NDUFA6 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	33 studies	33% ± 12%	Explore
fibroblast	29 studies	31% ± 13%	Explore
CD4-positive, alpha-beta T cell	28 studies	32% ± 16%	Explore
macrophage	27 studies	31% ± 12%	Explore
T cell	26 studies	32% ± 11%	Explore
CD8-positive, alpha-beta T cell	26 studies	35% ± 15%	Explore
B cell	25 studies	24% ± 7%	Explore
smooth muscle cell	25 studies	32% ± 12%	Explore
conventional dendritic cell	25 studies	34% ± 14%	Explore
pericyte	25 studies	32% ± 11%	Explore
endothelial cell	24 studies	32% ± 15%	Explore
non-classical monocyte	22 studies	40% ± 15%	Explore
classical monocyte	21 studies	31% ± 12%	Explore
regulatory T cell	20 studies	36% ± 10%	Explore
basal cell	19 studies	35% ± 18%	Explore
epithelial cell	19 studies	42% ± 21%	Explore
connective tissue cell	17 studies	34% ± 12%	Explore
mature NK T cell	16 studies	30% ± 7%	Explore
ciliated cell	16 studies	35% ± 20%	Explore
monocyte	16 studies	31% ± 9%	Explore
gamma-delta T cell	16 studies	33% ± 13%	Explore
endothelial cell of lymphatic vessel	15 studies	32% ± 12%	Explore
plasmacytoid dendritic cell	15 studies	26% ± 10%	Explore
plasma cell	14 studies	41% ± 16%	Explore
dendritic cell	14 studies	38% ± 22%	Explore
memory B cell	14 studies	25% ± 8%	Explore
mast cell	13 studies	22% ± 4%	Explore
CD16-positive, CD56-dim natural killer cell, human	13 studies	35% ± 9%	Explore
naive B cell	13 studies	20% ± 6%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	13 studies	24% ± 6%	Explore
CD16-negative, CD56-bright natural killer cell, human	12 studies	31% ± 9%	Explore
myofibroblast cell	12 studies	34% ± 12%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	11 studies	30% ± 7%	Explore
capillary endothelial cell	11 studies	26% ± 11%	Explore
goblet cell	11 studies	35% ± 16%	Explore
myeloid cell	11 studies	31% ± 10%	Explore
plasmablast	10 studies	51% ± 24%	Explore
platelet	10 studies	34% ± 9%	Explore
CD8-positive, alpha-beta memory T cell	10 studies	35% ± 11%	Explore
endothelial cell of artery	10 studies	24% ± 7%	Explore
vein endothelial cell	10 studies	25% ± 10%	Explore
mucosal invariant T cell	10 studies	28% ± 5%	Explore
CD4-positive, alpha-beta memory T cell	9 studies	32% ± 11%	Explore
secretory cell	9 studies	37% ± 20%	Explore
progenitor cell	9 studies	43% ± 12%	Explore
abnormal cell	9 studies	32% ± 14%	Explore
endothelial cell of vascular tree	9 studies	24% ± 6%	Explore
effector memory CD8-positive, alpha-beta T cell	8 studies	31% ± 9%	Explore
enterocyte	8 studies	37% ± 15%	Explore
type I pneumocyte	7 studies	29% ± 13%	Explore
club cell	7 studies	34% ± 7%	Explore
effector CD8-positive, alpha-beta T cell	7 studies	42% ± 16%	Explore
leukocyte	7 studies	30% ± 9%	Explore
epithelial cell of proximal tubule	7 studies	39% ± 11%	Explore
T follicular helper cell	7 studies	27% ± 5%	Explore
kidney loop of Henle epithelial cell	6 studies	46% ± 10%	Explore
renal alpha-intercalated cell	6 studies	69% ± 13%	Explore
transit amplifying cell	6 studies	36% ± 15%	Explore
innate lymphoid cell	6 studies	28% ± 6%	Explore
erythrocyte	6 studies	40% ± 20%	Explore
alveolar macrophage	5 studies	24% ± 6%	Explore
exhausted T cell	5 studies	41% ± 9%	Explore
ionocyte	5 studies	48% ± 10%	Explore
respiratory goblet cell	5 studies	31% ± 9%	Explore
mononuclear phagocyte	5 studies	36% ± 14%	Explore
kidney distal convoluted tubule epithelial cell	5 studies	52% ± 7%	Explore
enteroendocrine cell	5 studies	45% ± 17%	Explore
mesothelial cell	5 studies	35% ± 16%	Explore
retinal rod cell	5 studies	32% ± 17%	Explore
precursor B cell	5 studies	27% ± 10%	Explore
neuron	5 studies	38% ± 14%	Explore
type II pneumocyte	5 studies	38% ± 17%	Explore
effector CD4-positive, alpha-beta T cell	5 studies	39% ± 12%	Explore
effector memory CD4-positive, alpha-beta T cell	5 studies	40% ± 14%	Explore
hematopoietic precursor cell	4 studies	38% ± 16%	Explore
pancreatic A cell	4 studies	53% ± 8%	Explore
type B pancreatic cell	4 studies	45% ± 15%	Explore
intestinal crypt stem cell	4 studies	34% ± 11%	Explore
retinal ganglion cell	4 studies	73% ± 27%	Explore
retinal cone cell	4 studies	58% ± 25%	Explore
erythroblast	4 studies	48% ± 23%	Explore
megakaryocyte	4 studies	36% ± 14%	Explore
pro-B cell	4 studies	25% ± 6%	Explore
brush cell	4 studies	27% ± 9%	Explore
amacrine cell	4 studies	40% ± 17%	Explore
intermediate monocyte	4 studies	47% ± 13%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	32% ± 5%	Explore
granulocyte	4 studies	21% ± 4%	Explore
T-helper 17 cell	4 studies	38% ± 21%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	29% ± 7%	Explore
deuterosomal cell	3 studies	25% ± 12%	Explore
duct epithelial cell	3 studies	35% ± 13%	Explore
precursor cell	3 studies	50% ± 10%	Explore
squamous epithelial cell	3 studies	43% ± 22%	Explore
glomerular endothelial cell	3 studies	19% ± 5%	Explore
neural crest cell	3 studies	42% ± 6%	Explore
renal principal cell	3 studies	50% ± 13%	Explore
extravillous trophoblast	3 studies	53% ± 18%	Explore
placental villous trophoblast	3 studies	67% ± 12%	Explore
lymphocyte	3 studies	40% ± 8%	Explore
immature B cell	3 studies	24% ± 3%	Explore
astrocyte	3 studies	35% ± 17%	Explore
retina horizontal cell	3 studies	34% ± 17%	Explore
serous secreting cell	3 studies	41% ± 5%	Explore
intraepithelial lymphocyte	3 studies	31% ± 11%	Explore
Mueller cell	3 studies	29% ± 10%	Explore
cardiac muscle cell	3 studies	35% ± 16%	Explore
muscle cell	3 studies	37% ± 16%	Explore
IgG plasma cell	3 studies	25% ± 12%	Explore
myoepithelial cell	3 studies	30% ± 5%	Explore
pancreatic ductal cell	3 studies	63% ± 8%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	40% ± 23%	Explore
hepatocyte	3 studies	57% ± 33%	Explore
group 3 innate lymphoid cell	3 studies	38% ± 17%	Explore
keratinocyte	3 studies	27% ± 4%	Explore
T-helper 1 cell	3 studies	42% ± 13%	Explore
double negative thymocyte	3 studies	44% ± 13%	Explore
hematopoietic stem cell	3 studies	27% ± 10%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	17 studies	31% ± 8%	Explore
lung	16 studies	34% ± 16%	Explore
intestine	12 studies	30% ± 15%	Explore
kidney	9 studies	34% ± 8%	Explore
eye	7 studies	32% ± 14%	Explore
liver	6 studies	37% ± 24%	Explore
pancreas	5 studies	42% ± 16%	Explore
uterus	5 studies	29% ± 15%	Explore
brain	5 studies	23% ± 6%	Explore
lymph node	5 studies	32% ± 13%	Explore
bone marrow	4 studies	26% ± 5%	Explore
prostate	4 studies	27% ± 9%	Explore
breast	4 studies	25% ± 2%	Explore
placenta	3 studies	49% ± 20%	Explore
adrenal gland	3 studies	30% ± 3%	Explore
skin	3 studies	25% ± 3%	Explore
thymus	3 studies	42% ± 14%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	3059.86	1445 / 1445	100%	113.00	183 / 183
kidney	100%	4262.81	89 / 89	100%	160.10	901 / 901
liver	100%	2223.87	226 / 226	100%	165.40	406 / 406
ovary	100%	1584.89	180 / 180	100%	114.22	430 / 430
prostate	100%	2210.44	245 / 245	100%	131.33	502 / 502
skin	100%	2382.00	1809 / 1809	100%	152.00	472 / 472
stomach	100%	2645.95	359 / 359	100%	142.04	286 / 286
uterus	100%	1914.71	170 / 170	100%	175.94	459 / 459
breast	100%	2301.51	459 / 459	100%	137.10	1117 / 1118
brain	100%	2809.80	2638 / 2642	100%	156.06	705 / 705
thymus	100%	2239.79	652 / 653	100%	138.34	605 / 605
lung	100%	2034.04	577 / 578	100%	140.68	1155 / 1155
intestine	100%	3336.15	966 / 966	100%	148.86	526 / 527
adrenal gland	100%	3250.41	258 / 258	100%	159.53	229 / 230
bladder	100%	2577.71	21 / 21	99%	148.54	501 / 504
pancreas	98%	1147.27	322 / 328	100%	116.39	178 / 178
adipose	100%	2431.35	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	141.29	29 / 29
muscle	100%	5791.27	803 / 803	0%	0	0 / 0
spleen	100%	1922.69	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	181.59	45 / 45
ureter	0%	0	0 / 0	100%	134.64	1 / 1
blood vessel	100%	2227.23	1332 / 1335	0%	0	0 / 0
heart	99%	6455.33	852 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	99%	129.65	79 / 80
peripheral blood	71%	1182.38	658 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0009060	Biological process	aerobic respiration
GO_0006979	Biological process	response to oxidative stress
GO_0006120	Biological process	mitochondrial electron transport, NADH to ubiquinone
GO_0042776	Biological process	proton motive force-driven mitochondrial ATP synthesis
GO_0055085	Biological process	transmembrane transport
GO_0032981	Biological process	mitochondrial respiratory chain complex I assembly
GO_0031966	Cellular component	mitochondrial membrane
GO_0045271	Cellular component	respiratory chain complex I
GO_0005743	Cellular component	mitochondrial inner membrane
GO_0008137	Molecular function	NADH dehydrogenase (ubiquinone) activity

IV. Literature review

[source]

Gene name	NDUFA6
Protein name	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (Complex I-B14) (NADH-ubiquinone oxidoreductase B14 subunit) NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (Complex I-B14) (CI-B14) (LYR motif-containing protein 6) (NADH-ubiquinone oxidoreductase B14 subunit)
Synonyms	LYRM6 NADHB14
Description	FUNCTION: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Required for proper complex I assembly . Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. .
Accessions	P56556 ENST00000628198.1 ENST00000628004.1 ENST00000628740.2 ENST00000630201.4 ENST00000630971.2 ENST00000470753.1 R4GN43 ENST00000607132.1 ENST00000605927.3 ENST00000630511.1 ENST00000610887.2 ENST00000617763.1 A0A2Y9D025 ENST00000605916.1 ENST00000498737.8 ENST00000627617.1

NDUFA6 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review