ATP5MK report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0015986Biological processproton motive force-driven ATP synthesis
GO_0005743Cellular componentmitochondrial inner membrane
GO_0005753Cellular componentmitochondrial proton-transporting ATP synthase complex
GO_0005739Cellular componentmitochondrion

IV. Literature review

[source]
Gene nameATP5MK
Protein nameATP synthase membrane subunit K, mitochondrial (ATP synthase membrane subunit DAPIT, mitochondrial) (Diabetes-associated protein in insulin-sensitive tissues) (HCV F-transactivated protein 2) (Up-regulated during skeletal muscle growth protein 5)
SynonymsUSMG5
PD04912
DAPIT
HCVFTP2
ATP5MD
DescriptionFUNCTION: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation . ATP5MK is a minor subunit of the mitochondrial membrane ATP synthase required for dimerization of the ATP synthase complex and as such regulates ATP synthesis in the mitochondria . .

AccessionsENST00000309579.7
ENST00000369811.5
ENST00000337003.4
ENST00000369815.6
ENST00000369825.6
Q96IX5