TPM4 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0001649Biological processosteoblast differentiation
GO_0006936Biological processmuscle contraction
GO_0007015Biological processactin filament organization
GO_0030220Biological processplatelet formation
GO_0005862Cellular componentmuscle thin filament tropomyosin
GO_0005856Cellular componentcytoskeleton
GO_0016020Cellular componentmembrane
GO_0070062Cellular componentextracellular exosome
GO_0002102Cellular componentpodosome
GO_0005884Cellular componentactin filament
GO_0005925Cellular componentfocal adhesion
GO_0001725Cellular componentstress fiber
GO_0030863Cellular componentcortical cytoskeleton
GO_0005829Cellular componentcytosol
GO_0042803Molecular functionprotein homodimerization activity
GO_0008307Molecular functionstructural constituent of muscle
GO_0051015Molecular functionactin filament binding
GO_0042802Molecular functionidentical protein binding
GO_0046982Molecular functionprotein heterodimerization activity
GO_0005509Molecular functioncalcium ion binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameTPM4
Protein nameTropomyosin 4
Tropomyosin alpha-4 chain (TM30p1) (Tropomyosin-4)
SynonymshCG_1999582
DescriptionFUNCTION: Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments (By similarity). Binds calcium . .

AccessionsA0A5F9UN72
ENST00000643494.1
ENST00000586499.6
A0A2R8YHD2
ENST00000647037.1
ENST00000300933.9
ENST00000670382.1
ENST00000645471.1
ENST00000344824.11
K7ENT6
A0A2R8Y5V9
A0A590UK79
ENST00000589897.1
ENST00000642221.1
ENST00000653979.1
K7ERG3
ENST00000642789.1
A0A2R8YGX3
ENST00000643579.2 [P67936-1]
A0A5F9UKJ4
ENST00000588032.6
K7EPB9
ENST00000659595.1
A0A590UJB9
A0A2R8YEU4
ENST00000586833.7
ENST00000646974.2 [P67936-2]
P67936
K7ELP0
ENST00000646575.2
A0A590UKD0
A0A2R8YE05
ENST00000647464.2