APRT | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
B cell	38 studies	45% ± 13%	Explore
natural killer cell	38 studies	48% ± 13%	Explore
CD8-positive, alpha-beta T cell	36 studies	51% ± 17%	Explore
CD4-positive, alpha-beta T cell	33 studies	57% ± 16%	Explore
fibroblast	32 studies	34% ± 12%	Explore
T cell	31 studies	47% ± 13%	Explore
macrophage	29 studies	42% ± 11%	Explore
endothelial cell	29 studies	35% ± 14%	Explore
conventional dendritic cell	27 studies	58% ± 16%	Explore
regulatory T cell	26 studies	55% ± 15%	Explore
classical monocyte	25 studies	48% ± 14%	Explore
plasmacytoid dendritic cell	24 studies	60% ± 14%	Explore
non-classical monocyte	23 studies	48% ± 16%	Explore
dendritic cell	22 studies	52% ± 22%	Explore
smooth muscle cell	21 studies	26% ± 8%	Explore
mature NK T cell	21 studies	49% ± 15%	Explore
epithelial cell	21 studies	49% ± 19%	Explore
memory B cell	20 studies	46% ± 10%	Explore
naive B cell	20 studies	41% ± 10%	Explore
pericyte	20 studies	29% ± 8%	Explore
monocyte	18 studies	44% ± 13%	Explore
gamma-delta T cell	18 studies	50% ± 14%	Explore
basal cell	18 studies	51% ± 14%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	17 studies	55% ± 16%	Explore
endothelial cell of lymphatic vessel	16 studies	39% ± 13%	Explore
mucosal invariant T cell	16 studies	52% ± 15%	Explore
mast cell	15 studies	29% ± 15%	Explore
CD16-negative, CD56-bright natural killer cell, human	15 studies	51% ± 16%	Explore
plasma cell	15 studies	49% ± 18%	Explore
CD16-positive, CD56-dim natural killer cell, human	15 studies	50% ± 14%	Explore
ciliated cell	15 studies	39% ± 17%	Explore
connective tissue cell	15 studies	35% ± 12%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	14 studies	60% ± 15%	Explore
CD8-positive, alpha-beta memory T cell	12 studies	49% ± 15%	Explore
myofibroblast cell	12 studies	32% ± 9%	Explore
myeloid cell	12 studies	46% ± 18%	Explore
plasmablast	11 studies	53% ± 21%	Explore
CD4-positive, alpha-beta memory T cell	11 studies	54% ± 18%	Explore
secretory cell	11 studies	42% ± 17%	Explore
vein endothelial cell	11 studies	34% ± 11%	Explore
endothelial cell of vascular tree	11 studies	33% ± 9%	Explore
effector memory CD8-positive, alpha-beta T cell	10 studies	51% ± 19%	Explore
innate lymphoid cell	10 studies	47% ± 12%	Explore
capillary endothelial cell	10 studies	29% ± 11%	Explore
abnormal cell	10 studies	38% ± 15%	Explore
endothelial cell of artery	10 studies	29% ± 7%	Explore
goblet cell	10 studies	39% ± 18%	Explore
progenitor cell	9 studies	54% ± 18%	Explore
mesothelial cell	9 studies	44% ± 18%	Explore
T follicular helper cell	9 studies	51% ± 13%	Explore
type I pneumocyte	8 studies	35% ± 17%	Explore
type II pneumocyte	8 studies	48% ± 22%	Explore
leukocyte	8 studies	43% ± 12%	Explore
hematopoietic stem cell	8 studies	55% ± 22%	Explore
club cell	7 studies	47% ± 8%	Explore
effector CD8-positive, alpha-beta T cell	7 studies	54% ± 18%	Explore
hematopoietic precursor cell	6 studies	53% ± 28%	Explore
respiratory goblet cell	6 studies	41% ± 21%	Explore
effector CD4-positive, alpha-beta T cell	6 studies	61% ± 22%	Explore
epithelial cell of proximal tubule	6 studies	45% ± 9%	Explore
renal alpha-intercalated cell	6 studies	42% ± 8%	Explore
intestinal crypt stem cell	6 studies	43% ± 17%	Explore
transit amplifying cell	6 studies	40% ± 18%	Explore
erythrocyte	6 studies	43% ± 25%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	65% ± 17%	Explore
alveolar macrophage	5 studies	33% ± 7%	Explore
CD4-positive helper T cell	5 studies	44% ± 8%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	5 studies	46% ± 14%	Explore
exhausted T cell	5 studies	63% ± 8%	Explore
ionocyte	5 studies	31% ± 11%	Explore
mononuclear phagocyte	5 studies	56% ± 16%	Explore
kidney loop of Henle epithelial cell	5 studies	31% ± 6%	Explore
enterocyte	5 studies	39% ± 8%	Explore
erythroblast	5 studies	44% ± 19%	Explore
precursor B cell	5 studies	42% ± 18%	Explore
pro-B cell	5 studies	33% ± 10%	Explore
T-helper 17 cell	5 studies	64% ± 15%	Explore
immature B cell	5 studies	61% ± 11%	Explore
double negative thymocyte	5 studies	65% ± 12%	Explore
intermediate monocyte	5 studies	63% ± 14%	Explore
central memory CD8-positive, alpha-beta T cell	4 studies	55% ± 14%	Explore
platelet	4 studies	23% ± 8%	Explore
pancreatic A cell	4 studies	39% ± 20%	Explore
enteroendocrine cell	4 studies	51% ± 12%	Explore
IgA plasma cell	4 studies	25% ± 10%	Explore
IgG plasma cell	4 studies	26% ± 11%	Explore
adventitial cell	4 studies	41% ± 5%	Explore
mucus secreting cell	4 studies	48% ± 23%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	53% ± 7%	Explore
granulocyte	4 studies	38% ± 13%	Explore
group 3 innate lymphoid cell	4 studies	57% ± 13%	Explore
T-helper 1 cell	4 studies	63% ± 13%	Explore
CD4-positive, alpha-beta cytotoxic T cell	3 studies	55% ± 18%	Explore
deuterosomal cell	3 studies	42% ± 4%	Explore
duct epithelial cell	3 studies	46% ± 6%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	45% ± 6%	Explore
neural crest cell	3 studies	34% ± 12%	Explore
thymocyte	3 studies	44% ± 30%	Explore
extravillous trophoblast	3 studies	50% ± 17%	Explore
placental villous trophoblast	3 studies	50% ± 16%	Explore
common myeloid progenitor	3 studies	53% ± 28%	Explore
lymphocyte	3 studies	52% ± 15%	Explore
megakaryocyte	3 studies	39% ± 8%	Explore
brush cell	3 studies	33% ± 22%	Explore
neuroendocrine cell	3 studies	39% ± 10%	Explore
microglial cell	3 studies	34% ± 14%	Explore
serous secreting cell	3 studies	60% ± 7%	Explore
intraepithelial lymphocyte	3 studies	53% ± 9%	Explore
neutrophil	3 studies	26% ± 7%	Explore
germinal center B cell	3 studies	47% ± 3%	Explore
myoepithelial cell	3 studies	42% ± 9%	Explore
neuron	3 studies	33% ± 14%	Explore
inflammatory macrophage	3 studies	32% ± 5%	Explore
luminal cell of prostate epithelium	3 studies	31% ± 8%	Explore
granulocyte monocyte progenitor cell	3 studies	56% ± 19%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	61% ± 24%	Explore
hepatocyte	3 studies	52% ± 28%	Explore
keratinocyte	3 studies	63% ± 8%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	69% ± 4%	Explore
double-positive, alpha-beta thymocyte	3 studies	65% ± 8%	Explore
progenitor cell of mammary luminal epithelium	3 studies	68% ± 8%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	20 studies	52% ± 15%	Explore
lung	17 studies	42% ± 11%	Explore
intestine	12 studies	35% ± 13%	Explore
kidney	8 studies	39% ± 11%	Explore
bone marrow	6 studies	31% ± 12%	Explore
lymph node	6 studies	46% ± 12%	Explore
liver	6 studies	43% ± 19%	Explore
pancreas	5 studies	33% ± 17%	Explore
placenta	5 studies	35% ± 19%	Explore
uterus	4 studies	52% ± 17%	Explore
breast	4 studies	46% ± 8%	Explore
adrenal gland	3 studies	32% ± 12%	Explore
prostate	3 studies	38% ± 12%	Explore
brain	3 studies	30% ± 2%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
liver	100%	3523.65	226 / 226	100%	159.10	406 / 406
ovary	100%	2457.46	180 / 180	100%	160.92	430 / 430
pancreas	100%	3090.51	328 / 328	100%	173.43	178 / 178
uterus	100%	2961.18	170 / 170	100%	190.15	459 / 459
esophagus	100%	3978.29	1444 / 1445	100%	128.55	183 / 183
skin	100%	6395.43	1809 / 1809	100%	195.99	471 / 472
thymus	100%	3577.65	653 / 653	100%	184.79	603 / 605
kidney	100%	3859.04	89 / 89	100%	158.78	897 / 901
intestine	100%	3285.55	966 / 966	99%	228.23	523 / 527
prostate	100%	4115.11	245 / 245	99%	295.56	498 / 502
stomach	100%	3336.69	359 / 359	99%	181.40	283 / 286
bladder	100%	3415.48	21 / 21	99%	234.65	498 / 504
adrenal gland	100%	5163.43	258 / 258	99%	137.50	227 / 230
breast	100%	3896.10	459 / 459	98%	163.71	1100 / 1118
lung	100%	3201.06	576 / 578	99%	176.08	1140 / 1155
brain	91%	1094.90	2399 / 2642	99%	83.10	699 / 705
adipose	100%	3736.80	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	255.95	80 / 80
lymph node	0%	0	0 / 0	100%	353.01	29 / 29
spleen	100%	4421.59	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	189.45	45 / 45
ureter	0%	0	0 / 0	100%	442.54	1 / 1
blood vessel	99%	2334.34	1326 / 1335	0%	0	0 / 0
peripheral blood	98%	3722.05	908 / 929	0%	0	0 / 0
heart	95%	1549.62	816 / 861	0%	0	0 / 0
muscle	92%	1262.71	735 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0007625	Biological process	grooming behavior
GO_0044209	Biological process	AMP salvage
GO_0032264	Biological process	IMP salvage
GO_0006168	Biological process	adenine salvage
GO_0006166	Biological process	purine ribonucleoside salvage
GO_0032263	Biological process	GMP salvage
GO_0034774	Cellular component	secretory granule lumen
GO_0070062	Cellular component	extracellular exosome
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0005576	Cellular component	extracellular region
GO_0005737	Cellular component	cytoplasm
GO_0016208	Molecular function	AMP binding
GO_0003999	Molecular function	adenine phosphoribosyltransferase activity
GO_0005515	Molecular function	protein binding
GO_0002055	Molecular function	adenine binding

Gene name	APRT
Protein name	Adenine phosphoribosyltransferase (APRT) (EC 2.4.2.7) Adenine phosphoribosyltransferase adenine phosphoribosyltransferase (EC 2.4.2.7)
Synonyms
Description	FUNCTION: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. .
Accessions	ENST00000426324.6 [P07741-2] ENST00000569616.1 H3BQZ9 ENST00000563655.5 ENST00000378364.8 [P07741-1] H3BQF1 ENST00000568319.5 ENST00000567391.5 P07741 Q12898 H3BQB1 H3BSW3 ENST00000567713.5

APRT report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review