NDUFS7 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	30 studies	26% ± 9%	Explore
CD4-positive, alpha-beta T cell	26 studies	28% ± 13%	Explore
B cell	25 studies	27% ± 8%	Explore
macrophage	25 studies	35% ± 11%	Explore
CD8-positive, alpha-beta T cell	25 studies	30% ± 13%	Explore
endothelial cell	25 studies	30% ± 13%	Explore
classical monocyte	24 studies	36% ± 14%	Explore
conventional dendritic cell	24 studies	40% ± 16%	Explore
pericyte	24 studies	30% ± 10%	Explore
fibroblast	23 studies	28% ± 12%	Explore
non-classical monocyte	22 studies	41% ± 14%	Explore
T cell	21 studies	27% ± 8%	Explore
smooth muscle cell	20 studies	29% ± 9%	Explore
regulatory T cell	19 studies	32% ± 9%	Explore
epithelial cell	18 studies	36% ± 20%	Explore
monocyte	17 studies	36% ± 11%	Explore
endothelial cell of lymphatic vessel	16 studies	44% ± 14%	Explore
plasmacytoid dendritic cell	16 studies	29% ± 12%	Explore
memory B cell	15 studies	25% ± 7%	Explore
mast cell	14 studies	25% ± 13%	Explore
basal cell	14 studies	33% ± 17%	Explore
gamma-delta T cell	14 studies	29% ± 14%	Explore
plasma cell	13 studies	38% ± 14%	Explore
naive B cell	13 studies	22% ± 4%	Explore
mature NK T cell	13 studies	26% ± 5%	Explore
myofibroblast cell	13 studies	30% ± 10%	Explore
connective tissue cell	13 studies	29% ± 7%	Explore
dendritic cell	12 studies	46% ± 22%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	12 studies	22% ± 5%	Explore
CD16-positive, CD56-dim natural killer cell, human	11 studies	27% ± 7%	Explore
ciliated cell	11 studies	37% ± 16%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	11 studies	28% ± 8%	Explore
plasmablast	10 studies	46% ± 25%	Explore
CD16-negative, CD56-bright natural killer cell, human	10 studies	28% ± 5%	Explore
oligodendrocyte	10 studies	28% ± 14%	Explore
progenitor cell	9 studies	40% ± 20%	Explore
capillary endothelial cell	9 studies	24% ± 9%	Explore
mucosal invariant T cell	9 studies	24% ± 4%	Explore
myeloid cell	9 studies	32% ± 11%	Explore
CD4-positive, alpha-beta memory T cell	8 studies	31% ± 11%	Explore
CD8-positive, alpha-beta memory T cell	8 studies	32% ± 12%	Explore
type I pneumocyte	7 studies	27% ± 9%	Explore
secretory cell	7 studies	32% ± 14%	Explore
enterocyte	7 studies	42% ± 17%	Explore
goblet cell	7 studies	36% ± 11%	Explore
abnormal cell	7 studies	36% ± 11%	Explore
T follicular helper cell	7 studies	25% ± 5%	Explore
endothelial cell of vascular tree	7 studies	22% ± 5%	Explore
club cell	6 studies	30% ± 5%	Explore
respiratory goblet cell	6 studies	28% ± 17%	Explore
effector CD8-positive, alpha-beta T cell	6 studies	39% ± 15%	Explore
effector memory CD8-positive, alpha-beta T cell	6 studies	30% ± 6%	Explore
epithelial cell of proximal tubule	6 studies	45% ± 8%	Explore
renal alpha-intercalated cell	6 studies	56% ± 13%	Explore
endothelial cell of artery	6 studies	22% ± 6%	Explore
vein endothelial cell	6 studies	26% ± 8%	Explore
astrocyte	6 studies	28% ± 11%	Explore
alveolar macrophage	5 studies	29% ± 8%	Explore
leukocyte	5 studies	32% ± 12%	Explore
mononuclear phagocyte	5 studies	38% ± 19%	Explore
kidney loop of Henle epithelial cell	5 studies	47% ± 7%	Explore
mesothelial cell	5 studies	29% ± 15%	Explore
transit amplifying cell	5 studies	43% ± 18%	Explore
innate lymphoid cell	5 studies	24% ± 5%	Explore
neuron	5 studies	55% ± 15%	Explore
type II pneumocyte	5 studies	33% ± 14%	Explore
erythrocyte	5 studies	33% ± 19%	Explore
hematopoietic precursor cell	4 studies	44% ± 15%	Explore
ionocyte	4 studies	35% ± 11%	Explore
exhausted T cell	4 studies	43% ± 9%	Explore
kidney distal convoluted tubule epithelial cell	4 studies	45% ± 7%	Explore
enteroendocrine cell	4 studies	45% ± 15%	Explore
intestinal crypt stem cell	4 studies	37% ± 13%	Explore
retinal ganglion cell	4 studies	71% ± 21%	Explore
retinal cone cell	4 studies	52% ± 24%	Explore
erythroblast	4 studies	40% ± 22%	Explore
hematopoietic stem cell	4 studies	25% ± 3%	Explore
precursor B cell	4 studies	33% ± 10%	Explore
pro-B cell	4 studies	28% ± 6%	Explore
amacrine cell	4 studies	38% ± 13%	Explore
retina horizontal cell	4 studies	32% ± 14%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	41% ± 3%	Explore
intermediate monocyte	4 studies	47% ± 15%	Explore
glutamatergic neuron	4 studies	33% ± 16%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	37% ± 12%	Explore
T-helper 17 cell	4 studies	32% ± 21%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	25% ± 6%	Explore
deuterosomal cell	3 studies	21% ± 6%	Explore
duct epithelial cell	3 studies	29% ± 10%	Explore
pancreatic A cell	3 studies	46% ± 18%	Explore
neural crest cell	3 studies	33% ± 2%	Explore
retinal bipolar neuron	3 studies	39% ± 16%	Explore
OFF-bipolar cell	3 studies	43% ± 27%	Explore
lymphocyte	3 studies	37% ± 7%	Explore
immature B cell	3 studies	29% ± 6%	Explore
retinal rod cell	3 studies	33% ± 7%	Explore
microglial cell	3 studies	29% ± 10%	Explore
serous secreting cell	3 studies	37% ± 6%	Explore
intraepithelial lymphocyte	3 studies	33% ± 11%	Explore
Mueller cell	3 studies	29% ± 9%	Explore
rod bipolar cell	3 studies	30% ± 12%	Explore
germinal center B cell	3 studies	32% ± 3%	Explore
oligodendrocyte precursor cell	3 studies	34% ± 5%	Explore
granulocyte monocyte progenitor cell	3 studies	35% ± 22%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	41% ± 26%	Explore
brush cell	3 studies	24% ± 3%	Explore
glial cell	3 studies	37% ± 20%	Explore
group 3 innate lymphoid cell	3 studies	32% ± 13%	Explore
keratinocyte	3 studies	20% ± 2%	Explore
T-helper 1 cell	3 studies	34% ± 12%	Explore
double negative thymocyte	3 studies	40% ± 18%	Explore
luminal hormone-sensing cell of mammary gland	3 studies	25% ± 5%	Explore
progenitor cell of mammary luminal epithelium	3 studies	20% ± 1%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	16 studies	29% ± 11%	Explore
peripheral blood	15 studies	31% ± 9%	Explore
intestine	10 studies	32% ± 15%	Explore
kidney	8 studies	34% ± 7%	Explore
brain	8 studies	26% ± 10%	Explore
eye	6 studies	31% ± 13%	Explore
liver	6 studies	30% ± 21%	Explore
uterus	4 studies	31% ± 14%	Explore
lymph node	4 studies	32% ± 15%	Explore
bone marrow	3 studies	22% ± 5%	Explore
adrenal gland	3 studies	22% ± 6%	Explore
breast	3 studies	22% ± 3%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	2441.69	2640 / 2642	100%	5.53	705 / 705
ovary	100%	1309.55	180 / 180	100%	4.05	429 / 430
adrenal gland	100%	1833.32	258 / 258	100%	5.75	229 / 230
esophagus	100%	1800.77	1445 / 1445	99%	3.29	182 / 183
stomach	100%	1482.25	359 / 359	99%	5.74	284 / 286
kidney	100%	2306.73	89 / 89	99%	3.59	893 / 901
thymus	100%	1487.85	652 / 653	99%	3.42	600 / 605
uterus	100%	1399.96	170 / 170	99%	3.54	454 / 459
liver	100%	1346.92	225 / 226	99%	3.72	402 / 406
prostate	100%	1486.93	245 / 245	98%	3.14	494 / 502
bladder	100%	1423.19	21 / 21	98%	4.71	495 / 504
intestine	100%	1936.23	966 / 966	98%	7.60	516 / 527
skin	100%	1362.31	1808 / 1809	97%	4.07	459 / 472
lung	99%	1292.45	575 / 578	96%	2.42	1112 / 1155
pancreas	100%	903.46	328 / 328	93%	2.70	166 / 178
breast	100%	1420.44	459 / 459	91%	2.28	1019 / 1118
eye	0%	0	0 / 0	100%	6.68	80 / 80
lymph node	0%	0	0 / 0	100%	5.62	29 / 29
muscle	100%	5140.01	803 / 803	0%	0	0 / 0
spleen	100%	1622.78	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	4.11	45 / 45
ureter	0%	0	0 / 0	100%	2.89	1 / 1
adipose	100%	1421.31	1202 / 1204	0%	0	0 / 0
blood vessel	99%	1250.80	1326 / 1335	0%	0	0 / 0
heart	99%	3910.37	850 / 861	0%	0	0 / 0
peripheral blood	94%	1103.36	877 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0009060	Biological process	aerobic respiration
GO_0015990	Biological process	electron transport coupled proton transport
GO_0006120	Biological process	mitochondrial electron transport, NADH to ubiquinone
GO_0042776	Biological process	proton motive force-driven mitochondrial ATP synthesis
GO_0032981	Biological process	mitochondrial respiratory chain complex I assembly
GO_0097060	Cellular component	synaptic membrane
GO_0045271	Cellular component	respiratory chain complex I
GO_0005759	Cellular component	mitochondrial matrix
GO_0043025	Cellular component	neuronal cell body
GO_0005743	Cellular component	mitochondrial inner membrane
GO_0002020	Molecular function	protease binding
GO_0048038	Molecular function	quinone binding
GO_0051539	Molecular function	4 iron, 4 sulfur cluster binding
GO_0008137	Molecular function	NADH dehydrogenase (ubiquinone) activity
GO_0003954	Molecular function	NADH dehydrogenase activity
GO_0005515	Molecular function	protein binding
GO_0016655	Molecular function	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
GO_0046872	Molecular function	metal ion binding

IV. Literature review

[source]

Gene name	NDUFS7
Protein name	NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (EC 7.1.1.2) (Complex I-20kD) (CI-20kD) (NADH-ubiquinone oxidoreductase 20 kDa subunit) (PSST subunit) NADH:ubiquinone oxidoreductase core subunit S7 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (EC 7.1.1.2) (Complex I-20kD) (NADH-ubiquinone oxidoreductase 20 kDa subunit)
Synonyms
Description	FUNCTION: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor . Essential for the catalytic activity of complex I . .
Accessions	ENST00000414651.3 O75251 F5GXJ1 ENST00000539480.5 F5H5N1 ENST00000546283.5 [O75251-2] ENST00000233627.14 [O75251-1] F5H736 K7ENU3 ENST00000546172.7 ENST00000534853.5 ENST00000313408.11 [O75251-2]

NDUFS7 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review