HP1BP3 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	44 studies	35% ± 14%	Explore
fibroblast	43 studies	33% ± 12%	Explore
B cell	36 studies	29% ± 9%	Explore
natural killer cell	35 studies	34% ± 12%	Explore
macrophage	33 studies	29% ± 11%	Explore
pericyte	33 studies	32% ± 12%	Explore
CD8-positive, alpha-beta T cell	33 studies	31% ± 11%	Explore
T cell	32 studies	29% ± 10%	Explore
CD4-positive, alpha-beta T cell	32 studies	32% ± 11%	Explore
smooth muscle cell	29 studies	32% ± 10%	Explore
regulatory T cell	24 studies	33% ± 8%	Explore
conventional dendritic cell	21 studies	28% ± 14%	Explore
non-classical monocyte	21 studies	31% ± 14%	Explore
memory B cell	20 studies	30% ± 7%	Explore
naive B cell	20 studies	28% ± 8%	Explore
classical monocyte	20 studies	28% ± 11%	Explore
endothelial cell of lymphatic vessel	19 studies	35% ± 13%	Explore
mast cell	18 studies	28% ± 10%	Explore
monocyte	18 studies	26% ± 9%	Explore
gamma-delta T cell	18 studies	36% ± 14%	Explore
mature NK T cell	18 studies	31% ± 8%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	18 studies	33% ± 9%	Explore
epithelial cell	18 studies	35% ± 20%	Explore
astrocyte	17 studies	37% ± 16%	Explore
CD16-negative, CD56-bright natural killer cell, human	16 studies	33% ± 10%	Explore
basal cell	16 studies	35% ± 14%	Explore
connective tissue cell	16 studies	34% ± 12%	Explore
oligodendrocyte	16 studies	42% ± 19%	Explore
mucosal invariant T cell	15 studies	32% ± 9%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	15 studies	35% ± 8%	Explore
plasmacytoid dendritic cell	15 studies	34% ± 10%	Explore
CD16-positive, CD56-dim natural killer cell, human	15 studies	37% ± 10%	Explore
oligodendrocyte precursor cell	15 studies	40% ± 19%	Explore
dendritic cell	14 studies	35% ± 20%	Explore
capillary endothelial cell	14 studies	28% ± 9%	Explore
myofibroblast cell	14 studies	37% ± 10%	Explore
effector memory CD8-positive, alpha-beta T cell	13 studies	35% ± 11%	Explore
CD8-positive, alpha-beta memory T cell	13 studies	37% ± 10%	Explore
glutamatergic neuron	13 studies	45% ± 25%	Explore
vein endothelial cell	13 studies	28% ± 12%	Explore
type I pneumocyte	12 studies	30% ± 12%	Explore
CD4-positive, alpha-beta memory T cell	12 studies	33% ± 10%	Explore
microglial cell	12 studies	38% ± 15%	Explore
GABAergic neuron	11 studies	40% ± 23%	Explore
neuron	10 studies	42% ± 18%	Explore
endothelial cell of artery	10 studies	28% ± 6%	Explore
mesothelial cell	10 studies	32% ± 13%	Explore
endothelial cell of vascular tree	10 studies	28% ± 11%	Explore
myeloid cell	10 studies	28% ± 12%	Explore
type II pneumocyte	9 studies	27% ± 12%	Explore
plasma cell	9 studies	31% ± 10%	Explore
abnormal cell	9 studies	35% ± 15%	Explore
adipocyte	9 studies	36% ± 14%	Explore
plasmablast	8 studies	38% ± 20%	Explore
club cell	8 studies	27% ± 7%	Explore
effector CD8-positive, alpha-beta T cell	8 studies	33% ± 10%	Explore
amacrine cell	8 studies	32% ± 15%	Explore
ciliated cell	8 studies	29% ± 17%	Explore
alveolar macrophage	7 studies	28% ± 8%	Explore
secretory cell	7 studies	35% ± 12%	Explore
leukocyte	7 studies	37% ± 10%	Explore
goblet cell	7 studies	30% ± 15%	Explore
interneuron	7 studies	50% ± 19%	Explore
precursor B cell	7 studies	38% ± 18%	Explore
retinal rod cell	7 studies	24% ± 5%	Explore
T follicular helper cell	7 studies	35% ± 9%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	6 studies	28% ± 6%	Explore
hematopoietic precursor cell	6 studies	41% ± 13%	Explore
ionocyte	6 studies	36% ± 14%	Explore
mononuclear phagocyte	6 studies	24% ± 11%	Explore
kidney loop of Henle epithelial cell	6 studies	24% ± 4%	Explore
transit amplifying cell	6 studies	39% ± 21%	Explore
lymphocyte	6 studies	41% ± 10%	Explore
retina horizontal cell	6 studies	38% ± 13%	Explore
Mueller cell	6 studies	30% ± 9%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	39% ± 7%	Explore
innate lymphoid cell	6 studies	32% ± 8%	Explore
exhausted T cell	5 studies	39% ± 9%	Explore
respiratory goblet cell	5 studies	24% ± 7%	Explore
progenitor cell	5 studies	38% ± 6%	Explore
kidney distal convoluted tubule epithelial cell	5 studies	29% ± 5%	Explore
renal alpha-intercalated cell	5 studies	33% ± 6%	Explore
retinal bipolar neuron	5 studies	32% ± 14%	Explore
glial cell	5 studies	33% ± 15%	Explore
hematopoietic stem cell	5 studies	37% ± 10%	Explore
pro-B cell	5 studies	40% ± 7%	Explore
brush cell	5 studies	31% ± 10%	Explore
CD4-positive helper T cell	4 studies	32% ± 9%	Explore
central memory CD8-positive, alpha-beta T cell	4 studies	31% ± 6%	Explore
precursor cell	4 studies	39% ± 9%	Explore
squamous epithelial cell	4 studies	32% ± 24%	Explore
pancreatic A cell	4 studies	35% ± 20%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	38% ± 2%	Explore
granule cell	4 studies	25% ± 7%	Explore
retinal ganglion cell	4 studies	34% ± 15%	Explore
immature B cell	4 studies	31% ± 9%	Explore
retinal cone cell	4 studies	41% ± 11%	Explore
cardiac muscle cell	4 studies	24% ± 3%	Explore
hepatocyte	4 studies	43% ± 15%	Explore
muscle cell	4 studies	32% ± 13%	Explore
enteroendocrine cell	4 studies	33% ± 11%	Explore
erythrocyte	4 studies	38% ± 17%	Explore
keratinocyte	4 studies	21% ± 3%	Explore
T-helper 17 cell	4 studies	27% ± 5%	Explore
double negative thymocyte	4 studies	47% ± 11%	Explore
CD4-positive, alpha-beta cytotoxic T cell	3 studies	32% ± 10%	Explore
platelet	3 studies	17% ± 1%	Explore
type B pancreatic cell	3 studies	42% ± 20%	Explore
glomerular endothelial cell	3 studies	38% ± 4%	Explore
epithelial cell of proximal tubule	3 studies	20% ± 3%	Explore
neural crest cell	3 studies	38% ± 4%	Explore
GABAergic interneuron	3 studies	33% ± 5%	Explore
placental villous trophoblast	3 studies	24% ± 7%	Explore
erythroblast	3 studies	57% ± 20%	Explore
retinal pigment epithelial cell	3 studies	38% ± 15%	Explore
tissue-resident macrophage	3 studies	23% ± 5%	Explore
GABAergic amacrine cell	3 studies	30% ± 2%	Explore
OFF-bipolar cell	3 studies	32% ± 6%	Explore
ON-bipolar cell	3 studies	32% ± 7%	Explore
glycinergic amacrine cell	3 studies	29% ± 4%	Explore
rod bipolar cell	3 studies	37% ± 8%	Explore
acinar cell	3 studies	34% ± 17%	Explore
germinal center B cell	3 studies	24% ± 7%	Explore
intermediate monocyte	3 studies	42% ± 22%	Explore
luminal hormone-sensing cell of mammary gland	3 studies	26% ± 3%	Explore
pancreatic ductal cell	3 studies	47% ± 24%	Explore
neural progenitor cell	3 studies	55% ± 14%	Explore
ependymal cell	3 studies	39% ± 19%	Explore
granulocyte	3 studies	27% ± 7%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	62% ± 14%	Explore
neutrophil	3 studies	18% ± 4%	Explore
intestinal crypt stem cell	3 studies	24% ± 5%	Explore
adventitial cell	3 studies	31% ± 3%	Explore
chondrocyte	3 studies	41% ± 8%	Explore
group 3 innate lymphoid cell	3 studies	46% ± 13%	Explore
melanocyte	3 studies	35% ± 13%	Explore
T-helper 1 cell	3 studies	38% ± 9%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	40% ± 7%	Explore
myoepithelial cell	3 studies	33% ± 12%	Explore
mural cell	3 studies	43% ± 12%	Explore
renal principal cell	3 studies	30% ± 6%	Explore
IgA plasma cell	3 studies	21% ± 8%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	19 studies	42% ± 20%	Explore
peripheral blood	18 studies	34% ± 10%	Explore
lung	17 studies	30% ± 11%	Explore
intestine	10 studies	27% ± 13%	Explore
eye	10 studies	30% ± 10%	Explore
kidney	8 studies	27% ± 7%	Explore
heart	5 studies	25% ± 4%	Explore
lymph node	5 studies	31% ± 5%	Explore
liver	5 studies	40% ± 17%	Explore
bone marrow	4 studies	34% ± 10%	Explore
uterus	4 studies	37% ± 14%	Explore
breast	4 studies	25% ± 6%	Explore
adipose	4 studies	45% ± 18%	Explore
pancreas	3 studies	43% ± 19%	Explore
skin	3 studies	20% ± 2%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
breast	100%	14832.88	459 / 459	100%	68.98	1118 / 1118
esophagus	100%	16155.89	1445 / 1445	100%	72.77	183 / 183
ovary	100%	23751.35	180 / 180	100%	58.06	430 / 430
prostate	100%	16524.98	245 / 245	100%	59.02	502 / 502
uterus	100%	23066.24	170 / 170	100%	79.87	459 / 459
lung	100%	15885.68	578 / 578	100%	61.56	1154 / 1155
bladder	100%	16354.62	21 / 21	100%	60.38	503 / 504
brain	100%	10193.40	2630 / 2642	100%	80.91	705 / 705
thymus	100%	20468.16	653 / 653	99%	70.66	601 / 605
stomach	100%	11983.47	359 / 359	99%	51.77	284 / 286
skin	100%	14447.07	1808 / 1809	99%	69.11	468 / 472
intestine	100%	17583.60	966 / 966	99%	48.71	521 / 527
kidney	100%	11502.55	89 / 89	99%	49.18	889 / 901
pancreas	99%	7776.00	326 / 328	99%	52.50	176 / 178
adrenal gland	100%	13190.90	258 / 258	97%	35.32	222 / 230
liver	100%	6783.04	225 / 226	91%	25.97	371 / 406
adipose	100%	15781.63	1204 / 1204	0%	0	0 / 0
blood vessel	100%	17061.67	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	50.21	29 / 29
muscle	100%	9310.83	803 / 803	0%	0	0 / 0
spleen	100%	16699.80	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	74.14	45 / 45
ureter	0%	0	0 / 0	100%	28.43	1 / 1
heart	98%	8303.43	841 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	94%	32.41	75 / 80
peripheral blood	78%	6563.15	722 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

IV. Literature review

[source]

Gene name	HP1BP3
Protein name	Heterochromatin protein 1 binding protein 3 Heterochromatin protein 1-binding protein 3 Heterochromatin protein 1-binding protein 3 (Protein HP1-BP74) Alternative protein HP1BP3
Synonyms	hCG_38870
Description	FUNCTION: Component of heterochromatin that maintains heterochromatin integrity during G1/S progression and regulates the duration of G1 phase to critically influence cell proliferative capacity . Mediates chromatin condensation during hypoxia, leading to increased tumor cell viability, radio-resistance, chemo-resistance and self-renewal. .
Accessions	ENST00000419948.5 Q5SSJ5 ENST00000312239.10 [Q5SSJ5-1] B0QZK5 B0QZK9 ENST00000375003.6 [Q5SSJ5-3] ENST00000375000.5 [Q5SSJ5-5] ENST00000414993.1 B0QZK6 B4E0N8 B0QZK8 ENST00000417710.5 ENST00000437575.5 ENST00000419490.5 B0QZK7 ENST00000443615.1 B0QZK4 L8E9W8 Q5SWC8 ENST00000424732.5 ENST00000438032.6 [Q5SSJ5-1]

GO_0070828	Biological process	heterochromatin organization
GO_0097298	Biological process	regulation of nucleus size
GO_0042127	Biological process	regulation of cell population proliferation
GO_0006355	Biological process	regulation of DNA-templated transcription
GO_0071456	Biological process	cellular response to hypoxia
GO_0006334	Biological process	nucleosome assembly
GO_0016607	Cellular component	nuclear speck
GO_0005694	Cellular component	chromosome
GO_0000786	Cellular component	nucleosome
GO_0005634	Cellular component	nucleus
GO_0031491	Molecular function	nucleosome binding
GO_0003677	Molecular function	DNA binding
GO_0005515	Molecular function	protein binding

HP1BP3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review