LAPTM4A | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
fibroblast	45 studies	73% ± 26%	Explore
endothelial cell	43 studies	58% ± 23%	Explore
macrophage	39 studies	44% ± 15%	Explore
pericyte	35 studies	68% ± 25%	Explore
B cell	30 studies	28% ± 8%	Explore
natural killer cell	28 studies	25% ± 8%	Explore
smooth muscle cell	28 studies	67% ± 23%	Explore
mast cell	27 studies	68% ± 20%	Explore
conventional dendritic cell	26 studies	44% ± 16%	Explore
endothelial cell of lymphatic vessel	23 studies	69% ± 19%	Explore
non-classical monocyte	23 studies	46% ± 14%	Explore
epithelial cell	23 studies	58% ± 23%	Explore
classical monocyte	23 studies	39% ± 13%	Explore
monocyte	21 studies	33% ± 15%	Explore
basal cell	21 studies	62% ± 20%	Explore
CD8-positive, alpha-beta T cell	21 studies	21% ± 6%	Explore
connective tissue cell	21 studies	76% ± 21%	Explore
plasmacytoid dendritic cell	20 studies	46% ± 15%	Explore
dendritic cell	18 studies	43% ± 20%	Explore
CD4-positive, alpha-beta T cell	18 studies	20% ± 6%	Explore
T cell	17 studies	28% ± 17%	Explore
ciliated cell	17 studies	60% ± 21%	Explore
naive B cell	17 studies	24% ± 6%	Explore
memory B cell	17 studies	26% ± 7%	Explore
regulatory T cell	17 studies	25% ± 4%	Explore
capillary endothelial cell	16 studies	54% ± 22%	Explore
myofibroblast cell	14 studies	77% ± 19%	Explore
endothelial cell of artery	14 studies	57% ± 19%	Explore
mature NK T cell	13 studies	24% ± 5%	Explore
gamma-delta T cell	13 studies	24% ± 7%	Explore
secretory cell	12 studies	62% ± 15%	Explore
astrocyte	12 studies	35% ± 17%	Explore
vein endothelial cell	12 studies	60% ± 16%	Explore
endothelial cell of vascular tree	12 studies	63% ± 14%	Explore
myeloid cell	12 studies	45% ± 18%	Explore
mesothelial cell	11 studies	73% ± 24%	Explore
plasma cell	10 studies	39% ± 11%	Explore
CD16-positive, CD56-dim natural killer cell, human	10 studies	27% ± 6%	Explore
abnormal cell	10 studies	50% ± 24%	Explore
type II pneumocyte	9 studies	55% ± 21%	Explore
leukocyte	9 studies	33% ± 10%	Explore
CD16-negative, CD56-bright natural killer cell, human	9 studies	28% ± 4%	Explore
progenitor cell	9 studies	47% ± 23%	Explore
mucosal invariant T cell	9 studies	21% ± 4%	Explore
type I pneumocyte	8 studies	60% ± 15%	Explore
CD4-positive, alpha-beta memory T cell	8 studies	20% ± 5%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	8 studies	19% ± 2%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	8 studies	21% ± 3%	Explore
alveolar macrophage	7 studies	42% ± 14%	Explore
club cell	7 studies	61% ± 18%	Explore
ionocyte	7 studies	50% ± 21%	Explore
epithelial cell of proximal tubule	7 studies	60% ± 15%	Explore
goblet cell	7 studies	43% ± 20%	Explore
microglial cell	7 studies	39% ± 15%	Explore
neuron	7 studies	46% ± 23%	Explore
CD8-positive, alpha-beta memory T cell	7 studies	25% ± 5%	Explore
respiratory goblet cell	6 studies	46% ± 21%	Explore
effector CD8-positive, alpha-beta T cell	6 studies	19% ± 2%	Explore
mononuclear phagocyte	6 studies	53% ± 16%	Explore
effector memory CD8-positive, alpha-beta T cell	6 studies	28% ± 9%	Explore
kidney loop of Henle epithelial cell	6 studies	53% ± 19%	Explore
renal alpha-intercalated cell	6 studies	73% ± 10%	Explore
enterocyte	6 studies	30% ± 8%	Explore
intestinal crypt stem cell	6 studies	32% ± 9%	Explore
hematopoietic stem cell	6 studies	51% ± 15%	Explore
precursor B cell	6 studies	31% ± 12%	Explore
innate lymphoid cell	6 studies	31% ± 19%	Explore
glial cell	6 studies	50% ± 24%	Explore
T follicular helper cell	6 studies	24% ± 5%	Explore
plasmablast	5 studies	44% ± 19%	Explore
GABAergic neuron	5 studies	19% ± 3%	Explore
oligodendrocyte precursor cell	5 studies	30% ± 13%	Explore
melanocyte	5 studies	62% ± 26%	Explore
hematopoietic precursor cell	4 studies	55% ± 12%	Explore
deuterosomal cell	4 studies	24% ± 4%	Explore
duct epithelial cell	4 studies	57% ± 1%	Explore
pancreatic A cell	4 studies	66% ± 13%	Explore
type B pancreatic cell	4 studies	65% ± 20%	Explore
exhausted T cell	4 studies	24% ± 5%	Explore
glomerular endothelial cell	4 studies	66% ± 10%	Explore
podocyte	4 studies	82% ± 10%	Explore
kidney distal convoluted tubule epithelial cell	4 studies	73% ± 11%	Explore
enteroendocrine cell	4 studies	55% ± 18%	Explore
transit amplifying cell	4 studies	30% ± 7%	Explore
brush cell	4 studies	38% ± 21%	Explore
immature B cell	4 studies	26% ± 10%	Explore
pro-B cell	4 studies	33% ± 9%	Explore
adventitial cell	4 studies	82% ± 16%	Explore
mucus secreting cell	4 studies	42% ± 12%	Explore
acinar cell	4 studies	49% ± 23%	Explore
muscle cell	4 studies	47% ± 21%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	20% ± 1%	Explore
intermediate monocyte	4 studies	43% ± 19%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	24% ± 11%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	73% ± 10%	Explore
adipocyte	4 studies	38% ± 36%	Explore
granulocyte	4 studies	72% ± 24%	Explore
luminal cell of prostate epithelium	4 studies	34% ± 13%	Explore
glutamatergic neuron	4 studies	30% ± 7%	Explore
hepatocyte	4 studies	48% ± 27%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	22% ± 5%	Explore
hillock cell	3 studies	28% ± 11%	Explore
precursor cell	3 studies	53% ± 9%	Explore
squamous epithelial cell	3 studies	53% ± 20%	Explore
pancreatic D cell	3 studies	71% ± 17%	Explore
monocyte-derived dendritic cell	3 studies	49% ± 11%	Explore
kidney connecting tubule epithelial cell	3 studies	76% ± 9%	Explore
neural crest cell	3 studies	61% ± 7%	Explore
renal principal cell	3 studies	77% ± 13%	Explore
extravillous trophoblast	3 studies	78% ± 21%	Explore
placental villous trophoblast	3 studies	39% ± 10%	Explore
Schwann cell	3 studies	55% ± 24%	Explore
retinal pigment epithelial cell	3 studies	45% ± 31%	Explore
serous secreting cell	3 studies	48% ± 3%	Explore
tissue-resident macrophage	3 studies	45% ± 18%	Explore
lymphocyte	3 studies	71% ± 15%	Explore
Mueller cell	3 studies	60% ± 12%	Explore
chondrocyte	3 studies	64% ± 27%	Explore
endothelial cell of sinusoid	3 studies	49% ± 26%	Explore
myoepithelial cell	3 studies	82% ± 6%	Explore
inflammatory macrophage	3 studies	30% ± 4%	Explore
pancreatic ductal cell	3 studies	84% ± 6%	Explore
group 3 innate lymphoid cell	3 studies	25% ± 9%	Explore
keratinocyte	3 studies	63% ± 14%	Explore
interneuron	3 studies	40% ± 25%	Explore
double negative thymocyte	3 studies	33% ± 10%	Explore
progenitor cell of mammary luminal epithelium	3 studies	56% ± 13%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	18 studies	53% ± 20%	Explore
peripheral blood	15 studies	29% ± 9%	Explore
intestine	12 studies	41% ± 24%	Explore
brain	9 studies	27% ± 13%	Explore
kidney	9 studies	51% ± 15%	Explore
eye	9 studies	27% ± 15%	Explore
pancreas	5 studies	59% ± 22%	Explore
placenta	5 studies	47% ± 14%	Explore
uterus	5 studies	67% ± 17%	Explore
prostate	5 studies	46% ± 19%	Explore
lymph node	5 studies	35% ± 17%	Explore
liver	5 studies	36% ± 13%	Explore
bone marrow	4 studies	27% ± 9%	Explore
adipose	4 studies	33% ± 4%	Explore
breast	4 studies	57% ± 8%	Explore
heart	3 studies	35% ± 10%	Explore
adrenal gland	3 studies	37% ± 7%	Explore
esophagus	3 studies	55% ± 29%	Explore
skin	3 studies	69% ± 6%	Explore
thymus	3 studies	39% ± 9%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	14363.24	1445 / 1445	100%	543.71	183 / 183
lung	100%	17363.40	578 / 578	100%	689.14	1155 / 1155
ovary	100%	20477.03	180 / 180	100%	728.12	430 / 430
stomach	100%	11741.23	359 / 359	100%	530.74	286 / 286
uterus	100%	23817.41	170 / 170	100%	766.48	458 / 459
breast	100%	20046.39	459 / 459	100%	995.79	1115 / 1118
pancreas	100%	9273.68	327 / 328	100%	731.67	178 / 178
intestine	100%	15106.36	966 / 966	100%	543.00	525 / 527
prostate	100%	13066.60	245 / 245	100%	634.95	500 / 502
skin	100%	17492.41	1809 / 1809	100%	592.78	470 / 472
kidney	100%	14833.75	89 / 89	100%	938.82	897 / 901
thymus	100%	16211.59	653 / 653	100%	834.64	602 / 605
liver	100%	8214.67	226 / 226	99%	484.45	403 / 406
bladder	100%	15936.52	21 / 21	99%	655.82	500 / 504
adrenal gland	100%	20875.62	258 / 258	98%	696.17	225 / 230
brain	93%	4851.80	2460 / 2642	100%	522.00	703 / 705
adipose	100%	21261.62	1204 / 1204	0%	0	0 / 0
blood vessel	100%	19525.68	1335 / 1335	0%	0	0 / 0
spleen	100%	8696.51	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	501.46	45 / 45
ureter	0%	0	0 / 0	100%	296.05	1 / 1
eye	0%	0	0 / 0	99%	509.24	79 / 80
heart	98%	10658.24	846 / 861	0%	0	0 / 0
muscle	98%	5445.62	787 / 803	0%	0	0 / 0
lymph node	0%	0	0 / 0	97%	211.04	28 / 29
peripheral blood	81%	4865.12	753 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

IV. Literature review

[source]

Gene name	LAPTM4A
Protein name	Lysosomal-associated transmembrane protein 4A (Golgi 4-transmembrane-spanning transporter MTP) Lysosomal-associated transmembrane protein 4A Uncharacterized protein LAPTM4A
Synonyms	KIAA0108 MTRP hCG_32086 MBNT LAPTM4 UNQ1846/PRO3574
Description	FUNCTION: May function in the transport of nucleosides and/or nucleoside derivatives between the cytosol and the lumen of an intracellular membrane-bound compartment. . FUNCTION: May function in the transport of nucleosides and/or nucleoside derivatives between the cytosol and the lumen of an intracellular membrane-bound compartment. . FUNCTION: May function in the transport of nucleosides and/or nucleoside derivatives between the cytosol and the lumen of an intracellular membrane-bound compartment. . FUNCTION: May function in the transport of nucleosides and/or nucleoside derivatives between the cytosol and the lumen of an intracellular membrane-bound compartment. .
Accessions	ENST00000175091.5 Q6IBP4 Q15012 Q53QZ6 Q4ZG00 Q9BTU8

GO_0005765	Cellular component	lysosomal membrane
GO_0005794	Cellular component	Golgi apparatus
GO_0031902	Cellular component	late endosome membrane
GO_0005515	Molecular function	protein binding

LAPTM4A report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review