 10%	Explore
regulatory T cell	23 studies	39% ± 15%	Explore
T cell	22 studies	33% ± 11%	Explore
non-classical monocyte	21 studies	40% ± 15%	Explore
classical monocyte	21 studies	33% ± 14%	Explore
pericyte	21 studies	31% ± 11%	Explore
endothelial cell	20 studies	31% ± 13%	Explore
epithelial cell	19 studies	43% ± 20%	Explore
basal cell	18 studies	43% ± 18%	Explore
monocyte	17 studies	29% ± 10%	Explore
memory B cell	17 studies	30% ± 10%	Explore
plasmacytoid dendritic cell	17 studies	39% ± 14%	Explore
ciliated cell	16 studies	40% ± 17%	Explore
naive B cell	16 studies	26% ± 7%	Explore
gamma-delta T cell	15 studies	35% ± 15%	Explore
endothelial cell of lymphatic vessel	14 studies	32% ± 10%	Explore
CD16-positive, CD56-dim natural killer cell, human	14 studies	35% ± 12%	Explore
mature NK T cell	14 studies	33% ± 9%	Explore
connective tissue cell	14 studies	34% ± 13%	Explore
mast cell	13 studies	25% ± 15%	Explore
CD16-negative, CD56-bright natural killer cell, human	13 studies	35% ± 11%	Explore
plasma cell	13 studies	43% ± 15%	Explore
dendritic cell	12 studies	50% ± 23%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	12 studies	31% ± 9%	Explore
myofibroblast cell	12 studies	36% ± 12%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	11 studies	38% ± 10%	Explore
plasmablast	10 studies	53% ± 22%	Explore
CD4-positive, alpha-beta memory T cell	10 studies	36% ± 16%	Explore
secretory cell	10 studies	38% ± 18%	Explore
abnormal cell	10 studies	41% ± 17%	Explore
mucosal invariant T cell	10 studies	32% ± 7%	Explore
CD8-positive, alpha-beta memory T cell	9 studies	39% ± 16%	Explore
progenitor cell	9 studies	51% ± 12%	Explore
capillary endothelial cell	9 studies	23% ± 11%	Explore
endothelial cell of artery	9 studies	21% ± 5%	Explore
goblet cell	9 studies	37% ± 13%	Explore
myeloid cell	9 studies	28% ± 12%	Explore
endothelial cell of vascular tree	8 studies	23% ± 5%	Explore
type I pneumocyte	7 studies	28% ± 13%	Explore
club cell	7 studies	40% ± 8%	Explore
effector memory CD8-positive, alpha-beta T cell	7 studies	37% ± 11%	Explore
vein endothelial cell	7 studies	25% ± 9%	Explore
T follicular helper cell	7 studies	28% ± 7%	Explore
respiratory goblet cell	6 studies	38% ± 23%	Explore
effector CD8-positive, alpha-beta T cell	6 studies	48% ± 20%	Explore
epithelial cell of proximal tubule	6 studies	41% ± 10%	Explore
renal alpha-intercalated cell	6 studies	54% ± 11%	Explore
transit amplifying cell	6 studies	38% ± 19%	Explore
precursor B cell	6 studies	36% ± 11%	Explore
innate lymphoid cell	6 studies	25% ± 10%	Explore
alveolar macrophage	5 studies	24% ± 7%	Explore
hematopoietic precursor cell	5 studies	49% ± 25%	Explore
exhausted T cell	5 studies	48% ± 11%	Explore
ionocyte	5 studies	38% ± 11%	Explore
mononuclear phagocyte	5 studies	34% ± 18%	Explore
kidney loop of Henle epithelial cell	5 studies	40% ± 11%	Explore
neuron	5 studies	46% ± 20%	Explore
enterocyte	5 studies	43% ± 9%	Explore
enteroendocrine cell	5 studies	44% ± 17%	Explore
intestinal crypt stem cell	5 studies	45% ± 15%	Explore
mesothelial cell	5 studies	50% ± 17%	Explore
hematopoietic stem cell	5 studies	51% ± 8%	Explore
brush cell	5 studies	29% ± 17%	Explore
type II pneumocyte	5 studies	39% ± 14%	Explore
erythrocyte	5 studies	40% ± 25%	Explore
deuterosomal cell	4 studies	32% ± 9%	Explore
pancreatic A cell	4 studies	64% ± 15%	Explore
type B pancreatic cell	4 studies	56% ± 21%	Explore
leukocyte	4 studies	35% ± 10%	Explore
kidney distal convoluted tubule epithelial cell	4 studies	52% ± 7%	Explore
retinal ganglion cell	4 studies	53% ± 26%	Explore
erythroblast	4 studies	41% ± 17%	Explore
pro-B cell	4 studies	30% ± 8%	Explore
immature B cell	4 studies	44% ± 12%	Explore
adventitial cell	4 studies	25% ± 7%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	62% ± 11%	Explore
intermediate monocyte	4 studies	46% ± 19%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	37% ± 11%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	49% ± 17%	Explore
granulocyte	4 studies	28% ± 7%	Explore
hepatocyte	4 studies	39% ± 21%	Explore
T-helper 17 cell	4 studies	36% ± 27%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	32% ± 9%	Explore
duct epithelial cell	3 studies	40% ± 11%	Explore
precursor cell	3 studies	62% ± 6%	Explore
squamous epithelial cell	3 studies	37% ± 27%	Explore
neural crest cell	3 studies	41% ± 3%	Explore
retinal bipolar neuron	3 studies	34% ± 15%	Explore
placental villous trophoblast	3 studies	63% ± 17%	Explore
common myeloid progenitor	3 studies	48% ± 20%	Explore
lymphocyte	3 studies	40% ± 13%	Explore
megakaryocyte	3 studies	27% ± 9%	Explore
neuroendocrine cell	3 studies	43% ± 16%	Explore
amacrine cell	3 studies	38% ± 15%	Explore
retina horizontal cell	3 studies	34% ± 19%	Explore
retinal cone cell	3 studies	55% ± 17%	Explore
retinal rod cell	3 studies	30% ± 12%	Explore
serous secreting cell	3 studies	45% ± 4%	Explore
intraepithelial lymphocyte	3 studies	35% ± 13%	Explore
germinal center B cell	3 studies	40% ± 8%	Explore
myoepithelial cell	3 studies	31% ± 9%	Explore
GABAergic neuron	3 studies	22% ± 5%	Explore
acinar cell	3 studies	34% ± 13%	Explore
pancreatic ductal cell	3 studies	55% ± 7%	Explore
granulocyte monocyte progenitor cell	3 studies	50% ± 18%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	59% ± 23%	Explore
group 3 innate lymphoid cell	3 studies	40% ± 14%	Explore
keratinocyte	3 studies	32% ± 5%	Explore
T-helper 1 cell	3 studies	48% ± 22%	Explore
double negative thymocyte	3 studies	55% ± 16%	Explore
progenitor cell of mammary luminal epithelium	3 studies	40% ± 11%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
lung	16 studies	36% ± 16%	Explore
peripheral blood	16 studies	37% ± 10%	Explore
intestine	10 studies	32% ± 15%	Explore
kidney	7 studies	36% ± 4%	Explore
liver	7 studies	27% ± 16%	Explore
eye	6 studies	26% ± 13%	Explore
lymph node	5 studies	37% ± 12%	Explore
brain	5 studies	25% ± 6%	Explore
pancreas	4 studies	56% ± 19%	Explore
uterus	4 studies	37% ± 16%	Explore
breast	4 studies	28% ± 7%	Explore
placenta	3 studies	39% ± 19%	Explore
bone marrow	3 studies	26% ± 6%	Explore
adrenal gland	3 studies	28% ± 9%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	10510.82	1445 / 1445	100%	219.06	183 / 183
ovary	100%	6324.87	180 / 180	100%	283.89	430 / 430
pancreas	100%	6369.34	328 / 328	100%	171.76	178 / 178
skin	100%	11020.37	1809 / 1809	100%	311.11	471 / 472
uterus	100%	6615.89	170 / 170	100%	211.45	458 / 459
stomach	100%	8071.56	359 / 359	100%	292.13	285 / 286
intestine	100%	10589.86	966 / 966	100%	329.95	525 / 527
prostate	100%	6923.55	245 / 245	99%	251.73	499 / 502
thymus	100%	6844.09	651 / 653	100%	156.12	603 / 605
liver	100%	11824.23	225 / 226	100%	226.13	405 / 406
breast	100%	7722.01	459 / 459	99%	215.81	1107 / 1118
kidney	100%	10546.42	89 / 89	99%	177.13	891 / 901
lung	99%	6606.95	573 / 578	99%	218.52	1149 / 1155
bladder	100%	8634.52	21 / 21	99%	246.14	497 / 504
adrenal gland	100%	16111.86	258 / 258	98%	187.22	225 / 230
brain	97%	6510.20	2554 / 2642	100%	202.40	705 / 705
eye	0%	0	0 / 0	100%	280.08	80 / 80
lymph node	0%	0	0 / 0	100%	275.20	29 / 29
muscle	100%	36503.38	803 / 803	0%	0	0 / 0
spleen	100%	7322.93	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	216.33	45 / 45
ureter	0%	0	0 / 0	100%	88.45	1 / 1
adipose	100%	7598.31	1203 / 1204	0%	0	0 / 0
blood vessel	100%	7051.50	1330 / 1335	0%	0	0 / 0
heart	98%	21242.28	846 / 861	0%	0	0 / 0
peripheral blood	85%	6497.70	792 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0