U2SURP | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	41 studies	29% ± 11%	Explore
B cell	34 studies	26% ± 8%	Explore
natural killer cell	33 studies	27% ± 9%	Explore
fibroblast	32 studies	26% ± 9%	Explore
pericyte	29 studies	25% ± 7%	Explore
CD8-positive, alpha-beta T cell	28 studies	26% ± 8%	Explore
CD4-positive, alpha-beta T cell	26 studies	25% ± 9%	Explore
smooth muscle cell	24 studies	24% ± 5%	Explore
T cell	23 studies	25% ± 6%	Explore
regulatory T cell	22 studies	28% ± 7%	Explore
macrophage	21 studies	26% ± 9%	Explore
memory B cell	19 studies	26% ± 7%	Explore
mast cell	17 studies	23% ± 6%	Explore
conventional dendritic cell	17 studies	26% ± 15%	Explore
astrocyte	17 studies	35% ± 17%	Explore
classical monocyte	16 studies	24% ± 11%	Explore
naive B cell	16 studies	28% ± 6%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	16 studies	28% ± 8%	Explore
non-classical monocyte	16 studies	27% ± 12%	Explore
CD16-positive, CD56-dim natural killer cell, human	15 studies	30% ± 8%	Explore
basal cell	15 studies	31% ± 15%	Explore
ciliated cell	15 studies	33% ± 13%	Explore
CD16-negative, CD56-bright natural killer cell, human	15 studies	29% ± 8%	Explore
capillary endothelial cell	15 studies	21% ± 4%	Explore
gamma-delta T cell	15 studies	31% ± 12%	Explore
endothelial cell of lymphatic vessel	14 studies	29% ± 7%	Explore
mature NK T cell	14 studies	26% ± 6%	Explore
oligodendrocyte precursor cell	14 studies	37% ± 16%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	13 studies	31% ± 8%	Explore
oligodendrocyte	13 studies	38% ± 16%	Explore
epithelial cell	13 studies	37% ± 20%	Explore
monocyte	12 studies	22% ± 5%	Explore
CD8-positive, alpha-beta memory T cell	12 studies	30% ± 8%	Explore
vein endothelial cell	12 studies	22% ± 9%	Explore
mucosal invariant T cell	12 studies	27% ± 5%	Explore
plasmacytoid dendritic cell	12 studies	30% ± 7%	Explore
plasma cell	11 studies	26% ± 12%	Explore
effector memory CD8-positive, alpha-beta T cell	11 studies	28% ± 10%	Explore
myofibroblast cell	11 studies	27% ± 6%	Explore
connective tissue cell	11 studies	28% ± 7%	Explore
microglial cell	11 studies	31% ± 10%	Explore
dendritic cell	10 studies	31% ± 19%	Explore
CD4-positive, alpha-beta memory T cell	10 studies	28% ± 5%	Explore
GABAergic neuron	10 studies	39% ± 21%	Explore
glutamatergic neuron	10 studies	42% ± 23%	Explore
type I pneumocyte	9 studies	27% ± 7%	Explore
endothelial cell of vascular tree	9 studies	27% ± 9%	Explore
adipocyte	9 studies	30% ± 11%	Explore
endothelial cell of artery	8 studies	23% ± 2%	Explore
club cell	8 studies	25% ± 8%	Explore
plasmablast	7 studies	49% ± 21%	Explore
secretory cell	7 studies	30% ± 14%	Explore
progenitor cell	7 studies	28% ± 6%	Explore
abnormal cell	7 studies	38% ± 9%	Explore
neuron	7 studies	37% ± 13%	Explore
amacrine cell	7 studies	34% ± 12%	Explore
myeloid cell	7 studies	27% ± 11%	Explore
type II pneumocyte	7 studies	24% ± 8%	Explore
retinal rod cell	7 studies	31% ± 8%	Explore
effector CD8-positive, alpha-beta T cell	6 studies	31% ± 8%	Explore
leukocyte	6 studies	31% ± 5%	Explore
interneuron	6 studies	50% ± 20%	Explore
lymphocyte	6 studies	30% ± 11%	Explore
precursor B cell	6 studies	35% ± 8%	Explore
retina horizontal cell	6 studies	34% ± 11%	Explore
T follicular helper cell	6 studies	26% ± 6%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	29% ± 10%	Explore
hematopoietic precursor cell	5 studies	41% ± 14%	Explore
respiratory goblet cell	5 studies	24% ± 9%	Explore
effector CD4-positive, alpha-beta T cell	5 studies	29% ± 6%	Explore
erythroblast	5 studies	40% ± 23%	Explore
hematopoietic stem cell	5 studies	35% ± 9%	Explore
pro-B cell	5 studies	39% ± 7%	Explore
retinal cone cell	5 studies	33% ± 11%	Explore
cardiac muscle cell	5 studies	21% ± 3%	Explore
Mueller cell	5 studies	34% ± 8%	Explore
innate lymphoid cell	5 studies	26% ± 6%	Explore
mesothelial cell	5 studies	31% ± 12%	Explore
goblet cell	5 studies	32% ± 15%	Explore
mononuclear phagocyte	4 studies	26% ± 10%	Explore
exhausted T cell	4 studies	33% ± 12%	Explore
retinal bipolar neuron	4 studies	37% ± 11%	Explore
glial cell	4 studies	31% ± 12%	Explore
granule cell	4 studies	28% ± 9%	Explore
retinal ganglion cell	4 studies	29% ± 12%	Explore
brush cell	4 studies	31% ± 12%	Explore
immature B cell	4 studies	31% ± 5%	Explore
hepatocyte	4 studies	41% ± 18%	Explore
alveolar macrophage	4 studies	22% ± 7%	Explore
erythrocyte	4 studies	36% ± 18%	Explore
transit amplifying cell	4 studies	32% ± 25%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	28% ± 5%	Explore
ionocyte	3 studies	36% ± 8%	Explore
pancreatic A cell	3 studies	35% ± 12%	Explore
type B pancreatic cell	3 studies	40% ± 17%	Explore
glomerular endothelial cell	3 studies	24% ± 3%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	21% ± 2%	Explore
differentiation-committed oligodendrocyte precursor	3 studies	43% ± 9%	Explore
neural crest cell	3 studies	32% ± 2%	Explore
GABAergic interneuron	3 studies	30% ± 7%	Explore
retinal pigment epithelial cell	3 studies	40% ± 18%	Explore
OFF-bipolar cell	3 studies	29% ± 10%	Explore
ON-bipolar cell	3 studies	31% ± 11%	Explore
glycinergic amacrine cell	3 studies	24% ± 5%	Explore
rod bipolar cell	3 studies	41% ± 8%	Explore
germinal center B cell	3 studies	22% ± 4%	Explore
CD4-positive helper T cell	3 studies	24% ± 5%	Explore
luminal hormone-sensing cell of mammary gland	3 studies	20% ± 4%	Explore
myoepithelial cell	3 studies	29% ± 3%	Explore
muscle cell	3 studies	36% ± 19%	Explore
pancreatic ductal cell	3 studies	36% ± 15%	Explore
ependymal cell	3 studies	35% ± 14%	Explore
granulocyte	3 studies	23% ± 2%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	43% ± 24%	Explore
enteroendocrine cell	3 studies	27% ± 9%	Explore
intestinal crypt stem cell	3 studies	23% ± 5%	Explore
adventitial cell	3 studies	21% ± 4%	Explore
chondrocyte	3 studies	32% ± 3%	Explore
group 3 innate lymphoid cell	3 studies	33% ± 9%	Explore
T-helper 17 cell	3 studies	24% ± 2%	Explore
T-helper 1 cell	3 studies	28% ± 6%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	31% ± 6%	Explore
central memory CD8-positive, alpha-beta T cell	3 studies	29% ± 6%	Explore
double negative thymocyte	3 studies	45% ± 11%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	17 studies	37% ± 18%	Explore
lung	16 studies	26% ± 11%	Explore
peripheral blood	16 studies	31% ± 10%	Explore
eye	9 studies	33% ± 12%	Explore
intestine	6 studies	25% ± 11%	Explore
kidney	5 studies	23% ± 3%	Explore
lymph node	5 studies	25% ± 7%	Explore
liver	5 studies	34% ± 18%	Explore
bone marrow	4 studies	27% ± 7%	Explore
heart	4 studies	21% ± 1%	Explore
uterus	4 studies	32% ± 14%	Explore
adipose	4 studies	29% ± 6%	Explore
pancreas	3 studies	36% ± 13%	Explore
breast	3 studies	20% ± 3%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	5509.77	1445 / 1445	100%	47.70	183 / 183
lung	100%	5302.21	578 / 578	100%	39.45	1155 / 1155
breast	100%	6796.60	459 / 459	100%	36.31	1117 / 1118
ovary	100%	9148.24	180 / 180	100%	27.66	429 / 430
brain	100%	4507.42	2632 / 2642	100%	27.96	705 / 705
prostate	100%	6213.02	245 / 245	100%	26.18	500 / 502
uterus	100%	8054.94	170 / 170	100%	42.94	457 / 459
thymus	100%	6759.89	653 / 653	99%	28.50	600 / 605
bladder	100%	6130.14	21 / 21	99%	33.53	499 / 504
pancreas	100%	3617.18	328 / 328	98%	24.68	175 / 178
stomach	100%	4350.28	359 / 359	98%	32.03	279 / 286
intestine	100%	6016.67	966 / 966	97%	29.35	511 / 527
adrenal gland	100%	4402.84	258 / 258	97%	16.69	223 / 230
kidney	100%	3974.88	89 / 89	96%	23.27	868 / 901
skin	100%	6246.60	1809 / 1809	92%	28.85	433 / 472
liver	100%	2750.52	226 / 226	87%	13.87	352 / 406
blood vessel	100%	5958.15	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	30.87	29 / 29
muscle	100%	4399.84	803 / 803	0%	0	0 / 0
spleen	100%	6476.47	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	44.26	45 / 45
ureter	0%	0	0 / 0	100%	12.09	1 / 1
adipose	100%	6336.98	1203 / 1204	0%	0	0 / 0
heart	99%	3198.07	850 / 861	0%	0	0 / 0
peripheral blood	64%	3519.30	592 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	59%	8.88	47 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0006396	Biological process	RNA processing
GO_0005654	Cellular component	nucleoplasm
GO_0005634	Cellular component	nucleus
GO_0005515	Molecular function	protein binding
GO_0003723	Molecular function	RNA binding

Gene name	U2SURP
Protein name	U2 snRNP-associated SURP motif-containing protein (140 kDa Ser/Arg-rich domain protein) (U2-associated protein SR140) U2 snRNP associated SURP domain containing Alternative protein U2SURP
Synonyms	KIAA0332 SR140
Description
Accessions	ENST00000600150.5 E7ET15 ENST00000473835.7 [O15042-1] ENST00000493782.5 ENST00000463563.6 ENST00000493598.6 ENST00000488497.7 H0Y8D9 ENST00000467348.1 C9J5L1 U3KPT1 ENST00000465175.2 E7EW00 H7C4V2 O15042 L8E737 C9JDJ7

U2SURP report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review