ATP5MC2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_1902600Biological processproton transmembrane transport
GO_0015986Biological processproton motive force-driven ATP synthesis
GO_0005741Cellular componentmitochondrial outer membrane
GO_0005753Cellular componentmitochondrial proton-transporting ATP synthase complex
GO_0000276Cellular componentmitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
GO_0005743Cellular componentmitochondrial inner membrane
GO_0015078Molecular functionproton transmembrane transporter activity
GO_0005515Molecular functionprotein binding
GO_0008289Molecular functionlipid binding

IV. Literature review

[source]
Gene nameATP5MC2
Protein nameATP synthase membrane subunit c locus 2
ATP synthase F(0) complex subunit C2, mitochondrial (ATP synthase lipid-binding protein) (ATP synthase membrane subunit c locus 2) (ATP synthase proteolipid P2) (ATP synthase proton-transporting mitochondrial F(0) complex subunit C2) (ATPase protein 9) (ATPase subunit c)
SynonymsATP5G2
PSEC0033
DescriptionFUNCTION: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.

AccessionsF8W041
ENST00000549164.5 [Q06055-1]
Q06055
ENST00000673498.1 [Q06055-3]
ENST00000338662.6 [Q06055-1]
ENST00000552242.5 [Q06055-1]
ENST00000394349.9 [Q06055-1]
ENST00000549748.2