Name | Number of supported studies | Average coverage | |
---|---|---|---|
lung | 19 studies | 42% ± 16% | |
peripheral blood | 16 studies | 29% ± 12% | |
intestine | 9 studies | 39% ± 17% | |
kidney | 8 studies | 28% ± 12% | |
brain | 7 studies | 35% ± 6% | |
placenta | 5 studies | 50% ± 27% | |
uterus | 5 studies | 62% ± 16% | |
lymph node | 5 studies | 27% ± 6% | |
breast | 5 studies | 45% ± 16% | |
pancreas | 4 studies | 41% ± 18% | |
bone marrow | 4 studies | 43% ± 22% | |
heart | 4 studies | 26% ± 10% | |
esophagus | 4 studies | 41% ± 21% | |
prostate | 4 studies | 60% ± 24% | |
eye | 3 studies | 28% ± 8% | |
adrenal gland | 3 studies | 20% ± 6% | |
skin | 3 studies | 38% ± 7% | |
liver | 3 studies | 25% ± 3% | |
adipose | 3 studies | 35% ± 15% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 28603.18 | 1445 / 1445 | 100% | 177.16 | 183 / 183 |
ovary | 100% | 33956.73 | 180 / 180 | 100% | 293.42 | 430 / 430 |
breast | 100% | 33992.82 | 459 / 459 | 100% | 199.77 | 1116 / 1118 |
intestine | 100% | 23953.87 | 965 / 966 | 100% | 151.89 | 526 / 527 |
lung | 100% | 44967.29 | 577 / 578 | 100% | 143.90 | 1152 / 1155 |
uterus | 100% | 47152.93 | 170 / 170 | 100% | 198.93 | 457 / 459 |
skin | 100% | 51742.73 | 1808 / 1809 | 99% | 109.34 | 467 / 472 |
bladder | 100% | 32581.14 | 21 / 21 | 99% | 140.64 | 498 / 504 |
prostate | 100% | 26007.81 | 244 / 245 | 98% | 91.61 | 492 / 502 |
stomach | 91% | 17551.64 | 328 / 359 | 100% | 153.42 | 286 / 286 |
thymus | 99% | 15694.25 | 644 / 653 | 90% | 44.85 | 545 / 605 |
adrenal gland | 97% | 12711.82 | 249 / 258 | 87% | 58.45 | 201 / 230 |
kidney | 97% | 15999.30 | 86 / 89 | 80% | 67.26 | 725 / 901 |
brain | 75% | 8999.79 | 1990 / 2642 | 87% | 58.79 | 612 / 705 |
pancreas | 38% | 3561.87 | 126 / 328 | 97% | 188.92 | 173 / 178 |
adipose | 100% | 38718.62 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 58090.71 | 1335 / 1335 | 0% | 0 | 0 / 0 |
spleen | 100% | 29338.78 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 155.75 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 96.97 | 1 / 1 |
lymph node | 0% | 0 | 0 / 0 | 97% | 95.39 | 28 / 29 |
peripheral blood | 93% | 17613.18 | 864 / 929 | 0% | 0 | 0 / 0 |
heart | 82% | 12063.13 | 705 / 861 | 0% | 0 | 0 / 0 |
liver | 15% | 1406.57 | 33 / 226 | 48% | 36.72 | 194 / 406 |
eye | 0% | 0 | 0 / 0 | 46% | 18.10 | 37 / 80 |
muscle | 14% | 1137.14 | 110 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0001649 | Biological process | osteoblast differentiation |
GO_0006936 | Biological process | muscle contraction |
GO_0007015 | Biological process | actin filament organization |
GO_0030220 | Biological process | platelet formation |
GO_0005862 | Cellular component | muscle thin filament tropomyosin |
GO_0005856 | Cellular component | cytoskeleton |
GO_0016020 | Cellular component | membrane |
GO_0070062 | Cellular component | extracellular exosome |
GO_0002102 | Cellular component | podosome |
GO_0005884 | Cellular component | actin filament |
GO_0005925 | Cellular component | focal adhesion |
GO_0001725 | Cellular component | stress fiber |
GO_0030863 | Cellular component | cortical cytoskeleton |
GO_0005829 | Cellular component | cytosol |
GO_0042803 | Molecular function | protein homodimerization activity |
GO_0008307 | Molecular function | structural constituent of muscle |
GO_0051015 | Molecular function | actin filament binding |
GO_0042802 | Molecular function | identical protein binding |
GO_0046982 | Molecular function | protein heterodimerization activity |
GO_0005509 | Molecular function | calcium ion binding |
GO_0005515 | Molecular function | protein binding |
Gene name | TPM4 |
Protein name | Tropomyosin 4 Tropomyosin alpha-4 chain (TM30p1) (Tropomyosin-4) |
Synonyms | hCG_1999582 |
Description | FUNCTION: Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments (By similarity). Binds calcium . . |
Accessions | A0A5F9UN72 ENST00000643494.1 ENST00000586499.6 A0A2R8YHD2 ENST00000647037.1 ENST00000300933.9 ENST00000670382.1 ENST00000645471.1 ENST00000344824.11 K7ENT6 A0A2R8Y5V9 A0A590UK79 ENST00000589897.1 ENST00000642221.1 ENST00000653979.1 K7ERG3 ENST00000642789.1 A0A2R8YGX3 ENST00000643579.2 [P67936-1] A0A5F9UKJ4 ENST00000588032.6 K7EPB9 ENST00000659595.1 A0A590UJB9 A0A2R8YEU4 ENST00000586833.7 ENST00000646974.2 [P67936-2] P67936 K7ELP0 ENST00000646575.2 A0A590UKD0 A0A2R8YE05 ENST00000647464.2 |