ANP32B | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
B cell	38 studies	50% ± 16%	Explore
natural killer cell	35 studies	41% ± 19%	Explore
endothelial cell	34 studies	35% ± 15%	Explore
fibroblast	33 studies	36% ± 15%	Explore
macrophage	32 studies	37% ± 12%	Explore
CD8-positive, alpha-beta T cell	32 studies	50% ± 23%	Explore
T cell	31 studies	48% ± 22%	Explore
CD4-positive, alpha-beta T cell	31 studies	58% ± 22%	Explore
conventional dendritic cell	28 studies	52% ± 17%	Explore
regulatory T cell	27 studies	58% ± 16%	Explore
classical monocyte	25 studies	45% ± 17%	Explore
smooth muscle cell	24 studies	40% ± 18%	Explore
pericyte	23 studies	40% ± 14%	Explore
non-classical monocyte	23 studies	52% ± 17%	Explore
memory B cell	20 studies	55% ± 12%	Explore
basal cell	20 studies	40% ± 16%	Explore
epithelial cell	20 studies	44% ± 23%	Explore
dendritic cell	19 studies	47% ± 24%	Explore
monocyte	19 studies	43% ± 16%	Explore
mature NK T cell	19 studies	36% ± 14%	Explore
naive B cell	19 studies	44% ± 11%	Explore
plasmacytoid dendritic cell	19 studies	47% ± 14%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	18 studies	59% ± 17%	Explore
mast cell	17 studies	40% ± 17%	Explore
gamma-delta T cell	17 studies	46% ± 14%	Explore
CD16-positive, CD56-dim natural killer cell, human	16 studies	41% ± 12%	Explore
endothelial cell of lymphatic vessel	15 studies	36% ± 12%	Explore
mucosal invariant T cell	15 studies	44% ± 15%	Explore
connective tissue cell	15 studies	47% ± 18%	Explore
CD16-negative, CD56-bright natural killer cell, human	14 studies	42% ± 13%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	14 studies	62% ± 16%	Explore
plasma cell	14 studies	44% ± 14%	Explore
CD4-positive, alpha-beta memory T cell	12 studies	58% ± 19%	Explore
CD8-positive, alpha-beta memory T cell	12 studies	51% ± 20%	Explore
myofibroblast cell	12 studies	43% ± 18%	Explore
vein endothelial cell	12 studies	36% ± 16%	Explore
endothelial cell of vascular tree	12 studies	36% ± 12%	Explore
myeloid cell	12 studies	50% ± 23%	Explore
erythrocyte	11 studies	48% ± 26%	Explore
plasmablast	11 studies	58% ± 23%	Explore
secretory cell	11 studies	36% ± 16%	Explore
effector memory CD8-positive, alpha-beta T cell	10 studies	49% ± 16%	Explore
innate lymphoid cell	10 studies	42% ± 13%	Explore
abnormal cell	10 studies	43% ± 13%	Explore
endothelial cell of artery	10 studies	27% ± 10%	Explore
ciliated cell	10 studies	36% ± 15%	Explore
platelet	9 studies	35% ± 7%	Explore
effector CD8-positive, alpha-beta T cell	9 studies	53% ± 21%	Explore
capillary endothelial cell	9 studies	31% ± 14%	Explore
T follicular helper cell	9 studies	53% ± 15%	Explore
club cell	8 studies	32% ± 18%	Explore
leukocyte	8 studies	45% ± 20%	Explore
progenitor cell	8 studies	66% ± 17%	Explore
hematopoietic stem cell	8 studies	85% ± 21%	Explore
type II pneumocyte	7 studies	39% ± 17%	Explore
goblet cell	7 studies	37% ± 15%	Explore
mesothelial cell	7 studies	57% ± 22%	Explore
alveolar macrophage	6 studies	45% ± 13%	Explore
hematopoietic precursor cell	6 studies	73% ± 30%	Explore
effector CD4-positive, alpha-beta T cell	6 studies	63% ± 22%	Explore
mononuclear phagocyte	6 studies	38% ± 19%	Explore
transit amplifying cell	6 studies	47% ± 22%	Explore
precursor B cell	6 studies	54% ± 22%	Explore
immature B cell	6 studies	58% ± 11%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	62% ± 17%	Explore
type I pneumocyte	5 studies	39% ± 16%	Explore
CD4-positive helper T cell	5 studies	38% ± 13%	Explore
central memory CD8-positive, alpha-beta T cell	5 studies	53% ± 18%	Explore
exhausted T cell	5 studies	56% ± 15%	Explore
ionocyte	5 studies	28% ± 9%	Explore
enteroendocrine cell	5 studies	47% ± 19%	Explore
erythroblast	5 studies	70% ± 25%	Explore
intestinal crypt stem cell	5 studies	45% ± 15%	Explore
pro-B cell	5 studies	61% ± 25%	Explore
T-helper 17 cell	5 studies	58% ± 23%	Explore
neuron	5 studies	54% ± 18%	Explore
double negative thymocyte	5 studies	69% ± 13%	Explore
granulocyte	5 studies	46% ± 17%	Explore
oligodendrocyte	5 studies	21% ± 6%	Explore
CD4-positive, alpha-beta cytotoxic T cell	4 studies	52% ± 23%	Explore
deuterosomal cell	4 studies	20% ± 6%	Explore
respiratory goblet cell	4 studies	30% ± 16%	Explore
pancreatic A cell	4 studies	41% ± 11%	Explore
type B pancreatic cell	4 studies	45% ± 20%	Explore
enterocyte	4 studies	34% ± 13%	Explore
IgA plasma cell	4 studies	23% ± 6%	Explore
IgG plasma cell	4 studies	22% ± 7%	Explore
lymphocyte	4 studies	48% ± 25%	Explore
megakaryocyte	4 studies	51% ± 13%	Explore
retina horizontal cell	4 studies	38% ± 15%	Explore
microglial cell	4 studies	25% ± 8%	Explore
adventitial cell	4 studies	19% ± 3%	Explore
muscle cell	4 studies	28% ± 15%	Explore
neutrophil	4 studies	22% ± 4%	Explore
germinal center B cell	4 studies	73% ± 12%	Explore
intermediate monocyte	4 studies	53% ± 24%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	26% ± 5%	Explore
megakaryocyte-erythroid progenitor cell	4 studies	76% ± 35%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	42% ± 9%	Explore
oligodendrocyte precursor cell	4 studies	31% ± 21%	Explore
duct epithelial cell	3 studies	19% ± 3%	Explore
precursor cell	3 studies	71% ± 24%	Explore
squamous epithelial cell	3 studies	35% ± 28%	Explore
pancreatic D cell	3 studies	43% ± 17%	Explore
kidney loop of Henle epithelial cell	3 studies	23% ± 7%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	53% ± 23%	Explore
neural crest cell	3 studies	76% ± 12%	Explore
thymocyte	3 studies	46% ± 31%	Explore
extravillous trophoblast	3 studies	65% ± 11%	Explore
placental villous trophoblast	3 studies	65% ± 9%	Explore
brush cell	3 studies	35% ± 19%	Explore
intraepithelial lymphocyte	3 studies	41% ± 26%	Explore
acinar cell	3 studies	41% ± 18%	Explore
myoepithelial cell	3 studies	47% ± 12%	Explore
glutamatergic neuron	3 studies	22% ± 4%	Explore
pancreatic ductal cell	3 studies	43% ± 16%	Explore
group 3 innate lymphoid cell	3 studies	62% ± 14%	Explore
melanocyte	3 studies	28% ± 12%	Explore
keratinocyte	3 studies	33% ± 7%	Explore
T-helper 1 cell	3 studies	67% ± 12%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	66% ± 5%	Explore
double-positive, alpha-beta thymocyte	3 studies	77% ± 7%	Explore
astrocyte	3 studies	16% ± 1%	Explore
progenitor cell of mammary luminal epithelium	3 studies	30% ± 9%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	19 studies	50% ± 13%	Explore
lung	17 studies	39% ± 15%	Explore
intestine	12 studies	37% ± 18%	Explore
lymph node	7 studies	50% ± 15%	Explore
brain	7 studies	22% ± 4%	Explore
kidney	6 studies	38% ± 13%	Explore
bone marrow	6 studies	43% ± 24%	Explore
liver	6 studies	43% ± 24%	Explore
eye	5 studies	24% ± 6%	Explore
pancreas	4 studies	42% ± 16%	Explore
placenta	4 studies	46% ± 19%	Explore
uterus	4 studies	46% ± 14%	Explore
breast	4 studies	32% ± 4%	Explore
prostate	3 studies	26% ± 9%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	7996.61	1445 / 1445	100%	309.53	183 / 183
ovary	100%	10768.74	180 / 180	100%	244.56	430 / 430
stomach	100%	7032.32	359 / 359	100%	315.49	286 / 286
uterus	100%	9089.32	170 / 170	100%	453.96	459 / 459
intestine	100%	9391.93	966 / 966	100%	385.77	526 / 527
prostate	100%	7023.84	245 / 245	100%	252.80	501 / 502
thymus	100%	7105.92	653 / 653	100%	358.92	603 / 605
lung	100%	8581.08	578 / 578	100%	296.54	1151 / 1155
brain	100%	5636.58	2635 / 2642	100%	237.06	704 / 705
bladder	100%	9147.48	21 / 21	99%	333.85	501 / 504
skin	100%	11842.94	1809 / 1809	99%	299.95	469 / 472
pancreas	99%	5878.01	325 / 328	100%	263.55	178 / 178
breast	100%	9662.72	459 / 459	99%	307.74	1106 / 1118
kidney	100%	5349.18	89 / 89	98%	182.39	886 / 901
adrenal gland	100%	5066.56	258 / 258	95%	178.19	219 / 230
liver	91%	2629.81	206 / 226	98%	159.51	396 / 406
adipose	100%	9635.85	1204 / 1204	0%	0	0 / 0
blood vessel	100%	9616.20	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	704.64	29 / 29
spleen	100%	8304.44	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	443.42	45 / 45
ureter	0%	0	0 / 0	100%	285.77	1 / 1
peripheral blood	99%	9013.48	918 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	99%	250.70	79 / 80
muscle	98%	4321.36	783 / 803	0%	0	0 / 0
heart	95%	3809.68	820 / 861	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0045596	Biological process	negative regulation of cell differentiation
GO_0001944	Biological process	vasculature development
GO_0006919	Biological process	activation of cysteine-type endopeptidase activity involved in apoptotic process
GO_0021591	Biological process	ventricular system development
GO_0046827	Biological process	positive regulation of protein export from nucleus
GO_0042981	Biological process	regulation of apoptotic process
GO_0060021	Biological process	roof of mouth development
GO_0048839	Biological process	inner ear development
GO_0006334	Biological process	nucleosome assembly
GO_0005730	Cellular component	nucleolus
GO_0070062	Cellular component	extracellular exosome
GO_0005654	Cellular component	nucleoplasm
GO_0005737	Cellular component	cytoplasm
GO_0005634	Cellular component	nucleus
GO_0070063	Molecular function	RNA polymerase binding
GO_0005515	Molecular function	protein binding
GO_0042393	Molecular function	histone binding

IV. Literature review

[source]

Gene name	ANP32B
Protein name	Acidic leucine-rich nuclear phosphoprotein 32 family member B (Acidic protein rich in leucines) (Putative HLA-DR-associated protein I-2) (PHAPI2) (Silver-stainable protein SSP29)
Synonyms	APRIL PHAPI2
Description	FUNCTION: Multifunctional protein that is involved in the regulation of many processes including cell proliferation, apoptosis, cell cycle progression or transcription . Regulates the proliferation of neuronal stem cells, differentiation of leukemic cells and progression from G1 to S phase of the cell cycle. As negative regulator of caspase-3-dependent apoptosis, may act as an antagonist of ANP32A in regulating tissue homeostasis . Exhibits histone chaperone properties, able to recruit histones to certain promoters, thus regulating the transcription of specific genes . Also plays an essential role in the nucleocytoplasmic transport of specific mRNAs via the uncommon nuclear mRNA export receptor XPO1/CRM1 . Participates in the regulation of adequate adaptive immune responses by acting on mRNA expression and cell proliferation (By similarity). .; FUNCTION: (Microbial infection) Plays an essential role in influenza A and B viral genome replication . Also plays a role in foamy virus mRNA export from the nucleus to the cytoplasm . .
Accessions	Q92688 ENST00000339399.5 [Q92688-1]

ANP32B report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review