RAB2A report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0016236Biological processmacroautophagy
GO_0016192Biological processvesicle-mediated transport
GO_0007030Biological processGolgi organization
GO_0015031Biological processprotein transport
GO_0006888Biological processendoplasmic reticulum to Golgi vesicle-mediated transport
GO_0001669Cellular componentacrosomal vesicle
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0000421Cellular componentautophagosome membrane
GO_0070062Cellular componentextracellular exosome
GO_0005794Cellular componentGolgi apparatus
GO_0033116Cellular componentendoplasmic reticulum-Golgi intermediate compartment membrane
GO_0000139Cellular componentGolgi membrane
GO_0005829Cellular componentcytosol
GO_0042470Cellular componentmelanosome
GO_0005765Cellular componentlysosomal membrane
GO_0005634Cellular componentnucleus
GO_0019003Molecular functionGDP binding
GO_0005525Molecular functionGTP binding
GO_0005515Molecular functionprotein binding
GO_0003924Molecular functionGTPase activity

IV. Literature review

[source]
Gene nameRAB2A
Protein namesmall monomeric GTPase (EC 3.6.5.2)
RAB2A, member RAS oncogene family
Ras-related protein Rab-2A (EC 3.6.5.2)
SynonymsRAB2
DescriptionFUNCTION: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between active GTP-bound and inactive GDP-bound states. In their active state, drive transport of vesicular carriers from donor organelles to acceptor organelles to regulate the membrane traffic that maintains organelle identity and morphology. Required for protein transport from the endoplasmic reticulum to the Golgi complex. Regulates the compacted morphology of the Golgi. .

FUNCTION: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between active GTP-bound and inactive GDP-bound states. In their active state, drive transport of vesicular carriers from donor organelles to acceptor organelles to regulate the membrane traffic that maintains organelle identity and morphology. Required for protein transport from the endoplasmic reticulum to the Golgi complex. Regulates the compacted morphology of the Golgi. .

FUNCTION: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between active GTP-bound and inactive GDP-bound states. In their active state, drive transport of vesicular carriers from donor organelles to acceptor organelles to regulate the membrane traffic that maintains organelle identity and morphology. Required for protein transport from the endoplasmic reticulum to the Golgi complex. Regulates the compacted morphology of the Golgi. .

AccessionsENST00000529579.5
A0A1D5RMT4
ENST00000531098.1
P61019
H7C125
ENST00000452437.1
E9PKL7
ENST00000466595.5
ENST00000262646.12 [P61019-1]
ENST00000531289.5 [P61019-2]
ENST00000534260.5
H0YDL5
H0YD31