DRAP1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	38 studies	46% ± 14%	Explore
CD8-positive, alpha-beta T cell	36 studies	43% ± 17%	Explore
B cell	32 studies	30% ± 12%	Explore
fibroblast	32 studies	36% ± 13%	Explore
CD4-positive, alpha-beta T cell	32 studies	38% ± 13%	Explore
macrophage	30 studies	42% ± 13%	Explore
T cell	27 studies	39% ± 12%	Explore
conventional dendritic cell	26 studies	49% ± 13%	Explore
classical monocyte	25 studies	37% ± 14%	Explore
regulatory T cell	24 studies	39% ± 15%	Explore
endothelial cell	24 studies	32% ± 13%	Explore
smooth muscle cell	23 studies	37% ± 12%	Explore
non-classical monocyte	23 studies	69% ± 18%	Explore
pericyte	23 studies	35% ± 11%	Explore
mature NK T cell	19 studies	42% ± 12%	Explore
plasmacytoid dendritic cell	19 studies	39% ± 12%	Explore
monocyte	18 studies	42% ± 14%	Explore
gamma-delta T cell	18 studies	43% ± 15%	Explore
naive B cell	18 studies	30% ± 8%	Explore
dendritic cell	17 studies	45% ± 23%	Explore
mast cell	17 studies	43% ± 15%	Explore
memory B cell	17 studies	27% ± 5%	Explore
basal cell	16 studies	37% ± 14%	Explore
CD16-negative, CD56-bright natural killer cell, human	15 studies	48% ± 15%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	15 studies	33% ± 9%	Explore
CD16-positive, CD56-dim natural killer cell, human	15 studies	50% ± 13%	Explore
connective tissue cell	15 studies	41% ± 12%	Explore
mucosal invariant T cell	14 studies	35% ± 11%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	14 studies	43% ± 15%	Explore
epithelial cell	14 studies	40% ± 17%	Explore
endothelial cell of lymphatic vessel	13 studies	30% ± 11%	Explore
plasma cell	13 studies	37% ± 13%	Explore
myofibroblast cell	13 studies	39% ± 13%	Explore
CD8-positive, alpha-beta memory T cell	12 studies	45% ± 19%	Explore
capillary endothelial cell	12 studies	23% ± 6%	Explore
CD4-positive, alpha-beta memory T cell	11 studies	41% ± 18%	Explore
plasmablast	10 studies	47% ± 27%	Explore
vein endothelial cell	10 studies	24% ± 6%	Explore
endothelial cell of vascular tree	10 studies	27% ± 5%	Explore
myeloid cell	10 studies	46% ± 15%	Explore
effector memory CD8-positive, alpha-beta T cell	9 studies	44% ± 15%	Explore
ciliated cell	9 studies	35% ± 18%	Explore
innate lymphoid cell	8 studies	39% ± 12%	Explore
secretory cell	8 studies	35% ± 17%	Explore
abnormal cell	8 studies	39% ± 14%	Explore
endothelial cell of artery	8 studies	27% ± 7%	Explore
hematopoietic stem cell	8 studies	43% ± 19%	Explore
platelet	7 studies	21% ± 5%	Explore
leukocyte	7 studies	39% ± 11%	Explore
T follicular helper cell	7 studies	35% ± 9%	Explore
hematopoietic precursor cell	6 studies	47% ± 31%	Explore
effector CD8-positive, alpha-beta T cell	6 studies	51% ± 12%	Explore
neuron	6 studies	47% ± 20%	Explore
precursor B cell	6 studies	33% ± 11%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	45% ± 18%	Explore
alveolar macrophage	5 studies	36% ± 8%	Explore
CD4-positive helper T cell	5 studies	26% ± 10%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	5 studies	35% ± 8%	Explore
exhausted T cell	5 studies	66% ± 12%	Explore
mononuclear phagocyte	5 studies	53% ± 16%	Explore
kidney loop of Henle epithelial cell	5 studies	21% ± 2%	Explore
epithelial cell of proximal tubule	5 studies	20% ± 3%	Explore
mesothelial cell	5 studies	37% ± 16%	Explore
pro-B cell	5 studies	30% ± 6%	Explore
club cell	5 studies	22% ± 8%	Explore
immature B cell	5 studies	41% ± 20%	Explore
intermediate monocyte	5 studies	57% ± 17%	Explore
granulocyte	5 studies	40% ± 18%	Explore
central memory CD8-positive, alpha-beta T cell	4 studies	29% ± 7%	Explore
progenitor cell	4 studies	43% ± 9%	Explore
astrocyte	4 studies	27% ± 17%	Explore
oligodendrocyte	4 studies	23% ± 6%	Explore
enteroendocrine cell	4 studies	39% ± 17%	Explore
retinal ganglion cell	4 studies	52% ± 29%	Explore
erythroblast	4 studies	41% ± 21%	Explore
type I pneumocyte	4 studies	31% ± 9%	Explore
microglial cell	4 studies	31% ± 14%	Explore
adventitial cell	4 studies	22% ± 7%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	63% ± 16%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	34% ± 4%	Explore
oligodendrocyte precursor cell	4 studies	29% ± 11%	Explore
goblet cell	4 studies	26% ± 11%	Explore
erythrocyte	4 studies	46% ± 19%	Explore
group 3 innate lymphoid cell	4 studies	56% ± 14%	Explore
T-helper 17 cell	4 studies	46% ± 12%	Explore
T-helper 1 cell	4 studies	52% ± 11%	Explore
double negative thymocyte	4 studies	53% ± 19%	Explore
CD4-positive, alpha-beta cytotoxic T cell	3 studies	50% ± 20%	Explore
pancreatic A cell	3 studies	47% ± 19%	Explore
glomerular endothelial cell	3 studies	23% ± 2%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	32% ± 4%	Explore
neural crest cell	3 studies	31% ± 6%	Explore
lymphocyte	3 studies	47% ± 15%	Explore
megakaryocyte	3 studies	39% ± 6%	Explore
neuroendocrine cell	3 studies	34% ± 12%	Explore
type II pneumocyte	3 studies	31% ± 9%	Explore
amacrine cell	3 studies	44% ± 18%	Explore
retina horizontal cell	3 studies	42% ± 14%	Explore
retinal cone cell	3 studies	52% ± 16%	Explore
retinal rod cell	3 studies	26% ± 9%	Explore
intraepithelial lymphocyte	3 studies	55% ± 6%	Explore
Mueller cell	3 studies	22% ± 5%	Explore
germinal center B cell	3 studies	19% ± 2%	Explore
myoepithelial cell	3 studies	46% ± 6%	Explore
luminal cell of prostate epithelium	3 studies	24% ± 7%	Explore
glutamatergic neuron	3 studies	32% ± 9%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	56% ± 28%	Explore
neutrophil	3 studies	20% ± 3%	Explore
glial cell	3 studies	35% ± 17%	Explore
keratinocyte	3 studies	52% ± 28%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	35% ± 10%	Explore
progenitor cell of mammary luminal epithelium	3 studies	27% ± 9%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	18 studies	42% ± 12%	Explore
lung	17 studies	35% ± 15%	Explore
intestine	9 studies	28% ± 13%	Explore
kidney	7 studies	35% ± 11%	Explore
brain	6 studies	29% ± 8%	Explore
eye	6 studies	28% ± 11%	Explore
bone marrow	5 studies	26% ± 11%	Explore
lymph node	5 studies	35% ± 10%	Explore
uterus	4 studies	40% ± 17%	Explore
breast	4 studies	35% ± 2%	Explore
liver	4 studies	43% ± 21%	Explore
pancreas	3 studies	38% ± 19%	Explore
prostate	3 studies	33% ± 8%	Explore
placenta	3 studies	26% ± 8%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
adrenal gland	100%	3358.79	258 / 258	100%	155.97	230 / 230
esophagus	100%	3793.15	1445 / 1445	100%	110.33	183 / 183
ovary	100%	2577.14	180 / 180	100%	164.49	430 / 430
thymus	100%	5281.91	653 / 653	100%	327.45	605 / 605
uterus	100%	3487.47	170 / 170	100%	199.87	459 / 459
brain	100%	4526.96	2639 / 2642	100%	197.97	705 / 705
skin	100%	6214.63	1809 / 1809	100%	180.77	471 / 472
liver	100%	1671.15	225 / 226	100%	125.99	406 / 406
intestine	100%	3414.56	966 / 966	99%	123.41	524 / 527
stomach	100%	2335.51	358 / 359	99%	110.99	284 / 286
kidney	100%	2732.65	89 / 89	99%	103.09	892 / 901
prostate	100%	3117.98	244 / 245	99%	148.94	499 / 502
breast	100%	3340.64	459 / 459	98%	155.63	1101 / 1118
bladder	100%	3473.57	21 / 21	98%	171.87	496 / 504
lung	100%	3128.46	576 / 578	99%	134.93	1139 / 1155
pancreas	97%	1288.48	319 / 328	99%	139.82	176 / 178
adipose	100%	3413.41	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	105.34	80 / 80
lymph node	0%	0	0 / 0	100%	236.58	29 / 29
spleen	100%	3466.28	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	196.19	45 / 45
ureter	0%	0	0 / 0	100%	319.25	1 / 1
blood vessel	100%	4340.77	1334 / 1335	0%	0	0 / 0
muscle	100%	3758.02	801 / 803	0%	0	0 / 0
peripheral blood	99%	3581.09	918 / 929	0%	0	0 / 0
heart	98%	3059.25	842 / 861	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0006366	Biological process	transcription by RNA polymerase II
GO_0000122	Biological process	negative regulation of transcription by RNA polymerase II
GO_0090575	Cellular component	RNA polymerase II transcription regulator complex
GO_0017054	Cellular component	negative cofactor 2 complex
GO_0005634	Cellular component	nucleus
GO_0046982	Molecular function	protein heterodimerization activity
GO_0003677	Molecular function	DNA binding
GO_0017025	Molecular function	TBP-class protein binding
GO_0016251	Molecular function	RNA polymerase II general transcription initiation factor activity
GO_0001091	Molecular function	RNA polymerase II general transcription initiation factor binding
GO_0001046	Molecular function	core promoter sequence-specific DNA binding
GO_0042802	Molecular function	identical protein binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	DRAP1
Protein name	DR1 associated protein 1 Dr1-associated corepressor (Dr1-associated protein 1) (Negative cofactor 2-alpha) (NC2-alpha)
Synonyms
Description	FUNCTION: The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own. .
Accessions	ENST00000376991.6 ENST00000532933.1 E9PMW2 ENST00000525501.5 C9JCC6 E9PQX9 E9PNC7 Q14919 ENST00000527119.5 ENST00000312515.7 [Q14919-1]

DRAP1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review