TCEA1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
B cell	38 studies	46% ± 14%	Explore
natural killer cell	33 studies	34% ± 13%	Explore
fibroblast	31 studies	29% ± 11%	Explore
CD4-positive, alpha-beta T cell	29 studies	34% ± 11%	Explore
CD8-positive, alpha-beta T cell	29 studies	35% ± 12%	Explore
endothelial cell	27 studies	26% ± 10%	Explore
conventional dendritic cell	27 studies	30% ± 14%	Explore
T cell	26 studies	33% ± 12%	Explore
regulatory T cell	25 studies	39% ± 10%	Explore
pericyte	24 studies	30% ± 9%	Explore
smooth muscle cell	24 studies	30% ± 10%	Explore
macrophage	23 studies	27% ± 8%	Explore
memory B cell	20 studies	53% ± 11%	Explore
naive B cell	20 studies	39% ± 11%	Explore
non-classical monocyte	20 studies	29% ± 11%	Explore
plasmacytoid dendritic cell	20 studies	42% ± 15%	Explore
classical monocyte	20 studies	30% ± 9%	Explore
plasma cell	18 studies	38% ± 16%	Explore
mature NK T cell	18 studies	31% ± 9%	Explore
epithelial cell	17 studies	36% ± 19%	Explore
gamma-delta T cell	17 studies	38% ± 13%	Explore
monocyte	15 studies	26% ± 8%	Explore
mast cell	14 studies	30% ± 7%	Explore
CD16-negative, CD56-bright natural killer cell, human	14 studies	34% ± 11%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	14 studies	38% ± 10%	Explore
basal cell	14 studies	36% ± 16%	Explore
ciliated cell	14 studies	41% ± 17%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	14 studies	34% ± 8%	Explore
connective tissue cell	14 studies	31% ± 9%	Explore
myofibroblast cell	14 studies	32% ± 11%	Explore
CD16-positive, CD56-dim natural killer cell, human	13 studies	39% ± 9%	Explore
endothelial cell of lymphatic vessel	12 studies	29% ± 6%	Explore
plasmablast	12 studies	50% ± 23%	Explore
CD8-positive, alpha-beta memory T cell	12 studies	39% ± 12%	Explore
mucosal invariant T cell	12 studies	35% ± 10%	Explore
CD4-positive, alpha-beta memory T cell	11 studies	36% ± 9%	Explore
dendritic cell	10 studies	44% ± 23%	Explore
capillary endothelial cell	10 studies	24% ± 8%	Explore
endothelial cell of artery	10 studies	23% ± 4%	Explore
type I pneumocyte	9 studies	26% ± 12%	Explore
secretory cell	9 studies	34% ± 17%	Explore
effector memory CD8-positive, alpha-beta T cell	9 studies	38% ± 9%	Explore
abnormal cell	9 studies	44% ± 13%	Explore
vein endothelial cell	9 studies	24% ± 8%	Explore
astrocyte	9 studies	32% ± 13%	Explore
type II pneumocyte	8 studies	35% ± 12%	Explore
endothelial cell of vascular tree	8 studies	25% ± 6%	Explore
club cell	7 studies	31% ± 11%	Explore
platelet	7 studies	22% ± 3%	Explore
goblet cell	7 studies	28% ± 12%	Explore
hematopoietic stem cell	7 studies	40% ± 13%	Explore
myeloid cell	7 studies	33% ± 11%	Explore
T follicular helper cell	7 studies	34% ± 6%	Explore
oligodendrocyte precursor cell	7 studies	25% ± 7%	Explore
alveolar macrophage	6 studies	18% ± 3%	Explore
effector CD8-positive, alpha-beta T cell	6 studies	47% ± 14%	Explore
leukocyte	6 studies	31% ± 11%	Explore
mononuclear phagocyte	6 studies	24% ± 10%	Explore
epithelial cell of proximal tubule	6 studies	23% ± 5%	Explore
progenitor cell	6 studies	28% ± 13%	Explore
IgA plasma cell	6 studies	27% ± 9%	Explore
precursor B cell	6 studies	45% ± 13%	Explore
neuron	6 studies	34% ± 15%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	39% ± 10%	Explore
erythrocyte	6 studies	41% ± 25%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	5 studies	33% ± 12%	Explore
hematopoietic precursor cell	5 studies	42% ± 14%	Explore
exhausted T cell	5 studies	42% ± 6%	Explore
respiratory goblet cell	5 studies	24% ± 8%	Explore
effector CD4-positive, alpha-beta T cell	5 studies	43% ± 14%	Explore
IgG plasma cell	5 studies	27% ± 9%	Explore
pro-B cell	5 studies	43% ± 8%	Explore
brush cell	5 studies	32% ± 14%	Explore
immature B cell	5 studies	48% ± 9%	Explore
mesothelial cell	5 studies	30% ± 15%	Explore
innate lymphoid cell	5 studies	32% ± 6%	Explore
glutamatergic neuron	5 studies	31% ± 13%	Explore
oligodendrocyte	5 studies	21% ± 4%	Explore
CD4-positive helper T cell	4 studies	25% ± 7%	Explore
central memory CD8-positive, alpha-beta T cell	4 studies	34% ± 14%	Explore
pancreatic A cell	4 studies	48% ± 12%	Explore
type B pancreatic cell	4 studies	52% ± 18%	Explore
kidney loop of Henle epithelial cell	4 studies	28% ± 5%	Explore
kidney distal convoluted tubule epithelial cell	4 studies	31% ± 7%	Explore
lymphocyte	4 studies	36% ± 13%	Explore
megakaryocyte	4 studies	30% ± 6%	Explore
amacrine cell	4 studies	31% ± 11%	Explore
retina horizontal cell	4 studies	24% ± 7%	Explore
retinal cone cell	4 studies	40% ± 15%	Explore
retinal rod cell	4 studies	28% ± 10%	Explore
adventitial cell	4 studies	21% ± 6%	Explore
germinal center B cell	4 studies	62% ± 16%	Explore
intermediate monocyte	4 studies	43% ± 13%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	35% ± 6%	Explore
enteroendocrine cell	4 studies	30% ± 14%	Explore
T-helper 17 cell	4 studies	34% ± 10%	Explore
double negative thymocyte	4 studies	50% ± 12%	Explore
microglial cell	4 studies	20% ± 4%	Explore
ionocyte	3 studies	35% ± 14%	Explore
pancreatic D cell	3 studies	47% ± 20%	Explore
glomerular endothelial cell	3 studies	20% ± 3%	Explore
renal alpha-intercalated cell	3 studies	26% ± 5%	Explore
neural crest cell	3 studies	27% ± 0%	Explore
retinal bipolar neuron	3 studies	31% ± 10%	Explore
erythroblast	3 studies	66% ± 12%	Explore
neuroendocrine cell	3 studies	43% ± 14%	Explore
serous secreting cell	3 studies	28% ± 8%	Explore
Mueller cell	3 studies	34% ± 4%	Explore
rod bipolar cell	3 studies	28% ± 8%	Explore
myoepithelial cell	3 studies	28% ± 8%	Explore
muscle cell	3 studies	33% ± 11%	Explore
GABAergic neuron	3 studies	35% ± 2%	Explore
pancreatic ductal cell	3 studies	51% ± 17%	Explore
granulocyte	3 studies	31% ± 3%	Explore
intestinal crypt stem cell	3 studies	24% ± 5%	Explore
group 3 innate lymphoid cell	3 studies	44% ± 14%	Explore
transit amplifying cell	3 studies	29% ± 13%	Explore
keratinocyte	3 studies	24% ± 4%	Explore
T-helper 1 cell	3 studies	39% ± 8%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	43% ± 8%	Explore
hepatocyte	3 studies	41% ± 23%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	18 studies	37% ± 10%	Explore
lung	16 studies	33% ± 15%	Explore
intestine	9 studies	26% ± 10%	Explore
kidney	7 studies	26% ± 8%	Explore
eye	7 studies	27% ± 10%	Explore
brain	7 studies	28% ± 8%	Explore
lymph node	5 studies	38% ± 4%	Explore
liver	5 studies	36% ± 22%	Explore
pancreas	4 studies	45% ± 17%	Explore
bone marrow	4 studies	30% ± 7%	Explore
uterus	4 studies	37% ± 14%	Explore
breast	4 studies	25% ± 5%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	3602.72	1445 / 1445	100%	71.97	183 / 183
lung	100%	3098.39	578 / 578	100%	67.06	1155 / 1155
ovary	100%	3366.26	180 / 180	100%	56.04	430 / 430
prostate	100%	3192.21	245 / 245	100%	58.99	502 / 502
brain	100%	2793.87	2641 / 2642	100%	66.79	705 / 705
breast	100%	3635.00	459 / 459	100%	78.18	1117 / 1118
uterus	100%	3579.30	170 / 170	100%	57.27	458 / 459
pancreas	100%	2277.71	328 / 328	99%	41.90	177 / 178
liver	100%	2441.65	226 / 226	99%	38.06	403 / 406
thymus	100%	3459.46	653 / 653	99%	54.03	600 / 605
bladder	100%	3901.24	21 / 21	98%	51.80	496 / 504
stomach	100%	2941.69	359 / 359	98%	51.95	280 / 286
kidney	100%	2530.48	89 / 89	98%	41.37	881 / 901
adrenal gland	100%	3170.40	258 / 258	97%	33.61	224 / 230
intestine	100%	3718.27	966 / 966	97%	47.92	511 / 527
skin	100%	4161.81	1807 / 1809	97%	50.46	457 / 472
blood vessel	100%	4649.87	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	56.20	29 / 29
spleen	100%	2562.75	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	51.71	45 / 45
ureter	0%	0	0 / 0	100%	19.58	1 / 1
adipose	100%	3704.75	1203 / 1204	0%	0	0 / 0
muscle	100%	1927.88	800 / 803	0%	0	0 / 0
heart	95%	1534.13	815 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	93%	38.84	74 / 80
peripheral blood	83%	3145.35	769 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0006366	Biological process	transcription by RNA polymerase II
GO_0006351	Biological process	DNA-templated transcription
GO_0006368	Biological process	transcription elongation by RNA polymerase II
GO_0045944	Biological process	positive regulation of transcription by RNA polymerase II
GO_0005730	Cellular component	nucleolus
GO_0005669	Cellular component	transcription factor TFIID complex
GO_0005654	Cellular component	nucleoplasm
GO_0005634	Cellular component	nucleus
GO_0003677	Molecular function	DNA binding
GO_0005515	Molecular function	protein binding
GO_0008270	Molecular function	zinc ion binding

IV. Literature review

[source]

Gene name	TCEA1
Protein name	Transcription elongation factor A protein 1 (Transcription elongation factor S-II protein 1) (Transcription elongation factor TFIIS.o) Transcription elongation factor A1 Transcription elongation factor A1 (cDNA FLJ51251, moderately similar to Transcription elongation factor A protein 1)
Synonyms	GTF2S TFIIS
Description	FUNCTION: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
Accessions	E5RK46 ENST00000519704.1 ENST00000521604.7 [P23193-1] E5RIS7 ENST00000522635.5 ENST00000396401.7 [P23193-2] P23193 ENST00000520534.5 E5RFI1 E5RJ93 ENST00000518310.5 ENST00000518784.5 B7Z4S1

TCEA1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review