CCNL1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	47 studies	44% ± 19%	Explore
fibroblast	42 studies	43% ± 19%	Explore
B cell	41 studies	42% ± 16%	Explore
macrophage	38 studies	40% ± 15%	Explore
natural killer cell	38 studies	39% ± 14%	Explore
CD8-positive, alpha-beta T cell	35 studies	37% ± 13%	Explore
CD4-positive, alpha-beta T cell	33 studies	40% ± 15%	Explore
T cell	32 studies	40% ± 16%	Explore
pericyte	30 studies	41% ± 19%	Explore
smooth muscle cell	28 studies	39% ± 18%	Explore
conventional dendritic cell	28 studies	46% ± 18%	Explore
classical monocyte	27 studies	51% ± 18%	Explore
regulatory T cell	27 studies	41% ± 15%	Explore
endothelial cell of lymphatic vessel	23 studies	42% ± 18%	Explore
non-classical monocyte	23 studies	47% ± 17%	Explore
basal cell	23 studies	41% ± 16%	Explore
monocyte	22 studies	44% ± 15%	Explore
dendritic cell	20 studies	47% ± 24%	Explore
mast cell	20 studies	38% ± 13%	Explore
mature NK T cell	20 studies	38% ± 13%	Explore
memory B cell	20 studies	43% ± 12%	Explore
naive B cell	20 studies	39% ± 13%	Explore
plasmacytoid dendritic cell	20 studies	52% ± 19%	Explore
epithelial cell	20 studies	47% ± 22%	Explore
plasma cell	18 studies	39% ± 12%	Explore
gamma-delta T cell	18 studies	43% ± 16%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	18 studies	39% ± 14%	Explore
ciliated cell	18 studies	34% ± 18%	Explore
connective tissue cell	17 studies	42% ± 13%	Explore
CD16-negative, CD56-bright natural killer cell, human	16 studies	45% ± 19%	Explore
myeloid cell	16 studies	41% ± 18%	Explore
mucosal invariant T cell	15 studies	45% ± 14%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	15 studies	41% ± 14%	Explore
CD16-positive, CD56-dim natural killer cell, human	15 studies	44% ± 17%	Explore
myofibroblast cell	15 studies	38% ± 17%	Explore
endothelial cell of vascular tree	14 studies	53% ± 17%	Explore
CD4-positive, alpha-beta memory T cell	13 studies	44% ± 15%	Explore
neutrophil	13 studies	42% ± 15%	Explore
capillary endothelial cell	13 studies	36% ± 9%	Explore
vein endothelial cell	13 studies	42% ± 16%	Explore
type II pneumocyte	12 studies	43% ± 17%	Explore
effector memory CD8-positive, alpha-beta T cell	12 studies	43% ± 19%	Explore
CD8-positive, alpha-beta memory T cell	12 studies	46% ± 16%	Explore
secretory cell	12 studies	47% ± 16%	Explore
endothelial cell of artery	12 studies	40% ± 13%	Explore
microglial cell	12 studies	33% ± 16%	Explore
astrocyte	12 studies	26% ± 12%	Explore
type I pneumocyte	11 studies	35% ± 17%	Explore
mesothelial cell	10 studies	36% ± 20%	Explore
plasmablast	9 studies	55% ± 23%	Explore
club cell	9 studies	39% ± 13%	Explore
leukocyte	9 studies	44% ± 15%	Explore
progenitor cell	9 studies	36% ± 18%	Explore
abnormal cell	9 studies	39% ± 11%	Explore
goblet cell	9 studies	38% ± 19%	Explore
adipocyte	9 studies	32% ± 8%	Explore
alveolar macrophage	8 studies	42% ± 9%	Explore
innate lymphoid cell	8 studies	42% ± 13%	Explore
oligodendrocyte	8 studies	24% ± 9%	Explore
effector CD8-positive, alpha-beta T cell	7 studies	34% ± 7%	Explore
enterocyte	7 studies	35% ± 14%	Explore
retinal rod cell	7 studies	27% ± 7%	Explore
precursor B cell	7 studies	53% ± 12%	Explore
T follicular helper cell	7 studies	54% ± 18%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	6 studies	30% ± 7%	Explore
hematopoietic precursor cell	6 studies	48% ± 22%	Explore
respiratory goblet cell	6 studies	36% ± 13%	Explore
effector CD4-positive, alpha-beta T cell	6 studies	39% ± 16%	Explore
mononuclear phagocyte	6 studies	49% ± 17%	Explore
IgA plasma cell	6 studies	27% ± 5%	Explore
IgG plasma cell	6 studies	26% ± 5%	Explore
lymphocyte	6 studies	46% ± 21%	Explore
immature B cell	6 studies	57% ± 7%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	48% ± 20%	Explore
CD4-positive helper T cell	5 studies	43% ± 18%	Explore
central memory CD8-positive, alpha-beta T cell	5 studies	38% ± 6%	Explore
platelet	5 studies	21% ± 4%	Explore
transit amplifying cell	5 studies	30% ± 23%	Explore
renal principal cell	5 studies	37% ± 18%	Explore
hematopoietic stem cell	5 studies	36% ± 10%	Explore
pro-B cell	5 studies	46% ± 9%	Explore
retinal pigment epithelial cell	5 studies	51% ± 17%	Explore
adventitial cell	5 studies	41% ± 15%	Explore
Mueller cell	5 studies	34% ± 11%	Explore
intermediate monocyte	5 studies	58% ± 18%	Explore
oligodendrocyte precursor cell	5 studies	35% ± 11%	Explore
ionocyte	4 studies	30% ± 8%	Explore
squamous epithelial cell	4 studies	41% ± 21%	Explore
pancreatic A cell	4 studies	31% ± 13%	Explore
exhausted T cell	4 studies	49% ± 21%	Explore
kidney distal convoluted tubule epithelial cell	4 studies	40% ± 6%	Explore
epithelial cell of proximal tubule	4 studies	26% ± 7%	Explore
enteroendocrine cell	4 studies	38% ± 14%	Explore
intestinal crypt stem cell	4 studies	23% ± 6%	Explore
kidney loop of Henle epithelial cell	4 studies	29% ± 15%	Explore
retinal cone cell	4 studies	35% ± 14%	Explore
glial cell	4 studies	31% ± 13%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	53% ± 13%	Explore
hepatocyte	4 studies	52% ± 23%	Explore
granulocyte	4 studies	36% ± 7%	Explore
luminal cell of prostate epithelium	4 studies	42% ± 14%	Explore
GABAergic neuron	4 studies	30% ± 8%	Explore
mucus secreting cell	4 studies	19% ± 2%	Explore
group 3 innate lymphoid cell	4 studies	62% ± 14%	Explore
T-helper 17 cell	4 studies	36% ± 15%	Explore
double negative thymocyte	4 studies	50% ± 21%	Explore
CD4-positive, alpha-beta cytotoxic T cell	3 studies	30% ± 9%	Explore
type B pancreatic cell	3 studies	34% ± 10%	Explore
monocyte-derived dendritic cell	3 studies	47% ± 28%	Explore
glomerular endothelial cell	3 studies	44% ± 7%	Explore
renal alpha-intercalated cell	3 studies	47% ± 24%	Explore
neural crest cell	3 studies	26% ± 7%	Explore
retinal bipolar neuron	3 studies	27% ± 8%	Explore
extravillous trophoblast	3 studies	21% ± 5%	Explore
placental villous trophoblast	3 studies	27% ± 3%	Explore
retina horizontal cell	3 studies	25% ± 6%	Explore
duct epithelial cell	3 studies	27% ± 3%	Explore
tissue-resident macrophage	3 studies	60% ± 20%	Explore
inflammatory macrophage	3 studies	40% ± 19%	Explore
acinar cell	3 studies	39% ± 16%	Explore
germinal center B cell	3 studies	36% ± 6%	Explore
endothelial cell of sinusoid	3 studies	23% ± 6%	Explore
muscle cell	3 studies	45% ± 1%	Explore
glutamatergic neuron	3 studies	44% ± 7%	Explore
pancreatic ductal cell	3 studies	50% ± 18%	Explore
brush cell	3 studies	23% ± 6%	Explore
melanocyte	3 studies	44% ± 16%	Explore
keratinocyte	3 studies	44% ± 13%	Explore
neuron	3 studies	32% ± 10%	Explore
T-helper 1 cell	3 studies	49% ± 19%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	43% ± 12%	Explore
double-positive, alpha-beta thymocyte	3 studies	61% ± 21%	Explore
myoepithelial cell	3 studies	55% ± 16%	Explore
progenitor cell of mammary luminal epithelium	3 studies	50% ± 13%	Explore
erythrocyte	3 studies	43% ± 11%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	20 studies	38% ± 14%	Explore
peripheral blood	19 studies	44% ± 18%	Explore
intestine	10 studies	40% ± 15%	Explore
kidney	9 studies	29% ± 11%	Explore
eye	9 studies	34% ± 16%	Explore
brain	8 studies	35% ± 13%	Explore
liver	6 studies	38% ± 10%	Explore
placenta	5 studies	26% ± 7%	Explore
uterus	5 studies	56% ± 19%	Explore
adipose	5 studies	30% ± 8%	Explore
prostate	5 studies	36% ± 14%	Explore
lymph node	5 studies	41% ± 12%	Explore
breast	5 studies	46% ± 10%	Explore
pancreas	4 studies	32% ± 15%	Explore
bone marrow	4 studies	33% ± 11%	Explore
esophagus	4 studies	35% ± 17%	Explore
skin	4 studies	35% ± 12%	Explore
heart	3 studies	18% ± 3%	Explore
adrenal gland	3 studies	29% ± 9%	Explore
thymus	3 studies	46% ± 21%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	7202.52	1445 / 1445	100%	51.83	183 / 183
breast	100%	12024.59	459 / 459	100%	29.17	1117 / 1118
bladder	100%	7883.48	21 / 21	100%	34.05	502 / 504
uterus	100%	9609.66	170 / 170	100%	43.71	457 / 459
ovary	100%	11668.82	180 / 180	99%	26.08	427 / 430
intestine	100%	9220.16	966 / 966	99%	26.16	523 / 527
lung	100%	16106.97	578 / 578	99%	37.02	1146 / 1155
stomach	100%	7067.80	358 / 359	99%	27.99	284 / 286
thymus	100%	11894.95	653 / 653	99%	32.26	599 / 605
prostate	100%	9889.67	245 / 245	99%	30.68	497 / 502
pancreas	100%	4840.65	328 / 328	98%	34.66	175 / 178
kidney	100%	8141.19	89 / 89	97%	24.20	870 / 901
adrenal gland	100%	7397.35	258 / 258	97%	16.39	222 / 230
liver	100%	7298.31	226 / 226	94%	17.47	382 / 406
skin	100%	9189.71	1809 / 1809	90%	21.05	426 / 472
brain	87%	3286.89	2305 / 2642	100%	22.04	702 / 705
adipose	100%	13873.04	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	31.51	29 / 29
spleen	100%	13405.01	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	35.35	45 / 45
ureter	0%	0	0 / 0	100%	8.51	1 / 1
blood vessel	100%	6919.62	1330 / 1335	0%	0	0 / 0
peripheral blood	96%	6271.02	896 / 929	0%	0	0 / 0
heart	94%	4372.72	807 / 861	0%	0	0 / 0
muscle	92%	3534.51	740 / 803	0%	0	0 / 0
eye	0%	0	0 / 0	57%	9.01	46 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

IV. Literature review

[source]

Gene name	CCNL1
Protein name	Cyclin L1 Cyclin-L1 (Cyclin-L)
Synonyms	UNQ530/PRO1073 BM-001
Description	FUNCTION: Involved in pre-mRNA splicing. Functions in association with cyclin-dependent kinases (CDKs) . Inhibited by the CDK-specific inhibitor CDKN1A/p21 . May play a role in the regulation of RNA polymerase II (pol II). May be a candidate proto-oncogene in head and neck squamous cell carcinomas (HNSCC) . .
Accessions	ENST00000477127.5 [Q9UK58-5] ENST00000295925.5 [Q9UK58-5] ENST00000631619.1 [Q9UK58-5] H7C4G1 ENST00000465947.5 [Q9UK58-5] Q9UK58 ENST00000475298.5 [Q9UK58-5] ENST00000468977.5 ENST00000461804.5 [Q9UK58-6] ENST00000295926.8 [Q9UK58-1] ENST00000470121.5 [Q9UK58-4]

GO_0043484	Biological process	regulation of RNA splicing
GO_0042981	Biological process	regulation of apoptotic process
GO_0051726	Biological process	regulation of cell cycle
GO_0046605	Biological process	regulation of centrosome cycle
GO_0006357	Biological process	regulation of transcription by RNA polymerase II
GO_0016607	Cellular component	nuclear speck
GO_0000307	Cellular component	cyclin-dependent protein kinase holoenzyme complex
GO_0005634	Cellular component	nucleus
GO_0016538	Molecular function	cyclin-dependent protein serine/threonine kinase regulator activity
GO_0005515	Molecular function	protein binding

CCNL1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review