PGAM1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	33 studies	37% ± 16%	Explore
CD8-positive, alpha-beta T cell	33 studies	40% ± 21%	Explore
fibroblast	32 studies	37% ± 17%	Explore
CD4-positive, alpha-beta T cell	30 studies	36% ± 21%	Explore
conventional dendritic cell	27 studies	42% ± 17%	Explore
B cell	26 studies	28% ± 11%	Explore
T cell	26 studies	39% ± 19%	Explore
endothelial cell	26 studies	35% ± 13%	Explore
pericyte	26 studies	40% ± 16%	Explore
macrophage	25 studies	33% ± 15%	Explore
classical monocyte	25 studies	46% ± 15%	Explore
smooth muscle cell	23 studies	36% ± 15%	Explore
non-classical monocyte	23 studies	52% ± 16%	Explore
regulatory T cell	23 studies	43% ± 16%	Explore
monocyte	18 studies	45% ± 11%	Explore
mature NK T cell	18 studies	32% ± 10%	Explore
memory B cell	18 studies	27% ± 12%	Explore
basal cell	18 studies	39% ± 19%	Explore
epithelial cell	17 studies	43% ± 19%	Explore
connective tissue cell	17 studies	40% ± 17%	Explore
plasmacytoid dendritic cell	16 studies	32% ± 13%	Explore
dendritic cell	15 studies	47% ± 23%	Explore
endothelial cell of lymphatic vessel	15 studies	38% ± 16%	Explore
CD16-positive, CD56-dim natural killer cell, human	15 studies	37% ± 11%	Explore
mast cell	14 studies	23% ± 5%	Explore
gamma-delta T cell	14 studies	42% ± 14%	Explore
naive B cell	13 studies	24% ± 8%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	13 studies	25% ± 5%	Explore
myofibroblast cell	13 studies	41% ± 16%	Explore
myeloid cell	13 studies	40% ± 18%	Explore
plasma cell	12 studies	44% ± 18%	Explore
CD8-positive, alpha-beta memory T cell	12 studies	34% ± 14%	Explore
capillary endothelial cell	12 studies	26% ± 12%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	11 studies	35% ± 11%	Explore
CD16-negative, CD56-bright natural killer cell, human	11 studies	34% ± 9%	Explore
vein endothelial cell	11 studies	27% ± 12%	Explore
plasmablast	10 studies	55% ± 22%	Explore
CD4-positive, alpha-beta memory T cell	10 studies	37% ± 18%	Explore
abnormal cell	10 studies	42% ± 20%	Explore
endothelial cell of artery	10 studies	24% ± 7%	Explore
endothelial cell of vascular tree	10 studies	26% ± 8%	Explore
mucosal invariant T cell	9 studies	39% ± 5%	Explore
effector memory CD8-positive, alpha-beta T cell	8 studies	37% ± 11%	Explore
T follicular helper cell	8 studies	37% ± 13%	Explore
ciliated cell	8 studies	34% ± 17%	Explore
type I pneumocyte	7 studies	25% ± 11%	Explore
effector CD8-positive, alpha-beta T cell	7 studies	50% ± 22%	Explore
progenitor cell	7 studies	44% ± 14%	Explore
retinal rod cell	7 studies	49% ± 20%	Explore
innate lymphoid cell	7 studies	26% ± 7%	Explore
hematopoietic precursor cell	6 studies	41% ± 20%	Explore
epithelial cell of proximal tubule	6 studies	37% ± 16%	Explore
neutrophil	6 studies	29% ± 11%	Explore
enterocyte	6 studies	32% ± 7%	Explore
mesothelial cell	6 studies	42% ± 18%	Explore
transit amplifying cell	6 studies	29% ± 8%	Explore
glutamatergic neuron	6 studies	30% ± 12%	Explore
amacrine cell	6 studies	58% ± 23%	Explore
retinal ganglion cell	6 studies	74% ± 27%	Explore
astrocyte	6 studies	39% ± 22%	Explore
retinal cone cell	6 studies	65% ± 24%	Explore
club cell	6 studies	27% ± 8%	Explore
neuron	6 studies	45% ± 24%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	5 studies	35% ± 12%	Explore
exhausted T cell	5 studies	55% ± 16%	Explore
secretory cell	5 studies	45% ± 17%	Explore
leukocyte	5 studies	34% ± 14%	Explore
mononuclear phagocyte	5 studies	32% ± 17%	Explore
kidney loop of Henle epithelial cell	5 studies	34% ± 6%	Explore
renal alpha-intercalated cell	5 studies	42% ± 11%	Explore
goblet cell	5 studies	25% ± 5%	Explore
retina horizontal cell	5 studies	69% ± 12%	Explore
precursor B cell	5 studies	41% ± 15%	Explore
pro-B cell	5 studies	38% ± 8%	Explore
effector memory CD4-positive, alpha-beta T cell	5 studies	39% ± 11%	Explore
erythrocyte	5 studies	30% ± 15%	Explore
alveolar macrophage	4 studies	27% ± 4%	Explore
CD4-positive, alpha-beta cytotoxic T cell	4 studies	41% ± 13%	Explore
ionocyte	4 studies	27% ± 9%	Explore
platelet	4 studies	21% ± 5%	Explore
pancreatic A cell	4 studies	62% ± 20%	Explore
type B pancreatic cell	4 studies	58% ± 28%	Explore
kidney distal convoluted tubule epithelial cell	4 studies	44% ± 8%	Explore
enteroendocrine cell	4 studies	40% ± 13%	Explore
OFF-bipolar cell	4 studies	70% ± 23%	Explore
ON-bipolar cell	4 studies	67% ± 23%	Explore
microglial cell	4 studies	31% ± 13%	Explore
erythroblast	4 studies	32% ± 9%	Explore
hematopoietic stem cell	4 studies	33% ± 6%	Explore
megakaryocyte	4 studies	35% ± 4%	Explore
immature B cell	4 studies	41% ± 13%	Explore
adventitial cell	4 studies	30% ± 4%	Explore
Mueller cell	4 studies	45% ± 15%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	60% ± 20%	Explore
intermediate monocyte	4 studies	56% ± 21%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	22% ± 5%	Explore
GABAergic neuron	4 studies	26% ± 11%	Explore
T-helper 17 cell	4 studies	46% ± 31%	Explore
CD4-positive helper T cell	3 studies	25% ± 8%	Explore
hillock cell	3 studies	46% ± 21%	Explore
precursor cell	3 studies	63% ± 4%	Explore
respiratory goblet cell	3 studies	33% ± 17%	Explore
pancreatic D cell	3 studies	59% ± 29%	Explore
glomerular endothelial cell	3 studies	21% ± 5%	Explore
intestinal crypt stem cell	3 studies	25% ± 6%	Explore
retinal bipolar neuron	3 studies	73% ± 17%	Explore
GABAergic amacrine cell	3 studies	64% ± 18%	Explore
glycinergic amacrine cell	3 studies	59% ± 21%	Explore
extravillous trophoblast	3 studies	52% ± 21%	Explore
placental villous trophoblast	3 studies	53% ± 26%	Explore
common myeloid progenitor	3 studies	38% ± 15%	Explore
lymphocyte	3 studies	45% ± 15%	Explore
neuroendocrine cell	3 studies	30% ± 11%	Explore
type II pneumocyte	3 studies	34% ± 17%	Explore
retinal pigment epithelial cell	3 studies	41% ± 27%	Explore
serous secreting cell	3 studies	28% ± 11%	Explore
intraepithelial lymphocyte	3 studies	36% ± 13%	Explore
rod bipolar cell	3 studies	67% ± 15%	Explore
germinal center B cell	3 studies	45% ± 14%	Explore
inflammatory macrophage	3 studies	25% ± 6%	Explore
muscle cell	3 studies	38% ± 21%	Explore
pancreatic ductal cell	3 studies	64% ± 21%	Explore
granulocyte	3 studies	26% ± 6%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	48% ± 22%	Explore
group 3 innate lymphoid cell	3 studies	44% ± 18%	Explore
keratinocyte	3 studies	30% ± 5%	Explore
interneuron	3 studies	30% ± 14%	Explore
T-helper 1 cell	3 studies	48% ± 12%	Explore
double negative thymocyte	3 studies	53% ± 13%	Explore
hepatocyte	3 studies	37% ± 16%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	18 studies	38% ± 11%	Explore
lung	17 studies	36% ± 16%	Explore
intestine	12 studies	27% ± 13%	Explore
eye	9 studies	50% ± 20%	Explore
brain	8 studies	26% ± 11%	Explore
kidney	7 studies	40% ± 9%	Explore
liver	7 studies	27% ± 9%	Explore
lymph node	6 studies	35% ± 10%	Explore
bone marrow	5 studies	26% ± 9%	Explore
uterus	5 studies	30% ± 12%	Explore
pancreas	4 studies	58% ± 24%	Explore
placenta	4 studies	40% ± 24%	Explore
breast	4 studies	25% ± 5%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	5735.15	1445 / 1445	100%	105.49	183 / 183
ovary	100%	2775.49	180 / 180	100%	81.83	430 / 430
brain	100%	4634.55	2636 / 2642	100%	87.30	703 / 705
stomach	99%	2317.15	357 / 359	100%	61.63	285 / 286
lung	99%	2711.35	574 / 578	100%	76.73	1150 / 1155
intestine	100%	3228.54	966 / 966	99%	57.26	521 / 527
skin	100%	6332.86	1808 / 1809	99%	65.95	465 / 472
breast	100%	2740.83	459 / 459	98%	53.94	1099 / 1118
uterus	100%	2812.25	170 / 170	98%	78.44	450 / 459
bladder	100%	3377.24	21 / 21	97%	65.32	490 / 504
kidney	100%	3117.56	89 / 89	97%	83.81	875 / 901
prostate	100%	2337.68	244 / 245	95%	33.61	478 / 502
thymus	100%	2014.66	650 / 653	95%	33.94	575 / 605
adrenal gland	100%	6036.91	258 / 258	90%	61.19	208 / 230
liver	95%	1973.67	215 / 226	89%	28.44	360 / 406
pancreas	73%	834.28	241 / 328	98%	44.47	174 / 178
adipose	100%	3081.86	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	90.05	29 / 29
spleen	100%	2891.97	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	97.26	45 / 45
ureter	0%	0	0 / 0	100%	21.82	1 / 1
blood vessel	100%	3618.25	1333 / 1335	0%	0	0 / 0
peripheral blood	99%	8599.10	922 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	96%	43.27	77 / 80
heart	93%	3365.29	802 / 861	0%	0	0 / 0
muscle	41%	418.38	330 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0061621	Biological process	canonical glycolysis
GO_0006094	Biological process	gluconeogenesis
GO_0034774	Cellular component	secretory granule lumen
GO_0070062	Cellular component	extracellular exosome
GO_1904813	Cellular component	ficolin-1-rich granule lumen
GO_0005829	Cellular component	cytosol
GO_0005576	Cellular component	extracellular region
GO_0016020	Cellular component	membrane
GO_0005737	Cellular component	cytoplasm
GO_0046538	Molecular function	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity
GO_0016787	Molecular function	hydrolase activity
GO_0019901	Molecular function	protein kinase binding
GO_0004619	Molecular function	phosphoglycerate mutase activity
GO_0005515	Molecular function	protein binding
GO_0004082	Molecular function	bisphosphoglycerate mutase activity

Gene name	PGAM1
Protein name	Phosphoglycerate mutase 1 (EC 5.4.2.11) (EC 5.4.2.4) (BPG-dependent PGAM 1) (Phosphoglycerate mutase isozyme B) (PGAM-B) Phosphoglycerate mutase (EC 5.4.2.11) (EC 5.4.2.4)
Synonyms	CDABP0006 hCG_25778 hCG_2015269 HEL-S-35 PGAMA
Description	FUNCTION: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglyceratea crucial step in glycolysis, by using 2,3-bisphosphoglycerate . Also catalyzes the interconversion of (2R)-2,3-bisphosphoglycerate and (2R)-3-phospho-glyceroyl phosphate . .
Accessions	Q6FHK8 ENST00000334828.6 Q6FHU2 P18669 Q6P6D7 Q0D2Q6

PGAM1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review