TUBA1B | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
macrophage	43 studies	61% ± 23%	Explore
endothelial cell	43 studies	59% ± 20%	Explore
B cell	40 studies	47% ± 16%	Explore
fibroblast	38 studies	61% ± 21%	Explore
natural killer cell	37 studies	46% ± 20%	Explore
T cell	34 studies	49% ± 22%	Explore
pericyte	34 studies	64% ± 23%	Explore
CD8-positive, alpha-beta T cell	34 studies	48% ± 22%	Explore
CD4-positive, alpha-beta T cell	32 studies	47% ± 21%	Explore
conventional dendritic cell	31 studies	77% ± 13%	Explore
smooth muscle cell	28 studies	64% ± 23%	Explore
dendritic cell	26 studies	67% ± 21%	Explore
classical monocyte	26 studies	44% ± 17%	Explore
non-classical monocyte	25 studies	70% ± 13%	Explore
plasmacytoid dendritic cell	25 studies	65% ± 16%	Explore
regulatory T cell	25 studies	44% ± 18%	Explore
monocyte	24 studies	49% ± 21%	Explore
endothelial cell of lymphatic vessel	22 studies	69% ± 17%	Explore
mast cell	21 studies	53% ± 16%	Explore
basal cell	21 studies	53% ± 19%	Explore
mature NK T cell	20 studies	39% ± 10%	Explore
epithelial cell	20 studies	55% ± 20%	Explore
plasma cell	19 studies	41% ± 20%	Explore
gamma-delta T cell	19 studies	46% ± 15%	Explore
memory B cell	19 studies	46% ± 15%	Explore
naive B cell	19 studies	41% ± 13%	Explore
connective tissue cell	19 studies	64% ± 17%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	18 studies	34% ± 12%	Explore
ciliated cell	17 studies	50% ± 16%	Explore
capillary endothelial cell	17 studies	55% ± 22%	Explore
microglial cell	16 studies	50% ± 26%	Explore
CD16-negative, CD56-bright natural killer cell, human	15 studies	40% ± 16%	Explore
endothelial cell of artery	15 studies	56% ± 20%	Explore
mucosal invariant T cell	14 studies	37% ± 13%	Explore
CD16-positive, CD56-dim natural killer cell, human	14 studies	45% ± 11%	Explore
myofibroblast cell	14 studies	64% ± 20%	Explore
astrocyte	14 studies	37% ± 22%	Explore
vein endothelial cell	14 studies	59% ± 22%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	13 studies	35% ± 10%	Explore
myeloid cell	13 studies	67% ± 24%	Explore
CD8-positive, alpha-beta memory T cell	12 studies	47% ± 15%	Explore
secretory cell	12 studies	47% ± 15%	Explore
glutamatergic neuron	12 studies	61% ± 16%	Explore
endothelial cell of vascular tree	12 studies	73% ± 21%	Explore
innate lymphoid cell	11 studies	49% ± 17%	Explore
CD4-positive, alpha-beta memory T cell	11 studies	47% ± 16%	Explore
oligodendrocyte	11 studies	32% ± 10%	Explore
plasmablast	10 studies	63% ± 25%	Explore
effector memory CD8-positive, alpha-beta T cell	10 studies	43% ± 15%	Explore
progenitor cell	10 studies	63% ± 23%	Explore
abnormal cell	10 studies	66% ± 16%	Explore
erythrocyte	10 studies	53% ± 25%	Explore
platelet	9 studies	46% ± 14%	Explore
leukocyte	9 studies	61% ± 20%	Explore
neuron	9 studies	67% ± 18%	Explore
goblet cell	9 studies	41% ± 14%	Explore
GABAergic neuron	9 studies	42% ± 19%	Explore
retinal rod cell	9 studies	60% ± 26%	Explore
type I pneumocyte	8 studies	50% ± 14%	Explore
type II pneumocyte	8 studies	45% ± 18%	Explore
effector CD8-positive, alpha-beta T cell	8 studies	57% ± 25%	Explore
mesothelial cell	8 studies	61% ± 23%	Explore
retinal ganglion cell	8 studies	72% ± 31%	Explore
hematopoietic stem cell	8 studies	73% ± 13%	Explore
oligodendrocyte precursor cell	8 studies	36% ± 21%	Explore
alveolar macrophage	7 studies	59% ± 21%	Explore
club cell	7 studies	44% ± 16%	Explore
mononuclear phagocyte	7 studies	55% ± 23%	Explore
epithelial cell of proximal tubule	7 studies	32% ± 20%	Explore
retinal cone cell	7 studies	71% ± 23%	Explore
precursor B cell	7 studies	58% ± 20%	Explore
T follicular helper cell	7 studies	40% ± 11%	Explore
interneuron	7 studies	52% ± 19%	Explore
respiratory goblet cell	6 studies	35% ± 21%	Explore
effector CD4-positive, alpha-beta T cell	6 studies	55% ± 11%	Explore
kidney loop of Henle epithelial cell	6 studies	32% ± 7%	Explore
renal alpha-intercalated cell	6 studies	49% ± 19%	Explore
megakaryocyte	6 studies	65% ± 27%	Explore
enterocyte	6 studies	32% ± 12%	Explore
erythroblast	6 studies	69% ± 30%	Explore
transit amplifying cell	6 studies	58% ± 29%	Explore
retina horizontal cell	6 studies	63% ± 23%	Explore
glial cell	6 studies	51% ± 17%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	53% ± 21%	Explore
CD4-positive helper T cell	5 studies	40% ± 17%	Explore
CD4-positive, alpha-beta cytotoxic T cell	5 studies	48% ± 21%	Explore
central memory CD8-positive, alpha-beta T cell	5 studies	37% ± 16%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	5 studies	40% ± 11%	Explore
hematopoietic precursor cell	5 studies	80% ± 15%	Explore
ionocyte	5 studies	39% ± 6%	Explore
amacrine cell	5 studies	61% ± 16%	Explore
pro-B cell	5 studies	61% ± 17%	Explore
immature B cell	5 studies	53% ± 17%	Explore
intermediate monocyte	5 studies	69% ± 18%	Explore
granulocyte	5 studies	59% ± 22%	Explore
deuterosomal cell	4 studies	78% ± 19%	Explore
precursor cell	4 studies	66% ± 28%	Explore
pancreatic A cell	4 studies	89% ± 11%	Explore
type B pancreatic cell	4 studies	82% ± 18%	Explore
monocyte-derived dendritic cell	4 studies	79% ± 6%	Explore
neutrophil	4 studies	33% ± 7%	Explore
glomerular endothelial cell	4 studies	52% ± 12%	Explore
kidney distal convoluted tubule epithelial cell	4 studies	59% ± 21%	Explore
enteroendocrine cell	4 studies	59% ± 19%	Explore
intestinal crypt stem cell	4 studies	51% ± 13%	Explore
OFF-bipolar cell	4 studies	67% ± 28%	Explore
ON-bipolar cell	4 studies	59% ± 29%	Explore
brush cell	4 studies	51% ± 11%	Explore
retinal pigment epithelial cell	4 studies	54% ± 29%	Explore
adventitial cell	4 studies	69% ± 16%	Explore
mucus secreting cell	4 studies	35% ± 9%	Explore
Mueller cell	4 studies	50% ± 20%	Explore
germinal center B cell	4 studies	49% ± 17%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	64% ± 11%	Explore
megakaryocyte-erythroid progenitor cell	4 studies	70% ± 31%	Explore
group 3 innate lymphoid cell	4 studies	54% ± 13%	Explore
T-helper 17 cell	4 studies	54% ± 28%	Explore
duct epithelial cell	3 studies	47% ± 4%	Explore
pancreatic D cell	3 studies	90% ± 8%	Explore
podocyte	3 studies	65% ± 18%	Explore
neural crest cell	3 studies	84% ± 19%	Explore
retinal bipolar neuron	3 studies	68% ± 14%	Explore
GABAergic amacrine cell	3 studies	45% ± 10%	Explore
glycinergic amacrine cell	3 studies	37% ± 14%	Explore
thymocyte	3 studies	61% ± 26%	Explore
extravillous trophoblast	3 studies	75% ± 10%	Explore
placental villous trophoblast	3 studies	70% ± 14%	Explore
common myeloid progenitor	3 studies	58% ± 30%	Explore
lymphocyte	3 studies	79% ± 11%	Explore
neuroendocrine cell	3 studies	51% ± 7%	Explore
Schwann cell	3 studies	67% ± 34%	Explore
serous secreting cell	3 studies	31% ± 3%	Explore
tissue-resident macrophage	3 studies	55% ± 20%	Explore
intraepithelial lymphocyte	3 studies	56% ± 13%	Explore
rod bipolar cell	3 studies	51% ± 18%	Explore
acinar cell	3 studies	40% ± 19%	Explore
muscle cell	3 studies	58% ± 14%	Explore
exhausted T cell	3 studies	48% ± 19%	Explore
IgA plasma cell	3 studies	26% ± 4%	Explore
IgG plasma cell	3 studies	24% ± 7%	Explore
myoepithelial cell	3 studies	80% ± 10%	Explore
luminal cell of prostate epithelium	3 studies	26% ± 7%	Explore
pancreatic ductal cell	3 studies	80% ± 1%	Explore
neural progenitor cell	3 studies	45% ± 33%	Explore
hepatocyte	3 studies	33% ± 16%	Explore
keratinocyte	3 studies	50% ± 6%	Explore
T-helper 1 cell	3 studies	64% ± 14%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	37% ± 14%	Explore
double negative thymocyte	3 studies	62% ± 22%	Explore
double-positive, alpha-beta thymocyte	3 studies	67% ± 14%	Explore
progenitor cell of mammary luminal epithelium	3 studies	73% ± 1%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	20 studies	41% ± 17%	Explore
lung	18 studies	52% ± 15%	Explore
brain	18 studies	47% ± 18%	Explore
intestine	14 studies	42% ± 18%	Explore
eye	11 studies	57% ± 22%	Explore
kidney	9 studies	45% ± 20%	Explore
liver	8 studies	48% ± 22%	Explore
bone marrow	7 studies	47% ± 20%	Explore
lymph node	7 studies	58% ± 17%	Explore
uterus	6 studies	61% ± 10%	Explore
pancreas	5 studies	68% ± 24%	Explore
placenta	4 studies	64% ± 15%	Explore
prostate	4 studies	52% ± 16%	Explore
breast	4 studies	69% ± 8%	Explore
ovary	3 studies	58% ± 1%	Explore
heart	3 studies	35% ± 13%	Explore
adipose	3 studies	37% ± 10%	Explore
adrenal gland	3 studies	51% ± 14%	Explore
esophagus	3 studies	46% ± 7%	Explore
skin	3 studies	53% ± 9%	Explore
thymus	3 studies	69% ± 29%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	6735.65	1441 / 1445	99%	164.62	182 / 183
intestine	100%	5618.54	965 / 966	99%	159.56	520 / 527
brain	99%	9882.72	2609 / 2642	99%	172.13	701 / 705
lung	99%	6747.45	573 / 578	99%	124.49	1141 / 1155
breast	100%	5242.80	457 / 459	97%	115.66	1089 / 1118
uterus	99%	5381.44	169 / 170	96%	138.02	442 / 459
ovary	95%	3837.04	171 / 180	100%	275.07	430 / 430
skin	96%	9635.81	1740 / 1809	99%	160.70	465 / 472
bladder	95%	5674.57	20 / 21	95%	127.05	479 / 504
stomach	91%	3788.88	325 / 359	100%	186.75	285 / 286
thymus	97%	3585.87	635 / 653	90%	60.98	546 / 605
kidney	91%	3267.58	81 / 89	90%	71.87	815 / 901
adrenal gland	96%	3702.30	248 / 258	83%	65.99	191 / 230
prostate	90%	2919.27	220 / 245	89%	40.52	445 / 502
pancreas	41%	893.53	136 / 328	97%	75.28	172 / 178
tonsil	0%	0	0 / 0	100%	158.64	45 / 45
ureter	0%	0	0 / 0	100%	31.31	1 / 1
adipose	100%	6134.68	1202 / 1204	0%	0	0 / 0
blood vessel	99%	7889.62	1326 / 1335	0%	0	0 / 0
spleen	99%	5014.55	238 / 241	0%	0	0 / 0
eye	0%	0	0 / 0	98%	60.59	78 / 80
liver	34%	997.40	76 / 226	60%	32.74	245 / 406
heart	93%	4212.17	802 / 861	0%	0	0 / 0
lymph node	0%	0	0 / 0	93%	150.90	27 / 29
peripheral blood	90%	7540.84	835 / 929	0%	0	0 / 0
muscle	62%	1690.30	501 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0007017	Biological process	microtubule-based process
GO_0051301	Biological process	cell division
GO_0000278	Biological process	mitotic cell cycle
GO_0030705	Biological process	cytoskeleton-dependent intracellular transport
GO_0071353	Biological process	cellular response to interleukin-4
GO_0000226	Biological process	microtubule cytoskeleton organization
GO_0015630	Cellular component	microtubule cytoskeleton
GO_0005881	Cellular component	cytoplasmic microtubule
GO_0005874	Cellular component	microtubule
GO_0005737	Cellular component	cytoplasm
GO_0005525	Molecular function	GTP binding
GO_0005200	Molecular function	structural constituent of cytoskeleton
GO_0005515	Molecular function	protein binding
GO_0031625	Molecular function	ubiquitin protein ligase binding
GO_0005198	Molecular function	structural molecule activity
GO_0003725	Molecular function	double-stranded RNA binding
GO_0003924	Molecular function	GTPase activity

IV. Literature review

[source]

Gene name	TUBA1B
Protein name	Tubulin alpha 1b Tubulin alpha-1C chain Tubulin alpha-1B chain (EC 3.6.5.-) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) (Tubulin alpha-ubiquitous chain) [Cleaved into: Detyrosinated tubulin alpha-1B chain]
Synonyms
Description	FUNCTION: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers . Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms . Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin . .
Accessions	ENST00000552984.1 F8VVB9 F8VRK0 F8VX09 ENST00000550367.1 ENST00000549870.5 ENST00000547765.5 P68363 F8VU66 ENST00000336023.9 [P68363-1] ENST00000547476.5 F8VWV9

TUBA1B report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review