ATP5ME | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	38 studies	49% ± 21%	Explore
B cell	37 studies	40% ± 16%	Explore
natural killer cell	35 studies	46% ± 14%	Explore
macrophage	33 studies	52% ± 19%	Explore
CD8-positive, alpha-beta T cell	33 studies	41% ± 14%	Explore
fibroblast	32 studies	51% ± 19%	Explore
T cell	29 studies	43% ± 16%	Explore
CD4-positive, alpha-beta T cell	29 studies	41% ± 13%	Explore
pericyte	27 studies	56% ± 20%	Explore
conventional dendritic cell	26 studies	56% ± 19%	Explore
classical monocyte	25 studies	52% ± 16%	Explore
smooth muscle cell	24 studies	54% ± 18%	Explore
epithelial cell	23 studies	57% ± 25%	Explore
dendritic cell	22 studies	47% ± 23%	Explore
plasma cell	22 studies	49% ± 19%	Explore
non-classical monocyte	22 studies	50% ± 17%	Explore
regulatory T cell	22 studies	39% ± 9%	Explore
basal cell	20 studies	52% ± 23%	Explore
monocyte	19 studies	55% ± 21%	Explore
mature NK T cell	19 studies	39% ± 12%	Explore
plasmacytoid dendritic cell	19 studies	42% ± 14%	Explore
mast cell	18 studies	41% ± 14%	Explore
memory B cell	18 studies	37% ± 11%	Explore
connective tissue cell	17 studies	50% ± 22%	Explore
endothelial cell of lymphatic vessel	16 studies	63% ± 15%	Explore
naive B cell	16 studies	35% ± 10%	Explore
ciliated cell	15 studies	74% ± 17%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	15 studies	34% ± 11%	Explore
gamma-delta T cell	15 studies	44% ± 19%	Explore
CD16-positive, CD56-dim natural killer cell, human	14 studies	45% ± 13%	Explore
capillary endothelial cell	14 studies	39% ± 16%	Explore
myeloid cell	14 studies	52% ± 20%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	13 studies	41% ± 12%	Explore
astrocyte	13 studies	33% ± 17%	Explore
mucosal invariant T cell	13 studies	31% ± 9%	Explore
CD16-negative, CD56-bright natural killer cell, human	12 studies	39% ± 14%	Explore
plasmablast	12 studies	52% ± 20%	Explore
oligodendrocyte	12 studies	33% ± 16%	Explore
myofibroblast cell	12 studies	56% ± 20%	Explore
endothelial cell of artery	12 studies	44% ± 20%	Explore
CD8-positive, alpha-beta memory T cell	11 studies	43% ± 10%	Explore
secretory cell	11 studies	52% ± 22%	Explore
goblet cell	11 studies	62% ± 25%	Explore
CD4-positive, alpha-beta memory T cell	10 studies	36% ± 12%	Explore
progenitor cell	10 studies	71% ± 18%	Explore
abnormal cell	10 studies	48% ± 18%	Explore
mesothelial cell	10 studies	60% ± 19%	Explore
vein endothelial cell	10 studies	49% ± 18%	Explore
endothelial cell of vascular tree	10 studies	42% ± 11%	Explore
type I pneumocyte	8 studies	55% ± 19%	Explore
leukocyte	8 studies	46% ± 18%	Explore
effector memory CD8-positive, alpha-beta T cell	8 studies	45% ± 10%	Explore
neuron	8 studies	51% ± 21%	Explore
retinal rod cell	8 studies	53% ± 19%	Explore
type II pneumocyte	7 studies	56% ± 21%	Explore
club cell	7 studies	63% ± 14%	Explore
epithelial cell of proximal tubule	7 studies	73% ± 15%	Explore
innate lymphoid cell	7 studies	49% ± 16%	Explore
enterocyte	7 studies	73% ± 24%	Explore
T follicular helper cell	7 studies	46% ± 16%	Explore
glutamatergic neuron	7 studies	31% ± 16%	Explore
microglial cell	7 studies	43% ± 20%	Explore
retinal cone cell	7 studies	59% ± 30%	Explore
hematopoietic precursor cell	6 studies	51% ± 20%	Explore
ionocyte	6 studies	60% ± 14%	Explore
respiratory goblet cell	6 studies	53% ± 18%	Explore
effector CD8-positive, alpha-beta T cell	6 studies	46% ± 9%	Explore
mononuclear phagocyte	6 studies	53% ± 21%	Explore
kidney loop of Henle epithelial cell	6 studies	73% ± 16%	Explore
neutrophil	6 studies	44% ± 17%	Explore
renal alpha-intercalated cell	6 studies	83% ± 5%	Explore
erythroblast	6 studies	58% ± 27%	Explore
IgG plasma cell	6 studies	34% ± 14%	Explore
precursor B cell	6 studies	53% ± 12%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	40% ± 13%	Explore
exhausted T cell	5 studies	48% ± 9%	Explore
effector CD4-positive, alpha-beta T cell	5 studies	41% ± 13%	Explore
kidney distal convoluted tubule epithelial cell	5 studies	87% ± 3%	Explore
enteroendocrine cell	5 studies	84% ± 12%	Explore
intestinal crypt stem cell	5 studies	64% ± 33%	Explore
IgA plasma cell	5 studies	35% ± 13%	Explore
transit amplifying cell	5 studies	69% ± 28%	Explore
retinal ganglion cell	5 studies	68% ± 30%	Explore
hematopoietic stem cell	5 studies	39% ± 13%	Explore
brush cell	5 studies	66% ± 20%	Explore
neuroendocrine cell	5 studies	74% ± 16%	Explore
immature B cell	5 studies	50% ± 13%	Explore
amacrine cell	5 studies	53% ± 21%	Explore
erythrocyte	5 studies	53% ± 20%	Explore
double negative thymocyte	5 studies	53% ± 19%	Explore
intermediate monocyte	5 studies	62% ± 20%	Explore
alveolar macrophage	4 studies	60% ± 13%	Explore
deuterosomal cell	4 studies	62% ± 16%	Explore
glomerular endothelial cell	4 studies	55% ± 12%	Explore
podocyte	4 studies	76% ± 8%	Explore
OFF-bipolar cell	4 studies	51% ± 30%	Explore
ON-bipolar cell	4 studies	54% ± 27%	Explore
pro-B cell	4 studies	54% ± 13%	Explore
retina horizontal cell	4 studies	50% ± 21%	Explore
mucus secreting cell	4 studies	58% ± 22%	Explore
cardiac muscle cell	4 studies	36% ± 18%	Explore
Mueller cell	4 studies	48% ± 17%	Explore
CD4-positive helper T cell	4 studies	30% ± 8%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	58% ± 17%	Explore
granulocyte	4 studies	44% ± 19%	Explore
GABAergic neuron	4 studies	30% ± 13%	Explore
oligodendrocyte precursor cell	4 studies	49% ± 10%	Explore
glial cell	4 studies	47% ± 26%	Explore
hepatocyte	4 studies	62% ± 35%	Explore
group 3 innate lymphoid cell	4 studies	50% ± 15%	Explore
duct epithelial cell	3 studies	63% ± 6%	Explore
precursor cell	3 studies	50% ± 18%	Explore
squamous epithelial cell	3 studies	41% ± 28%	Explore
platelet	3 studies	31% ± 11%	Explore
pancreatic A cell	3 studies	79% ± 7%	Explore
type B pancreatic cell	3 studies	79% ± 4%	Explore
renal beta-intercalated cell	3 studies	84% ± 3%	Explore
renal intercalated cell	3 studies	82% ± 6%	Explore
neural crest cell	3 studies	66% ± 10%	Explore
retinal bipolar neuron	3 studies	67% ± 31%	Explore
GABAergic amacrine cell	3 studies	29% ± 12%	Explore
glycinergic amacrine cell	3 studies	29% ± 12%	Explore
renal principal cell	3 studies	78% ± 6%	Explore
extravillous trophoblast	3 studies	44% ± 9%	Explore
placental villous trophoblast	3 studies	66% ± 19%	Explore
lymphocyte	3 studies	61% ± 10%	Explore
retinal pigment epithelial cell	3 studies	61% ± 28%	Explore
adventitial cell	3 studies	36% ± 3%	Explore
tissue-resident macrophage	3 studies	38% ± 21%	Explore
intraepithelial lymphocyte	3 studies	47% ± 20%	Explore
rod bipolar cell	3 studies	58% ± 21%	Explore
acinar cell	3 studies	46% ± 15%	Explore
muscle cell	3 studies	46% ± 24%	Explore
germinal center B cell	3 studies	62% ± 3%	Explore
myoepithelial cell	3 studies	35% ± 16%	Explore
luminal cell of prostate epithelium	3 studies	42% ± 14%	Explore
IgM plasma cell	3 studies	37% ± 17%	Explore
granulocyte monocyte progenitor cell	3 studies	51% ± 22%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	68% ± 9%	Explore
keratinocyte	3 studies	59% ± 4%	Explore
T-helper 17 cell	3 studies	39% ± 9%	Explore
interneuron	3 studies	28% ± 3%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	34% ± 12%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	38% ± 4%	Explore
central memory CD8-positive, alpha-beta T cell	3 studies	34% ± 11%	Explore
progenitor cell of mammary luminal epithelium	3 studies	39% ± 16%	Explore
T-helper 1 cell	3 studies	42% ± 8%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	19 studies	44% ± 15%	Explore
lung	17 studies	57% ± 19%	Explore
brain	15 studies	32% ± 14%	Explore
intestine	12 studies	51% ± 25%	Explore
eye	10 studies	50% ± 17%	Explore
kidney	9 studies	56% ± 17%	Explore
bone marrow	7 studies	35% ± 14%	Explore
liver	7 studies	52% ± 24%	Explore
lymph node	5 studies	41% ± 8%	Explore
uterus	5 studies	57% ± 24%	Explore
pancreas	4 studies	63% ± 20%	Explore
placenta	4 studies	51% ± 16%	Explore
prostate	4 studies	31% ± 11%	Explore
breast	4 studies	44% ± 13%	Explore
heart	3 studies	35% ± 12%	Explore
adrenal gland	3 studies	48% ± 3%	Explore
esophagus	3 studies	60% ± 28%	Explore
skin	3 studies	46% ± 11%	Explore
thymus	3 studies	56% ± 15%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
ovary	100%	1004.74	180 / 180	100%	70.61	430 / 430
intestine	100%	1626.10	966 / 966	100%	81.40	525 / 527
esophagus	100%	1525.02	1445 / 1445	99%	37.00	182 / 183
brain	100%	1848.01	2641 / 2642	99%	39.98	701 / 705
adrenal gland	100%	1563.41	258 / 258	99%	46.75	228 / 230
bladder	100%	1235.43	21 / 21	99%	59.90	498 / 504
uterus	100%	985.16	170 / 170	99%	51.98	453 / 459
stomach	100%	1255.59	359 / 359	99%	61.48	282 / 286
kidney	100%	1846.67	89 / 89	98%	37.56	886 / 901
prostate	100%	1135.48	244 / 245	98%	43.38	492 / 502
liver	100%	1236.65	226 / 226	98%	43.56	396 / 406
breast	100%	1100.40	459 / 459	97%	32.98	1088 / 1118
skin	100%	1109.02	1808 / 1809	96%	26.00	455 / 472
pancreas	99%	712.10	326 / 328	96%	37.71	170 / 178
lung	99%	977.12	575 / 578	95%	27.30	1099 / 1155
thymus	100%	1187.42	653 / 653	92%	34.49	559 / 605
eye	0%	0	0 / 0	100%	44.33	80 / 80
lymph node	0%	0	0 / 0	100%	59.04	29 / 29
spleen	100%	1130.25	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	82.13	1 / 1
heart	100%	3365.58	860 / 861	0%	0	0 / 0
adipose	100%	1143.10	1201 / 1204	0%	0	0 / 0
blood vessel	100%	1149.58	1331 / 1335	0%	0	0 / 0
muscle	100%	2123.27	800 / 803	0%	0	0 / 0
tonsil	0%	0	0 / 0	89%	38.92	40 / 45
peripheral blood	53%	522.30	489 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

IV. Literature review

[source]

Gene name	ATP5ME
Protein name	ATP synthase subunit e, mitochondrial (ATPase subunit e) (ATP synthase membrane subunit e) [Cleaved into: ATP synthase subunit e, mitochondrial, N-terminally processed]
Synonyms	ATP5K ATP5I
Description	FUNCTION: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
Accessions	ENST00000304312.5 P56385

GO_0042776	Biological process	proton motive force-driven mitochondrial ATP synthesis
GO_1902600	Biological process	proton transmembrane transport
GO_0015986	Biological process	proton motive force-driven ATP synthesis
GO_0005753	Cellular component	mitochondrial proton-transporting ATP synthase complex
GO_0000276	Cellular component	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
GO_0005743	Cellular component	mitochondrial inner membrane
GO_0005739	Cellular component	mitochondrion
GO_0046933	Molecular function	proton-transporting ATP synthase activity, rotational mechanism
GO_0005515	Molecular function	protein binding

ATP5ME report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review