Name | Number of supported studies | Average coverage | |
---|---|---|---|
lung | 20 studies | 52% ± 17% | |
peripheral blood | 19 studies | 50% ± 14% | |
intestine | 12 studies | 36% ± 14% | |
kidney | 9 studies | 51% ± 12% | |
brain | 9 studies | 37% ± 15% | |
liver | 7 studies | 43% ± 18% | |
lymph node | 6 studies | 45% ± 22% | |
pancreas | 5 studies | 59% ± 25% | |
bone marrow | 5 studies | 37% ± 13% | |
uterus | 5 studies | 54% ± 21% | |
prostate | 5 studies | 40% ± 13% | |
placenta | 4 studies | 65% ± 28% | |
eye | 4 studies | 31% ± 13% | |
heart | 4 studies | 22% ± 6% | |
adipose | 4 studies | 30% ± 13% | |
breast | 4 studies | 51% ± 6% | |
adrenal gland | 3 studies | 39% ± 6% | |
esophagus | 3 studies | 52% ± 25% | |
skin | 3 studies | 39% ± 10% | |
stomach | 3 studies | 31% ± 21% | |
thymus | 3 studies | 48% ± 13% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 7087.24 | 1445 / 1445 | 100% | 245.28 | 183 / 183 |
kidney | 100% | 10447.10 | 89 / 89 | 100% | 356.80 | 901 / 901 |
lung | 100% | 9093.89 | 578 / 578 | 100% | 345.05 | 1155 / 1155 |
ovary | 100% | 6274.67 | 180 / 180 | 100% | 318.30 | 430 / 430 |
prostate | 100% | 8257.65 | 245 / 245 | 100% | 416.58 | 502 / 502 |
skin | 100% | 7243.33 | 1809 / 1809 | 100% | 312.33 | 472 / 472 |
stomach | 100% | 6491.75 | 359 / 359 | 100% | 262.78 | 286 / 286 |
uterus | 100% | 6665.98 | 170 / 170 | 100% | 315.30 | 459 / 459 |
thymus | 100% | 9073.64 | 653 / 653 | 100% | 416.57 | 604 / 605 |
intestine | 100% | 6750.70 | 966 / 966 | 100% | 289.24 | 526 / 527 |
breast | 100% | 8275.91 | 459 / 459 | 100% | 391.23 | 1115 / 1118 |
pancreas | 100% | 3637.11 | 327 / 328 | 100% | 338.79 | 178 / 178 |
adrenal gland | 100% | 9052.95 | 258 / 258 | 100% | 470.03 | 229 / 230 |
liver | 100% | 4256.88 | 225 / 226 | 100% | 273.42 | 406 / 406 |
bladder | 100% | 7949.86 | 21 / 21 | 99% | 303.99 | 501 / 504 |
brain | 87% | 2673.32 | 2292 / 2642 | 100% | 291.92 | 705 / 705 |
adipose | 100% | 8617.71 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 8065.26 | 1335 / 1335 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 295.99 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 519.76 | 29 / 29 |
spleen | 100% | 8842.88 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 293.46 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 111.78 | 1 / 1 |
peripheral blood | 100% | 17128.06 | 926 / 929 | 0% | 0 | 0 / 0 |
muscle | 99% | 4624.69 | 796 / 803 | 0% | 0 | 0 / 0 |
heart | 99% | 5963.57 | 850 / 861 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0007035 | Biological process | vacuolar acidification |
GO_1902600 | Biological process | proton transmembrane transport |
GO_0055085 | Biological process | transmembrane transport |
GO_0016241 | Biological process | regulation of macroautophagy |
GO_0010008 | Cellular component | endosome membrane |
GO_0033179 | Cellular component | proton-transporting V-type ATPase, V0 domain |
GO_0005765 | Cellular component | lysosomal membrane |
GO_0030670 | Cellular component | phagocytic vesicle membrane |
GO_0046961 | Molecular function | proton-transporting ATPase activity, rotational mechanism |
GO_0042625 | Molecular function | ATPase-coupled ion transmembrane transporter activity |
GO_0005515 | Molecular function | protein binding |
Gene name | ATP6V0E1 |
Protein name | V-type proton ATPase subunit e 1 (V-ATPase subunit e 1) (V-ATPase 9.2 kDa membrane accessory protein) (V-ATPase M9.2 subunit) (Vacuolar proton pump subunit e 1) ATPase H+ transporting V0 subunit e1 |
Synonyms | ATP6H ATP6V0E |
Description | FUNCTION: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons . V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity). . |
Accessions | J3KN48 ENST00000519374.6 ENST00000265093.4 O15342 ENST00000517669.1 E5RHL5 ENST00000519911.5 |