RTRAF | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
B cell	33 studies	36% ± 13%	Explore
natural killer cell	33 studies	31% ± 11%	Explore
fibroblast	32 studies	38% ± 14%	Explore
CD8-positive, alpha-beta T cell	30 studies	39% ± 17%	Explore
endothelial cell	28 studies	40% ± 16%	Explore
CD4-positive, alpha-beta T cell	28 studies	41% ± 16%	Explore
conventional dendritic cell	26 studies	44% ± 15%	Explore
T cell	25 studies	39% ± 15%	Explore
pericyte	24 studies	36% ± 12%	Explore
macrophage	23 studies	31% ± 10%	Explore
regulatory T cell	23 studies	43% ± 13%	Explore
smooth muscle cell	22 studies	39% ± 15%	Explore
classical monocyte	21 studies	35% ± 13%	Explore
non-classical monocyte	20 studies	38% ± 15%	Explore
plasmacytoid dendritic cell	20 studies	43% ± 14%	Explore
epithelial cell	19 studies	42% ± 22%	Explore
memory B cell	18 studies	34% ± 10%	Explore
monocyte	17 studies	32% ± 9%	Explore
basal cell	17 studies	41% ± 17%	Explore
naive B cell	17 studies	31% ± 8%	Explore
dendritic cell	16 studies	44% ± 24%	Explore
mast cell	15 studies	36% ± 15%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	15 studies	36% ± 11%	Explore
mature NK T cell	15 studies	33% ± 9%	Explore
connective tissue cell	15 studies	45% ± 15%	Explore
gamma-delta T cell	15 studies	36% ± 16%	Explore
endothelial cell of lymphatic vessel	13 studies	44% ± 12%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	13 studies	40% ± 13%	Explore
plasma cell	13 studies	43% ± 12%	Explore
CD16-positive, CD56-dim natural killer cell, human	13 studies	31% ± 8%	Explore
ciliated cell	13 studies	43% ± 18%	Explore
myofibroblast cell	12 studies	43% ± 15%	Explore
CD8-positive, alpha-beta memory T cell	11 studies	38% ± 17%	Explore
CD16-negative, CD56-bright natural killer cell, human	11 studies	36% ± 9%	Explore
capillary endothelial cell	11 studies	34% ± 14%	Explore
mucosal invariant T cell	11 studies	33% ± 8%	Explore
endothelial cell of vascular tree	11 studies	37% ± 8%	Explore
plasmablast	10 studies	50% ± 23%	Explore
secretory cell	10 studies	34% ± 17%	Explore
endothelial cell of artery	10 studies	36% ± 16%	Explore
vein endothelial cell	10 studies	37% ± 14%	Explore
CD4-positive, alpha-beta memory T cell	9 studies	42% ± 15%	Explore
progenitor cell	9 studies	53% ± 13%	Explore
abnormal cell	9 studies	34% ± 12%	Explore
goblet cell	9 studies	35% ± 15%	Explore
leukocyte	8 studies	36% ± 13%	Explore
effector memory CD8-positive, alpha-beta T cell	8 studies	37% ± 15%	Explore
hematopoietic stem cell	8 studies	54% ± 19%	Explore
myeloid cell	8 studies	33% ± 14%	Explore
club cell	7 studies	34% ± 10%	Explore
effector CD8-positive, alpha-beta T cell	7 studies	45% ± 19%	Explore
epithelial cell of proximal tubule	7 studies	29% ± 10%	Explore
mesothelial cell	7 studies	55% ± 21%	Explore
T follicular helper cell	7 studies	40% ± 7%	Explore
neuron	7 studies	45% ± 21%	Explore
type I pneumocyte	6 studies	32% ± 16%	Explore
kidney loop of Henle epithelial cell	6 studies	26% ± 6%	Explore
enterocyte	6 studies	29% ± 10%	Explore
precursor B cell	6 studies	46% ± 14%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	45% ± 19%	Explore
CD4-positive helper T cell	5 studies	26% ± 9%	Explore
hematopoietic precursor cell	5 studies	58% ± 31%	Explore
mononuclear phagocyte	5 studies	43% ± 17%	Explore
renal alpha-intercalated cell	5 studies	41% ± 10%	Explore
enteroendocrine cell	5 studies	49% ± 20%	Explore
intestinal crypt stem cell	5 studies	39% ± 11%	Explore
transit amplifying cell	5 studies	29% ± 12%	Explore
pro-B cell	5 studies	48% ± 10%	Explore
innate lymphoid cell	5 studies	32% ± 2%	Explore
immature B cell	5 studies	46% ± 22%	Explore
type II pneumocyte	5 studies	42% ± 16%	Explore
erythrocyte	5 studies	42% ± 21%	Explore
effector CD4-positive, alpha-beta T cell	5 studies	55% ± 21%	Explore
granulocyte	5 studies	34% ± 14%	Explore
alveolar macrophage	4 studies	28% ± 9%	Explore
exhausted T cell	4 studies	55% ± 13%	Explore
retinal ganglion cell	4 studies	50% ± 28%	Explore
erythroblast	4 studies	49% ± 19%	Explore
microglial cell	4 studies	27% ± 12%	Explore
germinal center B cell	4 studies	44% ± 16%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	47% ± 8%	Explore
oligodendrocyte	4 studies	21% ± 4%	Explore
double negative thymocyte	4 studies	51% ± 23%	Explore
oligodendrocyte precursor cell	4 studies	31% ± 21%	Explore
deuterosomal cell	3 studies	24% ± 5%	Explore
duct epithelial cell	3 studies	27% ± 4%	Explore
precursor cell	3 studies	61% ± 20%	Explore
platelet	3 studies	18% ± 2%	Explore
pancreatic A cell	3 studies	50% ± 14%	Explore
type B pancreatic cell	3 studies	43% ± 17%	Explore
glomerular endothelial cell	3 studies	23% ± 3%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	58% ± 22%	Explore
neural crest cell	3 studies	66% ± 14%	Explore
extravillous trophoblast	3 studies	46% ± 12%	Explore
placental villous trophoblast	3 studies	56% ± 21%	Explore
lymphocyte	3 studies	48% ± 6%	Explore
megakaryocyte	3 studies	23% ± 3%	Explore
retinal cone cell	3 studies	37% ± 12%	Explore
retinal rod cell	3 studies	30% ± 11%	Explore
adventitial cell	3 studies	29% ± 4%	Explore
Mueller cell	3 studies	27% ± 6%	Explore
acinar cell	3 studies	29% ± 13%	Explore
intermediate monocyte	3 studies	49% ± 24%	Explore
myoepithelial cell	3 studies	43% ± 12%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	56% ± 30%	Explore
glial cell	3 studies	43% ± 25%	Explore
group 3 innate lymphoid cell	3 studies	44% ± 16%	Explore
keratinocyte	3 studies	35% ± 7%	Explore
T-helper 17 cell	3 studies	43% ± 27%	Explore
glutamatergic neuron	3 studies	23% ± 9%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	32% ± 8%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	38% ± 11%	Explore
central memory CD8-positive, alpha-beta T cell	3 studies	33% ± 12%	Explore
progenitor cell of mammary luminal epithelium	3 studies	46% ± 8%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	17 studies	39% ± 12%	Explore
lung	13 studies	41% ± 16%	Explore
intestine	10 studies	36% ± 16%	Explore
kidney	8 studies	34% ± 9%	Explore
eye	8 studies	25% ± 11%	Explore
brain	6 studies	20% ± 3%	Explore
placenta	5 studies	35% ± 18%	Explore
bone marrow	5 studies	27% ± 8%	Explore
liver	5 studies	34% ± 24%	Explore
pancreas	4 studies	41% ± 18%	Explore
uterus	4 studies	42% ± 16%	Explore
prostate	4 studies	24% ± 9%	Explore
breast	4 studies	38% ± 4%	Explore
thymus	3 studies	62% ± 30%	Explore
lymph node	3 studies	36% ± 3%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
bladder	100%	5288.24	21 / 21	100%	48.23	504 / 504
breast	100%	5966.08	459 / 459	100%	56.56	1118 / 1118
esophagus	100%	5787.80	1445 / 1445	100%	37.34	183 / 183
kidney	100%	4236.74	89 / 89	100%	30.17	901 / 901
ovary	100%	5875.81	180 / 180	100%	37.66	430 / 430
pancreas	100%	3655.38	328 / 328	100%	41.36	178 / 178
prostate	100%	4849.85	245 / 245	100%	52.09	502 / 502
skin	100%	5991.14	1809 / 1809	100%	46.25	472 / 472
stomach	100%	5342.10	359 / 359	100%	38.58	286 / 286
thymus	100%	5706.60	653 / 653	100%	55.62	605 / 605
uterus	100%	4837.89	170 / 170	100%	53.76	459 / 459
intestine	100%	5736.38	966 / 966	100%	45.51	526 / 527
lung	100%	4394.80	576 / 578	100%	42.84	1155 / 1155
adrenal gland	100%	5823.07	258 / 258	100%	35.92	229 / 230
liver	100%	2363.97	225 / 226	100%	26.15	406 / 406
brain	99%	2994.12	2622 / 2642	100%	34.59	705 / 705
adipose	100%	6015.13	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	73.71	29 / 29
muscle	100%	5800.49	803 / 803	0%	0	0 / 0
spleen	100%	3994.76	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	44.86	45 / 45
ureter	0%	0	0 / 0	100%	35.96	1 / 1
blood vessel	100%	5492.43	1334 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	99%	45.43	79 / 80
heart	99%	5797.93	849 / 861	0%	0	0 / 0
peripheral blood	84%	3328.91	779 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0050658	Biological process	RNA transport
GO_0006469	Biological process	negative regulation of protein kinase activity
GO_0006388	Biological process	tRNA splicing, via endonucleolytic cleavage and ligation
GO_0045944	Biological process	positive regulation of transcription by RNA polymerase II
GO_0005813	Cellular component	centrosome
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0072669	Cellular component	tRNA-splicing ligase complex
GO_0072686	Cellular component	mitotic spindle
GO_0048471	Cellular component	perinuclear region of cytoplasm
GO_0005737	Cellular component	cytoplasm
GO_0005634	Cellular component	nucleus
GO_0000993	Molecular function	RNA polymerase II complex binding
GO_0042802	Molecular function	identical protein binding
GO_0005515	Molecular function	protein binding
GO_0003723	Molecular function	RNA binding

IV. Literature review

[source]

Gene name	RTRAF
Protein name	RNA transcription, translation and transport factor protein (CLE7 homolog) (CLE) (hCLE) RNA transcription, translation and transport factor protein RNA transcription, translation and transport factor
Synonyms	CGI-99 hCG_22667 C14orf166
Description	FUNCTION: RNA-binding protein involved in modulation of mRNA transcription by Polymerase II . Component of the tRNA-splicing ligase complex and is required for tRNA ligation . May be required for RNA transport . .; FUNCTION: (Microbial infection) In case of infection by influenza virus A (IVA), is involved in viral replication . .
Accessions	Q9Y224 G3V4C6 ENST00000261700.8 G3V4E7 ENST00000557553.5 H0YJB9 Q549M8 ENST00000556760.5 ENST00000553362.1

RTRAF report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review