Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| lung | 18 studies | 44% ± 16% | |
| peripheral blood | 15 studies | 37% ± 10% | |
| intestine | 13 studies | 36% ± 20% | |
| brain | 10 studies | 31% ± 10% | |
| kidney | 9 studies | 45% ± 13% | |
| eye | 9 studies | 40% ± 20% | |
| liver | 8 studies | 40% ± 25% | |
| bone marrow | 6 studies | 26% ± 10% | |
| pancreas | 5 studies | 46% ± 14% | |
| lymph node | 5 studies | 31% ± 7% | |
| uterus | 5 studies | 44% ± 19% | |
| placenta | 4 studies | 31% ± 13% | |
| breast | 4 studies | 29% ± 9% | |
| adrenal gland | 3 studies | 44% ± 7% | |
| esophagus | 3 studies | 50% ± 25% | |
| prostate | 3 studies | 28% ± 8% | |
| skin | 3 studies | 30% ± 8% | |
| thymus | 3 studies | 53% ± 10% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| adrenal gland | 100% | 3013.19 | 258 / 258 | 100% | 82.51 | 230 / 230 |
| esophagus | 100% | 2058.00 | 1445 / 1445 | 100% | 42.42 | 183 / 183 |
| kidney | 100% | 3075.15 | 89 / 89 | 100% | 57.80 | 901 / 901 |
| ovary | 100% | 1299.19 | 180 / 180 | 100% | 57.13 | 430 / 430 |
| prostate | 100% | 1858.81 | 245 / 245 | 100% | 79.11 | 502 / 502 |
| stomach | 100% | 1819.75 | 359 / 359 | 100% | 44.31 | 286 / 286 |
| thymus | 100% | 2209.15 | 653 / 653 | 100% | 74.14 | 605 / 605 |
| uterus | 100% | 1528.52 | 170 / 170 | 100% | 75.77 | 459 / 459 |
| brain | 100% | 2803.30 | 2639 / 2642 | 100% | 63.45 | 705 / 705 |
| breast | 100% | 1792.85 | 459 / 459 | 100% | 59.46 | 1116 / 1118 |
| intestine | 100% | 2307.63 | 966 / 966 | 100% | 50.37 | 526 / 527 |
| bladder | 100% | 1637.71 | 21 / 21 | 100% | 59.79 | 503 / 504 |
| liver | 100% | 2014.46 | 225 / 226 | 100% | 70.88 | 406 / 406 |
| lung | 99% | 1557.88 | 573 / 578 | 100% | 53.83 | 1155 / 1155 |
| pancreas | 98% | 931.51 | 322 / 328 | 100% | 55.82 | 178 / 178 |
| skin | 97% | 1293.01 | 1762 / 1809 | 100% | 55.51 | 472 / 472 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 105.81 | 29 / 29 |
| spleen | 100% | 1772.75 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 59.82 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 44.74 | 1 / 1 |
| adipose | 100% | 1801.66 | 1202 / 1204 | 0% | 0 | 0 / 0 |
| muscle | 100% | 3704.25 | 801 / 803 | 0% | 0 | 0 / 0 |
| blood vessel | 99% | 1698.21 | 1326 / 1335 | 0% | 0 | 0 / 0 |
| heart | 99% | 5518.83 | 854 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 99% | 58.71 | 79 / 80 |
| peripheral blood | 58% | 881.15 | 536 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0009060 | Biological process | aerobic respiration |
| GO_0006120 | Biological process | mitochondrial electron transport, NADH to ubiquinone |
| GO_0042776 | Biological process | proton motive force-driven mitochondrial ATP synthesis |
| GO_0055085 | Biological process | transmembrane transport |
| GO_0032981 | Biological process | mitochondrial respiratory chain complex I assembly |
| GO_0016607 | Cellular component | nuclear speck |
| GO_0045271 | Cellular component | respiratory chain complex I |
| GO_0005743 | Cellular component | mitochondrial inner membrane |
| GO_0005739 | Cellular component | mitochondrion |
| GO_0008137 | Molecular function | NADH dehydrogenase (ubiquinone) activity |
| Gene name | NDUFB1 |
| Protein name | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (Complex I-MNLL) (CI-MNLL) (NADH-ubiquinone oxidoreductase MNLL subunit) NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (Complex I-MNLL) (NADH-ubiquinone oxidoreductase MNLL subunit) |
| Synonyms | |
| Description | FUNCTION: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. . FUNCTION: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. . |
| Accessions | ENST00000605997.6 [O75438-1] O75438 ENST00000553514.5 [O75438-1] ENST00000329559.8 [O75438-1] ENST00000617122.1 [O75438-2] Q3MHU6 ENST00000555441.5 [O75438-1] |