CCT6A | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
B cell	31 studies	25% ± 7%	Explore
natural killer cell	30 studies	29% ± 13%	Explore
endothelial cell	30 studies	32% ± 13%	Explore
conventional dendritic cell	25 studies	36% ± 14%	Explore
macrophage	23 studies	26% ± 9%	Explore
fibroblast	23 studies	26% ± 9%	Explore
CD4-positive, alpha-beta T cell	23 studies	31% ± 17%	Explore
CD8-positive, alpha-beta T cell	23 studies	32% ± 15%	Explore
pericyte	23 studies	27% ± 10%	Explore
smooth muscle cell	21 studies	29% ± 9%	Explore
regulatory T cell	21 studies	31% ± 14%	Explore
T cell	20 studies	28% ± 9%	Explore
basal cell	20 studies	31% ± 15%	Explore
non-classical monocyte	19 studies	29% ± 12%	Explore
memory B cell	18 studies	25% ± 12%	Explore
classical monocyte	18 studies	26% ± 10%	Explore
plasmacytoid dendritic cell	16 studies	28% ± 10%	Explore
ciliated cell	16 studies	41% ± 17%	Explore
epithelial cell	16 studies	39% ± 20%	Explore
endothelial cell of lymphatic vessel	14 studies	33% ± 10%	Explore
gamma-delta T cell	14 studies	30% ± 15%	Explore
monocyte	13 studies	27% ± 8%	Explore
CD16-positive, CD56-dim natural killer cell, human	13 studies	25% ± 6%	Explore
dendritic cell	12 studies	44% ± 23%	Explore
mast cell	12 studies	23% ± 7%	Explore
naive B cell	12 studies	24% ± 5%	Explore
CD16-negative, CD56-bright natural killer cell, human	12 studies	29% ± 9%	Explore
mature NK T cell	12 studies	25% ± 7%	Explore
capillary endothelial cell	12 studies	25% ± 13%	Explore
connective tissue cell	12 studies	32% ± 12%	Explore
vein endothelial cell	12 studies	29% ± 11%	Explore
endothelial cell of vascular tree	12 studies	28% ± 11%	Explore
CD8-positive, alpha-beta memory T cell	11 studies	28% ± 9%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	11 studies	24% ± 5%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	11 studies	27% ± 7%	Explore
myofibroblast cell	11 studies	32% ± 13%	Explore
CD4-positive, alpha-beta memory T cell	10 studies	26% ± 9%	Explore
abnormal cell	10 studies	35% ± 14%	Explore
mucosal invariant T cell	10 studies	26% ± 6%	Explore
secretory cell	9 studies	30% ± 15%	Explore
myeloid cell	9 studies	30% ± 13%	Explore
plasmablast	8 studies	46% ± 23%	Explore
endothelial cell of artery	8 studies	25% ± 3%	Explore
effector memory CD8-positive, alpha-beta T cell	7 studies	26% ± 4%	Explore
neuron	7 studies	43% ± 21%	Explore
innate lymphoid cell	7 studies	29% ± 6%	Explore
type II pneumocyte	6 studies	26% ± 13%	Explore
effector CD8-positive, alpha-beta T cell	6 studies	38% ± 17%	Explore
leukocyte	6 studies	30% ± 9%	Explore
epithelial cell of proximal tubule	6 studies	23% ± 6%	Explore
progenitor cell	6 studies	45% ± 9%	Explore
goblet cell	6 studies	24% ± 8%	Explore
transit amplifying cell	6 studies	25% ± 3%	Explore
astrocyte	6 studies	21% ± 7%	Explore
erythrocyte	6 studies	38% ± 29%	Explore
type I pneumocyte	5 studies	30% ± 8%	Explore
hematopoietic precursor cell	5 studies	48% ± 21%	Explore
plasma cell	5 studies	42% ± 23%	Explore
club cell	5 studies	29% ± 9%	Explore
enteroendocrine cell	5 studies	34% ± 13%	Explore
mesothelial cell	5 studies	39% ± 15%	Explore
erythroblast	5 studies	55% ± 20%	Explore
hematopoietic stem cell	5 studies	47% ± 11%	Explore
precursor B cell	5 studies	37% ± 14%	Explore
pro-B cell	5 studies	38% ± 7%	Explore
T follicular helper cell	5 studies	22% ± 2%	Explore
effector memory CD4-positive, alpha-beta T cell	5 studies	32% ± 8%	Explore
GABAergic neuron	5 studies	30% ± 11%	Explore
glutamatergic neuron	5 studies	39% ± 12%	Explore
deuterosomal cell	4 studies	39% ± 5%	Explore
respiratory goblet cell	4 studies	32% ± 17%	Explore
pancreatic A cell	4 studies	47% ± 18%	Explore
mononuclear phagocyte	4 studies	34% ± 15%	Explore
exhausted T cell	4 studies	30% ± 7%	Explore
kidney loop of Henle epithelial cell	4 studies	21% ± 4%	Explore
intestinal crypt stem cell	4 studies	29% ± 7%	Explore
retinal ganglion cell	4 studies	52% ± 29%	Explore
immature B cell	4 studies	29% ± 10%	Explore
microglial cell	4 studies	26% ± 7%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	39% ± 8%	Explore
interneuron	4 studies	30% ± 9%	Explore
oligodendrocyte	4 studies	23% ± 6%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	24% ± 7%	Explore
oligodendrocyte precursor cell	4 studies	34% ± 10%	Explore
precursor cell	3 studies	63% ± 13%	Explore
type B pancreatic cell	3 studies	53% ± 18%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	41% ± 14%	Explore
renal alpha-intercalated cell	3 studies	31% ± 9%	Explore
enterocyte	3 studies	25% ± 6%	Explore
neural crest cell	3 studies	49% ± 9%	Explore
extravillous trophoblast	3 studies	28% ± 5%	Explore
placental villous trophoblast	3 studies	44% ± 3%	Explore
common myeloid progenitor	3 studies	36% ± 23%	Explore
lymphocyte	3 studies	37% ± 7%	Explore
retina horizontal cell	3 studies	28% ± 14%	Explore
retinal cone cell	3 studies	33% ± 11%	Explore
Mueller cell	3 studies	19% ± 3%	Explore
CD4-positive helper T cell	3 studies	38% ± 15%	Explore
germinal center B cell	3 studies	30% ± 10%	Explore
intermediate monocyte	3 studies	40% ± 14%	Explore
luminal hormone-sensing cell of mammary gland	3 studies	31% ± 8%	Explore
pancreatic ductal cell	3 studies	58% ± 17%	Explore
granulocyte monocyte progenitor cell	3 studies	39% ± 23%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	57% ± 20%	Explore
group 3 innate lymphoid cell	3 studies	39% ± 18%	Explore
keratinocyte	3 studies	23% ± 4%	Explore
T-helper 17 cell	3 studies	40% ± 23%	Explore
T-helper 1 cell	3 studies	35% ± 12%	Explore
double negative thymocyte	3 studies	42% ± 21%	Explore
progenitor cell of mammary luminal epithelium	3 studies	23% ± 6%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	16 studies	31% ± 14%	Explore
peripheral blood	14 studies	30% ± 9%	Explore
brain	8 studies	28% ± 7%	Explore
kidney	7 studies	26% ± 7%	Explore
intestine	7 studies	28% ± 12%	Explore
eye	6 studies	24% ± 10%	Explore
liver	6 studies	31% ± 20%	Explore
bone marrow	5 studies	24% ± 4%	Explore
lymph node	5 studies	32% ± 14%	Explore
pancreas	4 studies	46% ± 20%	Explore
uterus	4 studies	33% ± 17%	Explore
breast	4 studies	25% ± 5%	Explore
placenta	3 studies	31% ± 6%	Explore
prostate	3 studies	23% ± 7%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	7654.97	1445 / 1445	100%	219.05	183 / 183
ovary	100%	5861.86	180 / 180	100%	132.96	430 / 430
stomach	100%	5959.85	359 / 359	100%	206.65	286 / 286
uterus	100%	6871.26	170 / 170	100%	221.85	459 / 459
bladder	100%	8008.05	21 / 21	100%	217.38	503 / 504
skin	100%	10429.73	1809 / 1809	100%	261.33	471 / 472
breast	100%	7173.41	459 / 459	100%	236.14	1115 / 1118
intestine	100%	6928.02	966 / 966	100%	232.91	525 / 527
brain	100%	5652.46	2629 / 2642	100%	244.03	705 / 705
lung	99%	6616.82	575 / 578	100%	244.65	1155 / 1155
prostate	100%	5920.51	245 / 245	99%	143.32	498 / 502
thymus	100%	6065.53	653 / 653	99%	126.78	600 / 605
kidney	100%	6629.28	89 / 89	99%	128.08	891 / 901
liver	100%	3753.73	225 / 226	99%	114.26	402 / 406
pancreas	99%	5010.70	326 / 328	99%	150.58	176 / 178
adrenal gland	100%	8273.75	258 / 258	98%	139.47	226 / 230
adipose	100%	7611.08	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	219.26	29 / 29
muscle	100%	9798.34	803 / 803	0%	0	0 / 0
spleen	100%	6430.66	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	211.39	45 / 45
ureter	0%	0	0 / 0	100%	76.87	1 / 1
blood vessel	100%	7349.37	1334 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	96%	155.28	77 / 80
heart	96%	4935.80	826 / 861	0%	0	0 / 0
peripheral blood	76%	5535.58	710 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_1904871	Biological process	positive regulation of protein localization to Cajal body
GO_0061077	Biological process	chaperone-mediated protein folding
GO_1904874	Biological process	positive regulation of telomerase RNA localization to Cajal body
GO_1904851	Biological process	positive regulation of establishment of protein localization to telomere
GO_0006457	Biological process	protein folding
GO_0050821	Biological process	protein stabilization
GO_0032212	Biological process	positive regulation of telomere maintenance via telomerase
GO_0005874	Cellular component	microtubule
GO_0005832	Cellular component	chaperonin-containing T-complex
GO_0070062	Cellular component	extracellular exosome
GO_0005829	Cellular component	cytosol
GO_0005737	Cellular component	cytoplasm
GO_0044183	Molecular function	protein folding chaperone
GO_0051082	Molecular function	unfolded protein binding
GO_0140662	Molecular function	ATP-dependent protein folding chaperone
GO_0005524	Molecular function	ATP binding
GO_0003723	Molecular function	RNA binding
GO_0071987	Molecular function	WD40-repeat domain binding
GO_0005515	Molecular function	protein binding
GO_0016887	Molecular function	ATP hydrolysis activity

IV. Literature review

[source]

Gene name	CCT6A
Protein name	T-complex protein 1 subunit zeta (TCP-1-zeta) (Acute morphine dependence-related protein 2) (CCT-zeta-1) (HTR3) (Tcp20) T-complex protein 1 subunit zeta
Synonyms	CCT6 CCTZ
Description	FUNCTION: Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis . The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance . The TRiC complex plays a role in the folding of actin and tubulin (Probable). .
Accessions	P40227 ENST00000335503.3 [P40227-2] ENST00000275603.9 [P40227-1] A1JUI8

CCT6A report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review