ILF2 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
B cell	30 studies	27% ± 9%	Explore
natural killer cell	28 studies	30% ± 11%	Explore
endothelial cell	26 studies	32% ± 14%	Explore
fibroblast	25 studies	33% ± 13%	Explore
CD4-positive, alpha-beta T cell	24 studies	33% ± 16%	Explore
T cell	23 studies	30% ± 13%	Explore
CD8-positive, alpha-beta T cell	23 studies	33% ± 14%	Explore
conventional dendritic cell	22 studies	28% ± 14%	Explore
regulatory T cell	21 studies	30% ± 11%	Explore
basal cell	19 studies	33% ± 16%	Explore
smooth muscle cell	19 studies	29% ± 11%	Explore
memory B cell	18 studies	26% ± 11%	Explore
pericyte	18 studies	31% ± 13%	Explore
naive B cell	16 studies	26% ± 8%	Explore
epithelial cell	16 studies	40% ± 22%	Explore
plasmacytoid dendritic cell	15 studies	37% ± 13%	Explore
connective tissue cell	15 studies	37% ± 20%	Explore
CD16-positive, CD56-dim natural killer cell, human	14 studies	27% ± 8%	Explore
macrophage	14 studies	24% ± 9%	Explore
gamma-delta T cell	14 studies	31% ± 17%	Explore
mast cell	13 studies	28% ± 14%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	13 studies	25% ± 7%	Explore
mature NK T cell	13 studies	27% ± 8%	Explore
endothelial cell of lymphatic vessel	12 studies	30% ± 12%	Explore
plasma cell	12 studies	38% ± 15%	Explore
classical monocyte	12 studies	25% ± 10%	Explore
CD16-negative, CD56-bright natural killer cell, human	12 studies	31% ± 7%	Explore
secretory cell	11 studies	26% ± 11%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	11 studies	28% ± 7%	Explore
capillary endothelial cell	11 studies	28% ± 14%	Explore
vein endothelial cell	11 studies	30% ± 13%	Explore
endothelial cell of vascular tree	11 studies	32% ± 11%	Explore
CD8-positive, alpha-beta memory T cell	10 studies	28% ± 9%	Explore
myofibroblast cell	10 studies	40% ± 13%	Explore
abnormal cell	10 studies	34% ± 13%	Explore
endothelial cell of artery	10 studies	26% ± 7%	Explore
plasmablast	9 studies	48% ± 22%	Explore
non-classical monocyte	9 studies	28% ± 11%	Explore
monocyte	9 studies	24% ± 7%	Explore
mucosal invariant T cell	9 studies	31% ± 6%	Explore
ciliated cell	9 studies	34% ± 12%	Explore
effector CD8-positive, alpha-beta T cell	8 studies	31% ± 16%	Explore
CD4-positive, alpha-beta memory T cell	7 studies	30% ± 7%	Explore
effector memory CD8-positive, alpha-beta T cell	7 studies	30% ± 10%	Explore
epithelial cell of proximal tubule	7 studies	24% ± 7%	Explore
progenitor cell	7 studies	49% ± 13%	Explore
goblet cell	7 studies	24% ± 9%	Explore
dendritic cell	7 studies	41% ± 21%	Explore
precursor B cell	7 studies	47% ± 12%	Explore
innate lymphoid cell	7 studies	28% ± 5%	Explore
neuron	7 studies	43% ± 22%	Explore
mesothelial cell	6 studies	49% ± 16%	Explore
hematopoietic stem cell	6 studies	49% ± 15%	Explore
myeloid cell	6 studies	26% ± 11%	Explore
erythrocyte	6 studies	37% ± 26%	Explore
T follicular helper cell	6 studies	25% ± 3%	Explore
leukocyte	5 studies	29% ± 10%	Explore
kidney loop of Henle epithelial cell	5 studies	20% ± 5%	Explore
enteroendocrine cell	5 studies	35% ± 12%	Explore
transit amplifying cell	5 studies	24% ± 7%	Explore
erythroblast	5 studies	47% ± 20%	Explore
pro-B cell	5 studies	48% ± 8%	Explore
effector CD4-positive, alpha-beta T cell	5 studies	31% ± 12%	Explore
effector memory CD4-positive, alpha-beta T cell	5 studies	34% ± 9%	Explore
glutamatergic neuron	5 studies	23% ± 5%	Explore
hematopoietic precursor cell	4 studies	61% ± 22%	Explore
deuterosomal cell	4 studies	28% ± 3%	Explore
pancreatic A cell	4 studies	36% ± 12%	Explore
mononuclear phagocyte	4 studies	26% ± 12%	Explore
exhausted T cell	4 studies	31% ± 4%	Explore
kidney distal convoluted tubule epithelial cell	4 studies	45% ± 22%	Explore
intestinal crypt stem cell	4 studies	26% ± 4%	Explore
club cell	4 studies	38% ± 8%	Explore
immature B cell	4 studies	45% ± 16%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	41% ± 12%	Explore
granulocyte	4 studies	29% ± 10%	Explore
GABAergic neuron	4 studies	19% ± 1%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	24% ± 7%	Explore
precursor cell	3 studies	64% ± 18%	Explore
respiratory goblet cell	3 studies	34% ± 24%	Explore
type B pancreatic cell	3 studies	46% ± 4%	Explore
neural crest cell	3 studies	60% ± 17%	Explore
placental villous trophoblast	3 studies	31% ± 17%	Explore
common myeloid progenitor	3 studies	42% ± 26%	Explore
lymphocyte	3 studies	38% ± 8%	Explore
brush cell	3 studies	38% ± 16%	Explore
neuroendocrine cell	3 studies	36% ± 10%	Explore
type I pneumocyte	3 studies	36% ± 7%	Explore
type II pneumocyte	3 studies	40% ± 8%	Explore
serous secreting cell	3 studies	21% ± 2%	Explore
muscle cell	3 studies	27% ± 12%	Explore
germinal center B cell	3 studies	32% ± 9%	Explore
myoepithelial cell	3 studies	41% ± 12%	Explore
pancreatic ductal cell	3 studies	50% ± 16%	Explore
oligodendrocyte precursor cell	3 studies	39% ± 17%	Explore
granulocyte monocyte progenitor cell	3 studies	41% ± 32%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	51% ± 30%	Explore
group 3 innate lymphoid cell	3 studies	45% ± 16%	Explore
keratinocyte	3 studies	22% ± 3%	Explore
interneuron	3 studies	17% ± 2%	Explore
T-helper 1 cell	3 studies	33% ± 9%	Explore
double negative thymocyte	3 studies	51% ± 24%	Explore
CD4-positive, alpha-beta cytotoxic T cell	3 studies	29% ± 6%	Explore
progenitor cell of mammary luminal epithelium	3 studies	40% ± 13%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	15 studies	29% ± 10%	Explore
lung	11 studies	33% ± 12%	Explore
kidney	8 studies	28% ± 10%	Explore
intestine	8 studies	29% ± 14%	Explore
brain	6 studies	20% ± 6%	Explore
lymph node	6 studies	28% ± 11%	Explore
bone marrow	5 studies	22% ± 2%	Explore
uterus	5 studies	30% ± 13%	Explore
liver	5 studies	30% ± 21%	Explore
eye	4 studies	26% ± 8%	Explore
prostate	4 studies	25% ± 6%	Explore
breast	4 studies	33% ± 10%	Explore
pancreas	3 studies	45% ± 4%	Explore
placenta	3 studies	25% ± 13%	Explore
adrenal gland	3 studies	26% ± 7%	Explore
skin	3 studies	20% ± 1%	Explore
thymus	3 studies	58% ± 28%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
lung	100%	6450.84	578 / 578	100%	365.07	1155 / 1155
ovary	100%	5933.23	180 / 180	100%	380.13	430 / 430
stomach	100%	4914.89	359 / 359	100%	262.06	286 / 286
esophagus	100%	5134.18	1444 / 1445	100%	263.78	183 / 183
breast	100%	6813.31	459 / 459	100%	449.66	1117 / 1118
uterus	100%	5773.10	170 / 170	100%	398.54	458 / 459
intestine	100%	5141.94	966 / 966	100%	288.16	525 / 527
pancreas	100%	3876.68	328 / 328	99%	223.16	177 / 178
bladder	100%	4995.62	21 / 21	99%	344.15	501 / 504
skin	100%	7872.14	1809 / 1809	99%	308.36	469 / 472
thymus	100%	6544.58	653 / 653	99%	271.80	601 / 605
brain	99%	3722.49	2628 / 2642	100%	300.80	704 / 705
prostate	100%	5015.42	245 / 245	99%	240.11	498 / 502
kidney	100%	6748.80	89 / 89	95%	159.45	858 / 901
liver	99%	2736.12	223 / 226	97%	177.69	392 / 406
adrenal gland	100%	6769.94	258 / 258	93%	164.71	213 / 230
adipose	100%	6188.77	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	403.17	29 / 29
muscle	100%	5168.97	803 / 803	0%	0	0 / 0
spleen	100%	6674.18	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	325.28	45 / 45
ureter	0%	0	0 / 0	100%	162.53	1 / 1
blood vessel	100%	4999.26	1334 / 1335	0%	0	0 / 0
heart	98%	3774.35	844 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	96%	152.94	77 / 80
peripheral blood	95%	5082.41	884 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0045893	Biological process	positive regulation of DNA-templated transcription
GO_0005730	Cellular component	nucleolus
GO_1904724	Cellular component	tertiary granule lumen
GO_1904813	Cellular component	ficolin-1-rich granule lumen
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_1990904	Cellular component	ribonucleoprotein complex
GO_0005576	Cellular component	extracellular region
GO_0016020	Cellular component	membrane
GO_0035580	Cellular component	specific granule lumen
GO_0005634	Cellular component	nucleus
GO_0003677	Molecular function	DNA binding
GO_0005515	Molecular function	protein binding
GO_0003725	Molecular function	double-stranded RNA binding
GO_0003723	Molecular function	RNA binding

IV. Literature review

[source]

Gene name	ILF2
Protein name	Interleukin enhancer-binding factor 2 (Nuclear factor of activated T-cells 45 kDa) Interleukin enhancer binding factor 2 Interleukin enhancer binding factor 2 (cDNA FLJ51660, highly similar to Interleukin enhancer-binding factor 2)
Synonyms	NF45 PRO3063
Description	FUNCTION: Chromatin-interacting protein that forms a stable heterodimer with interleukin enhancer-binding factor 3/ILF3 and plays a role in several biological processes including transcription, innate immunity or cell growth . Essential for the efficient reshuttling of ILF3 (isoform 1 and isoform 2) into the nucleus. Together with ILF3, forms an RNA-binding complex that is required for mitotic progression and cytokinesis by regulating the expression of a cluster of mitotic genes. Mechanistically, competes with STAU1/STAU2-mediated mRNA decay . Also plays a role in the inhibition of various viruses including Japanese encephalitis virus or enterovirus 71. .; FUNCTION: (Microbial infection) Plays a positive role in HIV-1 virus production by binding to and thereby stabilizing HIV-1 RNA, together with ILF3. .
Accessions	ENST00000368681.1 B4DY09 Q12905 X6R6Z1 ENST00000368684.8 ENST00000361891.9 ENST00000615950.4 A0A0A0MRL0

ILF2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review